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The map label for this gene is pdxH

Identifier: 119714981

GI number: 119714981

Start: 782076

End: 782717

Strand: Direct

Name: pdxH

Synonym: Noca_0734

Alternate gene names: 119714981

Gene position: 782076-782717 (Clockwise)

Preceding gene: 119714979

Following gene: 119714982

Centisome position: 15.69

GC content: 73.21

Gene sequence:

>642_bases
ATGGGACACCTCGATCTCGCTGCTCTTCGTGAGGAGTATGCCCGGGCTGGTCTCGACGAGGCCGACCTCGCCCCCGACCC
GATCGCCATGTTCGACCGTTGGATGGGCGAGGCGCACGACGCGATCCGCCACGACGCGAACGCGATGGTGCTGAGCACCG
TCGGACCCGACCTGGCCCCCTCCTCGCGGATGCTGCTGCTCAAGGGCGTCGCCGAGGACGGGTTCGTCTTCTTCACCAAC
ACCGCCTCCCTCAAGGGCCACGAGCTCGCCGCGAACCCGCGCTGCTCGCTGCTCTTCCCGTGGCACCCCCTCGAGCGGCA
GGTGCGCGTCGACGGGGTCGCCGCCCCGCTCCCGCGCGCCGACGTCGAGGCGTACTTCGCCTCCCGGCCGCGGGCCTCCC
AGCTCGGTGCCTGGGCCTCGCACCAGTCGGAGGTGGTGTCGGGCCGCGCCGAGCTCGAGGCCGCCTACGCGGCTGCGGAG
GTCCGCTACCCCGACCAGGTCCCGACGCCGGAGGAGTGGGGCGGGTACGTCGTACGCCCCGAGGTCGTCGAGTTCTGGCA
GGGCCGCACCGGCCGCCTGCACGACCGCCTGCGCTACCGCCGTACCCCCGGCGGGTGGGTCACCGAGCGCCTCGCTCCCT
GA

Upstream 100 bases:

>100_bases
CTCCAGCCCGTGCTGCACCTCGGTCATGTGACTCCTTCGCTGGACTACGCGAGCAAGCGCCCGAGGCATTGTGCCCCGGG
CCGCGACTAGGGTCGAGGGC

Downstream 100 bases:

>100_bases
GCGGTAGTCCCTGACGGTTGTGCGGCGGATCCGCGGGCGAGACCGCGCAATCGTCAGGGACTATCGGAAATGAAGTTGTG
AGTGAGTGCTCACTCACTTA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MGHLDLAALREEYARAGLDEADLAPDPIAMFDRWMGEAHDAIRHDANAMVLSTVGPDLAPSSRMLLLKGVAEDGFVFFTN
TASLKGHELAANPRCSLLFPWHPLERQVRVDGVAAPLPRADVEAYFASRPRASQLGAWASHQSEVVSGRAELEAAYAAAE
VRYPDQVPTPEEWGGYVVRPEVVEFWQGRTGRLHDRLRYRRTPGGWVTERLAP

Sequences:

>Translated_213_residues
MGHLDLAALREEYARAGLDEADLAPDPIAMFDRWMGEAHDAIRHDANAMVLSTVGPDLAPSSRMLLLKGVAEDGFVFFTN
TASLKGHELAANPRCSLLFPWHPLERQVRVDGVAAPLPRADVEAYFASRPRASQLGAWASHQSEVVSGRAELEAAYAAAE
VRYPDQVPTPEEWGGYVVRPEVVEFWQGRTGRLHDRLRYRRTPGGWVTERLAP
>Mature_212_residues
GHLDLAALREEYARAGLDEADLAPDPIAMFDRWMGEAHDAIRHDANAMVLSTVGPDLAPSSRMLLLKGVAEDGFVFFTNT
ASLKGHELAANPRCSLLFPWHPLERQVRVDGVAAPLPRADVEAYFASRPRASQLGAWASHQSEVVSGRAELEAAYAAAEV
RYPDQVPTPEEWGGYVVRPEVVEFWQGRTGRLHDRLRYRRTPGGWVTERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=230, Percent_Identity=47.3913043478261, Blast_Score=189, Evalue=1e-48,
Organism=Escherichia coli, GI1787926, Length=209, Percent_Identity=47.3684210526316, Blast_Score=196, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17553712, Length=221, Percent_Identity=41.6289592760181, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=40.6698564593301, Blast_Score=159, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24644901, Length=229, Percent_Identity=41.4847161572052, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI45551845, Length=229, Percent_Identity=41.4847161572052, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24644903, Length=210, Percent_Identity=29.0476190476191, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_NOCSJ (A1SEM4)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_921946.1
- ProteinModelPortal:   A1SEM4
- SMR:   A1SEM4
- STRING:   A1SEM4
- GeneID:   4599619
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_0734
- eggNOG:   COG0259
- HOGENOM:   HBG327559
- OMA:   FTFFTNY
- PhylomeDB:   A1SEM4
- BioCyc:   NSP35761:NOCA_0734-MONOMER
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190
- TIGRFAMs:   TIGR00558

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 23611; Mature: 23480

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 63-63 BINDING 66-66 BINDING 68-68 BINDING 85-85 BINDING 125-125 BINDING 129-129 BINDING 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHLDLAALREEYARAGLDEADLAPDPIAMFDRWMGEAHDAIRHDANAMVLSTVGPDLAP
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
SSRMLLLKGVAEDGFVFFTNTASLKGHELAANPRCSLLFPWHPLERQVRVDGVAAPLPRA
CCCEEEEEECCCCCEEEEECCCCCCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCCCH
DVEAYFASRPRASQLGAWASHQSEVVSGRAELEAAYAAAEVRYPDQVPTPEEWGGYVVRP
HHHHHHHCCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHCCEEECH
EVVEFWQGRTGRLHDRLRYRRTPGGWVTERLAP
HHHHHHCCCCCCHHHHHHHCCCCCCCCHHCCCC
>Mature Secondary Structure 
GHLDLAALREEYARAGLDEADLAPDPIAMFDRWMGEAHDAIRHDANAMVLSTVGPDLAP
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
SSRMLLLKGVAEDGFVFFTNTASLKGHELAANPRCSLLFPWHPLERQVRVDGVAAPLPRA
CCCEEEEEECCCCCEEEEECCCCCCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCCCH
DVEAYFASRPRASQLGAWASHQSEVVSGRAELEAAYAAAEVRYPDQVPTPEEWGGYVVRP
HHHHHHHCCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHCCEEECH
EVVEFWQGRTGRLHDRLRYRRTPGGWVTERLAP
HHHHHHCCCCCCHHHHHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA