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The map label for this gene is cobC [H]

Identifier: 119715698

GI number: 119715698

Start: 1550284

End: 1550856

Strand: Direct

Name: cobC [H]

Synonym: Noca_1462

Alternate gene names: 119715698

Gene position: 1550284-1550856 (Clockwise)

Preceding gene: 119715697

Following gene: 119715700

Centisome position: 31.09

GC content: 75.57

Gene sequence:

>573_bases
GTGAACCAGCCGCCCGTCCACGAGCTCTGGGTCGTCCGGCACGGCGCCACCGAGTGGAGTCGCGACCACCGGCACACCTC
CACCACCGACCTGCCACTGCTGCCGGAGGGCGAGGAGGTCGCCCGGTCGCTGGCGCCGCGCCTCGCCGACGCCGGCTTCG
CACTGGTGCTGACCAGCCCGCGGCTGCGGGCGCGGCGGACCGCCGAGCTCGCCGGCTTCCCGGACGCGGTCCCCGACGAC
GACCTCGTCGAGTGGGCGTACGGCGACTACGAGGGCACCACGACCGAGGAGATCCGGGAGAAGGTGCCGGGCTGGACCGT
GTGGACCCACCCGACACCGGGCGGCGAGTCCGCCGCCGAGGTCACCCGCCGGCTGGACCGCGTCGTCGAGCGGGTGCGAC
GAGCCGATGGTCCGGTGCTGGCCTTCGGCCACGGGCACGCGCTGCGGGCGCTGGCCGCGCGCTGGCTGGCGCTCCCGGCC
ACCGACGGCCGGCACTTCCGCCTGGACACCGCTACCGTCTCGGTCCTCGGCTACGAGCGGGAGACGCCGGTCCTGCGCTG
CTGGAACTCCTGA

Upstream 100 bases:

>100_bases
GGGGTGCGGGTGAACCCGGCGAAGTCCGAGACGTTCCAGGTCCTGCCGGGCGACCGGGTCGTCGTGCTCGCCGACGACTG
AGCTGTGTTGTGATGGCCGG

Downstream 100 bases:

>100_bases
GGCAGGGGAGTGGCCCGCGGGCGCGCGTGCGAGGGCCGGCGGCTGGCGTCCGGTTGGCGGGTGGTGGTGGCGGGTCGAAG
GTCGGTGGTCGGTCTATGTC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MNQPPVHELWVVRHGATEWSRDHRHTSTTDLPLLPEGEEVARSLAPRLADAGFALVLTSPRLRARRTAELAGFPDAVPDD
DLVEWAYGDYEGTTTEEIREKVPGWTVWTHPTPGGESAAEVTRRLDRVVERVRRADGPVLAFGHGHALRALAARWLALPA
TDGRHFRLDTATVSVLGYERETPVLRCWNS

Sequences:

>Translated_190_residues
MNQPPVHELWVVRHGATEWSRDHRHTSTTDLPLLPEGEEVARSLAPRLADAGFALVLTSPRLRARRTAELAGFPDAVPDD
DLVEWAYGDYEGTTTEEIREKVPGWTVWTHPTPGGESAAEVTRRLDRVVERVRRADGPVLAFGHGHALRALAARWLALPA
TDGRHFRLDTATVSVLGYERETPVLRCWNS
>Mature_190_residues
MNQPPVHELWVVRHGATEWSRDHRHTSTTDLPLLPEGEEVARSLAPRLADAGFALVLTSPRLRARRTAELAGFPDAVPDD
DLVEWAYGDYEGTTTEEIREKVPGWTVWTHPTPGGESAAEVTRRLDRVVERVRRADGPVLAFGHGHALRALAARWLALPA
TDGRHFRLDTATVSVLGYERETPVLRCWNS

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1790856, Length=185, Percent_Identity=31.3513513513514, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786857, Length=193, Percent_Identity=30.0518134715026, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322896, Length=181, Percent_Identity=37.5690607734807, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 21211; Mature: 21211

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPPVHELWVVRHGATEWSRDHRHTSTTDLPLLPEGEEVARSLAPRLADAGFALVLTSP
CCCCCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
RLRARRTAELAGFPDAVPDDDLVEWAYGDYEGTTTEEIREKVPGWTVWTHPTPGGESAAE
CHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHH
VTRRLDRVVERVRRADGPVLAFGHGHALRALAARWLALPATDGRHFRLDTATVSVLGYER
HHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEHHEEEEECCCC
ETPVLRCWNS
CCCEEEECCC
>Mature Secondary Structure
MNQPPVHELWVVRHGATEWSRDHRHTSTTDLPLLPEGEEVARSLAPRLADAGFALVLTSP
CCCCCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
RLRARRTAELAGFPDAVPDDDLVEWAYGDYEGTTTEEIREKVPGWTVWTHPTPGGESAAE
CHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHH
VTRRLDRVVERVRRADGPVLAFGHGHALRALAARWLALPATDGRHFRLDTATVSVLGYER
HHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEHHEEEEECCCC
ETPVLRCWNS
CCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]