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The map label for this gene is nuoC

Identifier: 119714786

GI number: 119714786

Start: 552083

End: 552835

Strand: Direct

Name: nuoC

Synonym: Noca_0522

Alternate gene names: 119714786

Gene position: 552083-552835 (Clockwise)

Preceding gene: 119714785

Following gene: 119714787

Centisome position: 11.07

GC content: 71.18

Gene sequence:

>753_bases
GTGAGCGACGACTCCAGCGACGTGAAGCCGGGCCCGAAGGGACCCGAGCAGCCGGCCGTCGAGCAATCCCCGGAGAACGT
CCCGGCGCCCACGGGAGAGGTCCATCAGGTCGGCGCGCGCCACGGCATGTTCGGCGTGCGCGGCACCGGTGACACCAGCG
GGTACGGCGGCCTCAACCAGGCGATCGTGCTGCCCGGCGACGCCCAGCGGCCCTATGGCGGCTGGTTCGACGAGGTCGCG
GACGGCCTGGCCGCAGCGACCCGCGAGGCCGGCCTCGAGATCGCGGCTCCGCGGGTGGTGATCCACCGGGGTGAGATCAC
CTTCCACCTGCGCCGCGAGGACCTGCTGCCCGTGGCACAGGTGCTGCGTGACGACGAACGGCTGCGCTTCGAGTTCTGCG
CCGGCGTCAGCGGGGTGCACTACCCCGACGAGACCGGTCGTGAGCTGCACGCGGTCTACCACCTGCTCTCGATGACCCAC
AACCGTCGGATCCGCCTCGAGGTCGCCGTCCCGGACGCCGACCCGCACATCCCCTCGATCGTGCCGGTCTACCCGACCAA
CGACTGGCACGAGCGGGAGACCTACGACATGTTCGGGATCATCTTCGACGGCCACCCGGCGCTCACCCGCATCCTGATGC
CGGACGACTGGCCCGGCCACCCGCAGCGCAAGGACTACCCGCTCGGGGGCGTTCCCGTGGAGTACAAGGGCGGCACGGTC
CCCCCGCCCGACCAGCGGAGGAGCTACAACTGA

Upstream 100 bases:

>100_bases
AGCACACCAAGATGGGCGCCCACCGCGCGGCCGAGATCGAGGAGCTCGAGACGGCGGCGCTGCGCGCGCTCCCCACCTCC
GAGATGAAGGGCCAGCTGCG

Downstream 100 bases:

>100_bases
TGGCCGACCAGGATCTCTACTCCGGCTCCAGCGAGACGACCGAGGGCCGGGTCTTCACCGTCACCGGGCAGGACTGGGAC
TCGATCGCCGAGGGCCTGGC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSDDSSDVKPGPKGPEQPAVEQSPENVPAPTGEVHQVGARHGMFGVRGTGDTSGYGGLNQAIVLPGDAQRPYGGWFDEVA
DGLAAATREAGLEIAAPRVVIHRGEITFHLRREDLLPVAQVLRDDERLRFEFCAGVSGVHYPDETGRELHAVYHLLSMTH
NRRIRLEVAVPDADPHIPSIVPVYPTNDWHERETYDMFGIIFDGHPALTRILMPDDWPGHPQRKDYPLGGVPVEYKGGTV
PPPDQRRSYN

Sequences:

>Translated_250_residues
MSDDSSDVKPGPKGPEQPAVEQSPENVPAPTGEVHQVGARHGMFGVRGTGDTSGYGGLNQAIVLPGDAQRPYGGWFDEVA
DGLAAATREAGLEIAAPRVVIHRGEITFHLRREDLLPVAQVLRDDERLRFEFCAGVSGVHYPDETGRELHAVYHLLSMTH
NRRIRLEVAVPDADPHIPSIVPVYPTNDWHERETYDMFGIIFDGHPALTRILMPDDWPGHPQRKDYPLGGVPVEYKGGTV
PPPDQRRSYN
>Mature_249_residues
SDDSSDVKPGPKGPEQPAVEQSPENVPAPTGEVHQVGARHGMFGVRGTGDTSGYGGLNQAIVLPGDAQRPYGGWFDEVAD
GLAAATREAGLEIAAPRVVIHRGEITFHLRREDLLPVAQVLRDDERLRFEFCAGVSGVHYPDETGRELHAVYHLLSMTHN
RRIRLEVAVPDADPHIPSIVPVYPTNDWHERETYDMFGIIFDGHPALTRILMPDDWPGHPQRKDYPLGGVPVEYKGGTVP
PPDQRRSYN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=116, Percent_Identity=40.5172413793103, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI145693162, Length=132, Percent_Identity=40.9090909090909, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990788, Length=116, Percent_Identity=38.7931034482759, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32563621, Length=116, Percent_Identity=38.7931034482759, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24656494, Length=118, Percent_Identity=38.9830508474576, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_NOCSJ (A1SE29)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_921751.1
- ProteinModelPortal:   A1SE29
- SMR:   A1SE29
- STRING:   A1SE29
- GeneID:   4596442
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_0522
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VYPTNDW
- ProtClustDB:   PRK07785
- BioCyc:   NSP35761:NOCA_0522-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 27573; Mature: 27442

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDSSDVKPGPKGPEQPAVEQSPENVPAPTGEVHQVGARHGMFGVRGTGDTSGYGGLNQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCC
AIVLPGDAQRPYGGWFDEVADGLAAATREAGLEIAAPRVVIHRGEITFHLRREDLLPVAQ
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCEEEEEECCEEEEECCCCCHHHHH
VLRDDERLRFEFCAGVSGVHYPDETGRELHAVYHLLSMTHNRRIRLEVAVPDADPHIPSI
HHCCCCCEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCE
VPVYPTNDWHERETYDMFGIIFDGHPALTRILMPDDWPGHPQRKDYPLGGVPVEYKGGTV
EEECCCCCCCCCCCEEEEEEEECCCHHHEEEECCCCCCCCCCCCCCCCCCEEEEECCCCC
PPPDQRRSYN
CCCCCCCCCC
>Mature Secondary Structure 
SDDSSDVKPGPKGPEQPAVEQSPENVPAPTGEVHQVGARHGMFGVRGTGDTSGYGGLNQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCC
AIVLPGDAQRPYGGWFDEVADGLAAATREAGLEIAAPRVVIHRGEITFHLRREDLLPVAQ
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCEEEEEECCEEEEECCCCCHHHHH
VLRDDERLRFEFCAGVSGVHYPDETGRELHAVYHLLSMTHNRRIRLEVAVPDADPHIPSI
HHCCCCCEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCE
VPVYPTNDWHERETYDMFGIIFDGHPALTRILMPDDWPGHPQRKDYPLGGVPVEYKGGTV
EEECCCCCCCCCCCEEEEEEEECCCHHHEEEECCCCCCCCCCCCCCCCCCEEEEECCCCC
PPPDQRRSYN
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA