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The map label for this gene is 119715483

Identifier: 119715483

GI number: 119715483

Start: 1322024

End: 1323577

Strand: Direct

Name: 119715483

Synonym: Noca_1247

Alternate gene names: NA

Gene position: 1322024-1323577 (Clockwise)

Preceding gene: 119715482

Following gene: 119715484

Centisome position: 26.52

GC content: 69.63

Gene sequence:

>1554_bases
ATGACCTACGGCGACACCGAGACAGGGGGCGCCGGCGCCGCCGGCGTGAGCGCGGCACGGCGAGAGATCGGGGTCACCGA
GCTGATCCTGCGCGACGCCCACCAGAGCCTGATGGCGACGCGGATGGCCCTCGAGGACATGGTCGACGCGTGCGCCGACA
TCGACGCGGCCGGCTACTGGTCCGTCGAGTGCTGGGGCGGCGCGACGTACGACGCCTGCATCCGCTTCCTCAACGAGGAC
CCGTGGGAGCGGCTGCGCACGTTCCGCCGGCTGCTGCCCAACAGCCGCCTCCAGATGTTGCTGCGCGGGCAGAACCTGCT
CGGCTACCGGCACTACGAGGACACGGTCGTCAACAAGTTCGTGGAGAAGTCGGCCGAGAACGGCATGGACGTCTACCGGA
CCTTCGACGCGCTCAACGACGTGCGCAACGTGCGGGAGGCGATCAAGGCCGTGCGCCGCGTCGGCAAGCACGCCCAGGGC
ACCATCTGCTACACCGAGAGCCCGCTGCACACGGTGCAGGGGTACGTCGACATGGCCCACGAGCTGATGGAGCTCGGCTG
CGACTCGCTGTGCCTCAAGGACATGGCGGCGCTGCTGCGGCCGCAGCCGGCCTTCGACATCGTCGGGGCGATCAAGCAGT
CGCTGGGCCAGGACGTCCGGGTGCACGTGCACTGCCACGCCACCACGGGCGTGACGCTGGTCAGCCTGATGAAGGCGATC
GAGGCGGGCGCCGACGTGGTCGACACCGCGATCTCGTCGGTCTCGATGGGCCCCGGCCACAACCCGACCGAGTCGCTGGT
CGAGATGCTCGCGGGCACGCCGTACGAGACCAAGCTCGACGACGCGCGGCTGCTCAAGATCAAGGACCACTTCGCGGTCG
TGCGGCCCAAGTACACCGAGTTCATGTCCGCGATCACCGGCGTCGAGACCGAGATCTTCAAGAGCCAGATCCCCGGCGGC
ATGATCTCGAACATGGAGTCGCAGCTGCGCCAGCAGGGCGCGGGTGACCGGCTCAAGGAGGTCCTCGAGGAGGTGCCGCG
GGTCCGCAAGGCCGCCGGCTACCCGCCGCTGGTGACTCCGTCCAGCCAGATCGTCGGCACCCAGGCCGTGTTCAACGTGC
TGATGGGCCCCTACCAGGTGCTCACCGCGGAGTTCGCCGACCTGATGCTGGGCTACTACGGCGAGGCGATCGGCCCCCGC
GACCCCGAGATCGTCGAGGCCGCCCGGCTGCAGACGAAGAAGGAGCCGATCGAGGTCCGGCCTGCCGACCTGCTCGAGCC
CGAGTGGGACAAGCTCTGCGCCGAGGCCAACGCCCTCGAGGGTGCCGACGGCACCGACGAGGACGTACTGACCTACGCGA
TGTTCCCGGGCGTCGCGCCGAAGTTCTTCCTCGAGCGGCCCGAGGGCCCGAGGAACGTCGGCAAGGACCCCGCGCAGCAG
GCGGCCGAGAAGCTCGCCGCCGCAGCGCCCGGCACCGGCCCGGTCACGGGCCCCATCCACTACGCCGTCTCGATGAACGG
CCGCAAGCACGACGTCACCGTCGAGCGAGCCTGA

Upstream 100 bases:

