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The map label for this gene is rbsK [H]

Identifier: 119714809

GI number: 119714809

Start: 579216

End: 580130

Strand: Reverse

Name: rbsK [H]

Synonym: Noca_0545

Alternate gene names: 119714809

Gene position: 580130-579216 (Counterclockwise)

Preceding gene: 119714813

Following gene: 119714808

Centisome position: 11.64

GC content: 75.3

Gene sequence:

>915_bases
ATGCGTATCGCGGTGGTGGGGAGCTACGGGGTCGGCATGACCATGCGGATGCCGCGGCTGCCGGTGGCCGGCGAGACGCT
GCTCGGTGGCGAGTACCGGTCCGGCCACGGCGGCAAGGGCTCCAACCAGGCGGTCGCGGCCAGCCGGCTCGGCGCGGAGG
TCACCCTGCTCACCGCGGTCGGCGGCGACGCCATCGGGCGGGCCGCCCGCGATATGTGGGCCGCGGAGGGCGTCGACGCG
ACGGCGACGATCACCGCACCCGCAGCGACCATGGTCGGGATGATCCTCGTCGAGCCCAGCGGGGAGAACCGGATCGTGAT
CGCCACCGGCGCGCTGGACCACCTCACCCCCCGGCACGTGCAGGACTTCGCACCGCAGCTCGCGGCCGCTGACATCGCGG
TCGTCTCGCTCGAGATCCCGATGGCGACGGCCGTCGCCGCCCTCCGGGCCGCGCACGAGGCTGGCACCCGCACGCTGCTC
AATCCCGCCCCGGCCCAACCGATCCCCGACGAAGCCTGGTCGAACGTCGACCTGCTCACTCCGAACCGCACCGAGGCGGC
GATCCTGCTCGGGCTGCCTCCCGACGCGGCCGGACCGGCCGAGGAGCTGGCCCGGCAGCTCCACGAGCGCGGCGGCGCCA
CGATCGTGCTGACCCTGGGCGCCGAGGGCGCCCTGATCTGTGACGCCGGCGGCCTCACCCCGGTGGCGGCCGTCCCTCCC
GCCGAGGTGGTCGACACCACCGGTGCCGGCGACGCCTTCACCGCCGCCCTGGCCGTCGAGCTGGCCGGCGGCGGCTCGGT
CCCGGGCGCCGTGGCGTTCGCAGCCCGGGTCGGCGCCTTCGCCGTCGCGCATCACGAGGTCTTCCCCGGTCTGCCGCGCC
GGACCGACCTCGACACCGAACCCGACCTCACCTGA

Upstream 100 bases:

>100_bases
CTACCGCTGAATCGCCGCGCCCTCCGCGCAGCACAGGCGAAGGTGGGCGCGCCTGGCGCCATATGTCTATAGTTGTCCAT
AGACACATGGGAGGTTCAGG

Downstream 100 bases:

>100_bases
CCGCAGGCCGGACCGCCCGCGCCCCAAGTTCCCCGGAAGGACACCGATGACCGAATACGCCTCGCTCACGCCAGCCGAGC
TGGCCCCCTACATCCAGCAC

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRIAVVGSYGVGMTMRMPRLPVAGETLLGGEYRSGHGGKGSNQAVAASRLGAEVTLLTAVGGDAIGRAARDMWAAEGVDA
TATITAPAATMVGMILVEPSGENRIVIATGALDHLTPRHVQDFAPQLAAADIAVVSLEIPMATAVAALRAAHEAGTRTLL
NPAPAQPIPDEAWSNVDLLTPNRTEAAILLGLPPDAAGPAEELARQLHERGGATIVLTLGAEGALICDAGGLTPVAAVPP
AEVVDTTGAGDAFTAALAVELAGGGSVPGAVAFAARVGAFAVAHHEVFPGLPRRTDLDTEPDLT

Sequences:

>Translated_304_residues
MRIAVVGSYGVGMTMRMPRLPVAGETLLGGEYRSGHGGKGSNQAVAASRLGAEVTLLTAVGGDAIGRAARDMWAAEGVDA
TATITAPAATMVGMILVEPSGENRIVIATGALDHLTPRHVQDFAPQLAAADIAVVSLEIPMATAVAALRAAHEAGTRTLL
NPAPAQPIPDEAWSNVDLLTPNRTEAAILLGLPPDAAGPAEELARQLHERGGATIVLTLGAEGALICDAGGLTPVAAVPP
AEVVDTTGAGDAFTAALAVELAGGGSVPGAVAFAARVGAFAVAHHEVFPGLPRRTDLDTEPDLT
>Mature_304_residues
MRIAVVGSYGVGMTMRMPRLPVAGETLLGGEYRSGHGGKGSNQAVAASRLGAEVTLLTAVGGDAIGRAARDMWAAEGVDA
TATITAPAATMVGMILVEPSGENRIVIATGALDHLTPRHVQDFAPQLAAADIAVVSLEIPMATAVAALRAAHEAGTRTLL
NPAPAQPIPDEAWSNVDLLTPNRTEAAILLGLPPDAAGPAEELARQLHERGGATIVLTLGAEGALICDAGGLTPVAAVPP
AEVVDTTGAGDAFTAALAVELAGGGSVPGAVAFAARVGAFAVAHHEVFPGLPRRTDLDTEPDLT

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=260, Percent_Identity=38.0769230769231, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=36.4548494983278, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87081971, Length=259, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788017, Length=259, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788491, Length=268, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=288, Percent_Identity=32.6388888888889, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=27.4096385542169, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20128807, Length=269, Percent_Identity=35.6877323420074, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24583886, Length=272, Percent_Identity=29.0441176470588, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30561; Mature: 30561

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVVGSYGVGMTMRMPRLPVAGETLLGGEYRSGHGGKGSNQAVAASRLGAEVTLLTAV
CEEEEEECCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEC
GGDAIGRAARDMWAAEGVDATATITAPAATMVGMILVEPSGENRIVIATGALDHLTPRHV
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHEEEEEEECCCCCCEEEEEECCHHHCCHHHH
QDFAPQLAAADIAVVSLEIPMATAVAALRAAHEAGTRTLLNPAPAQPIPDEAWSNVDLLT
HHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHCCCEEEC
PNRTEAAILLGLPPDAAGPAEELARQLHERGGATIVLTLGAEGALICDAGGLTPVAAVPP
CCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCC
AEVVDTTGAGDAFTAALAVELAGGGSVPGAVAFAARVGAFAVAHHEVFPGLPRRTDLDTE
HHHHCCCCCCHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHEEHHHHCCCCCCCCCCCCC
PDLT
CCCC
>Mature Secondary Structure
MRIAVVGSYGVGMTMRMPRLPVAGETLLGGEYRSGHGGKGSNQAVAASRLGAEVTLLTAV
CEEEEEECCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEC
GGDAIGRAARDMWAAEGVDATATITAPAATMVGMILVEPSGENRIVIATGALDHLTPRHV
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHEEEEEEECCCCCCEEEEEECCHHHCCHHHH
QDFAPQLAAADIAVVSLEIPMATAVAALRAAHEAGTRTLLNPAPAQPIPDEAWSNVDLLT
HHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHCCCEEEC
PNRTEAAILLGLPPDAAGPAEELARQLHERGGATIVLTLGAEGALICDAGGLTPVAAVPP
CCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCC
AEVVDTTGAGDAFTAALAVELAGGGSVPGAVAFAARVGAFAVAHHEVFPGLPRRTDLDTE
HHHHCCCCCCHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHEEHHHHCCCCCCCCCCCCC
PDLT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]