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The map label for this gene is fbiC [H]

Identifier: 119715061

GI number: 119715061

Start: 857837

End: 860365

Strand: Direct

Name: fbiC [H]

Synonym: Noca_0814

Alternate gene names: 119715061

Gene position: 857837-860365 (Clockwise)

Preceding gene: 119715060

Following gene: 119715062

Centisome position: 17.21

GC content: 69.2

Gene sequence:

>2529_bases
ATGACGTCCTCGGTCACCCCCCATCAGATCCGTCGGGCGCTCACGCGCGCGGAGCGCGGCGCCTCCCTCGACATGGACGA
GGCCACCGCGCTGCTCGCGGCGAGTGGGGACGACCTCGACAGGCTGACGGCTGCGGCGGCGAGAGTACGTGACGCGGGAC
TGATGGCCGCCGGTCGACCCGGCGTGGTCACCTACTCCCCCAAGGTGTTCATCCCGGTCACCCGGCTCTGCCGCGACCGC
TGTCACTACTGCACGTTCGTCGAAACACCCGCTCAGGGCGCGCGGGACGGGCGGTCGCCCTACCTCACGCCCGACGAGAT
TCTGGAGATCGCTCGCCAAGGCGCCCGGCTCGGCTGCCTCGAAGCGCTGTTCACCCTCGGTGACCGACCCGAAGACCGGT
GGCCCGAGGCGCGGGACTGGCTCGACGAGCAGGGCTACGACTCGACGCTTGCCTATGTCCGCGCGATGTCCGTCTTGGTG
CTGGAGGAAACCGGCCTGCTGCCGCACCTGAACCCGGGCGTGATGTCGTGGGAGGAGCTCAACCTGCTCAGGCCGGTGTC
CGCATCGATGGGGATGATGCTGGAGACCACGTCGCGGCGGCTCTTCGAGTCACCCGGGCTCGCCCACTACGGTTCGCCCG
ACAAGGATCCCAAGGTGCGCCTCCGGGTCCTCGAGGACGCCGGGCGCCACGGCATCCCCTTCACGACCGGTGTGCTCGTC
GGGATCGGCGAGACCCTCGAAGAGCGGGCCCAGACGATCTTCGCCATTCGCACGACGTCGCGTGCCTATGGGGCGATCCA
GGAGGTGATCGTCCAGAACTTCCGCGCCAAGCCGGGCACGGTGATGCGCCACGTCGACGACCTCGGACTCGACGAGTACC
GCGCCGCCATCGCCGTCACCCGTCTCGTGCTAGGCCCGCGGGCGCGGATCCAGGCGCCTCCCAACCTGGTCGACAGCTCT
GCCGGCTCCAAGGAGTGCCGCCTGCTCCTCGGAGCGGGTGTCGACGACTGGGGTGGGGTCTCCCCGCTCACGCCCGACCA
CGTCAACCCCGAGCGGCCCTGGCCCTCGCTCGAGCGGCTGCGCGTCCTCACCGAGGCGAGCGGCTTCGAGCTGAAAGCCC
GCCTGACGGTGCATCCCGAATACGTCAGAGGCTCCCTCGAGCGGGGCCAGGCGTGGCTCGACCCGCGGATCGTCGGCCAC
GTCGCCGCGTTGGCCGGGCCAGATGGACTGGCTGTCCCCGGGATCCGTCCCACCGGCCTGCCGTGGCAGGAACCCGACGG
TGGCTTCTCCTCGGCGGGCCGCACAGACCTCCACGCCGCCGTCGACACCGAGGGTCGGTCGGCCGACCGGCGCAGCGACT
TCGACACTGTGTACGGCGACTGGGAGGCGGTTCGTGTGGCCGCCAGTCGCACGAACACCCCCGCCGCGCTCCATGCGGCG
GGCGGTGAAGCACTGCGTGCGGCGGAAAGGGATCCCGGCAACCTCTCCGACGAGCATGCGCTGGCGCTGATGACGGCCGA
GGGCGATCTACTGGCCCAGGTGGTGAAGCTCGCCGACGAGCTGCGCCGGGAGACCGTCGGCGACGACGTCACCTACGTCG
TCAACCGCAACATCAACTTCACGAACGTCTGCTACGTCGGATGTCGCTTCTGCGCCTTCGCGCAGCGCAAGACCGACGCC
GACGCCTACCAGCTCTCCTACGACGAGGTCGCCGACCGCGCCCAGGAAGCCTGGGACCTCGGCGCCACCGAGGTGTGCAT
GCAAGGCGGCATCGACCCGGAGCTTCCGGCGTCCGCGTACTTCGACATCGCAGCCGCGGTCACGCAGCAGGTGCCCGACA
TGCACGTGCACGCCTTCTCCCCGATGGAGGTCGTCAACGGCACCGCCCGGACGGGAATGTCCATCGAAGACTTCCTCATC
AAGGCCCGCGAAGCCGGGCTCGGCTCGCTGCCAGGCACGGCCGCTGAGATCCTCGACGACGAGGTCCGCTGGGTGCTGAC
CAAGGGCAAGCTTCCCACGTCCACCTGGATCGAGATCATCTCCACCGCGCACCGGATCGGGATCCCGACCACCTCAACCA
TGATGTACGGCCACGTCGACAACCCACGCCACTGGGTGCGGCACCTCAACGTCCTCAAGACCATCCAGGACGAGACAGGT
GGCTTCACCGAGTTCGTCCCGCTGCCGTTCGTGCACACATCTGCGCCGATCTACCTCGCCGGCGTCGCCCGTCCCGGCCC
CACTCACCGCGACAATCTGGCCGTGCACGCGATGGCCCGGATCCTTCTGCACGGCCGCATCGACAACATCCAGACCTCCT
GGGTCAAGCTCGGCGTCGACGGCACCCGCGCGATGCTCCGAGCCGGTGCCAACGACCTCGGTGGGACGCTGATGGAAGAG
ACGATCTCGCGGATGGCCGGCTCCGAGCACGGGTCTGCCAAGACCGTCCCCGAGCTGGTCGAGATCGGTGCTGGCATCGA
GCGTCCCGTCCGTGAGCGGACCACCCTCTACGACCGAGTCGCCTCGTGA

