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The map label for this gene is amiC [H]

Identifier: 119714914

GI number: 119714914

Start: 707010

End: 708410

Strand: Direct

Name: amiC [H]

Synonym: Noca_0666

Alternate gene names: 119714914

Gene position: 707010-708410 (Clockwise)

Preceding gene: 119714913

Following gene: 119714916

Centisome position: 14.18

GC content: 74.8

Gene sequence:

>1401_bases
GTGACCCGAGTACACGCCTTCGGCGACGACGCCCTCGGCACCCTCGACGCGGTCGGGCTCGTCGAGGCCATCCAGGAGGG
CCGGGTGTCGATCCGCGAGGTGGTCGACGCCGCGATCGCCCGCACCGAGCGGCTCCAGCCCGAGCTCGGCGCGCTCGCCT
ACGTCGCCTACGACCGGGCCCGGGCCGAGGCCCGGGACCCGCGCGGCGGCTACTTCGCCGGGGTGCCGACCTTCGTCAAG
GACAACGTCGACGTCGCGCGGATGCCTACCCAGCAGGGCTGTGACGCCTACCGCGCCCGACCGGTCAAGCACGACGGTGA
CTTCGCCCGGATGTTCCTGGCCACCGGGCTGGTGCCGCTCGGCAAGACCCAGCTCTCCGAGTTCGGCTTCAGCCCCTCCG
CCGAGCACCCCCGCCTCGGGCCGGTGCGCTCGCCGTGGGACACCGCCCGCACCGCCGGCGCCTCGTCGGCGGGTACGGCG
GCGCTGGTGGCCGCCGGCGCCGTACCGATCGCCCACGGCAACGACGGCGGCGGCTCGATCCGGATCCCTGCGGCCGTCAA
CGGGCTGGTCGGGCTCAAGCCGACGCGCGACCGGCTGGCCCAGGACCGGCTGACCCGGCGGATGCCGGTGCGGATCGTGG
CCGACGGCGTGCTCACCCGCTCGGTGCGCGACACCGCGGCCTTCCTGCGCGAGGCCGAGCACGTGTACCGCGCCCTGTCG
CTGCCCCCGATCGGCGATGTCACCAGGCCGGGCCGGGCCCGGCTGCGGATCGCGGTGCACACCGGCGGGATCGGCCGCAC
CGCCTCCCCCGAGGTCGTCGACCTGACCCTCAAGACCGCCCGGCTCCTGGAGGAGCTGGGCCACGAGGTCGAGCAGGTCG
TGCACCCCGCGCCGGCGACGGTGCCCGAGGACTTCCTGCTCTACTGGTCGATGCTGGCGATGACGATCGTGGGTGCCGGC
CGCCGGCACCTCGGCACGTCGTGGGACCGCACCCGGCTCGACAACCTCACCCTCGGGCTGGACCGCCACTGCCGGCGGCG
CCTCCACCGGCTGCCCGGGGCGATCGCCCGGCTGCGCCGGCTGTCCCGGGTCTCCGCCGACTTCCACCGCCGCTACGACG
TCGCGCTCACCCCGACGCTCGCGCAGGCGACCCCGCTGATCGGGCACCTCGACCCGACCAACGACTTCGACACCGTGATG
GAGCGGATCCTCGAGTGGGTGGCGTTCACGCCATGGCAGAACGCGACCGGCGACCCCGCGGTGTCGCTGCCGCTCGCGAC
CACCTCGACCGGGATGCCGCAGGGGATGATGCTCTCCGCCGGAGCCGGCCGCGAGTCGACGCTCCTCGAGCTCGCCTACG
AGCTCGAGGAGGCGGCGCCCTGGCCGCGGATCACGGACTGA

Upstream 100 bases:

>100_bases
GAGTCGTCGGCTGCGCGGCACTGGCTCTCGACCACGTGCTGAGCCCGGTCGCCATCGACAGTCGGCTGGCCACCCAGGCC
TGACCGCTACCGTCTGCTCC

Downstream 100 bases:

>100_bases
CCGAGCGCGGTACGACGAGCAGCGCCTGCGCCGACCGGGCGACCAGGCCGCGCTCGTCGTACGTCGCGGAGGTGGCGACC
CCGACCGACCCGTCGGACAG

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTRVHAFGDDALGTLDAVGLVEAIQEGRVSIREVVDAAIARTERLQPELGALAYVAYDRARAEARDPRGGYFAGVPTFVK
DNVDVARMPTQQGCDAYRARPVKHDGDFARMFLATGLVPLGKTQLSEFGFSPSAEHPRLGPVRSPWDTARTAGASSAGTA
ALVAAGAVPIAHGNDGGGSIRIPAAVNGLVGLKPTRDRLAQDRLTRRMPVRIVADGVLTRSVRDTAAFLREAEHVYRALS
LPPIGDVTRPGRARLRIAVHTGGIGRTASPEVVDLTLKTARLLEELGHEVEQVVHPAPATVPEDFLLYWSMLAMTIVGAG
RRHLGTSWDRTRLDNLTLGLDRHCRRRLHRLPGAIARLRRLSRVSADFHRRYDVALTPTLAQATPLIGHLDPTNDFDTVM
ERILEWVAFTPWQNATGDPAVSLPLATTSTGMPQGMMLSAGAGRESTLLELAYELEEAAPWPRITD

Sequences:

>Translated_466_residues
MTRVHAFGDDALGTLDAVGLVEAIQEGRVSIREVVDAAIARTERLQPELGALAYVAYDRARAEARDPRGGYFAGVPTFVK
DNVDVARMPTQQGCDAYRARPVKHDGDFARMFLATGLVPLGKTQLSEFGFSPSAEHPRLGPVRSPWDTARTAGASSAGTA
ALVAAGAVPIAHGNDGGGSIRIPAAVNGLVGLKPTRDRLAQDRLTRRMPVRIVADGVLTRSVRDTAAFLREAEHVYRALS
LPPIGDVTRPGRARLRIAVHTGGIGRTASPEVVDLTLKTARLLEELGHEVEQVVHPAPATVPEDFLLYWSMLAMTIVGAG
RRHLGTSWDRTRLDNLTLGLDRHCRRRLHRLPGAIARLRRLSRVSADFHRRYDVALTPTLAQATPLIGHLDPTNDFDTVM
ERILEWVAFTPWQNATGDPAVSLPLATTSTGMPQGMMLSAGAGRESTLLELAYELEEAAPWPRITD
>Mature_465_residues
TRVHAFGDDALGTLDAVGLVEAIQEGRVSIREVVDAAIARTERLQPELGALAYVAYDRARAEARDPRGGYFAGVPTFVKD
NVDVARMPTQQGCDAYRARPVKHDGDFARMFLATGLVPLGKTQLSEFGFSPSAEHPRLGPVRSPWDTARTAGASSAGTAA
LVAAGAVPIAHGNDGGGSIRIPAAVNGLVGLKPTRDRLAQDRLTRRMPVRIVADGVLTRSVRDTAAFLREAEHVYRALSL
PPIGDVTRPGRARLRIAVHTGGIGRTASPEVVDLTLKTARLLEELGHEVEQVVHPAPATVPEDFLLYWSMLAMTIVGAGR
RHLGTSWDRTRLDNLTLGLDRHCRRRLHRLPGAIARLRRLSRVSADFHRRYDVALTPTLAQATPLIGHLDPTNDFDTVME
RILEWVAFTPWQNATGDPAVSLPLATTSTGMPQGMMLSAGAGRESTLLELAYELEEAAPWPRITD

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=508, Percent_Identity=25.5905511811024, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI195972892, Length=495, Percent_Identity=23.030303030303, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=294, Percent_Identity=28.9115646258503, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17538252, Length=325, Percent_Identity=26.7692307692308, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990152, Length=296, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17556276, Length=225, Percent_Identity=30.6666666666667, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17556278, Length=193, Percent_Identity=32.6424870466321, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538254, Length=309, Percent_Identity=23.3009708737864, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17537465, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319685, Length=123, Percent_Identity=40.650406504065, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648113, Length=502, Percent_Identity=26.4940239043825, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356731, Length=228, Percent_Identity=29.8245614035088, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644968, Length=196, Percent_Identity=30.1020408163265, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24652985, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922090, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652981, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652983, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550774, Length=194, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648435, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24648437, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 50506; Mature: 50375

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00019 ACTININ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVHAFGDDALGTLDAVGLVEAIQEGRVSIREVVDAAIARTERLQPELGALAYVAYDRA
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RAEARDPRGGYFAGVPTFVKDNVDVARMPTQQGCDAYRARPVKHDGDFARMFLATGLVPL
HHHCCCCCCCEECCCCHHHHCCCCCEECCCHHCCHHHHCCCCCCCCHHHHHHHHHCCCCC
GKTQLSEFGFSPSAEHPRLGPVRSPWDTARTAGASSAGTAALVAAGAVPIAHGNDGGGSI
CHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHCCEEEECCCCCCCEE
RIPAAVNGLVGLKPTRDRLAQDRLTRRMPVRIVADGVLTRSVRDTAAFLREAEHVYRALS
ECCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
LPPIGDVTRPGRARLRIAVHTGGIGRTASPEVVDLTLKTARLLEELGHEVEQVVHPAPAT
CCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
VPEDFLLYWSMLAMTIVGAGRRHLGTSWDRTRLDNLTLGLDRHCRRRLHRLPGAIARLRR
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHCCEEECHHHHHHHHHHHCCHHHHHHHH
LSRVSADFHRRYDVALTPTLAQATPLIGHLDPTNDFDTVMERILEWVAFTPWQNATGDPA
HHHHHHHHHHCCCEEECCHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VSLPLATTSTGMPQGMMLSAGAGRESTLLELAYELEEAAPWPRITD
EEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRVHAFGDDALGTLDAVGLVEAIQEGRVSIREVVDAAIARTERLQPELGALAYVAYDRA
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RAEARDPRGGYFAGVPTFVKDNVDVARMPTQQGCDAYRARPVKHDGDFARMFLATGLVPL
HHHCCCCCCCEECCCCHHHHCCCCCEECCCHHCCHHHHCCCCCCCCHHHHHHHHHCCCCC
GKTQLSEFGFSPSAEHPRLGPVRSPWDTARTAGASSAGTAALVAAGAVPIAHGNDGGGSI
CHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHCCEEEECCCCCCCEE
RIPAAVNGLVGLKPTRDRLAQDRLTRRMPVRIVADGVLTRSVRDTAAFLREAEHVYRALS
ECCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
LPPIGDVTRPGRARLRIAVHTGGIGRTASPEVVDLTLKTARLLEELGHEVEQVVHPAPAT
CCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
VPEDFLLYWSMLAMTIVGAGRRHLGTSWDRTRLDNLTLGLDRHCRRRLHRLPGAIARLRR
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHCCEEECHHHHHHHHHHHCCHHHHHHHH
LSRVSADFHRRYDVALTPTLAQATPLIGHLDPTNDFDTVMERILEWVAFTPWQNATGDPA
HHHHHHHHHHCCCEEECCHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VSLPLATTSTGMPQGMMLSAGAGRESTLLELAYELEEAAPWPRITD
EEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]