>100_bases
GACTCCGTTCCCGCGACGTCCCGGGACGGGCGGGCAACGGCCCGCCGACGTGGGACCAACGACCCGGGGCAGGCCCCGTG
CTGGCTGCCAGCATGAAGTC

Downstream 100 bases:

>100_bases
AGGGAATCCGGTGAGCAAGCACAAGCAGCACCAGGCCTCCATGGAGGAGCGCACCTCCGAGCTCGCGGAGCGGCGCCACA
AGGTCGAGCTCGGCGGCGGC

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: Transcarboxylase 5S subunit [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTYGDTETGGAGAAGVSAARREIGVTELILRDAHQSLMATRMALEDMVDACADIDAAGYWSVECWGGATYDACIRFLNED
PWERLRTFRRLLPNSRLQMLLRGQNLLGYRHYEDTVVNKFVEKSAENGMDVYRTFDALNDVRNVREAIKAVRRVGKHAQG
TICYTESPLHTVQGYVDMAHELMELGCDSLCLKDMAALLRPQPAFDIVGAIKQSLGQDVRVHVHCHATTGVTLVSLMKAI
EAGADVVDTAISSVSMGPGHNPTESLVEMLAGTPYETKLDDARLLKIKDHFAVVRPKYTEFMSAITGVETEIFKSQIPGG
MISNMESQLRQQGAGDRLKEVLEEVPRVRKAAGYPPLVTPSSQIVGTQAVFNVLMGPYQVLTAEFADLMLGYYGEAIGPR
DPEIVEAARLQTKKEPIEVRPADLLEPEWDKLCAEANALEGADGTDEDVLTYAMFPGVAPKFFLERPEGPRNVGKDPAQQ
AAEKLAAAAPGTGPVTGPIHYAVSMNGRKHDVTVERA

Sequences:

>Translated_517_residues
MTYGDTETGGAGAAGVSAARREIGVTELILRDAHQSLMATRMALEDMVDACADIDAAGYWSVECWGGATYDACIRFLNED
PWERLRTFRRLLPNSRLQMLLRGQNLLGYRHYEDTVVNKFVEKSAENGMDVYRTFDALNDVRNVREAIKAVRRVGKHAQG
TICYTESPLHTVQGYVDMAHELMELGCDSLCLKDMAALLRPQPAFDIVGAIKQSLGQDVRVHVHCHATTGVTLVSLMKAI
EAGADVVDTAISSVSMGPGHNPTESLVEMLAGTPYETKLDDARLLKIKDHFAVVRPKYTEFMSAITGVETEIFKSQIPGG
MISNMESQLRQQGAGDRLKEVLEEVPRVRKAAGYPPLVTPSSQIVGTQAVFNVLMGPYQVLTAEFADLMLGYYGEAIGPR
DPEIVEAARLQTKKEPIEVRPADLLEPEWDKLCAEANALEGADGTDEDVLTYAMFPGVAPKFFLERPEGPRNVGKDPAQQ
AAEKLAAAAPGTGPVTGPIHYAVSMNGRKHDVTVERA
>Mature_516_residues
TYGDTETGGAGAAGVSAARREIGVTELILRDAHQSLMATRMALEDMVDACADIDAAGYWSVECWGGATYDACIRFLNEDP
WERLRTFRRLLPNSRLQMLLRGQNLLGYRHYEDTVVNKFVEKSAENGMDVYRTFDALNDVRNVREAIKAVRRVGKHAQGT
ICYTESPLHTVQGYVDMAHELMELGCDSLCLKDMAALLRPQPAFDIVGAIKQSLGQDVRVHVHCHATTGVTLVSLMKAIE
AGADVVDTAISSVSMGPGHNPTESLVEMLAGTPYETKLDDARLLKIKDHFAVVRPKYTEFMSAITGVETEIFKSQIPGGM
ISNMESQLRQQGAGDRLKEVLEEVPRVRKAAGYPPLVTPSSQIVGTQAVFNVLMGPYQVLTAEFADLMLGYYGEAIGPRD
PEIVEAARLQTKKEPIEVRPADLLEPEWDKLCAEANALEGADGTDEDVLTYAMFPGVAPKFFLERPEGPRNVGKDPAQQA
AEKLAAAAPGTGPVTGPIHYAVSMNGRKHDVTVERA

