Click here to switch to the map view.

The map label for this gene is rnhA [H]

Identifier: 119714682

GI number: 119714682

Start: 450212

End: 450643

Strand: Direct

Name: rnhA [H]

Synonym: Noca_0418

Alternate gene names: 119714682

Gene position: 450212-450643 (Clockwise)

Preceding gene: 119714680

Following gene: 119714683

Centisome position: 9.03

GC content: 72.92

Gene sequence:

>432_bases
ATGCCGGTCCCCGAGGGGGCCCGCGAGGTGTTCACGGACGGCGCCTGCTCCGGCAACCCGGGCCCCGGCGGCTGGGCCTG
GGCCCTGGACACCGCCGTCTACGCCTCTGGCCGCGAAGCGCCCTCGACCAACCAGCGGATGGAGATCCGAGCGGCGCTGG
AGGCGGTGCGGTCCCTCGACGGGCCGCTGCTGGTGGTGAGCGACTCGACGTACGTCGTCCACTGCTTCCGCGACCTGTGG
TGGCAGGGCTGGCTGGACCGGGACTGGGTGAGCTCGGCCCGCAAGCCGGTCGCCAACCGGGACCTCTGGGAGCCGCTGGT
CGGCCTGGTCCAGGACCGTGGTGACGTCGCGTTCGCCTGGGTGAAAGGCCACTCGGGCCACGTCATGAACGACTTCGTGG
ACCGGCTCGCCGTCGCGGCGACACGGGCGTGA

Upstream 100 bases:

>100_bases
CGGCTCGGTTCCCATGACCGATGACGGTAGCCAACCGCCGCTGTGCGAGGGTGCTCCGGTGCCGCCCCGTACGCGTGTCA
AGCGCCCGCCCCGCCCCGCC

Downstream 100 bases:

>100_bases
CCTCCGAGGCTGAAGTGGCTCACGGGGCTAGCGTGAGGGCCAGCCGCACAACCGCCAGACCGAGTCGAGGGGAAGCCGCG
TGGTCCGACGGGTCCGTCTC

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MPVPEGAREVFTDGACSGNPGPGGWAWALDTAVYASGREAPSTNQRMEIRAALEAVRSLDGPLLVVSDSTYVVHCFRDLW
WQGWLDRDWVSSARKPVANRDLWEPLVGLVQDRGDVAFAWVKGHSGHVMNDFVDRLAVAATRA

Sequences:

>Translated_143_residues
MPVPEGAREVFTDGACSGNPGPGGWAWALDTAVYASGREAPSTNQRMEIRAALEAVRSLDGPLLVVSDSTYVVHCFRDLW
WQGWLDRDWVSSARKPVANRDLWEPLVGLVQDRGDVAFAWVKGHSGHVMNDFVDRLAVAATRA
>Mature_142_residues
PVPEGAREVFTDGACSGNPGPGGWAWALDTAVYASGREAPSTNQRMEIRAALEAVRSLDGPLLVVSDSTYVVHCFRDLWW
QGWLDRDWVSSARKPVANRDLWEPLVGLVQDRGDVAFAWVKGHSGHVMNDFVDRLAVAATRA

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Homo sapiens, GI21359816, Length=141, Percent_Identity=34.7517730496454, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1786408, Length=138, Percent_Identity=39.1304347826087, Blast_Score=90, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 15692; Mature: 15561

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPEGAREVFTDGACSGNPGPGGWAWALDTAVYASGREAPSTNQRMEIRAALEAVRSLD
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
GPLLVVSDSTYVVHCFRDLWWQGWLDRDWVSSARKPVANRDLWEPLVGLVQDRGDVAFAW
CCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEE
VKGHSGHVMNDFVDRLAVAATRA
EECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVPEGAREVFTDGACSGNPGPGGWAWALDTAVYASGREAPSTNQRMEIRAALEAVRSLD
CCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
GPLLVVSDSTYVVHCFRDLWWQGWLDRDWVSSARKPVANRDLWEPLVGLVQDRGDVAFAW
CCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEE
VKGHSGHVMNDFVDRLAVAATRA
EECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA