Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 119715065

GI number: 119715065

Start: 862466

End: 863611

Strand: Direct

Name: mmgC [H]

Synonym: Noca_0818

Alternate gene names: 119715065

Gene position: 862466-863611 (Clockwise)

Preceding gene: 119715063

Following gene: 119715066

Centisome position: 17.3

GC content: 67.63

Gene sequence:

>1146_bases
GTGCTGGGCTCGATCTACGACTCGGAGCACGAATCGTTCCGGGGGTCGGTGCGGCAGTTCCTGGCACGGGAGGTGTGGCC
ACACGCCGACGCTCATCGCATCGCGGGAGGGTTCCCTCGCGAACTGTGGCTTGAGGCCGGACGGCAGGGCTATCTCGGGC
TATGCGTCCCCGAGTCCTACGGTGGCGCGGACGCCGATGACTACCGCTTCAACGCCGTGCTCATCGAGGAGCTCGCGCGG
GTCAACATGGCACTCGCCTCGTCGCTGAGCATCCACTTCGATGTGGTCGCGCCGTACCTGGTGGAGTTGACGACGCCCGA
ACAGCGCCAGCGGTGGTTGCCGGGGTTCGTCACCGGCGAGCTTGTCACAGCGATCGGGATGACCGAGCCGTCAGTCGGCT
CCGACCTGGCAGCCCTGCGCACGACGGCGGAACCGTGCTCCGAGGGGTGGCGCCTGAACGGCAGCAAGACCTTCATCACC
AACGGCTCCTCCGCGGACCTCGTCGTGGTCGCGGCGCGAACGACTCCCGGCAGCCGCTCGCGCGGCATCTCCCTATTCGC
GGTGGAGGCTGACCGGCGCGGCTTCAGCAGAGGCCGCAAGCTGGACAAGGTCGGGCAGCCTGAGGCGGACACGGCCGAGC
TCTTCTTCGAGGACCTCGTCCTCCCGGCGGAGAACCTGATCGGCACGCTTGATCGGGGCTTCCAGCACATGATGGGCGGC
CTGACGCAGGAGCGGATCGGCGCCGCGACCTCCAACATCGCCCACGCTGCGCAGATCCTGGACGAGACGCTCGGCTACGT
GCGCGAGCGCCGGGCCTTCGGGTCGCCGATCGGCAGCTTCCAGCACAACAAGTTCCTGCTCGCCGAACTCGCAACCCGCG
TCGAGGTGACGCAGACCTTCGTCCATCAGTGCGTGCTGGCCCATAGTCGCGGTGAGCTCACGCCCGTCGACGCCGCCAAG
GCCAAGTGGTGGAGCGCCGACGTGCAGAACGACGTGGTCGACCACTGCGTTCAGCTGCACGGCGGCTACGGCTTCATGAA
CGAGCAGCGAGTGGCGCGGGCCTGGCAGGACGCGCGGGTGACCAAGATCTGGGCCGGTTCCAACGAGATCATGAAGGAGT
TGATCGGCCGTGACCTGGGCCTGTGA

Upstream 100 bases:

>100_bases
CCGATCTCTTGACGGCGAGCTGGTTCGTCATGTTATCTAAGCTCGGAAGTTTCTAAGCGAGCGCTTAGAAACCAAAACGG
TAGCAGCGCGAGGAGACGGA

Downstream 100 bases:

>100_bases
GCGGATCGCCGGGGCTCGGGAGAACGTGCGATGAGGGGACGGTTCAAGGGACGCATCGCGCTGGTCACGGGCGCGAGCCG
AGGCATCGGGCTTGCGATCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLGSIYDSEHESFRGSVRQFLAREVWPHADAHRIAGGFPRELWLEAGRQGYLGLCVPESYGGADADDYRFNAVLIEELAR
VNMALASSLSIHFDVVAPYLVELTTPEQRQRWLPGFVTGELVTAIGMTEPSVGSDLAALRTTAEPCSEGWRLNGSKTFIT
NGSSADLVVVAARTTPGSRSRGISLFAVEADRRGFSRGRKLDKVGQPEADTAELFFEDLVLPAENLIGTLDRGFQHMMGG
LTQERIGAATSNIAHAAQILDETLGYVRERRAFGSPIGSFQHNKFLLAELATRVEVTQTFVHQCVLAHSRGELTPVDAAK
AKWWSADVQNDVVDHCVQLHGGYGFMNEQRVARAWQDARVTKIWAGSNEIMKELIGRDLGL

Sequences:

>Translated_381_residues
MLGSIYDSEHESFRGSVRQFLAREVWPHADAHRIAGGFPRELWLEAGRQGYLGLCVPESYGGADADDYRFNAVLIEELAR
VNMALASSLSIHFDVVAPYLVELTTPEQRQRWLPGFVTGELVTAIGMTEPSVGSDLAALRTTAEPCSEGWRLNGSKTFIT
NGSSADLVVVAARTTPGSRSRGISLFAVEADRRGFSRGRKLDKVGQPEADTAELFFEDLVLPAENLIGTLDRGFQHMMGG
LTQERIGAATSNIAHAAQILDETLGYVRERRAFGSPIGSFQHNKFLLAELATRVEVTQTFVHQCVLAHSRGELTPVDAAK
AKWWSADVQNDVVDHCVQLHGGYGFMNEQRVARAWQDARVTKIWAGSNEIMKELIGRDLGL
>Mature_381_residues
MLGSIYDSEHESFRGSVRQFLAREVWPHADAHRIAGGFPRELWLEAGRQGYLGLCVPESYGGADADDYRFNAVLIEELAR
VNMALASSLSIHFDVVAPYLVELTTPEQRQRWLPGFVTGELVTAIGMTEPSVGSDLAALRTTAEPCSEGWRLNGSKTFIT
NGSSADLVVVAARTTPGSRSRGISLFAVEADRRGFSRGRKLDKVGQPEADTAELFFEDLVLPAENLIGTLDRGFQHMMGG
LTQERIGAATSNIAHAAQILDETLGYVRERRAFGSPIGSFQHNKFLLAELATRVEVTQTFVHQCVLAHSRGELTPVDAAK
AKWWSADVQNDVVDHCVQLHGGYGFMNEQRVARAWQDARVTKIWAGSNEIMKELIGRDLGL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=43.7665782493369, Blast_Score=307, Evalue=1e-83,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=33.5120643431635, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=34.4117647058824, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=30.8093994778068, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=32.4468085106383, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=29.4429708222812, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=29.4429708222812, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=26.7379679144385, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI76496475, Length=334, Percent_Identity=30.8383233532934, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI4557235, Length=334, Percent_Identity=30.8383233532934, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=28.5714285714286, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=27.6595744680851, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI7669494, Length=352, Percent_Identity=28.4090909090909, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=26.643598615917, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=26.643598615917, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786223, Length=375, Percent_Identity=27.7333333333333, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=27.0557029177719, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI87082384, Length=311, Percent_Identity=25.7234726688103, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081702, Length=380, Percent_Identity=22.6315789473684, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=32.2666666666667, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=30.8510638297872, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=31.7333333333333, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=32.1808510638298, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=356, Percent_Identity=30.3370786516854, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=31.5217391304348, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=29.023746701847, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=356, Percent_Identity=29.2134831460674, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=27.5757575757576, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=345, Percent_Identity=28.1159420289855, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=29.136690647482, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=29.004329004329, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=280, Percent_Identity=27.5, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=22.8494623655914, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71982178, Length=265, Percent_Identity=26.0377358490566, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=23.4309623430962, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=290, Percent_Identity=25.5172413793103, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=31.8302387267904, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24660351, Length=365, Percent_Identity=31.5068493150685, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI21356377, Length=366, Percent_Identity=29.2349726775956, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24666513, Length=369, Percent_Identity=25.7452574525745, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=28.5333333333333, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=25.7309941520468, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=26.1213720316623, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24652780, Length=292, Percent_Identity=25, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41886; Mature: 41886

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSIYDSEHESFRGSVRQFLAREVWPHADAHRIAGGFPRELWLEAGRQGYLGLCVPESY
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHCCCCCCEEEECCCCC
GGADADDYRFNAVLIEELARVNMALASSLSIHFDVVAPYLVELTTPEQRQRWLPGFVTGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCHHHHHCCCCHHHHH
LVTAIGMTEPSVGSDLAALRTTAEPCSEGWRLNGSKTFITNGSSADLVVVAARTTPGSRS
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCEEEEEEECCCCCCC
RGISLFAVEADRRGFSRGRKLDKVGQPEADTAELFFEDLVLPAENLIGTLDRGFQHMMGG
CCEEEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
LTQERIGAATSNIAHAAQILDETLGYVRERRAFGSPIGSFQHNKFLLAELATRVEVTQTF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VHQCVLAHSRGELTPVDAAKAKWWSADVQNDVVDHCVQLHGGYGFMNEQRVARAWQDARV
HHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCE
TKIWAGSNEIMKELIGRDLGL
EEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLGSIYDSEHESFRGSVRQFLAREVWPHADAHRIAGGFPRELWLEAGRQGYLGLCVPESY
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHCCCCCCEEEECCCCC
GGADADDYRFNAVLIEELARVNMALASSLSIHFDVVAPYLVELTTPEQRQRWLPGFVTGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCHHHHHCCCCHHHHH
LVTAIGMTEPSVGSDLAALRTTAEPCSEGWRLNGSKTFITNGSSADLVVVAARTTPGSRS
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCEEEEEEECCCCCCC
RGISLFAVEADRRGFSRGRKLDKVGQPEADTAELFFEDLVLPAENLIGTLDRGFQHMMGG
CCEEEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
LTQERIGAATSNIAHAAQILDETLGYVRERRAFGSPIGSFQHNKFLLAELATRVEVTQTF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VHQCVLAHSRGELTPVDAAKAKWWSADVQNDVVDHCVQLHGGYGFMNEQRVARAWQDARV
HHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCE
TKIWAGSNEIMKELIGRDLGL
EEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]