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The map label for this gene is pepN [H]

Identifier: 119715617

GI number: 119715617

Start: 1456642

End: 1459233

Strand: Reverse

Name: pepN [H]

Synonym: Noca_1381

Alternate gene names: 119715617

Gene position: 1459233-1456642 (Counterclockwise)

Preceding gene: 119715621

Following gene: 119715614

Centisome position: 29.27

GC content: 70.64

Gene sequence:

>2592_bases
ATGCGTCGCATGCCTGGAACCAACCTCACCCGGGACGAGGCCGCGACCCGCGCCGCGCTCCTGGACGTCACCTCGTACGC
CATCGACCTGGACCTCACGACCGGTGACGCGACCTTCGGCTCGACCACCACGATCCGATTCACCTGCACCGAGCCCGGTG
CCGAGACGTTCGCCGACCTCGTGGACGCGACCGTCCACGAGATCACCCTGAACGGCGAGCAGGTCGACCCGGCCACGGCG
TACGCCGACAGCCGGATCACCTTGACCGGCCTCGCGGCCGAGAACGAGCTGGTCGTGCGCGCCGACTGCACCTACTCCCG
CACCGGTGAGGGCCTGCACCGCTTCGTCGACCCCGCCGACGACCGGGTCTACACCTACTCCCAGTTCGAGGTCCCCGACG
CCCGGCGCGTGTACACGACCTTCGAGCAGCCCGACCTCAAGGCGCCGTTCCAGTTCACGGTGACGGCGCCGGAGGGCTGG
AAGGTCATCTCCAACTCCCCCACCCCTGAACCCGAGGTCCTGGACGGGGGGTCCAAGGGGGGCGGAGCCCCCCTTGTGGG
CGGAGCCCCCCTTGTGTGGCGCTTCGCGCCGACCAAGCCGCTCTCGACGTACGTCACCGCGATCGTCGCGGGCGAGTACC
ACGAGGTGCAGCACGTCTACAAGGGCAGGCACGGCGACATCCCGCTGGGCCACTACTGCCGCCAGTCGCTCGTCGAGCAC
CTCGACGTCGAGGAGCTCGTGAAGATCACCGAGCAGGGGTTCGGCTACTTCGAGGACGCCTTCGACTACCCCTACCCGTT
CGGCAAGTACGACCAGCTCTACGTGCCGGAGTACAACATGGGCGCGATGGAGAACGCCGGGTGCGTGACGCTGCGCGACG
AGTACCTCCCCCGCAGCCGCCAGGACCGCGCGTTCTACGAGTTCCGGGTCGAGGTCATCTTGCACGAGATGGCGCACATG
TGGTTCGGCGACCTCGTGACGATGAAGTGGTGGGACGACCTCTGGCTCAACGAGTCGTTCGCCGAGTGGGCGTGCTACCA
CGCCGCGGTCGAGGCCACGGAGTTCACCGAGGTCTGGACGGGCTTCACCAACGCCCGCAAGAACTGGGCCTACCGCCAGG
ACCAGCTGCCCAGCACGCACCCGATCGCCGCCGACAACGTCGACCTGCGCGCCGTCGAAGTCAACTTCGACGGCATCACC
TACGCCAAGGGCGCCTCGGTGCTCAAGCAGCTGGTCGCCTGGGTCGGCCTGGAGAACTTCCTGGAGGGCGTGCGCGCCTA
CTTCAAGGAGTTCGAGTACGGCAACACCGAGTTCAAGGACCTGCTGGCCGCCCTCGAGGCGTCCTCGGGCCGAGACCTCG
AGGCGTGGGCCCAGGAGTGGCTCCAGACCTCGGGCGTCAACACGCTCGCGGCCGAGTTCGAGCTCGACGACGAGGGCAAC
TACAGCTCCTTCGCGATCCGGCAGACCGCGGCGCCCGAGCAGCCGACGCTGCGCCGCCACCGGCTCGGCGTGGGTCTCTA
CGACGCCGCGGACGGCCGGCTGGTCCGCCGTACCTCCCTGGAGACGGACGTCGCCGGCGAGCTCACCGAGGTCGCGGAGC
TGGTCGGCCAGCGCCAGCCGGACCTGCTGCTGCTCAACGAGGGCGACCTGGCCTACGCGAAGATCCGCCTCGACGAGCGC
TCCCTGGCGAGCGTCGTGGGTGGCATCGCGACGCTCGACGACTCGCTCGCCCGCGCGCTCTGCTGGGGCGCGGCGTGGGA
CATGACCCGCGACGCGGAGATGAGCGCGACCGACTTCGTCGCCCTGGTGCTCAGCGGGATCGGCAGCGAGACCGACGCGT
TCGGCGTGAGCCGGATCCCGACGTACGCCGCCCAGGCCGCCACGCTCTACTCGGCCCCGGAGAACCGCGCCGCCCTGCGG
GCGACCTGGGAGCAGGGCCTGCGCAAGCTGCTCGACAACGCCGAGCCCGGCAGCGACCACCAGCTGTCGTTCGCGCGCGC
GTACGCCGGCGCCGCGCACAGCGACACGGCGGTCGCCGACCTCGAGGGCCTGCTCGACGGCACGCTCACGTTCCAGGGGC
TCGCGGTCGACACCGACCTCCGGTGGACCCTGCTCAGCGGTCTCGCGAAGAACGGCCGCGCCGACGCCGACCGGATCGCC
GAGGAGCTCGCCCGCGACAACACCATCTCCGGGCAGGAGCACGCCGCCGCCGCCCGGGCGCAGCGGCCCACCGCCGAGGC
GAAGGCCGAGGCGTGGGAGATCGCGATGGTCCGCGACGACGTCGCCAACGAGACCCAGCGCAGCGTGGTGCTCGCCTTCC
AGGTGTTCGGCCAGGACGAGGTGCTGGCGCCGTACGTCGAGAAGTACCTCGAGGCCGCCGACACCATGTGGGAGGAGAAG
GGCACCCAGCGGGCTTCGACCGCGCTGGAGTTCATCTTCCCCAAGCAGCTCGCCAGCCAGGACCTGCTCGACCGGGTGGA
CGCCTGGCTGGAGTCCTCCCCGGCGAACCCGGCCGCGAAGCGCTACGTGCGCGAGGGCCGCGCGGATGTCGCCCGGGCCT
TGGCCGCCCAGGCCAGGGACGCCCAGGCCTGA

Upstream 100 bases:

>100_bases
GAGGAAGAGCACGGCGACCTCGCGTGTCCGACCCGGCTCGCTCACGGGCTCATCATGCCGATGCATCTCCCTTTCCGGTG
ACCCCGGCCCGGGTGGCAGG

Downstream 100 bases:

>100_bases
GCCTCGGCACCCGCTGCAGCGTCGACCCGCCCGAGGCGCTCGGGCGGGTCGACCGCTCAGCTCAGCCTCGATGCTCGGAG
TGGAGGATGTCCGGTCCGCG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP [H]

Number of amino acids: Translated: 863; Mature: 863

Protein sequence:

>863_residues
MRRMPGTNLTRDEAATRAALLDVTSYAIDLDLTTGDATFGSTTTIRFTCTEPGAETFADLVDATVHEITLNGEQVDPATA
YADSRITLTGLAAENELVVRADCTYSRTGEGLHRFVDPADDRVYTYSQFEVPDARRVYTTFEQPDLKAPFQFTVTAPEGW
KVISNSPTPEPEVLDGGSKGGGAPLVGGAPLVWRFAPTKPLSTYVTAIVAGEYHEVQHVYKGRHGDIPLGHYCRQSLVEH
LDVEELVKITEQGFGYFEDAFDYPYPFGKYDQLYVPEYNMGAMENAGCVTLRDEYLPRSRQDRAFYEFRVEVILHEMAHM
WFGDLVTMKWWDDLWLNESFAEWACYHAAVEATEFTEVWTGFTNARKNWAYRQDQLPSTHPIAADNVDLRAVEVNFDGIT
YAKGASVLKQLVAWVGLENFLEGVRAYFKEFEYGNTEFKDLLAALEASSGRDLEAWAQEWLQTSGVNTLAAEFELDDEGN
YSSFAIRQTAAPEQPTLRRHRLGVGLYDAADGRLVRRTSLETDVAGELTEVAELVGQRQPDLLLLNEGDLAYAKIRLDER
SLASVVGGIATLDDSLARALCWGAAWDMTRDAEMSATDFVALVLSGIGSETDAFGVSRIPTYAAQAATLYSAPENRAALR
ATWEQGLRKLLDNAEPGSDHQLSFARAYAGAAHSDTAVADLEGLLDGTLTFQGLAVDTDLRWTLLSGLAKNGRADADRIA
EELARDNTISGQEHAAAARAQRPTAEAKAEAWEIAMVRDDVANETQRSVVLAFQVFGQDEVLAPYVEKYLEAADTMWEEK
GTQRASTALEFIFPKQLASQDLLDRVDAWLESSPANPAAKRYVREGRADVARALAAQARDAQA

Sequences:

>Translated_863_residues
MRRMPGTNLTRDEAATRAALLDVTSYAIDLDLTTGDATFGSTTTIRFTCTEPGAETFADLVDATVHEITLNGEQVDPATA
YADSRITLTGLAAENELVVRADCTYSRTGEGLHRFVDPADDRVYTYSQFEVPDARRVYTTFEQPDLKAPFQFTVTAPEGW
KVISNSPTPEPEVLDGGSKGGGAPLVGGAPLVWRFAPTKPLSTYVTAIVAGEYHEVQHVYKGRHGDIPLGHYCRQSLVEH
LDVEELVKITEQGFGYFEDAFDYPYPFGKYDQLYVPEYNMGAMENAGCVTLRDEYLPRSRQDRAFYEFRVEVILHEMAHM
WFGDLVTMKWWDDLWLNESFAEWACYHAAVEATEFTEVWTGFTNARKNWAYRQDQLPSTHPIAADNVDLRAVEVNFDGIT
YAKGASVLKQLVAWVGLENFLEGVRAYFKEFEYGNTEFKDLLAALEASSGRDLEAWAQEWLQTSGVNTLAAEFELDDEGN
YSSFAIRQTAAPEQPTLRRHRLGVGLYDAADGRLVRRTSLETDVAGELTEVAELVGQRQPDLLLLNEGDLAYAKIRLDER
SLASVVGGIATLDDSLARALCWGAAWDMTRDAEMSATDFVALVLSGIGSETDAFGVSRIPTYAAQAATLYSAPENRAALR
ATWEQGLRKLLDNAEPGSDHQLSFARAYAGAAHSDTAVADLEGLLDGTLTFQGLAVDTDLRWTLLSGLAKNGRADADRIA
EELARDNTISGQEHAAAARAQRPTAEAKAEAWEIAMVRDDVANETQRSVVLAFQVFGQDEVLAPYVEKYLEAADTMWEEK
GTQRASTALEFIFPKQLASQDLLDRVDAWLESSPANPAAKRYVREGRADVARALAAQARDAQA
>Mature_863_residues
MRRMPGTNLTRDEAATRAALLDVTSYAIDLDLTTGDATFGSTTTIRFTCTEPGAETFADLVDATVHEITLNGEQVDPATA
YADSRITLTGLAAENELVVRADCTYSRTGEGLHRFVDPADDRVYTYSQFEVPDARRVYTTFEQPDLKAPFQFTVTAPEGW
KVISNSPTPEPEVLDGGSKGGGAPLVGGAPLVWRFAPTKPLSTYVTAIVAGEYHEVQHVYKGRHGDIPLGHYCRQSLVEH
LDVEELVKITEQGFGYFEDAFDYPYPFGKYDQLYVPEYNMGAMENAGCVTLRDEYLPRSRQDRAFYEFRVEVILHEMAHM
WFGDLVTMKWWDDLWLNESFAEWACYHAAVEATEFTEVWTGFTNARKNWAYRQDQLPSTHPIAADNVDLRAVEVNFDGIT
YAKGASVLKQLVAWVGLENFLEGVRAYFKEFEYGNTEFKDLLAALEASSGRDLEAWAQEWLQTSGVNTLAAEFELDDEGN
YSSFAIRQTAAPEQPTLRRHRLGVGLYDAADGRLVRRTSLETDVAGELTEVAELVGQRQPDLLLLNEGDLAYAKIRLDER
SLASVVGGIATLDDSLARALCWGAAWDMTRDAEMSATDFVALVLSGIGSETDAFGVSRIPTYAAQAATLYSAPENRAALR
ATWEQGLRKLLDNAEPGSDHQLSFARAYAGAAHSDTAVADLEGLLDGTLTFQGLAVDTDLRWTLLSGLAKNGRADADRIA
EELARDNTISGQEHAAAARAQRPTAEAKAEAWEIAMVRDDVANETQRSVVLAFQVFGQDEVLAPYVEKYLEAADTMWEEK
GTQRASTALEFIFPKQLASQDLLDRVDAWLESSPANPAAKRYVREGRADVARALAAQARDAQA

Specific function: Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=451, Percent_Identity=29.490022172949, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI132814467, Length=385, Percent_Identity=29.8701298701299, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI157266300, Length=469, Percent_Identity=29.637526652452, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI310123622, Length=405, Percent_Identity=29.6296296296296, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI61742777, Length=362, Percent_Identity=29.5580110497238, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI61742775, Length=362, Percent_Identity=29.5580110497238, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI310133497, Length=419, Percent_Identity=29.1169451073986, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI194239713, Length=380, Percent_Identity=27.8947368421053, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI194306629, Length=347, Percent_Identity=30.2593659942363, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI11641261, Length=347, Percent_Identity=30.2593659942363, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI94818901, Length=435, Percent_Identity=27.5862068965517, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI94818891, Length=435, Percent_Identity=27.5862068965517, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI7019561, Length=449, Percent_Identity=25.6124721603563, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI4505029, Length=411, Percent_Identity=26.2773722627737, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI40316915, Length=334, Percent_Identity=23.9520958083832, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI54020718, Length=260, Percent_Identity=28.0769230769231, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1787163, Length=383, Percent_Identity=25.3263707571802, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71989076, Length=384, Percent_Identity=31.25, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71989071, Length=384, Percent_Identity=31.25, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115533278, Length=339, Percent_Identity=31.858407079646, Blast_Score=136, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI115533276, Length=339, Percent_Identity=31.858407079646, Blast_Score=136, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17565628, Length=336, Percent_Identity=29.7619047619048, Blast_Score=136, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17569221, Length=387, Percent_Identity=28.1653746770026, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71990873, Length=382, Percent_Identity=29.0575916230367, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI133903840, Length=327, Percent_Identity=27.5229357798165, Blast_Score=119, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17569225, Length=352, Percent_Identity=26.9886363636364, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193206928, Length=335, Percent_Identity=27.1641791044776, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193206926, Length=335, Percent_Identity=27.1641791044776, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71984339, Length=331, Percent_Identity=24.4712990936556, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544504, Length=423, Percent_Identity=24.3498817966903, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71984353, Length=218, Percent_Identity=27.5229357798165, Blast_Score=73, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=457, Percent_Identity=28.6652078774617, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6321837, Length=422, Percent_Identity=29.1469194312796, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322054, Length=418, Percent_Identity=23.2057416267943, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24655252, Length=476, Percent_Identity=28.3613445378151, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24655257, Length=476, Percent_Identity=28.3613445378151, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24655274, Length=476, Percent_Identity=28.3613445378151, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24655260, Length=476, Percent_Identity=28.3613445378151, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24655265, Length=476, Percent_Identity=28.3613445378151, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24655268, Length=476, Percent_Identity=28.3613445378151, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24651025, Length=356, Percent_Identity=30.8988764044944, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24651023, Length=356, Percent_Identity=30.8988764044944, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24651021, Length=356, Percent_Identity=30.8988764044944, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21358341, Length=375, Percent_Identity=31.4666666666667, Blast_Score=159, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24646514, Length=399, Percent_Identity=29.5739348370927, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24646516, Length=373, Percent_Identity=29.2225201072386, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646518, Length=373, Percent_Identity=29.2225201072386, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI221379089, Length=326, Percent_Identity=30.3680981595092, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24650973, Length=450, Percent_Identity=26.4444444444444, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI45550850, Length=450, Percent_Identity=26.4444444444444, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646510, Length=354, Percent_Identity=28.8135593220339, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24646512, Length=354, Percent_Identity=28.8135593220339, Blast_Score=136, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24651016, Length=311, Percent_Identity=30.8681672025724, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28571901, Length=325, Percent_Identity=30.1538461538462, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI161078673, Length=325, Percent_Identity=30.1538461538462, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI221458256, Length=328, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281362224, Length=328, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648790, Length=338, Percent_Identity=27.810650887574, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24648786, Length=330, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221330574, Length=364, Percent_Identity=25.2747252747253, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571792, Length=461, Percent_Identity=24.295010845987, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24648784, Length=336, Percent_Identity=25.297619047619, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281362221, Length=306, Percent_Identity=25.1633986928105, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24641062, Length=346, Percent_Identity=22.2543352601156, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584504, Length=345, Percent_Identity=23.768115942029, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012778
- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 95323; Mature: 95323

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRMPGTNLTRDEAATRAALLDVTSYAIDLDLTTGDATFGSTTTIRFTCTEPGAETFADL
CCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHH
VDATVHEITLNGEQVDPATAYADSRITLTGLAAENELVVRADCTYSRTGEGLHRFVDPAD
HHHHHHEEEECCCCCCCHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHCCCCC
DRVYTYSQFEVPDARRVYTTFEQPDLKAPFQFTVTAPEGWKVISNSPTPEPEVLDGGSKG
CCEEEEEEECCCCCHHHEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCC
GGAPLVGGAPLVWRFAPTKPLSTYVTAIVAGEYHEVQHVYKGRHGDIPLGHYCRQSLVEH
CCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LDVEELVKITEQGFGYFEDAFDYPYPFGKYDQLYVPEYNMGAMENAGCVTLRDEYLPRSR
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEHHHCCCCC
QDRAFYEFRVEVILHEMAHMWFGDLVTMKWWDDLWLNESFAEWACYHAAVEATEFTEVWT
CCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GFTNARKNWAYRQDQLPSTHPIAADNVDLRAVEVNFDGITYAKGASVLKQLVAWVGLENF
CHHHHHHCCCCHHCCCCCCCCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHHCHHHH
LEGVRAYFKEFEYGNTEFKDLLAALEASSGRDLEAWAQEWLQTSGVNTLAAEFELDDEGN
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
YSSFAIRQTAAPEQPTLRRHRLGVGLYDAADGRLVRRTSLETDVAGELTEVAELVGQRQP
CCEEEEECCCCCCCCCHHHHHCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
DLLLLNEGDLAYAKIRLDERSLASVVGGIATLDDSLARALCWGAAWDMTRDAEMSATDFV
CEEEEECCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ALVLSGIGSETDAFGVSRIPTYAAQAATLYSAPENRAALRATWEQGLRKLLDNAEPGSDH
HHHHHHCCCCCCCCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
QLSFARAYAGAAHSDTAVADLEGLLDGTLTFQGLAVDTDLRWTLLSGLAKNGRADADRIA
CHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHH
EELARDNTISGQEHAAAARAQRPTAEAKAEAWEIAMVRDDVANETQRSVVLAFQVFGQDE
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHEEEEEHHHHHCCHHHHHEEEEEEECCCCC
VLAPYVEKYLEAADTMWEEKGTQRASTALEFIFPKQLASQDLLDRVDAWLESSPANPAAK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
RYVREGRADVARALAAQARDAQA
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRMPGTNLTRDEAATRAALLDVTSYAIDLDLTTGDATFGSTTTIRFTCTEPGAETFADL
CCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHH
VDATVHEITLNGEQVDPATAYADSRITLTGLAAENELVVRADCTYSRTGEGLHRFVDPAD
HHHHHHEEEECCCCCCCHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHCCCCC
DRVYTYSQFEVPDARRVYTTFEQPDLKAPFQFTVTAPEGWKVISNSPTPEPEVLDGGSKG
CCEEEEEEECCCCCHHHEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCC
GGAPLVGGAPLVWRFAPTKPLSTYVTAIVAGEYHEVQHVYKGRHGDIPLGHYCRQSLVEH
CCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LDVEELVKITEQGFGYFEDAFDYPYPFGKYDQLYVPEYNMGAMENAGCVTLRDEYLPRSR
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEHHHCCCCC
QDRAFYEFRVEVILHEMAHMWFGDLVTMKWWDDLWLNESFAEWACYHAAVEATEFTEVWT
CCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GFTNARKNWAYRQDQLPSTHPIAADNVDLRAVEVNFDGITYAKGASVLKQLVAWVGLENF
CHHHHHHCCCCHHCCCCCCCCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHHCHHHH
LEGVRAYFKEFEYGNTEFKDLLAALEASSGRDLEAWAQEWLQTSGVNTLAAEFELDDEGN
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
YSSFAIRQTAAPEQPTLRRHRLGVGLYDAADGRLVRRTSLETDVAGELTEVAELVGQRQP
CCEEEEECCCCCCCCCHHHHHCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
DLLLLNEGDLAYAKIRLDERSLASVVGGIATLDDSLARALCWGAAWDMTRDAEMSATDFV
CEEEEECCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ALVLSGIGSETDAFGVSRIPTYAAQAATLYSAPENRAALRATWEQGLRKLLDNAEPGSDH
HHHHHHCCCCCCCCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
QLSFARAYAGAAHSDTAVADLEGLLDGTLTFQGLAVDTDLRWTLLSGLAKNGRADADRIA
CHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHH
EELARDNTISGQEHAAAARAQRPTAEAKAEAWEIAMVRDDVANETQRSVVLAFQVFGQDE
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHEEEEEHHHHHCCHHHHHEEEEEEECCCCC
VLAPYVEKYLEAADTMWEEKGTQRASTALEFIFPKQLASQDLLDRVDAWLESSPANPAAK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
RYVREGRADVARALAAQARDAQA
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7909302; 7765336 [H]