Specific function: The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=454, Percent_Identity=34.1409691629956, Blast_Score=239, Evalue=6e-63,
Organism=Homo sapiens, GI106049295, Length=454, Percent_Identity=34.1409691629956, Blast_Score=239, Evalue=6e-63,
Organism=Homo sapiens, GI106049292, Length=454, Percent_Identity=34.1409691629956, Blast_Score=239, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17562816, Length=465, Percent_Identity=34.1935483870968, Blast_Score=246, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6319695, Length=453, Percent_Identity=32.6710816777042, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321376, Length=453, Percent_Identity=32.6710816777042, Blast_Score=241, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24652212, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652210, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652214, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI19921944, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652216, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI281363050, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652224, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652222, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652220, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24652218, Length=463, Percent_Identity=34.341252699784, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003379
- InterPro:   IPR000891 [H]

Pfam domain/function: PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 56466; Mature: 56335

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50991 PYR_CT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYGDTETGGAGAAGVSAARREIGVTELILRDAHQSLMATRMALEDMVDACADIDAAGYW
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
SVECWGGATYDACIRFLNEDPWERLRTFRRLLPNSRLQMLLRGQNLLGYRHYEDTVVNKF
EEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHCCHHHHHHHHHHH
VEKSAENGMDVYRTFDALNDVRNVREAIKAVRRVGKHAQGTICYTESPLHTVQGYVDMAH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHH
ELMELGCDSLCLKDMAALLRPQPAFDIVGAIKQSLGQDVRVHVHCHATTGVTLVSLMKAI
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHH
EAGADVVDTAISSVSMGPGHNPTESLVEMLAGTPYETKLDDARLLKIKDHFAVVRPKYTE
HHCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHEEEEHHHHHEECCHHHH
FMSAITGVETEIFKSQIPGGMISNMESQLRQQGAGDRLKEVLEEVPRVRKAAGYPPLVTP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SSQIVGTQAVFNVLMGPYQVLTAEFADLMLGYYGEAIGPRDPEIVEAARLQTKKEPIEVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
PADLLEPEWDKLCAEANALEGADGTDEDVLTYAMFPGVAPKFFLERPEGPRNVGKDPAQQ
CHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHH
AAEKLAAAAPGTGPVTGPIHYAVSMNGRKHDVTVERA
HHHHHHHCCCCCCCCCCCEEEEEEECCCEECCEEECC
>Mature Secondary Structure 
TYGDTETGGAGAAGVSAARREIGVTELILRDAHQSLMATRMALEDMVDACADIDAAGYW
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
SVECWGGATYDACIRFLNEDPWERLRTFRRLLPNSRLQMLLRGQNLLGYRHYEDTVVNKF
EEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHCCHHHHHHHHHHH
VEKSAENGMDVYRTFDALNDVRNVREAIKAVRRVGKHAQGTICYTESPLHTVQGYVDMAH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHH
ELMELGCDSLCLKDMAALLRPQPAFDIVGAIKQSLGQDVRVHVHCHATTGVTLVSLMKAI
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHH
EAGADVVDTAISSVSMGPGHNPTESLVEMLAGTPYETKLDDARLLKIKDHFAVVRPKYTE
HHCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHEEEEHHHHHEECCHHHH
FMSAITGVETEIFKSQIPGGMISNMESQLRQQGAGDRLKEVLEEVPRVRKAAGYPPLVTP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SSQIVGTQAVFNVLMGPYQVLTAEFADLMLGYYGEAIGPRDPEIVEAARLQTKKEPIEVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
PADLLEPEWDKLCAEANALEGADGTDEDVLTYAMFPGVAPKFFLERPEGPRNVGKDPAQQ
CHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHH
AAEKLAAAAPGTGPVTGPIHYAVSMNGRKHDVTVERA
HHHHHHHCCCCCCCCCCCEEEEEEECCCEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365490 [H]