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The map label for this gene is aroA [H]

Identifier: 119715935

GI number: 119715935

Start: 1805808

End: 1807100

Strand: Reverse

Name: aroA [H]

Synonym: Noca_1700

Alternate gene names: 119715935

Gene position: 1807100-1805808 (Counterclockwise)

Preceding gene: 119715936

Following gene: 119715934

Centisome position: 36.24

GC content: 74.09

Gene sequence:

>1293_bases
GTGACGACGCCCCCCGACTCCTTGGCGGACCCCTGGCTCGCACCCCGGGCGCGGCGCCCCGTCGACGCGGTCGTCACGCT
CCCGGGGAGCAAGTCGCTCACCAACCGCGCGCTCGTGCTGGCCGCGATGGCCGACGGGCCCTCCGTCGTACGCCGGGCGC
TGCGCTCGCGCGACTCCATGCTGATGGCGGCCGCACTGACCGCACTGGGATCGCAGGTCGACACCACCGGTGCGGACTGG
TTGGTGACGCCCGGCGCCTTCGACCGCGACGCCGCCGTCGACTGCGGCCTGGCGGGCACCGTGATGCGGTTCGTGCCGCC
GGTCGCCGGGCTGTCGACCGGAGCGGTCTCCTTCGACGGCGACCCGCACATGCGCAAGCGGCCGATCGGCGAGATCCTCG
GTGCGCTGCGCACCCTCGGCGTGTCGGTCGAGGGCGACACGCTGCCGTTCACGGTCCACGGCTCGGGCACGGTGCGGGGC
GGGACGGTCGTGGTCGACGCCTCGGCCTCCTCGCAGTTCATCTCCGCGCTGCTCCTCGCGGGCGCGCGGTACGACCACGG
CGTCGACGTACGCCACGACGGCAAGCCCGTGCCCTCCCTGCCGCACATCGACATGACCGTGGCGATGCTGCGCGAGCACG
GGGTCGAGGTGGACGGCGCTGACGCGAACCGATGGCGGGTCGCGCCCGGCCCGGTCCGCGCCGTCGACCACCTGATCGAG
CCGGACCTCTCCAACGCCGCGCCGTTCCTGGCCCTGGCGGCCGTGTCGGGAGGGACCGTGGTGGTCCGCGACTGGCCGCG
CTCGACCACGCAGGCCGGCGACGCGCTGCGCGACATCCTCACCGCGATGGGCTGCGAAGTGGGTTTCGTCGACGGTCCGG
ACAGCACCGGGCTGCGGGTCACCGGCAGCGGGACGCTGCTCGGCATCGACGTCGACCTGCACAACGTCGGCGAGCTCACG
CCCGCGGTCGCGGCGCTGTGCGCGCTCGCCGAGGCGCCGTCGCACCTGCGCGGCATCGCGCACATCCGCGGCCACGAGAC
CGACCGGCTCGCCGCCCTCGCGACGGAGCTCAGCGGGCTGGGCGCCGACGTCACCGAGCATGCCGACGGGCTGAGCATCC
GGCCCGCCCCACTGCATGGCGGCGTGTTCCACACCTACGCGGACCACCGGATGGCACACGCCGGGGTGATCATCGGCGCC
GCCGTCGAGGACGTGCTGGTCGAGAACGTCGCCACGACCGGCAAGACCTTCCCCGACTTCGCCGGCTTCTGGTCCGGGCT
GATCGAGGAGTGA

Upstream 100 bases:

>100_bases
GCCCGGCGTCAGGCCAGGCACCTCGCCAGCACCGCACGCCAGGAGGCCAAGCTCGCCAAGGCCAAGGTCGCCTGACCCCG
GCCGTCGATAGGGTGCGGGG

Downstream 100 bases:

>100_bases
GCGGGCGATGAGCCCCAAGGCGCGGGGACGCTACTCCGACCACGACGTCGAGCACTACGACCGTCCGCGCCGCCACACCC
GTCCGCGCACCAAGGAGCGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTTPPDSLADPWLAPRARRPVDAVVTLPGSKSLTNRALVLAAMADGPSVVRRALRSRDSMLMAAALTALGSQVDTTGADW
LVTPGAFDRDAAVDCGLAGTVMRFVPPVAGLSTGAVSFDGDPHMRKRPIGEILGALRTLGVSVEGDTLPFTVHGSGTVRG
GTVVVDASASSQFISALLLAGARYDHGVDVRHDGKPVPSLPHIDMTVAMLREHGVEVDGADANRWRVAPGPVRAVDHLIE
PDLSNAAPFLALAAVSGGTVVVRDWPRSTTQAGDALRDILTAMGCEVGFVDGPDSTGLRVTGSGTLLGIDVDLHNVGELT
PAVAALCALAEAPSHLRGIAHIRGHETDRLAALATELSGLGADVTEHADGLSIRPAPLHGGVFHTYADHRMAHAGVIIGA
AVEDVLVENVATTGKTFPDFAGFWSGLIEE

