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The map label for this gene is rpoE [H]

Identifier: 119715941

GI number: 119715941

Start: 1811664

End: 1812317

Strand: Direct

Name: rpoE [H]

Synonym: Noca_1706

Alternate gene names: 119715941

Gene position: 1811664-1812317 (Clockwise)

Preceding gene: 119715940

Following gene: 119715942

Centisome position: 36.34

GC content: 67.74

Gene sequence:

>654_bases
ATGACTGACCCCGACGTGACCCTGCCCGAGACCGTTCTCGACCCCGACCCCGTGGATCTCGCCACGGAGACCGAGGCCGA
GCGGTCCGCGCGCTTCGAGCGCGACGCGCTGCCCTTCCTCGACCAGCTCTACTCGGCCGGCATGCGGATGACCCGCAACC
CGGCCGACGCCGAGGACCTGGTGCAGGAGACGTTCGCCAAGGCGTACTCCTCCTTCCACCAGTTCAAGCCCGGCACGAAC
CTGAAGGCCTGGCTGTACCGCATCCTCACCAACACCTTCATCAACACCTACCGCAAGAAGCAGCGTCAGCCCCAGCAGTC
GATGTCCGAGGACGTGGAGGACTGGCAGCTGCACCGCGCCGAGTCGCACTCCTCGACCGGGTTGCGCTCGGCGGAGATGG
AGGCGCTCGAGCACCTGCCCGACTCCCAGGTCAAGGACGCCCTGCAGAGCCTGCCCGAGGAGTTCCGCCTCGCGGTCTAC
CTCGCCGACGTCGAGGGGTTCGCCTACAAGGAGATCGCCGAGATCATGGACACCCCGATCGGCACCGTGATGTCCCGGCT
GCACCGGGGCCGGCGCCAGCTGCGCGACATGCTCTCCGACTACGTCCGCGACAACGACCTGCTCACCGTCGGACGGGATG
GCGGCACGTCATGA

Upstream 100 bases:

>100_bases
TCGCCGGCGGCGGCCGGGGGAATGACGGCCCGGCCTGACGCGTTCACCTCGCATGCTCGCTGTGCTCGAACCGCCCGCCC
CGGGGCTAGTCTGGGGTGCG

Downstream 100 bases:

>100_bases
GCCACGACCACCGCCCAGAACCCAGCTCCGAGGACTGTGCGGACTTCCTCGAGCGGATCGTGTACTTCCTGGACAACGAG
CTCGACGAGGGCGACTGCTC

Product: sigma-70 region 2 domain-containing protein

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTDPDVTLPETVLDPDPVDLATETEAERSARFERDALPFLDQLYSAGMRMTRNPADAEDLVQETFAKAYSSFHQFKPGTN
LKAWLYRILTNTFINTYRKKQRQPQQSMSEDVEDWQLHRAESHSSTGLRSAEMEALEHLPDSQVKDALQSLPEEFRLAVY
LADVEGFAYKEIAEIMDTPIGTVMSRLHRGRRQLRDMLSDYVRDNDLLTVGRDGGTS

Sequences:

>Translated_217_residues
MTDPDVTLPETVLDPDPVDLATETEAERSARFERDALPFLDQLYSAGMRMTRNPADAEDLVQETFAKAYSSFHQFKPGTN
LKAWLYRILTNTFINTYRKKQRQPQQSMSEDVEDWQLHRAESHSSTGLRSAEMEALEHLPDSQVKDALQSLPEEFRLAVY
LADVEGFAYKEIAEIMDTPIGTVMSRLHRGRRQLRDMLSDYVRDNDLLTVGRDGGTS
>Mature_216_residues
TDPDVTLPETVLDPDPVDLATETEAERSARFERDALPFLDQLYSAGMRMTRNPADAEDLVQETFAKAYSSFHQFKPGTNL
KAWLYRILTNTFINTYRKKQRQPQQSMSEDVEDWQLHRAESHSSTGLRSAEMEALEHLPDSQVKDALQSLPEEFRLAVYL
ADVEGFAYKEIAEIMDTPIGTVMSRLHRGRRQLRDMLSDYVRDNDLLTVGRDGGTS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=154, Percent_Identity=35.7142857142857, Blast_Score=90, Evalue=9e-20,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 24804; Mature: 24673

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPDVTLPETVLDPDPVDLATETEAERSARFERDALPFLDQLYSAGMRMTRNPADAEDL
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VQETFAKAYSSFHQFKPGTNLKAWLYRILTNTFINTYRKKQRQPQQSMSEDVEDWQLHRA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ESHSSTGLRSAEMEALEHLPDSQVKDALQSLPEEFRLAVYLADVEGFAYKEIAEIMDTPI
HCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
GTVMSRLHRGRRQLRDMLSDYVRDNDLLTVGRDGGTS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure 
TDPDVTLPETVLDPDPVDLATETEAERSARFERDALPFLDQLYSAGMRMTRNPADAEDL
CCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VQETFAKAYSSFHQFKPGTNLKAWLYRILTNTFINTYRKKQRQPQQSMSEDVEDWQLHRA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ESHSSTGLRSAEMEALEHLPDSQVKDALQSLPEEFRLAVYLADVEGFAYKEIAEIMDTPI
HCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
GTVMSRLHRGRRQLRDMLSDYVRDNDLLTVGRDGGTS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]