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The map label for this gene is hppA [H]

Identifier: 119714637

GI number: 119714637

Start: 396899

End: 399277

Strand: Direct

Name: hppA [H]

Synonym: Noca_0372

Alternate gene names: 119714637

Gene position: 396899-399277 (Clockwise)

Preceding gene: 119714636

Following gene: 119714639

Centisome position: 7.96

GC content: 70.45

Gene sequence:

>2379_bases
ATGACGGGGATCGTTCCCGCTGTCGTGGAAGTCTCCGGGGGCAATCTCGTCCTGGTCATCGTCGTCGCACTGATCGCGCT
TGGCGCGCTCGCGATGGCAGCGATGTTCCGCCAGGAAGTGCTTGCCGCCGGTGAGGGCACCGACAACATGAAGAACATCG
CGCAGGCGGTGCAAGAGGGCGCGAACGCCTACTTGCAGCGGCAGTTCCGCACGTTGGCGATCTTCGCCGTCGTCGCGTTC
TTCCTGCTGCTCGCGCTGCCCGCCGACGACGCCATGGTCCGGATCTTCCGGTCCGTGTTCTTCCTGGTCGGAGCGGGCTT
CTCGGCCACCGTCGGCTACCTCGGCATGTCGCTCGCGGTGAAGGCGAACCTCCGGGTGGCTGCGGCCGCGCAGACCCAGG
GCCGCGACCCGGCCATGAACATCGGCTTCCGGACCGGCGCCACCGTCGGCATGCTGACCGTCGGCCTCGGCCTGCTCGGC
GCCAGCGTCGTGGTGATCCTGTTCCAGGAGGACGCCCCGCACGTGCTGGAGGGCTTCGGCTTCGGTGCGGCGCTGCTCGC
GATGTTCATGCGTGTCGGCGGCGGCATCTTCACCAAGGCCGCCGACGTCGGCGCCGACCTGGTCGGCAAGGTCGAGAACA
ACATCCCCGAGGACGACCCGCGCAATGCCGCGACGATCGCGGACAACGTCGGCGACAACGTCGGCGACTGCGCGGGCATG
GCTGCCGACCTGTTCGAGTCCTACGCCGTGACCCTGGTCGCGGCGCTGATCCTGGGCTCCCAGGCCTTCGGCGACAAGGG
CCTGGTGTTCCCGCTGCTGATCCCCGCGATCGGTGCCCTGACCGCCGTCGTCGGGGTGTACCTCTGCAAGCCGCGGGCCG
GCGAGAACGGCCTGACCACGATCAACCGGGCGTTCTACATCTCCGCCGCGATCGGCGCGGTCGCGAGCATCATCCTGGCC
CTGGTCTACCTGCCGGGCGACTTCGCCGACCTGACGAACTCCACGGTCGACGCCGACGCCAGCCCGCGTGTCGTCGCCGC
CCTGGCCGTGCTCATCGGCATCGTGCTCGCCGCCGCGATCCTCGGCCTCACCGGCTACTTCACCGGCACCGACCACCGGC
CGGTCAAGGACGTCGGCAAGACCTCGCTCACGGGCGCGGCGACCGTGATCCTGTCCGGCCTGTCGGTCGGCTTCGAGTCG
GCCGTCTACACGACCCTGGTCATCGGCGCGGCGGTCTTCGGCGCGTTCCTGGTCGGTGCCGGCTCGATCCCGGTCGCGCT
GTTCGCGGTCGCGCTGGCCGGCTGCGGCCTGCTGACCACCGTCGGCGTGATCGTCGCGATGGACACCTTCGGCCCGGTCT
CCGACAACGCCCAGGGCATCGCGGAGATGTCCGGCGACGTCGACGAGCACGGCGCGCAGATCCTGACCGAGCTCGACGCG
GTCGGCAACACCACGAAGGCGATCACCAAGGGCATCGCGATCGCGACGGCGGTGCTCGCCGCGAGCGCGCTGTTCGGCTC
CTACACGAACGCCCTCCAGGACGCCATCGACGAGGTCACCCTCACCGAGGAGCCCGGCGCGCTCACCAGCCTGGCGTTCT
CGTTCAACGCGTCCTACCCGAACATCCTGGTCGGCATGCTGCTCGGTGCGGCCGTGGTGTTCCTGTTCTCCGGGCTCGCG
ATCAACGCGGTCGGCCGCGCTGCCGGCGCGGTGGTCTACGAGGTGCGCCGCCAGTTCCGGGAGATCCCCGGGATCATGGA
GGGCACCGGCCGCCCGGAGTACGGCCGTGTGGTCGACATCGTGACCCGCGACTCGCTGCGTGAGCTGGCCACCCCGGGCC
TGCTCGCGATCCTGGCACCGATCGCCGTCGGCTTCGGCCTCGGCGTCGGTCCGCTGGCCGGCTTCCTGGCCGGTGCGATC
GCCACCGGCACGCTGATGGCGGTGTTCCTGGCCAACTCCGGTGGCGCCTGGGACAACGCGAAGAAGCTGGTCGAGGACGG
CAACCACGGCGGCAAGGGCTCGGACGCGCACGCCGCGACGGTCATCGGCGACACCGTCGGCGACCCGTTCAAGGACACCG
CCGGCCCGGCGATCAACCCGCTGCTCAAGGTGATGAACCTGGTCTCGCTGCTGATCGTCGCCGCCATCGTGAAGCTGTCG
ATCGGCGAGGACGCGAACACCCCGCTGCGGATCGTGATCGCCCTGGCGGCGTTCGCGGGCATCGTCGCCGCGGTGTACGT
CTCCAAGCGGCGCCCGGTCCACATCGAGGGCGACGACGACGGTACGACGGCTCCCCCGCCGCCTCCGCCGCCGGTCGAGG
CCGTGCCGCCGACGGAGCCCGCTCCGACCCAGCAGTTCGAGGCGCCCCAGCAGCACTAG

Upstream 100 bases:

>100_bases
TCCAGCTGTGTACCGGGTCACATGTGCGTACCCGCCCGCAGCCCGTGCGTAGACTCCGCGTCGTCCGTGAGACCTGAATC
ACTCTCCCAGGAGGAAACAC

Downstream 100 bases:

>100_bases
CCTCGCAGCCCTGAAATGACGTCGACCCGCCCGAAGCCTTCGGGCGGGTCGACGTCGTCTCGGGCTACTTCTTGACGGTC
AGCTTCACCACCTTGGACCT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MTGIVPAVVEVSGGNLVLVIVVALIALGALAMAAMFRQEVLAAGEGTDNMKNIAQAVQEGANAYLQRQFRTLAIFAVVAF
FLLLALPADDAMVRIFRSVFFLVGAGFSATVGYLGMSLAVKANLRVAAAAQTQGRDPAMNIGFRTGATVGMLTVGLGLLG
ASVVVILFQEDAPHVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVENNIPEDDPRNAATIADNVGDNVGDCAGM
AADLFESYAVTLVAALILGSQAFGDKGLVFPLLIPAIGALTAVVGVYLCKPRAGENGLTTINRAFYISAAIGAVASIILA
LVYLPGDFADLTNSTVDADASPRVVAALAVLIGIVLAAAILGLTGYFTGTDHRPVKDVGKTSLTGAATVILSGLSVGFES
AVYTTLVIGAAVFGAFLVGAGSIPVALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVDEHGAQILTELDA
VGNTTKAITKGIAIATAVLAASALFGSYTNALQDAIDEVTLTEEPGALTSLAFSFNASYPNILVGMLLGAAVVFLFSGLA
INAVGRAAGAVVYEVRRQFREIPGIMEGTGRPEYGRVVDIVTRDSLRELATPGLLAILAPIAVGFGLGVGPLAGFLAGAI
ATGTLMAVFLANSGGAWDNAKKLVEDGNHGGKGSDAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVSLLIVAAIVKLS
IGEDANTPLRIVIALAAFAGIVAAVYVSKRRPVHIEGDDDGTTAPPPPPPPVEAVPPTEPAPTQQFEAPQQH

Sequences:

>Translated_792_residues
MTGIVPAVVEVSGGNLVLVIVVALIALGALAMAAMFRQEVLAAGEGTDNMKNIAQAVQEGANAYLQRQFRTLAIFAVVAF
FLLLALPADDAMVRIFRSVFFLVGAGFSATVGYLGMSLAVKANLRVAAAAQTQGRDPAMNIGFRTGATVGMLTVGLGLLG
ASVVVILFQEDAPHVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVENNIPEDDPRNAATIADNVGDNVGDCAGM
AADLFESYAVTLVAALILGSQAFGDKGLVFPLLIPAIGALTAVVGVYLCKPRAGENGLTTINRAFYISAAIGAVASIILA
LVYLPGDFADLTNSTVDADASPRVVAALAVLIGIVLAAAILGLTGYFTGTDHRPVKDVGKTSLTGAATVILSGLSVGFES
AVYTTLVIGAAVFGAFLVGAGSIPVALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVDEHGAQILTELDA
VGNTTKAITKGIAIATAVLAASALFGSYTNALQDAIDEVTLTEEPGALTSLAFSFNASYPNILVGMLLGAAVVFLFSGLA
INAVGRAAGAVVYEVRRQFREIPGIMEGTGRPEYGRVVDIVTRDSLRELATPGLLAILAPIAVGFGLGVGPLAGFLAGAI
ATGTLMAVFLANSGGAWDNAKKLVEDGNHGGKGSDAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVSLLIVAAIVKLS
IGEDANTPLRIVIALAAFAGIVAAVYVSKRRPVHIEGDDDGTTAPPPPPPPVEAVPPTEPAPTQQFEAPQQH
>Mature_791_residues
TGIVPAVVEVSGGNLVLVIVVALIALGALAMAAMFRQEVLAAGEGTDNMKNIAQAVQEGANAYLQRQFRTLAIFAVVAFF
LLLALPADDAMVRIFRSVFFLVGAGFSATVGYLGMSLAVKANLRVAAAAQTQGRDPAMNIGFRTGATVGMLTVGLGLLGA
SVVVILFQEDAPHVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVENNIPEDDPRNAATIADNVGDNVGDCAGMA
ADLFESYAVTLVAALILGSQAFGDKGLVFPLLIPAIGALTAVVGVYLCKPRAGENGLTTINRAFYISAAIGAVASIILAL
VYLPGDFADLTNSTVDADASPRVVAALAVLIGIVLAAAILGLTGYFTGTDHRPVKDVGKTSLTGAATVILSGLSVGFESA
VYTTLVIGAAVFGAFLVGAGSIPVALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVDEHGAQILTELDAV
GNTTKAITKGIAIATAVLAASALFGSYTNALQDAIDEVTLTEEPGALTSLAFSFNASYPNILVGMLLGAAVVFLFSGLAI
NAVGRAAGAVVYEVRRQFREIPGIMEGTGRPEYGRVVDIVTRDSLRELATPGLLAILAPIAVGFGLGVGPLAGFLAGAIA
TGTLMAVFLANSGGAWDNAKKLVEDGNHGGKGSDAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVSLLIVAAIVKLSI
GEDANTPLRIVIALAAFAGIVAAVYVSKRRPVHIEGDDDGTTAPPPPPPPVEAVPPTEPAPTQQFEAPQQH

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 80398; Mature: 80267

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIVPAVVEVSGGNLVLVIVVALIALGALAMAAMFRQEVLAAGEGTDNMKNIAQAVQEG
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ANAYLQRQFRTLAIFAVVAFFLLLALPADDAMVRIFRSVFFLVGAGFSATVGYLGMSLAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEE
KANLRVAAAAQTQGRDPAMNIGFRTGATVGMLTVGLGLLGASVVVILFQEDAPHVLEGFG
EECCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHCC
FGAALLAMFMRVGGGIFTKAADVGADLVGKVENNIPEDDPRNAATIADNVGDNVGDCAGM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHH
AADLFESYAVTLVAALILGSQAFGDKGLVFPLLIPAIGALTAVVGVYLCKPRAGENGLTT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
INRAFYISAAIGAVASIILALVYLPGDFADLTNSTVDADASPRVVAALAVLIGIVLAAAI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LGLTGYFTGTDHRPVKDVGKTSLTGAATVILSGLSVGFESAVYTTLVIGAAVFGAFLVGA
HHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSIPVALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVDEHGAQILTELDA
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
VGNTTKAITKGIAIATAVLAASALFGSYTNALQDAIDEVTLTEEPGALTSLAFSFNASYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHHEEEECCCCH
NILVGMLLGAAVVFLFSGLAINAVGRAAGAVVYEVRRQFREIPGIMEGTGRPEYGRVVDI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEH
VTRDSLRELATPGLLAILAPIAVGFGLGVGPLAGFLAGAIATGTLMAVFLANSGGAWDNA
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KKLVEDGNHGGKGSDAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVSLLIVAAIVKLS
HHHHHCCCCCCCCCCCCHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGEDANTPLRIVIALAAFAGIVAAVYVSKRRPVHIEGDDDGTTAPPPPPPPVEAVPPTEP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
APTQQFEAPQQH
CCCCCCCCCCCC
>Mature Secondary Structure 
TGIVPAVVEVSGGNLVLVIVVALIALGALAMAAMFRQEVLAAGEGTDNMKNIAQAVQEG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ANAYLQRQFRTLAIFAVVAFFLLLALPADDAMVRIFRSVFFLVGAGFSATVGYLGMSLAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEE
KANLRVAAAAQTQGRDPAMNIGFRTGATVGMLTVGLGLLGASVVVILFQEDAPHVLEGFG
EECCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHCC
FGAALLAMFMRVGGGIFTKAADVGADLVGKVENNIPEDDPRNAATIADNVGDNVGDCAGM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHH
AADLFESYAVTLVAALILGSQAFGDKGLVFPLLIPAIGALTAVVGVYLCKPRAGENGLTT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
INRAFYISAAIGAVASIILALVYLPGDFADLTNSTVDADASPRVVAALAVLIGIVLAAAI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LGLTGYFTGTDHRPVKDVGKTSLTGAATVILSGLSVGFESAVYTTLVIGAAVFGAFLVGA
HHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSIPVALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVDEHGAQILTELDA
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
VGNTTKAITKGIAIATAVLAASALFGSYTNALQDAIDEVTLTEEPGALTSLAFSFNASYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHHEEEECCCCH
NILVGMLLGAAVVFLFSGLAINAVGRAAGAVVYEVRRQFREIPGIMEGTGRPEYGRVVDI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEH
VTRDSLRELATPGLLAILAPIAVGFGLGVGPLAGFLAGAIATGTLMAVFLANSGGAWDNA
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KKLVEDGNHGGKGSDAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVSLLIVAAIVKLS
HHHHHCCCCCCCCCCCCHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGEDANTPLRIVIALAAFAGIVAAVYVSKRRPVHIEGDDDGTTAPPPPPPPVEAVPPTEP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
APTQQFEAPQQH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]