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The map label for this gene is brpA [H]

Identifier: 119715634

GI number: 119715634

Start: 1476323

End: 1477768

Strand: Direct

Name: brpA [H]

Synonym: Noca_1398

Alternate gene names: 119715634

Gene position: 1476323-1477768 (Clockwise)

Preceding gene: 119715633

Following gene: 119715635

Centisome position: 29.61

GC content: 69.36

Gene sequence:

>1446_bases
ATGCCGCCCGTCTCTTCCCCCGGGTCGCACGACAGCCACGGTCCGCGCTTCACCGCGGTCGACCGCGCCGCTCGGGTGCG
CTTCCGCAGGGCCATGGCCCTGATGCTGATGACCCTGCTCCTGCCCGGCTCGGCCCAGCTCGTGGCCGGCAACCGCAAGG
TCGGCATCGTCGCCCTGCGGATCTGGTTCCTGCTGGTGGCGACCTCCCTGTCGACGCTGGTGGTCGGGGCCTTCTGGCAC
GAGCTGATCTTCCGGCTCGCCTCGGACACGTTCGCGCTGTTCTGGATCCGGTTCGGCCTGATGGCGCTCGCGACCGGCTG
GGCGGTGCTCTTCCTCGATGCCTGGCGGATCGGCCAGCCGCTCACGCTCTCCCTGGGGCACCGGCGAGCGGTCGTGGGTG
TGAACGGCGTGCTGTGCCTCACGGTGGCGGGTTCGCTGCTGTTCGGCGCTCATCTCGTCGGCGTGCAGCGGCACCTGATG
CTCACGATGTTCGGCAGCGACCAGGTCACGGGTGCCCACGACGGCCGCTACAACGTGCTGCTGCTGGGCGGCGACTCCGG
CGCCGGCCGATGGGGCCTGCGCCCGGACTCGATGACCATCGCGAGCATCGACGCCGACACCGGCCGCACCGTGCTGATCT
CGCTGCCGCGCAACATGCAGAACTTCCCGTTCGTGCGGGGGTCGGTGATGCACGAACAGTTCCCGGACGGCTTCGACGCC
GACTACCTCAACGGGGTCAGCACCTGGGCGGGCGACAACACCGAGCTGTTCCGCGGGTCCGACAACCCCGGCGTCGACGC
CACGATCATGGCTGTCGAGGGCATCACCGGCCTCGAGATCAACTACTGGGCGATGGTCAACCTCGAGGGGTTCAAGGACC
TGGTCGACGCGGTCGGCGGCGTCACCCTGAACGTGCGCCAGCCGATCCCGGTCGGCGGGCTCGGCGACGACGTCACCGGC
TACATCCAGCCCGGCGTGCGCAGGCTCGACGGTCACGACACGCTGTGGTTCGCCCGCGCCCGCGACGACTCCGACGACTA
CTCGCGGATGGCTCGCCAGAAGTGCGTGATGAACGCGATGCTCCAGCAGATCAGCCCGCAGGTCGCGCTGCGCAACTTCG
AGAAGATCGCCGACGCGAGCTCGGCGATGATCTCGACCAACATCCCGGGCAGCGAGGTGGACCGCTTCATCTCGCTGGCG
CTCGAGGCCCGGAACCAGAAGGTCTCGACCCTCTCGCTGGTGCCGCCGATGATCAACACCGCCGACCCGGACATCAAGCT
GATCAAGAAGAAGGTCACCGAGGCGATCGACCGCGCGGAGGGCACCGCCCCGCCGCCGACCAAGCACAAGCAGCACGACG
GCGACCCGGTCACCGGCGGCTCGATCGGCTCGCTCAGCACCGGCTACGCCGCCAACGAGGCCGACGACCTGGGCTCCGCC
TGCTAG

Upstream 100 bases:

>100_bases
GACTTCCCTCGGCGCGTCGCGCCGGGATGTGACGGGTGTGACTGGTGATACTGGCGGGCAGCAGCACCCTTCCCCGTTCC
ACTTGCAGAGAGGCATCTCG

Downstream 100 bases:

>100_bases
CGAGCGCCGACGGCGGGCTCGGCGGTGCGCCGGGGCGGGGGCCTCGGGAGGCTCGAGCGCCGTCGGCACCTAGGGTGGAC
GCGTGAGCCAGCCGTCCCAG

Product: cell envelope-related transcriptional attenuator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MPPVSSPGSHDSHGPRFTAVDRAARVRFRRAMALMLMTLLLPGSAQLVAGNRKVGIVALRIWFLLVATSLSTLVVGAFWH
ELIFRLASDTFALFWIRFGLMALATGWAVLFLDAWRIGQPLTLSLGHRRAVVGVNGVLCLTVAGSLLFGAHLVGVQRHLM
LTMFGSDQVTGAHDGRYNVLLLGGDSGAGRWGLRPDSMTIASIDADTGRTVLISLPRNMQNFPFVRGSVMHEQFPDGFDA
DYLNGVSTWAGDNTELFRGSDNPGVDATIMAVEGITGLEINYWAMVNLEGFKDLVDAVGGVTLNVRQPIPVGGLGDDVTG
YIQPGVRRLDGHDTLWFARARDDSDDYSRMARQKCVMNAMLQQISPQVALRNFEKIADASSAMISTNIPGSEVDRFISLA
LEARNQKVSTLSLVPPMINTADPDIKLIKKKVTEAIDRAEGTAPPPTKHKQHDGDPVTGGSIGSLSTGYAANEADDLGSA
C

Sequences:

>Translated_481_residues
MPPVSSPGSHDSHGPRFTAVDRAARVRFRRAMALMLMTLLLPGSAQLVAGNRKVGIVALRIWFLLVATSLSTLVVGAFWH
ELIFRLASDTFALFWIRFGLMALATGWAVLFLDAWRIGQPLTLSLGHRRAVVGVNGVLCLTVAGSLLFGAHLVGVQRHLM
LTMFGSDQVTGAHDGRYNVLLLGGDSGAGRWGLRPDSMTIASIDADTGRTVLISLPRNMQNFPFVRGSVMHEQFPDGFDA
DYLNGVSTWAGDNTELFRGSDNPGVDATIMAVEGITGLEINYWAMVNLEGFKDLVDAVGGVTLNVRQPIPVGGLGDDVTG
YIQPGVRRLDGHDTLWFARARDDSDDYSRMARQKCVMNAMLQQISPQVALRNFEKIADASSAMISTNIPGSEVDRFISLA
LEARNQKVSTLSLVPPMINTADPDIKLIKKKVTEAIDRAEGTAPPPTKHKQHDGDPVTGGSIGSLSTGYAANEADDLGSA
C
>Mature_480_residues
PPVSSPGSHDSHGPRFTAVDRAARVRFRRAMALMLMTLLLPGSAQLVAGNRKVGIVALRIWFLLVATSLSTLVVGAFWHE
LIFRLASDTFALFWIRFGLMALATGWAVLFLDAWRIGQPLTLSLGHRRAVVGVNGVLCLTVAGSLLFGAHLVGVQRHLML
TMFGSDQVTGAHDGRYNVLLLGGDSGAGRWGLRPDSMTIASIDADTGRTVLISLPRNMQNFPFVRGSVMHEQFPDGFDAD
YLNGVSTWAGDNTELFRGSDNPGVDATIMAVEGITGLEINYWAMVNLEGFKDLVDAVGGVTLNVRQPIPVGGLGDDVTGY
IQPGVRRLDGHDTLWFARARDDSDDYSRMARQKCVMNAMLQQISPQVALRNFEKIADASSAMISTNIPGSEVDRFISLAL
EARNQKVSTLSLVPPMINTADPDIKLIKKKVTEAIDRAEGTAPPPTKHKQHDGDPVTGGSIGSLSTGYAANEADDLGSAC

Specific function: Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell envelope (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 51824; Mature: 51693

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVSSPGSHDSHGPRFTAVDRAARVRFRRAMALMLMTLLLPGSAQLVAGNRKVGIVALR
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
IWFLLVATSLSTLVVGAFWHELIFRLASDTFALFWIRFGLMALATGWAVLFLDAWRIGQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCCC
LTLSLGHRRAVVGVNGVLCLTVAGSLLFGAHLVGVQRHLMLTMFGSDQVTGAHDGRYNVL
EEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCEEEE
LLGGDSGAGRWGLRPDSMTIASIDADTGRTVLISLPRNMQNFPFVRGSVMHEQFPDGFDA
EEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCCCC
DYLNGVSTWAGDNTELFRGSDNPGVDATIMAVEGITGLEINYWAMVNLEGFKDLVDAVGG
HHHCCCHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCEEEEEEEEECHHHHHHHHHHCC
VTLNVRQPIPVGGLGDDVTGYIQPGVRRLDGHDTLWFARARDDSDDYSRMARQKCVMNAM
EEEEECCCCCCCCCCCCCCHHHCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LQQISPQVALRNFEKIADASSAMISTNIPGSEVDRFISLALEARNQKVSTLSLVPPMINT
HHHHCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
ADPDIKLIKKKVTEAIDRAEGTAPPPTKHKQHDGDPVTGGSIGSLSTGYAANEADDLGSA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
C
C
>Mature Secondary Structure 
PPVSSPGSHDSHGPRFTAVDRAARVRFRRAMALMLMTLLLPGSAQLVAGNRKVGIVALR
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
IWFLLVATSLSTLVVGAFWHELIFRLASDTFALFWIRFGLMALATGWAVLFLDAWRIGQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCCC
LTLSLGHRRAVVGVNGVLCLTVAGSLLFGAHLVGVQRHLMLTMFGSDQVTGAHDGRYNVL
EEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCEEEE
LLGGDSGAGRWGLRPDSMTIASIDADTGRTVLISLPRNMQNFPFVRGSVMHEQFPDGFDA
EEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCCCC
DYLNGVSTWAGDNTELFRGSDNPGVDATIMAVEGITGLEINYWAMVNLEGFKDLVDAVGG
HHHCCCHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCEEEEEEEEECHHHHHHHHHHCC
VTLNVRQPIPVGGLGDDVTGYIQPGVRRLDGHDTLWFARARDDSDDYSRMARQKCVMNAM
EEEEECCCCCCCCCCCCCCHHHCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LQQISPQVALRNFEKIADASSAMISTNIPGSEVDRFISLALEARNQKVSTLSLVPPMINT
HHHHCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
ADPDIKLIKKKVTEAIDRAEGTAPPPTKHKQHDGDPVTGGSIGSLSTGYAANEADDLGSA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]