Upstream 100 bases:

>100_bases
TCGCGCGTGCCTTGGGGCGCCCGCCCCGCACGGCGGCCGAGGATCGTTGACCCCGCATCAGCGGGCTGCACCTGACTCAC
TCCCGAGAAAGCGAGTGGCG

Downstream 100 bases:

>100_bases
GAGCAGCCGCCGACCCCCTGCAGGACGTGCGGCTGCTGCTTCCGGTCAAGCGGCTATCCACGGCCAAGTCGCGTCTGTCC
TCGGATGCCGCAACGCGCCG

Product: FO synthase

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [H]

Number of amino acids: Translated: 842; Mature: 841

Protein sequence:

>842_residues
MTSSVTPHQIRRALTRAERGASLDMDEATALLAASGDDLDRLTAAAARVRDAGLMAAGRPGVVTYSPKVFIPVTRLCRDR
CHYCTFVETPAQGARDGRSPYLTPDEILEIARQGARLGCLEALFTLGDRPEDRWPEARDWLDEQGYDSTLAYVRAMSVLV
LEETGLLPHLNPGVMSWEELNLLRPVSASMGMMLETTSRRLFESPGLAHYGSPDKDPKVRLRVLEDAGRHGIPFTTGVLV
GIGETLEERAQTIFAIRTTSRAYGAIQEVIVQNFRAKPGTVMRHVDDLGLDEYRAAIAVTRLVLGPRARIQAPPNLVDSS
AGSKECRLLLGAGVDDWGGVSPLTPDHVNPERPWPSLERLRVLTEASGFELKARLTVHPEYVRGSLERGQAWLDPRIVGH
VAALAGPDGLAVPGIRPTGLPWQEPDGGFSSAGRTDLHAAVDTEGRSADRRSDFDTVYGDWEAVRVAASRTNTPAALHAA
GGEALRAAERDPGNLSDEHALALMTAEGDLLAQVVKLADELRRETVGDDVTYVVNRNINFTNVCYVGCRFCAFAQRKTDA
DAYQLSYDEVADRAQEAWDLGATEVCMQGGIDPELPASAYFDIAAAVTQQVPDMHVHAFSPMEVVNGTARTGMSIEDFLI
KAREAGLGSLPGTAAEILDDEVRWVLTKGKLPTSTWIEIISTAHRIGIPTTSTMMYGHVDNPRHWVRHLNVLKTIQDETG
GFTEFVPLPFVHTSAPIYLAGVARPGPTHRDNLAVHAMARILLHGRIDNIQTSWVKLGVDGTRAMLRAGANDLGGTLMEE
TISRMAGSEHGSAKTVPELVEIGAGIERPVRERTTLYDRVAS

Sequences:

>Translated_842_residues
MTSSVTPHQIRRALTRAERGASLDMDEATALLAASGDDLDRLTAAAARVRDAGLMAAGRPGVVTYSPKVFIPVTRLCRDR
CHYCTFVETPAQGARDGRSPYLTPDEILEIARQGARLGCLEALFTLGDRPEDRWPEARDWLDEQGYDSTLAYVRAMSVLV
LEETGLLPHLNPGVMSWEELNLLRPVSASMGMMLETTSRRLFESPGLAHYGSPDKDPKVRLRVLEDAGRHGIPFTTGVLV
GIGETLEERAQTIFAIRTTSRAYGAIQEVIVQNFRAKPGTVMRHVDDLGLDEYRAAIAVTRLVLGPRARIQAPPNLVDSS
AGSKECRLLLGAGVDDWGGVSPLTPDHVNPERPWPSLERLRVLTEASGFELKARLTVHPEYVRGSLERGQAWLDPRIVGH
VAALAGPDGLAVPGIRPTGLPWQEPDGGFSSAGRTDLHAAVDTEGRSADRRSDFDTVYGDWEAVRVAASRTNTPAALHAA
GGEALRAAERDPGNLSDEHALALMTAEGDLLAQVVKLADELRRETVGDDVTYVVNRNINFTNVCYVGCRFCAFAQRKTDA
DAYQLSYDEVADRAQEAWDLGATEVCMQGGIDPELPASAYFDIAAAVTQQVPDMHVHAFSPMEVVNGTARTGMSIEDFLI
KAREAGLGSLPGTAAEILDDEVRWVLTKGKLPTSTWIEIISTAHRIGIPTTSTMMYGHVDNPRHWVRHLNVLKTIQDETG
GFTEFVPLPFVHTSAPIYLAGVARPGPTHRDNLAVHAMARILLHGRIDNIQTSWVKLGVDGTRAMLRAGANDLGGTLMEE
TISRMAGSEHGSAKTVPELVEIGAGIERPVRERTTLYDRVAS
>Mature_841_residues
TSSVTPHQIRRALTRAERGASLDMDEATALLAASGDDLDRLTAAAARVRDAGLMAAGRPGVVTYSPKVFIPVTRLCRDRC
HYCTFVETPAQGARDGRSPYLTPDEILEIARQGARLGCLEALFTLGDRPEDRWPEARDWLDEQGYDSTLAYVRAMSVLVL
EETGLLPHLNPGVMSWEELNLLRPVSASMGMMLETTSRRLFESPGLAHYGSPDKDPKVRLRVLEDAGRHGIPFTTGVLVG
IGETLEERAQTIFAIRTTSRAYGAIQEVIVQNFRAKPGTVMRHVDDLGLDEYRAAIAVTRLVLGPRARIQAPPNLVDSSA
GSKECRLLLGAGVDDWGGVSPLTPDHVNPERPWPSLERLRVLTEASGFELKARLTVHPEYVRGSLERGQAWLDPRIVGHV
AALAGPDGLAVPGIRPTGLPWQEPDGGFSSAGRTDLHAAVDTEGRSADRRSDFDTVYGDWEAVRVAASRTNTPAALHAAG
GEALRAAERDPGNLSDEHALALMTAEGDLLAQVVKLADELRRETVGDDVTYVVNRNINFTNVCYVGCRFCAFAQRKTDAD
AYQLSYDEVADRAQEAWDLGATEVCMQGGIDPELPASAYFDIAAAVTQQVPDMHVHAFSPMEVVNGTARTGMSIEDFLIK
AREAGLGSLPGTAAEILDDEVRWVLTKGKLPTSTWIEIISTAHRIGIPTTSTMMYGHVDNPRHWVRHLNVLKTIQDETGG
FTEFVPLPFVHTSAPIYLAGVARPGPTHRDNLAVHAMARILLHGRIDNIQTSWVKLGVDGTRAMLRAGANDLGGTLMEET
ISRMAGSEHGSAKTVPELVEIGAGIERPVRERTTLYDRVAS

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) [H]

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the radical SAM superfamily. CofH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR019940
- InterPro:   IPR006638
- InterPro:   IPR019939
- InterPro:   IPR020050
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 91582; Mature: 91450

