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The map label for this gene is 119715030

Identifier: 119715030

GI number: 119715030

Start: 826035

End: 827201

Strand: Direct

Name: 119715030

Synonym: Noca_0783

Alternate gene names: NA

Gene position: 826035-827201 (Clockwise)

Preceding gene: 119715027

Following gene: 119715031

Centisome position: 16.57

GC content: 75.49

Gene sequence:

>1167_bases
ATGACTCGCGAGCACGACATCGTCCTGGTCGGCGCGACCGGCTTCACCGGCGGGCTGACCGCCGAGTACCTCCTGCGGCA
CGCCCCCGCGGGTCTGCGGTGGGCGCTGGCCGGCCGCAACCGGGAGAAGCTGGAGGCGGTCCGCGACCGGCTCGCCGACA
TCGATCCGGTGGCCGCCGACCTGCCGCTGCTGCACGCCGACACCACCGATCCGGGCGCGCTCGCGGACCTGGCGGCGGCC
ACCCGGGTCGTGATCACCACGGTGGGGCCCTACCTCGAGCACGGCGGCCCGCTCGTGGCCGCCTGCGCCGAGGCCGGCAC
CGACTACGTCGACCTCACCGGCGAGCCCGAGTTCGTCGACCGCACGTACGTCGAGCACCACGCCACCGCCCAGCGCACCG
GCGCCCGGATCGTGCACGCGTGCGGGTTCGACTCGGTTCCGCACGACCTCGGCGCGCTCTACACCGTCCAGCAGCTCGCC
GCGACCGGTCCGGTGCGGCTGCGCGGCGTGGTCCGCTCGGGCGCCACCTTCTCCGGCGGCACCTTCCACTCGGCGCTGGG
CCAGTTCTCCCGCGCCCGGCAGATGCGCACCGCGATGCAGGAGCGCCGTCGGGCCGAGCCGCGTCCCGAGGGCCGCCGCT
CGCGCGCGGTCTCCGGCAAGCCGCACCGCGACCCGCTGCTCGGCTACTGGCTGGTGCCGCTCCCCACGATCGACCCGTTC
GTCGTGGCCCGCAGCGGGGCCGCGCTGGCGGCGTACGGCCCGGACTTCTCCTACTCCCACTACGCCGGCACCAAGACGCT
GCGGTACGCCGCCGGCGGGGCCGCGGCCGCCGTCGCGGTGTTCGGCGCGGCCCAGGTCCCGCCGCTGCGACGCCTCCTGC
TCGGCCGGATCCCCCAGGGCGAGGGTCCCGACGAGCGGCGCCGGTCGAAGTCGTGGTTCACCGTCGACTTCGTCGGCGAG
GGCGACGGCCGCACCGTGCACACCCGCGTCTCCGGCGGCGACCCCGGCTACGACGAGACCGCGAAGATGCTCGCCGAGTC
CGCACTCTGCCTCGCGCTCGACGACAACCCGCCCACGTCCGGTCAGGTGACCACCGCCCAGGCGATGGGGGACAACCTGC
TCACCCGGCTCCAGGCGGCCGGGATCCGCTTCGAGACCCTCGACTAG

Upstream 100 bases:

>100_bases
TGGCCGGGGGCTCGAAGTTGTTGAGCGGGCGGATGTTGCGGCACATGACCCCGAGGGTACGTCGGCAGGCGGCTCGCCAG
CACTCTGCGAGCATGGCCCC

Downstream 100 bases:

>100_bases
CTGCGAAGCCGGGCCGGCCGGGGATCGCGGGCAGGCGCACAGCGGGTGGGCGCCCCAGGCAGGAGTCGAACCTGCGACCT
TTCGCTTAGGAGGCGGCTGC

Product: saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTREHDIVLVGATGFTGGLTAEYLLRHAPAGLRWALAGRNREKLEAVRDRLADIDPVAADLPLLHADTTDPGALADLAAA
TRVVITTVGPYLEHGGPLVAACAEAGTDYVDLTGEPEFVDRTYVEHHATAQRTGARIVHACGFDSVPHDLGALYTVQQLA
ATGPVRLRGVVRSGATFSGGTFHSALGQFSRARQMRTAMQERRRAEPRPEGRRSRAVSGKPHRDPLLGYWLVPLPTIDPF
VVARSGAALAAYGPDFSYSHYAGTKTLRYAAGGAAAAVAVFGAAQVPPLRRLLLGRIPQGEGPDERRRSKSWFTVDFVGE
GDGRTVHTRVSGGDPGYDETAKMLAESALCLALDDNPPTSGQVTTAQAMGDNLLTRLQAAGIRFETLD

Sequences:

>Translated_388_residues
MTREHDIVLVGATGFTGGLTAEYLLRHAPAGLRWALAGRNREKLEAVRDRLADIDPVAADLPLLHADTTDPGALADLAAA
TRVVITTVGPYLEHGGPLVAACAEAGTDYVDLTGEPEFVDRTYVEHHATAQRTGARIVHACGFDSVPHDLGALYTVQQLA
ATGPVRLRGVVRSGATFSGGTFHSALGQFSRARQMRTAMQERRRAEPRPEGRRSRAVSGKPHRDPLLGYWLVPLPTIDPF
VVARSGAALAAYGPDFSYSHYAGTKTLRYAAGGAAAAVAVFGAAQVPPLRRLLLGRIPQGEGPDERRRSKSWFTVDFVGE
GDGRTVHTRVSGGDPGYDETAKMLAESALCLALDDNPPTSGQVTTAQAMGDNLLTRLQAAGIRFETLD
>Mature_387_residues
TREHDIVLVGATGFTGGLTAEYLLRHAPAGLRWALAGRNREKLEAVRDRLADIDPVAADLPLLHADTTDPGALADLAAAT
RVVITTVGPYLEHGGPLVAACAEAGTDYVDLTGEPEFVDRTYVEHHATAQRTGARIVHACGFDSVPHDLGALYTVQQLAA
TGPVRLRGVVRSGATFSGGTFHSALGQFSRARQMRTAMQERRRAEPRPEGRRSRAVSGKPHRDPLLGYWLVPLPTIDPFV
VARSGAALAAYGPDFSYSHYAGTKTLRYAAGGAAAAVAVFGAAQVPPLRRLLLGRIPQGEGPDERRRSKSWFTVDFVGEG
DGRTVHTRVSGGDPGYDETAKMLAESALCLALDDNPPTSGQVTTAQAMGDNLLTRLQAAGIRFETLD

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=429, Percent_Identity=27.7389277389277, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17560066, Length=435, Percent_Identity=28.0459770114943, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32567112, Length=406, Percent_Identity=27.5862068965517, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71991033, Length=421, Percent_Identity=25.8907363420428, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644140, Length=439, Percent_Identity=29.8405466970387, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24644142, Length=439, Percent_Identity=29.8405466970387, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356081, Length=439, Percent_Identity=29.8405466970387, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24646278, Length=440, Percent_Identity=27.9545454545455, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 41350; Mature: 41219

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREHDIVLVGATGFTGGLTAEYLLRHAPAGLRWALAGRNREKLEAVRDRLADIDPVAAD
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHC
LPLLHADTTDPGALADLAAATRVVITTVGPYLEHGGPLVAACAEAGTDYVDLTGEPEFVD
CCEEECCCCCCHHHHHHHHHHEEEEEECCHHHHCCCCEEEHHHHCCCCEEEECCCCCHHH
RTYVEHHATAQRTGARIVHACGFDSVPHDLGALYTVQQLAATGPVRLRGVVRSGATFSGG
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCC
TFHSALGQFSRARQMRTAMQERRRAEPRPEGRRSRAVSGKPHRDPLLGYWLVPLPTIDPF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCE
VVARSGAALAAYGPDFSYSHYAGTKTLRYAAGGAAAAVAVFGAAQVPPLRRLLLGRIPQG
EEECCCCEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCC
EGPDERRRSKSWFTVDFVGEGDGRTVHTRVSGGDPGYDETAKMLAESALCLALDDNPPTS
CCCHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCC
GQVTTAQAMGDNLLTRLQAAGIRFETLD
CCEEEHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
TREHDIVLVGATGFTGGLTAEYLLRHAPAGLRWALAGRNREKLEAVRDRLADIDPVAAD
CCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHC
LPLLHADTTDPGALADLAAATRVVITTVGPYLEHGGPLVAACAEAGTDYVDLTGEPEFVD
CCEEECCCCCCHHHHHHHHHHEEEEEECCHHHHCCCCEEEHHHHCCCCEEEECCCCCHHH
RTYVEHHATAQRTGARIVHACGFDSVPHDLGALYTVQQLAATGPVRLRGVVRSGATFSGG
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCC
TFHSALGQFSRARQMRTAMQERRRAEPRPEGRRSRAVSGKPHRDPLLGYWLVPLPTIDPF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCE
VVARSGAALAAYGPDFSYSHYAGTKTLRYAAGGAAAAVAVFGAAQVPPLRRLLLGRIPQG
EEECCCCEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCC
EGPDERRRSKSWFTVDFVGEGDGRTVHTRVSGGDPGYDETAKMLAESALCLALDDNPPTS
CCCHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCC
GQVTTAQAMGDNLLTRLQAAGIRFETLD
CCEEEHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]