Sequences:

>Translated_430_residues
MTTPPDSLADPWLAPRARRPVDAVVTLPGSKSLTNRALVLAAMADGPSVVRRALRSRDSMLMAAALTALGSQVDTTGADW
LVTPGAFDRDAAVDCGLAGTVMRFVPPVAGLSTGAVSFDGDPHMRKRPIGEILGALRTLGVSVEGDTLPFTVHGSGTVRG
GTVVVDASASSQFISALLLAGARYDHGVDVRHDGKPVPSLPHIDMTVAMLREHGVEVDGADANRWRVAPGPVRAVDHLIE
PDLSNAAPFLALAAVSGGTVVVRDWPRSTTQAGDALRDILTAMGCEVGFVDGPDSTGLRVTGSGTLLGIDVDLHNVGELT
PAVAALCALAEAPSHLRGIAHIRGHETDRLAALATELSGLGADVTEHADGLSIRPAPLHGGVFHTYADHRMAHAGVIIGA
AVEDVLVENVATTGKTFPDFAGFWSGLIEE
>Mature_429_residues
TTPPDSLADPWLAPRARRPVDAVVTLPGSKSLTNRALVLAAMADGPSVVRRALRSRDSMLMAAALTALGSQVDTTGADWL
VTPGAFDRDAAVDCGLAGTVMRFVPPVAGLSTGAVSFDGDPHMRKRPIGEILGALRTLGVSVEGDTLPFTVHGSGTVRGG
TVVVDASASSQFISALLLAGARYDHGVDVRHDGKPVPSLPHIDMTVAMLREHGVEVDGADANRWRVAPGPVRAVDHLIEP
DLSNAAPFLALAAVSGGTVVVRDWPRSTTQAGDALRDILTAMGCEVGFVDGPDSTGLRVTGSGTLLGIDVDLHNVGELTP
AVAALCALAEAPSHLRGIAHIRGHETDRLAALATELSGLGADVTEHADGLSIRPAPLHGGVFHTYADHRMAHAGVIIGAA
VEDVLVENVATTGKTFPDFAGFWSGLIEE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=421, Percent_Identity=35.3919239904988, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320332, Length=469, Percent_Identity=30.4904051172708, Blast_Score=147, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 44491; Mature: 44360

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPDSLADPWLAPRARRPVDAVVTLPGSKSLTNRALVLAAMADGPSVVRRALRSRDSM
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LMAAALTALGSQVDTTGADWLVTPGAFDRDAAVDCGLAGTVMRFVPPVAGLSTGAVSFDG
HHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECC
DPHMRKRPIGEILGALRTLGVSVEGDTLPFTVHGSGTVRGGTVVVDASASSQFISALLLA
CCCHHHCCHHHHHHHHHHHCCEECCCEEEEEEECCCEECCCEEEEECCCHHHHHHHHHHH
GARYDHGVDVRHDGKPVPSLPHIDMTVAMLREHGVEVDGADANRWRVAPGPVRAVDHLIE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHC
PDLSNAAPFLALAAVSGGTVVVRDWPRSTTQAGDALRDILTAMGCEVGFVDGPDSTGLRV
CCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEE
TGSGTLLGIDVDLHNVGELTPAVAALCALAEAPSHLRGIAHIRGHETDRLAALATELSGL
ECCCEEEEEEECHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GADVTEHADGLSIRPAPLHGGVFHTYADHRMAHAGVIIGAAVEDVLVENVATTGKTFPDF
CCCHHHCCCCCEECCCCCCCCEEEHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCHH
AGFWSGLIEE
HHHHHHHHCC
>Mature Secondary Structure 
TTPPDSLADPWLAPRARRPVDAVVTLPGSKSLTNRALVLAAMADGPSVVRRALRSRDSM
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LMAAALTALGSQVDTTGADWLVTPGAFDRDAAVDCGLAGTVMRFVPPVAGLSTGAVSFDG
HHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECC
DPHMRKRPIGEILGALRTLGVSVEGDTLPFTVHGSGTVRGGTVVVDASASSQFISALLLA
CCCHHHCCHHHHHHHHHHHCCEECCCEEEEEEECCCEECCCEEEEECCCHHHHHHHHHHH
GARYDHGVDVRHDGKPVPSLPHIDMTVAMLREHGVEVDGADANRWRVAPGPVRAVDHLIE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHC
PDLSNAAPFLALAAVSGGTVVVRDWPRSTTQAGDALRDILTAMGCEVGFVDGPDSTGLRV
CCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEE
TGSGTLLGIDVDLHNVGELTPAVAALCALAEAPSHLRGIAHIRGHETDRLAALATELSGL
ECCCEEEEEEECHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GADVTEHADGLSIRPAPLHGGVFHTYADHRMAHAGVIIGAAVEDVLVENVATTGKTFPDF
CCCHHHCCCCCEECCCCCCCCEEEHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCHH
AGFWSGLIEE
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA