| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is bhbA [H]
Identifier: 119715045
GI number: 119715045
Start: 840912
End: 842549
Strand: Direct
Name: bhbA [H]
Synonym: Noca_0798
Alternate gene names: 119715045
Gene position: 840912-842549 (Clockwise)
Preceding gene: 119715044
Following gene: 119715046
Centisome position: 16.87
GC content: 65.93
Gene sequence:
>1638_bases ATGACGAGTAGTGAAGCGTCGGGGTCCTCCGAGGTCACGACGGTCTCGGGGATTCCGCTCAAGGTCAGCTACGGCCCGAA CGACGTGCCGGAGACGGCAGCCCAGGCGGCGGCCGTGCTGCCGGGCGAAGCGCCCTACCTGCGCGGAGCACATGCTCAGG GGTACCGCTCCAAGCCGTGGCGGATCTTCCAGCTCTCGGGCTTCGGGAACCCCGAGGACGAGGCTGAGCGGATCCGGTAC CTGTTGTCGAAGGGCGGTACCGGTTTCATTATGGAGCACGACCGGATGACCGGTGATCATCTCTACGACGTCGACCATCC GGAGGTGGTCGCTCGTCGTGAGGACGTGGGCATCAGTGGTGCGGTGATCCTGTCGGCGCGAGACTTCGAGCTCGCGCTGA CCGGTATCGACCAGAGCAAGTACTTCGCCCATCCCGGCGGTGGGGTCTCTCAACACGCGGCCTTCGCGCTGGCCGGGTAC TGGACGGTGGCCGAACGTCGCGGCCTCGAGCTGCACAAGCTGAACGGGACGGGTCAGGCGGACTTCTTCCTGACCTACAT CGGATGCCCACCGCTCACTCAGATCCCACCGGCGGCAGCCCTCCGGGTGAACTGCGACATCGTCGAGTACGCAGCCAAGG TGGCGCCCAAGTGGACGCCCATCTCGATGGCGGCGTACAACGGCGCGGACAGCGGACTCAATGCCTACCAGGAGCTCGCC GCCCTGTTCGCGTGCTGCGTGTCGCACCTCGACGAGATCGTCGCGCGCGGCAACGTCCCGGTCGAGCAGGTCGCCTATGC CCTCGGGGGTGTCAGTTTCCGGGTGGCGATGGACTTCTTCGAAGACATCTGCAAGCTGCGCGTGGCCCGCAAGATGTGGC ATCGGCTCCTGACGACCCGGTACGGCATCACCGACCCGCGCGCGCTCAGCCTGCGTATCCACATCGTGACGGCCGGCTCG GCCATGACGTACCAGGAGCCGATCAACAACATCGTGCGGGGCACGGTCATGGGGATGGCAGCCGTTCTCGGCGGAGTCCA ATCCATCGGCGTTTCGGCGTACGACGAGGCGCTGTCGGTGCCGTCGGAGCAGGCGCACCGGCAGTCGCTGCGCGTCCAGC AGATCCTCATGCACGAGACGAACATCCCGGCGGTGGTGGACCCTCTCGGTGGCAGCTACTTTATCGAGTCCCTCTCGGCG GAGCTCGAGGAACGAGCATGGGCCGAGTTCGACCGGATCCTCGACAACGGGGGCTTCATCCAGAGCCTGGAGGACGGGTC GTTGCACCGCATGGCCGGTGAGAATGCCGTCGCCTTCCAGGACTCGATCACGAGCGGCGACCGCAAGATCGTCGGTGTCA ACCTGGGCGACAGCGACGGCGACCCTTTCGGCATCGATGGGTTCGAGGGGTCGCTCGACGCCTTCGAGCGCGGCATGGCG CGACTCAAGGACCTGCGCGCGTCACGAGACGGCAGGCATGTCTCGCGAGCGCTCGATCGCCTGGCGAACACGATGCGCAG CGGTGGAAACGTCATGTCCGGAGTGATGGACGCAGTGCGAGCAGACGCCTCGATCGGCGAGGTCGGCGACGTGTACAGGG AGGTGTTCGGATCATGGAAGTTCCCGGTGGACTTCTGA
Upstream 100 bases:
>100_bases TGCTCCGGAGGAGATGGCCTACATCGACACGTTTGGCAACCCCATCTCTGCCGGATCGTGACGAACCCGAACGAATCCGC CAGTCTGGAGAAGACGACTC
Downstream 100 bases:
>100_bases CCGGCGAGCCGGTTCGCACCCATGGCAAGCGGGTGCTCATGGCCAAGACCAGCCTCGACGGTCACTGGCGTGGCATCAAC GTGGTCTCGCGGGCACTGCG
Product: methylmalonyl-CoA mutase, large subunit
Products: NA
Alternate protein names: MCM [H]
Number of amino acids: Translated: 545; Mature: 544
Protein sequence:
>545_residues MTSSEASGSSEVTTVSGIPLKVSYGPNDVPETAAQAAAVLPGEAPYLRGAHAQGYRSKPWRIFQLSGFGNPEDEAERIRY LLSKGGTGFIMEHDRMTGDHLYDVDHPEVVARREDVGISGAVILSARDFELALTGIDQSKYFAHPGGGVSQHAAFALAGY WTVAERRGLELHKLNGTGQADFFLTYIGCPPLTQIPPAAALRVNCDIVEYAAKVAPKWTPISMAAYNGADSGLNAYQELA ALFACCVSHLDEIVARGNVPVEQVAYALGGVSFRVAMDFFEDICKLRVARKMWHRLLTTRYGITDPRALSLRIHIVTAGS AMTYQEPINNIVRGTVMGMAAVLGGVQSIGVSAYDEALSVPSEQAHRQSLRVQQILMHETNIPAVVDPLGGSYFIESLSA ELEERAWAEFDRILDNGGFIQSLEDGSLHRMAGENAVAFQDSITSGDRKIVGVNLGDSDGDPFGIDGFEGSLDAFERGMA RLKDLRASRDGRHVSRALDRLANTMRSGGNVMSGVMDAVRADASIGEVGDVYREVFGSWKFPVDF
Sequences:
>Translated_545_residues MTSSEASGSSEVTTVSGIPLKVSYGPNDVPETAAQAAAVLPGEAPYLRGAHAQGYRSKPWRIFQLSGFGNPEDEAERIRY LLSKGGTGFIMEHDRMTGDHLYDVDHPEVVARREDVGISGAVILSARDFELALTGIDQSKYFAHPGGGVSQHAAFALAGY WTVAERRGLELHKLNGTGQADFFLTYIGCPPLTQIPPAAALRVNCDIVEYAAKVAPKWTPISMAAYNGADSGLNAYQELA ALFACCVSHLDEIVARGNVPVEQVAYALGGVSFRVAMDFFEDICKLRVARKMWHRLLTTRYGITDPRALSLRIHIVTAGS AMTYQEPINNIVRGTVMGMAAVLGGVQSIGVSAYDEALSVPSEQAHRQSLRVQQILMHETNIPAVVDPLGGSYFIESLSA ELEERAWAEFDRILDNGGFIQSLEDGSLHRMAGENAVAFQDSITSGDRKIVGVNLGDSDGDPFGIDGFEGSLDAFERGMA RLKDLRASRDGRHVSRALDRLANTMRSGGNVMSGVMDAVRADASIGEVGDVYREVFGSWKFPVDF >Mature_544_residues TSSEASGSSEVTTVSGIPLKVSYGPNDVPETAAQAAAVLPGEAPYLRGAHAQGYRSKPWRIFQLSGFGNPEDEAERIRYL LSKGGTGFIMEHDRMTGDHLYDVDHPEVVARREDVGISGAVILSARDFELALTGIDQSKYFAHPGGGVSQHAAFALAGYW TVAERRGLELHKLNGTGQADFFLTYIGCPPLTQIPPAAALRVNCDIVEYAAKVAPKWTPISMAAYNGADSGLNAYQELAA LFACCVSHLDEIVARGNVPVEQVAYALGGVSFRVAMDFFEDICKLRVARKMWHRLLTTRYGITDPRALSLRIHIVTAGSA MTYQEPINNIVRGTVMGMAAVLGGVQSIGVSAYDEALSVPSEQAHRQSLRVQQILMHETNIPAVVDPLGGSYFIESLSAE LEERAWAEFDRILDNGGFIQSLEDGSLHRMAGENAVAFQDSITSGDRKIVGVNLGDSDGDPFGIDGFEGSLDAFERGMAR LKDLRASRDGRHVSRALDRLANTMRSGGNVMSGVMDAVRADASIGEVGDVYREVFGSWKFPVDF
Specific function: Catalyzes the interconversion of succinyl-CoA and methylmalonyl-CoA during the polyhydroxyalkanoate degradation pathway [H]
COG id: COG1884
COG function: function code I; Methylmalonyl-CoA mutase, N-terminal domain/subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 B12-binding domain [H]
Homologues:
Organism=Homo sapiens, GI156105689, Length=540, Percent_Identity=31.2962962962963, Blast_Score=237, Evalue=2e-62, Organism=Escherichia coli, GI1789284, Length=535, Percent_Identity=31.214953271028, Blast_Score=237, Evalue=2e-63, Organism=Caenorhabditis elegans, GI25144500, Length=536, Percent_Identity=31.3432835820896, Blast_Score=243, Evalue=2e-64,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006159 - InterPro: IPR016176 - InterPro: IPR014348 - InterPro: IPR006158 - InterPro: IPR006099 - InterPro: IPR006098 [H]
Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]
EC number: =5.4.99.2 [H]
Molecular weight: Translated: 58885; Mature: 58754
Theoretical pI: Translated: 5.07; Mature: 5.07
Prosite motif: PS00290 IG_MHC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSSEASGSSEVTTVSGIPLKVSYGPNDVPETAAQAAAVLPGEAPYLRGAHAQGYRSKPW CCCCCCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCE RIFQLSGFGNPEDEAERIRYLLSKGGTGFIMEHDRMTGDHLYDVDHPEVVARREDVGISG EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHCCCCCC AVILSARDFELALTGIDQSKYFAHPGGGVSQHAAFALAGYWTVAERRGLELHKLNGTGQA EEEEEECCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC DFFLTYIGCPPLTQIPPAAALRVNCDIVEYAAKVAPKWTPISMAAYNGADSGLNAYQELA EEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHH ALFACCVSHLDEIVARGNVPVEQVAYALGGVSFRVAMDFFEDICKLRVARKMWHRLLTTR HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YGITDPRALSLRIHIVTAGSAMTYQEPINNIVRGTVMGMAAVLGGVQSIGVSAYDEALSV CCCCCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC PSEQAHRQSLRVQQILMHETNIPAVVDPLGGSYFIESLSAELEERAWAEFDRILDNGGFI CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE QSLEDGSLHRMAGENAVAFQDSITSGDRKIVGVNLGDSDGDPFGIDGFEGSLDAFERGMA EECCCCCCHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH RLKDLRASRDGRHVSRALDRLANTMRSGGNVMSGVMDAVRADASIGEVGDVYREVFGSWK HHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC FPVDF CCCCC >Mature Secondary Structure TSSEASGSSEVTTVSGIPLKVSYGPNDVPETAAQAAAVLPGEAPYLRGAHAQGYRSKPW CCCCCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCE RIFQLSGFGNPEDEAERIRYLLSKGGTGFIMEHDRMTGDHLYDVDHPEVVARREDVGISG EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHCCCCCC AVILSARDFELALTGIDQSKYFAHPGGGVSQHAAFALAGYWTVAERRGLELHKLNGTGQA EEEEEECCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC DFFLTYIGCPPLTQIPPAAALRVNCDIVEYAAKVAPKWTPISMAAYNGADSGLNAYQELA EEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHH ALFACCVSHLDEIVARGNVPVEQVAYALGGVSFRVAMDFFEDICKLRVARKMWHRLLTTR HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YGITDPRALSLRIHIVTAGSAMTYQEPINNIVRGTVMGMAAVLGGVQSIGVSAYDEALSV CCCCCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC PSEQAHRQSLRVQQILMHETNIPAVVDPLGGSYFIESLSAELEERAWAEFDRILDNGGFI CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE QSLEDGSLHRMAGENAVAFQDSITSGDRKIVGVNLGDSDGDPFGIDGFEGSLDAFERGMA EECCCCCCHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH RLKDLRASRDGRHVSRALDRLANTMRSGGNVMSGVMDAVRADASIGEVGDVYREVFGSWK HHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC FPVDF CCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9889346; 11481431 [H]