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The map label for this gene is mtrB [H]

Identifier: 119715670

GI number: 119715670

Start: 1518715

End: 1520349

Strand: Direct

Name: mtrB [H]

Synonym: Noca_1434

Alternate gene names: 119715670

Gene position: 1518715-1520349 (Clockwise)

Preceding gene: 119715669

Following gene: 119715671

Centisome position: 30.46

GC content: 73.52

Gene sequence:

>1635_bases
GTGCTCCACCTGCGCTCCCCGGGGAGCTCCCGCCGACTGCCGGAGTCCGTCCGCCGGGGGCTGACCTTCTGGCGGCGCTC
GATCCAGGCGCGGGTGGTCGCCAGCACCCTGATCCTCTCGGCAGCCGTCGTGAGCGTGGTGGGCTGGTTCCTGCTCCAGC
AGACCCGCGACGGCCTCCTCGAGCACCGGGTGGACGCCGTGGTCGCCGAGGCGAACGACGAGACGGCCGAGGCGCGCGAC
CTGCTCAGGTCGGCGTCGGGGATCGACAGCGACGCGTTCGGCCAGCAGCGGGCCCTGGCTGCCACGCTGATCCAGCGCGG
CGAGACCCGCGGTTTCGCGGTGGTGCTGGTCGGGCCCACCACCCCCGGGAGCCGGATCTCGGACGGCGGCGCCAACTTCA
CCCGCGGCCTCGACACCGACAGCGTCCCGCAGTCGTTGGAAGAGCACTTCGACGAGGGCACCGCGACCGCGTGGACGTAC
ACCACGATCCGCACGACCAGCCCCGCCGGGATCGTCACCGAGGAGCCCGGGATCGCGGTCGGCTCCCAGGTCCTGCTGCC
GGCGGACGCCGAGTCCTACACGCTCTACTACCTCTTCCCGCTCGACGAGCAGGAGGAGACCCTGGCGCTGGTCACCCGAG
CGCTGCTGACCGCCGGGGTCCTGCTGCTGGTGCTCGTCGCCGGCATGACCTGGCTGGTGACCAGGCAGGTCGTGACGCCG
ATCCGACTGGCGCGCAAGGTGGCCGAGCGGCTCGCGGCGGGACAGCTCCAGGAGCGGCTCAAGGTGTCCGGCGAGGACGA
CCTGGCTCGGCTGGCGACGTCGTTCAACCAGATGGCCAGCAACCTCCAGCGCCAGATCCGCCAGCTCGAGGAGCTGAGCC
GCGTGCAGCGACGGTTCGTCTCCGACGTCTCCCACGAGCTGCGGACGCCGCTCACCACGGTGCGGATGGCCGGCGACGTC
CTGCACGACGCGCGCGCGGGGTTCGACCCGGCCACCGCGCGCGCCGCGGAGCTCCTGCAGACCGAGCTGGACCGCTTCGA
GGTGCTGCTCGCCGACCTGCTGGAGATCAGCCGCTTCGACGCGCGCGCCGCCGTCCTCGAGCTCGACGACGTCAACCTCG
TCGACGTGGCCCACCGCATCGTCGACGTCACCCGCCCGCTCGCCGAGCAGCGCCACGTGCGGGTCGTCGTCACCGCGCCG
GACCACGCCTGCCTGGCCGAGGCGGACGTCCGGCGCGTCGAGCGGATCGTGCGCAACCTGGTCACCAACGCCATCGACCA
CGCCGCCGCCGACGGCCCGGACGCCGGCATCGTGGTGCACGTGGACGGCGACGACCATGCGGCGGCGATCGCGGTGCGCG
ACCACGGGGTCGGCCTCGCGCCGGGGGAGGCGTCGATGGTCTTCAACCGGTTCTGGCGTGCGGACCCGGCCCGCGCCCGG
ACCAGTGGCGGCACCGGCCTCGGCCTCTCGATCGCCCTCGAGGACACCCACCTGCACGGCGGATGGCTCCAGGCTTGGGG
TCGCCCGGGCGAGGGGGCACAGTTCCGGCTGACGCTGCCCCGGCGCGCCGGGGGCGTCCTGCGGCACAGCCCACTGCCGC
TCGTGCCCGCTGATGTCACGGAGCCGGTCTCATGA

Upstream 100 bases:

>100_bases
CAGCGGCTGCGCTCCAAGGTCGAGCATGATCCCGAGAACCCCGAGATCGTGGTGACGGTCCGCGGCGTGGGGTACAAGGC
CGGAACCCCGTAGGCCCGCG

Downstream 100 bases:

>100_bases
GGCGCGGCGTGCTGGCCGTCCTGGCCGGGATCCTGCTGGTGGCTCTCGCGAGTGGCTGCGTGCGCCTGCCGGGCAGCGGG
CCGGTGGTCGAGACCCGCTC

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MLHLRSPGSSRRLPESVRRGLTFWRRSIQARVVASTLILSAAVVSVVGWFLLQQTRDGLLEHRVDAVVAEANDETAEARD
LLRSASGIDSDAFGQQRALAATLIQRGETRGFAVVLVGPTTPGSRISDGGANFTRGLDTDSVPQSLEEHFDEGTATAWTY
TTIRTTSPAGIVTEEPGIAVGSQVLLPADAESYTLYYLFPLDEQEETLALVTRALLTAGVLLLVLVAGMTWLVTRQVVTP
IRLARKVAERLAAGQLQERLKVSGEDDLARLATSFNQMASNLQRQIRQLEELSRVQRRFVSDVSHELRTPLTTVRMAGDV
LHDARAGFDPATARAAELLQTELDRFEVLLADLLEISRFDARAAVLELDDVNLVDVAHRIVDVTRPLAEQRHVRVVVTAP
DHACLAEADVRRVERIVRNLVTNAIDHAAADGPDAGIVVHVDGDDHAAAIAVRDHGVGLAPGEASMVFNRFWRADPARAR
TSGGTGLGLSIALEDTHLHGGWLQAWGRPGEGAQFRLTLPRRAGGVLRHSPLPLVPADVTEPVS

Sequences:

>Translated_544_residues
MLHLRSPGSSRRLPESVRRGLTFWRRSIQARVVASTLILSAAVVSVVGWFLLQQTRDGLLEHRVDAVVAEANDETAEARD
LLRSASGIDSDAFGQQRALAATLIQRGETRGFAVVLVGPTTPGSRISDGGANFTRGLDTDSVPQSLEEHFDEGTATAWTY
TTIRTTSPAGIVTEEPGIAVGSQVLLPADAESYTLYYLFPLDEQEETLALVTRALLTAGVLLLVLVAGMTWLVTRQVVTP
IRLARKVAERLAAGQLQERLKVSGEDDLARLATSFNQMASNLQRQIRQLEELSRVQRRFVSDVSHELRTPLTTVRMAGDV
LHDARAGFDPATARAAELLQTELDRFEVLLADLLEISRFDARAAVLELDDVNLVDVAHRIVDVTRPLAEQRHVRVVVTAP
DHACLAEADVRRVERIVRNLVTNAIDHAAADGPDAGIVVHVDGDDHAAAIAVRDHGVGLAPGEASMVFNRFWRADPARAR
TSGGTGLGLSIALEDTHLHGGWLQAWGRPGEGAQFRLTLPRRAGGVLRHSPLPLVPADVTEPVS
>Mature_544_residues
MLHLRSPGSSRRLPESVRRGLTFWRRSIQARVVASTLILSAAVVSVVGWFLLQQTRDGLLEHRVDAVVAEANDETAEARD
LLRSASGIDSDAFGQQRALAATLIQRGETRGFAVVLVGPTTPGSRISDGGANFTRGLDTDSVPQSLEEHFDEGTATAWTY
TTIRTTSPAGIVTEEPGIAVGSQVLLPADAESYTLYYLFPLDEQEETLALVTRALLTAGVLLLVLVAGMTWLVTRQVVTP
IRLARKVAERLAAGQLQERLKVSGEDDLARLATSFNQMASNLQRQIRQLEELSRVQRRFVSDVSHELRTPLTTVRMAGDV
LHDARAGFDPATARAAELLQTELDRFEVLLADLLEISRFDARAAVLELDDVNLVDVAHRIVDVTRPLAEQRHVRVVVTAP
DHACLAEADVRRVERIVRNLVTNAIDHAAADGPDAGIVVHVDGDDHAAAIAVRDHGVGLAPGEASMVFNRFWRADPARAR
TSGGTGLGLSIALEDTHLHGGWLQAWGRPGEGAQFRLTLPRRAGGVLRHSPLPLVPADVTEPVS

Specific function: Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=332, Percent_Identity=28.0120481927711, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=27.972027972028, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786783, Length=330, Percent_Identity=26.3636363636364, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786912, Length=363, Percent_Identity=28.099173553719, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787894, Length=274, Percent_Identity=27.3722627737226, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=28.0334728033473, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=27.8225806451613, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87082128, Length=303, Percent_Identity=26.7326732673267, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=357, Percent_Identity=24.0896358543417, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=25.9016393442623, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=338, Percent_Identity=26.6272189349112, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081816, Length=369, Percent_Identity=25.7452574525745, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=300, Percent_Identity=28.6666666666667, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789808, Length=300, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=290, Percent_Identity=24.8275862068966, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59001; Mature: 59001

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLRSPGSSRRLPESVRRGLTFWRRSIQARVVASTLILSAAVVSVVGWFLLQQTRDGLL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRVDAVVAEANDETAEARDLLRSASGIDSDAFGQQRALAATLIQRGETRGFAVVLVGPT
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCCCCCEEEEEEECC
TPGSRISDGGANFTRGLDTDSVPQSLEEHFDEGTATAWTYTTIRTTSPAGIVTEEPGIAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEECCCCCCC
GSQVLLPADAESYTLYYLFPLDEQEETLALVTRALLTAGVLLLVLVAGMTWLVTRQVVTP
CCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLARKVAERLAAGQLQERLKVSGEDDLARLATSFNQMASNLQRQIRQLEELSRVQRRFV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDVSHELRTPLTTVRMAGDVLHDARAGFDPATARAAELLQTELDRFEVLLADLLEISRFD
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ARAAVLELDDVNLVDVAHRIVDVTRPLAEQRHVRVVVTAPDHACLAEADVRRVERIVRNL
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
VTNAIDHAAADGPDAGIVVHVDGDDHAAAIAVRDHGVGLAPGEASMVFNRFWRADPARAR
HHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHC
TSGGTGLGLSIALEDTHLHGGWLQAWGRPGEGAQFRLTLPRRAGGVLRHSPLPLVPADVT
CCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
EPVS
CCCC
>Mature Secondary Structure
MLHLRSPGSSRRLPESVRRGLTFWRRSIQARVVASTLILSAAVVSVVGWFLLQQTRDGLL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRVDAVVAEANDETAEARDLLRSASGIDSDAFGQQRALAATLIQRGETRGFAVVLVGPT
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCCCCCEEEEEEECC
TPGSRISDGGANFTRGLDTDSVPQSLEEHFDEGTATAWTYTTIRTTSPAGIVTEEPGIAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEECCCCCCC
GSQVLLPADAESYTLYYLFPLDEQEETLALVTRALLTAGVLLLVLVAGMTWLVTRQVVTP
CCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLARKVAERLAAGQLQERLKVSGEDDLARLATSFNQMASNLQRQIRQLEELSRVQRRFV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDVSHELRTPLTTVRMAGDVLHDARAGFDPATARAAELLQTELDRFEVLLADLLEISRFD
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ARAAVLELDDVNLVDVAHRIVDVTRPLAEQRHVRVVVTAPDHACLAEADVRRVERIVRNL
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
VTNAIDHAAADGPDAGIVVHVDGDDHAAAIAVRDHGVGLAPGEASMVFNRFWRADPARAR
HHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHC
TSGGTGLGLSIALEDTHLHGGWLQAWGRPGEGAQFRLTLPRRAGGVLRHSPLPLVPADVT
CCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
EPVS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA