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The map label for this gene is acuC [H]

Identifier: 119714747

GI number: 119714747

Start: 513595

End: 514779

Strand: Direct

Name: acuC [H]

Synonym: Noca_0483

Alternate gene names: 119714747

Gene position: 513595-514779 (Clockwise)

Preceding gene: 119714745

Following gene: 119714748

Centisome position: 10.3

GC content: 73.25

Gene sequence:

>1185_bases
ATGCCCGCCTGCCAGGGACCGGCGACCGTCGTGTTCGACCCCAGCCTGACCGCGTACGACTTCGGCCCGACCCATCCGAT
GTCCCCGCTGCGGGTCGACCTGACCATCCGGCTGGCCGAGGAGCTCGGCGTCCTGGCCGGGCTGCGGCGGGTCGACGCCC
CCGTGGCCACCGACGAGGTGATCGCGACGGTGCACCGGCCCGCGCTCATCGAGGCGGTACGCCGTGCCGGCACCATGCCC
GGCATCCTCGACGAGGCCCACGGGCTGGGCACCGACGACAACCCGACCTTCCCGGACATGCACCACGCGGCCGCGCACAT
CGTCGGTGCGACCGTCGAGGCCGCCCGTCAGGTGTGGTCGGGGGAGTCCCTCCACGCCGTGAACATCAGCGGCGGCCTCC
ACCACGCGATGCCGGAGCGGGCCAGCGGCTTCTGCATCTACAACGACGTCGCGGTCGGCATCCAGCACCTCCTCGACAGC
GGGGCGAAGCGGGTGGCCTACGTGGACGTCGACGTCCATCACGGCGACGGGGTGGAGAAGGTGTTCTGGGACGACCCGCG
GGTGCTGACGATCTCGCTGCACGAGACGGGCCAGATGCTGTTCCCCGGCACGGGGTTCCCGACCGACGCCGGCGGCCCGG
CGGCGCGGGGTACGGCCGTCAACGTGGCGCTGCCCCCCGGCACCGGCGACGGCGGCTGGCTGCGCGCCTACCACGCCGTG
GTGCCCCCGCTGGTGCGCGAGTTCGCGCCCGACGTCCTGGTCACCCAGCACGGCTGCGACTCCCACATCGAGGACCCGCT
GGCGCACCTGATGCTCTCCGTGGATGGACAGCGGGCGGCCTACCTGGCCCTCCACGAGCTGGCCCACGAGGTCTGTGGTG
GGCGGTGGGTCGCCACCGGCGGCGGCGGATACGCCCTGGTCGAGGTGGTCCCGCGGGCCTGGACCCACCTGCTGGCGATC
GTGGCCGGCCGGCCGCTCGACCCGGCCACCGAGACCCCGGAGGGGTGGCGCAGGCACGTGCAGACCACGTTGGACCAGGT
CGCACCCCACCGGATGACCGACGGCCGGACCCCGGCGTACCGGGACTGGATCGACGGCTACGACCCCGAGATCTGGCTGG
ACCGGGCGATCCACAGCACCCGGATGGAGGTCTTCCCGCTGCACGGGCTCGACCCGTTTCCCTGA

Upstream 100 bases:

>100_bases
GCTTCGTGCGCGGTCCGCCGTCAGGCGAGCCACCACTGGGTGGTACGGAACGTGGAACAGGACGTCAGCACCGGACCAGA
CTACCGGTAGCGTCCGTCAC

Downstream 100 bases:

>100_bases
TCCCGGGTCGCGCCGGGGTGGCGCCGGCCGGGGGTGGACGCCGGCTTCGCGCAAGTCGACACGCCGACACCACTCGGGCG
ACTTTTAGCAACCCCTTCCC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPACQGPATVVFDPSLTAYDFGPTHPMSPLRVDLTIRLAEELGVLAGLRRVDAPVATDEVIATVHRPALIEAVRRAGTMP
GILDEAHGLGTDDNPTFPDMHHAAAHIVGATVEAARQVWSGESLHAVNISGGLHHAMPERASGFCIYNDVAVGIQHLLDS
GAKRVAYVDVDVHHGDGVEKVFWDDPRVLTISLHETGQMLFPGTGFPTDAGGPAARGTAVNVALPPGTGDGGWLRAYHAV
VPPLVREFAPDVLVTQHGCDSHIEDPLAHLMLSVDGQRAAYLALHELAHEVCGGRWVATGGGGYALVEVVPRAWTHLLAI
VAGRPLDPATETPEGWRRHVQTTLDQVAPHRMTDGRTPAYRDWIDGYDPEIWLDRAIHSTRMEVFPLHGLDPFP

Sequences:

>Translated_394_residues
MPACQGPATVVFDPSLTAYDFGPTHPMSPLRVDLTIRLAEELGVLAGLRRVDAPVATDEVIATVHRPALIEAVRRAGTMP
GILDEAHGLGTDDNPTFPDMHHAAAHIVGATVEAARQVWSGESLHAVNISGGLHHAMPERASGFCIYNDVAVGIQHLLDS
GAKRVAYVDVDVHHGDGVEKVFWDDPRVLTISLHETGQMLFPGTGFPTDAGGPAARGTAVNVALPPGTGDGGWLRAYHAV
VPPLVREFAPDVLVTQHGCDSHIEDPLAHLMLSVDGQRAAYLALHELAHEVCGGRWVATGGGGYALVEVVPRAWTHLLAI
VAGRPLDPATETPEGWRRHVQTTLDQVAPHRMTDGRTPAYRDWIDGYDPEIWLDRAIHSTRMEVFPLHGLDPFP
>Mature_393_residues
PACQGPATVVFDPSLTAYDFGPTHPMSPLRVDLTIRLAEELGVLAGLRRVDAPVATDEVIATVHRPALIEAVRRAGTMPG
ILDEAHGLGTDDNPTFPDMHHAAAHIVGATVEAARQVWSGESLHAVNISGGLHHAMPERASGFCIYNDVAVGIQHLLDSG
AKRVAYVDVDVHHGDGVEKVFWDDPRVLTISLHETGQMLFPGTGFPTDAGGPAARGTAVNVALPPGTGDGGWLRAYHAVV
PPLVREFAPDVLVTQHGCDSHIEDPLAHLMLSVDGQRAAYLALHELAHEVCGGRWVATGGGGYALVEVVPRAWTHLLAIV
AGRPLDPATETPEGWRRHVQTTLDQVAPHRMTDGRTPAYRDWIDGYDPEIWLDRAIHSTRMEVFPLHGLDPFP

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=360, Percent_Identity=29.7222222222222, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI8923769, Length=312, Percent_Identity=33.6538461538462, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI13128860, Length=370, Percent_Identity=28.9189189189189, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI293336691, Length=356, Percent_Identity=28.3707865168539, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI262073092, Length=219, Percent_Identity=36.5296803652968, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI17158039, Length=296, Percent_Identity=30.7432432432432, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI262073088, Length=213, Percent_Identity=33.8028169014084, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI30795204, Length=292, Percent_Identity=30.8219178082192, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI30795202, Length=292, Percent_Identity=30.8219178082192, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI13128864, Length=317, Percent_Identity=30.5993690851735, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI169234807, Length=262, Percent_Identity=32.824427480916, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI148539870, Length=260, Percent_Identity=32.3076923076923, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI153085395, Length=334, Percent_Identity=29.6407185628743, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI62750347, Length=335, Percent_Identity=31.6417910447761, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI62750349, Length=335, Percent_Identity=31.6417910447761, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI20070354, Length=288, Percent_Identity=28.8194444444444, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI217272877, Length=302, Percent_Identity=25.1655629139073, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI209862883, Length=285, Percent_Identity=25.6140350877193, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI226529806, Length=229, Percent_Identity=29.6943231441048, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508561, Length=327, Percent_Identity=31.4984709480122, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17534739, Length=314, Percent_Identity=31.8471337579618, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17561978, Length=320, Percent_Identity=30.625, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193206283, Length=300, Percent_Identity=29.3333333333333, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17540332, Length=300, Percent_Identity=29.3333333333333, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17540334, Length=300, Percent_Identity=29.3333333333333, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI193209491, Length=267, Percent_Identity=31.4606741573034, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25154020, Length=311, Percent_Identity=23.1511254019293, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=311, Percent_Identity=22.8295819935691, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537347, Length=282, Percent_Identity=25.177304964539, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321244, Length=315, Percent_Identity=31.4285714285714, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323999, Length=366, Percent_Identity=30.6010928961749, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325325, Length=235, Percent_Identity=32.3404255319149, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324307, Length=337, Percent_Identity=27.5964391691395, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644244, Length=333, Percent_Identity=30.6306306306306, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24657891, Length=360, Percent_Identity=29.7222222222222, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24642146, Length=310, Percent_Identity=30.6451612903226, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281360899, Length=310, Percent_Identity=30.6451612903226, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24642144, Length=310, Percent_Identity=30.6451612903226, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24642142, Length=310, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360801, Length=313, Percent_Identity=28.7539936102236, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360799, Length=312, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641720, Length=313, Percent_Identity=28.7539936102236, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24649807, Length=154, Percent_Identity=30.5194805194805, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 42375; Mature: 42244

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPACQGPATVVFDPSLTAYDFGPTHPMSPLRVDLTIRLAEELGVLAGLRRVDAPVATDEV
CCCCCCCEEEEECCCCEEEECCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCHHHH
IATVHRPALIEAVRRAGTMPGILDEAHGLGTDDNPTFPDMHHAAAHIVGATVEAARQVWS
HHHHCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GESLHAVNISGGLHHAMPERASGFCIYNDVAVGIQHLLDSGAKRVAYVDVDVHHGDGVEK
CCCEEEEEECCCHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCE
VFWDDPRVLTISLHETGQMLFPGTGFPTDAGGPAARGTAVNVALPPGTGDGGWLRAYHAV
EECCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
VPPLVREFAPDVLVTQHGCDSHIEDPLAHLMLSVDGQRAAYLALHELAHEVCGGRWVATG
HHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEC
GGGYALVEVVPRAWTHLLAIVAGRPLDPATETPEGWRRHVQTTLDQVAPHRMTDGRTPAY
CCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
RDWIDGYDPEIWLDRAIHSTRMEVFPLHGLDPFP
HHHHCCCCCHHHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure 
PACQGPATVVFDPSLTAYDFGPTHPMSPLRVDLTIRLAEELGVLAGLRRVDAPVATDEV
CCCCCCEEEEECCCCEEEECCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCHHHH
IATVHRPALIEAVRRAGTMPGILDEAHGLGTDDNPTFPDMHHAAAHIVGATVEAARQVWS
HHHHCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GESLHAVNISGGLHHAMPERASGFCIYNDVAVGIQHLLDSGAKRVAYVDVDVHHGDGVEK
CCCEEEEEECCCHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCE
VFWDDPRVLTISLHETGQMLFPGTGFPTDAGGPAARGTAVNVALPPGTGDGGWLRAYHAV
EECCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
VPPLVREFAPDVLVTQHGCDSHIEDPLAHLMLSVDGQRAAYLALHELAHEVCGGRWVATG
HHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEC
GGGYALVEVVPRAWTHLLAIVAGRPLDPATETPEGWRRHVQTTLDQVAPHRMTDGRTPAY
CCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
RDWIDGYDPEIWLDRAIHSTRMEVFPLHGLDPFP
HHHHCCCCCHHHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]