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSVTPHQIRRALTRAERGASLDMDEATALLAASGDDLDRLTAAAARVRDAGLMAAGRP
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCHHHHHHHHHHHHHCCCEECCCC
GVVTYSPKVFIPVTRLCRDRCHYCTFVETPAQGARDGRSPYLTPDEILEIARQGARLGCL
CEEEECCEEEEEHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH
EALFTLGDRPEDRWPEARDWLDEQGYDSTLAYVRAMSVLVLEETGLLPHLNPGVMSWEEL
HHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHH
NLLRPVSASMGMMLETTSRRLFESPGLAHYGSPDKDPKVRLRVLEDAGRHGIPFTTGVLV
HHHCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEHHCCCCCCCHHHHHHH
GIGETLEERAQTIFAIRTTSRAYGAIQEVIVQNFRAKPGTVMRHVDDLGLDEYRAAIAVT
HCHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
RLVLGPRARIQAPPNLVDSSAGSKECRLLLGAGVDDWGGVSPLTPDHVNPERPWPSLERL
HHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RVLTEASGFELKARLTVHPEYVRGSLERGQAWLDPRIVGHVAALAGPDGLAVPGIRPTGL
HHHHCCCCCEEEEEEEECHHHHHCCHHCCCHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC
PWQEPDGGFSSAGRTDLHAAVDTEGRSADRRSDFDTVYGDWEAVRVAASRTNTPAALHAA
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCHHHEEEEHHCCCCCCEEECC
GGEALRAAERDPGNLSDEHALALMTAEGDLLAQVVKLADELRRETVGDDVTYVVNRNINF
CCHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
TNVCYVGCRFCAFAQRKTDADAYQLSYDEVADRAQEAWDLGATEVCMQGGIDPELPASAY
HHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHH
FDIAAAVTQQVPDMHVHAFSPMEVVNGTARTGMSIEDFLIKAREAGLGSLPGTAAEILDD
HHHHHHHHHHCCCCEEECCCCHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCC
EVRWVLTKGKLPTSTWIEIISTAHRIGIPTTSTMMYGHVDNPRHWVRHLNVLKTIQDETG
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
GFTEFVPLPFVHTSAPIYLAGVARPGPTHRDNLAVHAMARILLHGRIDNIQTSWVKLGVD
CEEEECCCCEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GTRAMLRAGANDLGGTLMEETISRMAGSEHGSAKTVPELVEIGAGIERPVRERTTLYDRV
HHHHHHHCCCCHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
AS
CC
>Mature Secondary Structure 
TSSVTPHQIRRALTRAERGASLDMDEATALLAASGDDLDRLTAAAARVRDAGLMAAGRP
CCCCCHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCHHHHHHHHHHHHHCCCEECCCC
GVVTYSPKVFIPVTRLCRDRCHYCTFVETPAQGARDGRSPYLTPDEILEIARQGARLGCL
CEEEECCEEEEEHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH
EALFTLGDRPEDRWPEARDWLDEQGYDSTLAYVRAMSVLVLEETGLLPHLNPGVMSWEEL
HHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHH
NLLRPVSASMGMMLETTSRRLFESPGLAHYGSPDKDPKVRLRVLEDAGRHGIPFTTGVLV
HHHCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEHHCCCCCCCHHHHHHH
GIGETLEERAQTIFAIRTTSRAYGAIQEVIVQNFRAKPGTVMRHVDDLGLDEYRAAIAVT
HCHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
RLVLGPRARIQAPPNLVDSSAGSKECRLLLGAGVDDWGGVSPLTPDHVNPERPWPSLERL
HHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RVLTEASGFELKARLTVHPEYVRGSLERGQAWLDPRIVGHVAALAGPDGLAVPGIRPTGL
HHHHCCCCCEEEEEEEECHHHHHCCHHCCCHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC
PWQEPDGGFSSAGRTDLHAAVDTEGRSADRRSDFDTVYGDWEAVRVAASRTNTPAALHAA
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCHHHEEEEHHCCCCCCEEECC
GGEALRAAERDPGNLSDEHALALMTAEGDLLAQVVKLADELRRETVGDDVTYVVNRNINF
CCHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
TNVCYVGCRFCAFAQRKTDADAYQLSYDEVADRAQEAWDLGATEVCMQGGIDPELPASAY
HHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHH
FDIAAAVTQQVPDMHVHAFSPMEVVNGTARTGMSIEDFLIKAREAGLGSLPGTAAEILDD
HHHHHHHHHHCCCCEEECCCCHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCC
EVRWVLTKGKLPTSTWIEIISTAHRIGIPTTSTMMYGHVDNPRHWVRHLNVLKTIQDETG
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
GFTEFVPLPFVHTSAPIYLAGVARPGPTHRDNLAVHAMARILLHGRIDNIQTSWVKLGVD
CEEEECCCCEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GTRAMLRAGANDLGGTLMEETISRMAGSEHGSAKTVPELVEIGAGIERPVRERTTLYDRV
HHHHHHHCCCCHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA