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The map label for this gene is paaG [H]

Identifier: 119715441

GI number: 119715441

Start: 1279129

End: 1279923

Strand: Reverse

Name: paaG [H]

Synonym: Noca_1205

Alternate gene names: 119715441

Gene position: 1279923-1279129 (Counterclockwise)

Preceding gene: 119715442

Following gene: 119715435

Centisome position: 25.67

GC content: 72.33

Gene sequence:

>795_bases
ATGACCGAGCCCTCCGTCCTCCTCGACGTCACCGACGGCGTCGGGACCATCACGCTCAACCGTCCGGACGCCTACAACAG
CCTCGACGTGGCCACCAAGGAGCTGCTCCTCGAGACGGTGCGGGCCGTGGCCGACGACCCGGCGGTGCGCTGCGTGGTGC
TGACCGGCAGCGGCAGGGCCTTCTGCACCGGCCAGGACCTCAAGGAGCACATCGAGCTGCTCGAGAACGGCGGCAGCGAC
CTGCTGTTCACGACCGTGGACAAGCACTACAACCCGATCGTGACCACGCTGGCCGGCATGGCCAAGCCGGTGGTCGCGGC
CGTCAACGGGGTCGCGGCCGGCGCCGGGGCCAGCCTGGCGTTCGCCTGCGACCTGCGGATCCTGGCCGACACGGCCGGCT
TCAACCTCGCCTTCGCCAACGTCGCGCTGTCCTGTGACACCGGCGCGAGCTACCACCTCCAGCGGCTGGTCGGCCGCGCG
AAGGCGCTGGAGCTCCTCTACTTCCCGAGCACCGTCCCCGCCGCGGACGCGCTCGAGCTGGGTCTGGCCACCCGGGTGGT
GCCGGCCGACGAGCTGGCCGCCGAGGTCGGTGCCCTGGCCAGCCGATTGGCCGCCGGCCCGACGGTCGCGCTGGGGGCGA
TGCGGCAGTCCGTCGCGTACGCCGCCGGGCACTCCTTCGAGGAGTCGCTGGAGCTCGAGAGCGCGATGATGCAGAAGACC
GGCGCCACCGCCGACCACCGGGCCGCGGTCGCCGCCTTCGTCGCCAAGCAGAAGCCGGTGTTCGAGGGCCGGTGA

Upstream 100 bases:

>100_bases
CAAGCCGGGGGCCGACCGGTTCGTGGCCCGCTGCCTGGGCGACTGACACCGCCGTACCCGCCGGCCCCCGGCCCTCGGCC
CGACCTGACAGGATGCCCGC

Downstream 100 bases:

>100_bases
ACCGGTGTCCAGGGGTCGGTGAGCCGGGCCGGGACCCCGTCGCTCGGGGGCGACTCAACCCCGCCGGGCACCCCAGATGG
AGAGCACCTGCTTCGGCGCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTEPSVLLDVTDGVGTITLNRPDAYNSLDVATKELLLETVRAVADDPAVRCVVLTGSGRAFCTGQDLKEHIELLENGGSD
LLFTTVDKHYNPIVTTLAGMAKPVVAAVNGVAAGAGASLAFACDLRILADTAGFNLAFANVALSCDTGASYHLQRLVGRA
KALELLYFPSTVPAADALELGLATRVVPADELAAEVGALASRLAAGPTVALGAMRQSVAYAAGHSFEESLELESAMMQKT
GATADHRAAVAAFVAKQKPVFEGR

Sequences:

>Translated_264_residues
MTEPSVLLDVTDGVGTITLNRPDAYNSLDVATKELLLETVRAVADDPAVRCVVLTGSGRAFCTGQDLKEHIELLENGGSD
LLFTTVDKHYNPIVTTLAGMAKPVVAAVNGVAAGAGASLAFACDLRILADTAGFNLAFANVALSCDTGASYHLQRLVGRA
KALELLYFPSTVPAADALELGLATRVVPADELAAEVGALASRLAAGPTVALGAMRQSVAYAAGHSFEESLELESAMMQKT
GATADHRAAVAAFVAKQKPVFEGR
>Mature_263_residues
TEPSVLLDVTDGVGTITLNRPDAYNSLDVATKELLLETVRAVADDPAVRCVVLTGSGRAFCTGQDLKEHIELLENGGSDL
LFTTVDKHYNPIVTTLAGMAKPVVAAVNGVAAGAGASLAFACDLRILADTAGFNLAFANVALSCDTGASYHLQRLVGRAK
ALELLYFPSTVPAADALELGLATRVVPADELAAEVGALASRLAAGPTVALGAMRQSVAYAAGHSFEESLELESAMMQKTG
ATADHRAAVAAFVAKQKPVFEGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=31.7460317460317, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI31542718, Length=255, Percent_Identity=31.3725490196078, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI70995211, Length=244, Percent_Identity=28.6885245901639, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI45643119, Length=246, Percent_Identity=24.7967479674797, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI260275230, Length=246, Percent_Identity=24.7967479674797, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI260274832, Length=246, Percent_Identity=24.7967479674797, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI25453481, Length=254, Percent_Identity=26.3779527559055, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI51538573, Length=254, Percent_Identity=26.3779527559055, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757966, Length=241, Percent_Identity=27.3858921161826, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI51538581, Length=241, Percent_Identity=27.3858921161826, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757968, Length=259, Percent_Identity=26.2548262548263, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI49355787, Length=259, Percent_Identity=26.2548262548263, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI37594469, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI37594471, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=27.3764258555133, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=40.1544401544402, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787659, Length=248, Percent_Identity=31.8548387096774, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI221142681, Length=257, Percent_Identity=29.9610894941634, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=31.4176245210728, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=24.6153846153846, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790281, Length=187, Percent_Identity=28.3422459893048, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=258, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=29.6442687747036, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=28.0769230769231, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=247, Percent_Identity=27.9352226720648, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=260, Percent_Identity=25.7692307692308, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=197, Percent_Identity=31.4720812182741, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=209, Percent_Identity=31.5789473684211, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=23.7154150197628, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=248, Percent_Identity=27.8225806451613, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=192, Percent_Identity=28.6458333333333, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=192, Percent_Identity=28.6458333333333, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=31.4516129032258, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=31.4516129032258, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653139, Length=267, Percent_Identity=29.9625468164794, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19922422, Length=257, Percent_Identity=26.4591439688716, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920382, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24654903, Length=193, Percent_Identity=27.979274611399, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650670, Length=214, Percent_Identity=28.9719626168224, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357171, Length=228, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27313; Mature: 27182

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPSVLLDVTDGVGTITLNRPDAYNSLDVATKELLLETVRAVADDPAVRCVVLTGSGRA
CCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
FCTGQDLKEHIELLENGGSDLLFTTVDKHYNPIVTTLAGMAKPVVAAVNGVAAGAGASLA
EECHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
FACDLRILADTAGFNLAFANVALSCDTGASYHLQRLVGRAKALELLYFPSTVPAADALEL
EEEEEEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHH
GLATRVVPADELAAEVGALASRLAAGPTVALGAMRQSVAYAAGHSFEESLELESAMMQKT
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GATADHRAAVAAFVAKQKPVFEGR
CCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEPSVLLDVTDGVGTITLNRPDAYNSLDVATKELLLETVRAVADDPAVRCVVLTGSGRA
CCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
FCTGQDLKEHIELLENGGSDLLFTTVDKHYNPIVTTLAGMAKPVVAAVNGVAAGAGASLA
EECHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
FACDLRILADTAGFNLAFANVALSCDTGASYHLQRLVGRAKALELLYFPSTVPAADALEL
EEEEEEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHH
GLATRVVPADELAAEVGALASRLAAGPTVALGAMRQSVAYAAGHSFEESLELESAMMQKT
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GATADHRAAVAAFVAKQKPVFEGR
CCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]