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The map label for this gene is gltC [H]

Identifier: 119714874

GI number: 119714874

Start: 658209

End: 659132

Strand: Direct

Name: gltC [H]

Synonym: Noca_0620

Alternate gene names: 119714874

Gene position: 658209-659132 (Clockwise)

Preceding gene: 119714871

Following gene: 119714875

Centisome position: 13.2

GC content: 65.37

Gene sequence:

>924_bases
ATGCGGTACGTCCTGGCAGTCGCCGACGCCCGGAACTTCACCAGGGCCGCGGAGCAGTGCTTCGTCGTCCAGTCAGCACT
CAGCCAGCGCATCGCCAACCTTGAGCGCGAGCTCGGCGTAGCGCTGTTCGCCCGCACCAGTCGCCGTGTCGAGCTGACCG
CGGCTGGCCAGGCGTTCATCCCACCAGCGCGTCAGTGTCTTGAGGCTGCCGACCGGGCCGCAGCCGAAGCTGCTGCGGCC
GTAGGGCAAGTGCGGGGTCGGCTCACCATCGGCGTGATCCCAAACGTGGCAGCCGTCGACCTGCCCGATGTCCTACGGCG
GGTCCGGGAGAAGTACCTTGCGGTTCGCATCGAGTTGCGGGTCGGCGCAAGTGACTGGCTGGCAGAACAGGTTGTCGCAG
GGAATCTCGATGTTGCATTTCTGGGCCTCCCCGAGAACCAGAAGCCCGTCGGCGTGAGCTTCCGCGCATTGGCCAGCGAT
CGCCATGTTGCGGTCCTACCGGTCGACCACCATCTCGCGGGGCGCGCCGAGGTCGGCCTAGCGGACCTGTCCGACGAAGC
GTTCGCGGACTTTCCCTACGGTTCACCGGGCCGCGCCCAAGGAGATTATGCCTTTGCCTCCGCAGAGATCCGACGAGACG
TCGCATACGAGGTCGTTTCCGCCGACCTGATGCTGGATCTCGTCAGGCATGGGCTTGCGGTGGCATTGCTGCCATCGATG
TCCGTAAACCCCATGCCCGAGCTGGCCATCGTCTCAGTTACTGACGGCCCTGGCCGCGTCGAGTACCTCGCTTGGAGCGA
CTTCAATCCCAGCCCGGCGACCCGTGCATTTCTCGACATTCTAGCGGACGAGGCAAGCCCGGGAACCGGGCACGACGTGC
ATCGTTCCGCTTTACCAGCGATCCGCGGATCCGATCCGACCTGA

Upstream 100 bases:

>100_bases
CACTCACTCTGCGAGTCTTGGCCCTGGTCATCAATCAGTCCAACGCAGGGTTGCGATGGAACCGATCGTTCCTCATGATT
GATGGGTGGATCTTCAACAG

Downstream 100 bases:

>100_bases
CTCATCTTTCGTTCGATTCGAGATCACCGACTTGTCCGCGACACGAGGCAGAGGGCCCGGAGCAGTTGCCAGGCGCGGAG
AGATCCTCCAGGTGGGTTGC

Product: substrate-binding protein LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRYVLAVADARNFTRAAEQCFVVQSALSQRIANLERELGVALFARTSRRVELTAAGQAFIPPARQCLEAADRAAAEAAAA
VGQVRGRLTIGVIPNVAAVDLPDVLRRVREKYLAVRIELRVGASDWLAEQVVAGNLDVAFLGLPENQKPVGVSFRALASD
RHVAVLPVDHHLAGRAEVGLADLSDEAFADFPYGSPGRAQGDYAFASAEIRRDVAYEVVSADLMLDLVRHGLAVALLPSM
SVNPMPELAIVSVTDGPGRVEYLAWSDFNPSPATRAFLDILADEASPGTGHDVHRSALPAIRGSDPT

Sequences:

>Translated_307_residues
MRYVLAVADARNFTRAAEQCFVVQSALSQRIANLERELGVALFARTSRRVELTAAGQAFIPPARQCLEAADRAAAEAAAA
VGQVRGRLTIGVIPNVAAVDLPDVLRRVREKYLAVRIELRVGASDWLAEQVVAGNLDVAFLGLPENQKPVGVSFRALASD
RHVAVLPVDHHLAGRAEVGLADLSDEAFADFPYGSPGRAQGDYAFASAEIRRDVAYEVVSADLMLDLVRHGLAVALLPSM
SVNPMPELAIVSVTDGPGRVEYLAWSDFNPSPATRAFLDILADEASPGTGHDVHRSALPAIRGSDPT
>Mature_307_residues
MRYVLAVADARNFTRAAEQCFVVQSALSQRIANLERELGVALFARTSRRVELTAAGQAFIPPARQCLEAADRAAAEAAAA
VGQVRGRLTIGVIPNVAAVDLPDVLRRVREKYLAVRIELRVGASDWLAEQVVAGNLDVAFLGLPENQKPVGVSFRALASD
RHVAVLPVDHHLAGRAEVGLADLSDEAFADFPYGSPGRAQGDYAFASAEIRRDVAYEVVSADLMLDLVRHGLAVALLPSM
SVNPMPELAIVSVTDGPGRVEYLAWSDFNPSPATRAFLDILADEASPGTGHDVHRSALPAIRGSDPT

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=32.404181184669, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787530, Length=263, Percent_Identity=29.277566539924, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=31.3008130081301, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI145693105, Length=254, Percent_Identity=25.9842519685039, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=29.7520661157025, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788296, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787806, Length=257, Percent_Identity=28.7937743190661, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790208, Length=249, Percent_Identity=30.5220883534137, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=24.5967741935484, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=30.0813008130081, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367136, Length=242, Percent_Identity=27.6859504132231, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788626, Length=138, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32779; Mature: 32779

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVLAVADARNFTRAAEQCFVVQSALSQRIANLERELGVALFARTSRRVELTAAGQAFI
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCC
PPARQCLEAADRAAAEAAAAVGQVRGRLTIGVIPNVAAVDLPDVLRRVREKYLAVRIELR
CHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECHHHHHHHHHHHHEEEEEEEE
VGASDWLAEQVVAGNLDVAFLGLPENQKPVGVSFRALASDRHVAVLPVDHHLAGRAEVGL
ECCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
ADLSDEAFADFPYGSPGRAQGDYAFASAEIRRDVAYEVVSADLMLDLVRHGLAVALLPSM
CCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SVNPMPELAIVSVTDGPGRVEYLAWSDFNPSPATRAFLDILADEASPGTGHDVHRSALPA
CCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCC
IRGSDPT
CCCCCCC
>Mature Secondary Structure
MRYVLAVADARNFTRAAEQCFVVQSALSQRIANLERELGVALFARTSRRVELTAAGQAFI
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCC
PPARQCLEAADRAAAEAAAAVGQVRGRLTIGVIPNVAAVDLPDVLRRVREKYLAVRIELR
CHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECHHHHHHHHHHHHEEEEEEEE
VGASDWLAEQVVAGNLDVAFLGLPENQKPVGVSFRALASDRHVAVLPVDHHLAGRAEVGL
ECCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
ADLSDEAFADFPYGSPGRAQGDYAFASAEIRRDVAYEVVSADLMLDLVRHGLAVALLPSM
CCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SVNPMPELAIVSVTDGPGRVEYLAWSDFNPSPATRAFLDILADEASPGTGHDVHRSALPA
CCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCC
IRGSDPT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]