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The map label for this gene is thrC [H]

Identifier: 119715980

GI number: 119715980

Start: 1855343

End: 1856440

Strand: Direct

Name: thrC [H]

Synonym: Noca_1745

Alternate gene names: 119715980

Gene position: 1855343-1856440 (Clockwise)

Preceding gene: 119715979

Following gene: 119715981

Centisome position: 37.21

GC content: 72.22

Gene sequence:

>1098_bases
GTGAATCCGACCGGCTTCACGCCCACCCACCAGTGGCGCGGTGTGATCGAGGAGTACCGGCAGCTGCTGCAGATCCCCGA
GGACACGGTGGCGGTGACGCTGCGCGAGGGCGGCACGCCGCTGGTCTTCTCGGAGTGGCTCTCCGGCCGGACCGGCGCCG
ACGTCTGGCTCAAGGTCGAGGGCGGCAACCCGACCGGGTCCTTCAAGGACCGCGGGATGACCGCCGCGATCTCGGTCGCG
AAGCACGAGGGCGCCGAGGCGGTCGTCTGTGCCTCGACCGGCAACACGTCCGCCTCGATGGCGGCCTACGCCGCGAAGGC
CGGGCTGAAGCCCCTCGTGCTGGTGCCCGAGGGCAAGATCGCCGCGGGGAAGATGGCCCAGGCGATCCTGCACGGCGCCC
AGGTGATCATGGTGCGCGGCAACTTCGACGACTGCCTCGGGCTGGCCAAGGGCCTCGCATGGGACTACCCCGTCGCGCTG
GTGAACTCGGTCAACCCGGTGCGGCTCGAGGGCCAGAAGACCGCGGCGTTCGAGATCGTCGACTTCCTCGGCGACGCCCC
GGACTTCCACCTGCTACCCGTCGGCAACGCCGGCAACATCTCGGCGTACTGGCTCGGCTACACCCAGTACGCCGACTGGG
GCCGGGCCACCAAGAGACCCGTGATGCGCGGCTTCCAGGCCGAGGGGGCGGCACCCCTGGTCACCGGTGAGCCGTTCCCG
GACCCCGAGACCCGCGCGACCGCGATCCGGATCGGCAACCCCGCATCGTGGAAGCTCGCCGCGGCGGCGCGCGACGAGTC
CGGCGGCCGGTTCGCTGCGGTGAGCGACGGCCAGATCCTGGCCGCCCAGCGCGAGCTGGCCTCCCGGGACGGCGTCTTCG
TCGAGCCCGCGTCGGCCGCCGGCATCGCGGGCCTGCTCGAGGAGCTCGCGGCCGGCGAGGACTACCGCGGCAGCACGGTC
GTCGTGACGGTGACCGGGCACGGTCTCAAGGACACGGCGACCGCGCTCGAGGGCTTCACCGAGAGCGGGAACAGCATCGT
CGACACCGTGATCGACGCCGAGGTGACCGCCGCGGCGCAGGCCGCCGGTCTCGCGTAA

Upstream 100 bases:

>100_bases
AGTCGACCGACGCGGCGTTGCGCGCCACCGTCGAGCACCTGCGCGAGATGGACATCGTGCGCGAGGTGACGTCCGTGATG
CGTGTCGAGGGGGCGACCGA

Downstream 100 bases:

>100_bases
CGGGCCGGCGTGGTCACCTTCGTCGACGGGCCGGTCCGGGTGTCGGTCCCGGCCACCTCCGCGAACCTCGGGCCGGGCTT
CGACTCGCTCGGCCTGGCCC

Product: L-threonine synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNPTGFTPTHQWRGVIEEYRQLLQIPEDTVAVTLREGGTPLVFSEWLSGRTGADVWLKVEGGNPTGSFKDRGMTAAISVA
KHEGAEAVVCASTGNTSASMAAYAAKAGLKPLVLVPEGKIAAGKMAQAILHGAQVIMVRGNFDDCLGLAKGLAWDYPVAL
VNSVNPVRLEGQKTAAFEIVDFLGDAPDFHLLPVGNAGNISAYWLGYTQYADWGRATKRPVMRGFQAEGAAPLVTGEPFP
DPETRATAIRIGNPASWKLAAAARDESGGRFAAVSDGQILAAQRELASRDGVFVEPASAAGIAGLLEELAAGEDYRGSTV
VVTVTGHGLKDTATALEGFTESGNSIVDTVIDAEVTAAAQAAGLA

Sequences:

>Translated_365_residues
MNPTGFTPTHQWRGVIEEYRQLLQIPEDTVAVTLREGGTPLVFSEWLSGRTGADVWLKVEGGNPTGSFKDRGMTAAISVA
KHEGAEAVVCASTGNTSASMAAYAAKAGLKPLVLVPEGKIAAGKMAQAILHGAQVIMVRGNFDDCLGLAKGLAWDYPVAL
VNSVNPVRLEGQKTAAFEIVDFLGDAPDFHLLPVGNAGNISAYWLGYTQYADWGRATKRPVMRGFQAEGAAPLVTGEPFP
DPETRATAIRIGNPASWKLAAAARDESGGRFAAVSDGQILAAQRELASRDGVFVEPASAAGIAGLLEELAAGEDYRGSTV
VVTVTGHGLKDTATALEGFTESGNSIVDTVIDAEVTAAAQAAGLA
>Mature_365_residues
MNPTGFTPTHQWRGVIEEYRQLLQIPEDTVAVTLREGGTPLVFSEWLSGRTGADVWLKVEGGNPTGSFKDRGMTAAISVA
KHEGAEAVVCASTGNTSASMAAYAAKAGLKPLVLVPEGKIAAGKMAQAILHGAQVIMVRGNFDDCLGLAKGLAWDYPVAL
VNSVNPVRLEGQKTAAFEIVDFLGDAPDFHLLPVGNAGNISAYWLGYTQYADWGRATKRPVMRGFQAEGAAPLVTGEPFP
DPETRATAIRIGNPASWKLAAAARDESGGRFAAVSDGQILAAQRELASRDGVFVEPASAAGIAGLLEELAAGEDYRGSTV
VVTVTGHGLKDTATALEGFTESGNSIVDTVIDAEVTAAAQAAGLA

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=106, Percent_Identity=34.9056603773585, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37979; Mature: 37979

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTGFTPTHQWRGVIEEYRQLLQIPEDTVAVTLREGGTPLVFSEWLSGRTGADVWLKVE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHHCCCCCCEEEEEEE
GGNPTGSFKDRGMTAAISVAKHEGAEAVVCASTGNTSASMAAYAAKAGLKPLVLVPEGKI
CCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCC
AAGKMAQAILHGAQVIMVRGNFDDCLGLAKGLAWDYPVALVNSVNPVRLEGQKTAAFEIV
CHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCHHHHHHH
DFLGDAPDFHLLPVGNAGNISAYWLGYTQYADWGRATKRPVMRGFQAEGAAPLVTGEPFP
HHHCCCCCEEEEECCCCCCEEEEEEEEHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCCC
DPETRATAIRIGNPASWKLAAAARDESGGRFAAVSDGQILAAQRELASRDGVFVEPASAA
CCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCEEEEHHHHHHHCCCEEEECCCHH
GIAGLLEELAAGEDYRGSTVVVTVTGHGLKDTATALEGFTESGNSIVDTVIDAEVTAAAQ
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHH
AAGLA
HCCCC
>Mature Secondary Structure
MNPTGFTPTHQWRGVIEEYRQLLQIPEDTVAVTLREGGTPLVFSEWLSGRTGADVWLKVE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHHCCCCCCEEEEEEE
GGNPTGSFKDRGMTAAISVAKHEGAEAVVCASTGNTSASMAAYAAKAGLKPLVLVPEGKI
CCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCC
AAGKMAQAILHGAQVIMVRGNFDDCLGLAKGLAWDYPVALVNSVNPVRLEGQKTAAFEIV
CHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCHHHHHHH
DFLGDAPDFHLLPVGNAGNISAYWLGYTQYADWGRATKRPVMRGFQAEGAAPLVTGEPFP
HHHCCCCCEEEEECCCCCCEEEEEEEEHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCCC
DPETRATAIRIGNPASWKLAAAARDESGGRFAAVSDGQILAAQRELASRDGVFVEPASAA
CCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCEEEEHHHHHHHCCCEEEECCCHH
GIAGLLEELAAGEDYRGSTVVVTVTGHGLKDTATALEGFTESGNSIVDTVIDAEVTAAAQ
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHH
AAGLA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]