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The map label for this gene is lytT [H]

Identifier: 119714623

GI number: 119714623

Start: 382702

End: 383451

Strand: Reverse

Name: lytT [H]

Synonym: Noca_0357

Alternate gene names: 119714623

Gene position: 383451-382702 (Counterclockwise)

Preceding gene: 119714624

Following gene: 119714622

Centisome position: 7.69

GC content: 74.93

Gene sequence:

>750_bases
GTGAGCGCGCCGGCGGCTCCCGTCCCGCGGCTCCGGGCGCTCGTCGTCGACGACGAGCGGCCCGCGCTCGACGAGCTGCG
CTACCTGCTCGAGCGCGACGACCGCGTCCGCGAGGTGCTGACCACCGACTCGGCGACCGAGGGGCTCCGGATCCTGCGCG
ACCTCGACGTGGACGTGGTGTTCCTCGACATCCAGATGCCGGGGCTGACCGGCCTCGAGCTCGCGCAGGTGCTCAGCCGG
TTCCGCACCCCACCCGGCATCGTGTTCGTCACCGCCCACGAGGCCCACGCCGTGGAGGCCTTCGATGTGCACGCCGTCGA
CTACGTGCTCAAGCCGGTGCGCGCCGACCGGCTGGCCGAGGCGGTCCGCCGGGTGGTGGCCGGCACCGACCGGGCGGCGA
ACGGCGACGACATGCGGGTCGCGGTGGAGCGCGGCGGCGTCACCCGCTTCCTGAACCGCTCCGACATCACCCACGTGGAG
GCGCACGGCGACTACGCGCGGCTGCACACCGGCGACGGCTCCCACCTGGTGCGCACCCCGCTCGCCGCCCTGGAGGAGGA
GTGGGCGGGTGCCGGCTTCGTGCGGATCCACCGGTCCCTGCTGGTCTCGCTCGCCCACGTGCGCGAGGTGCGGATGGACG
CGGGCCGCTGCGCGGTCGTCGTCGGCGAGCCGCCGGTCGAGCTCGGCGTCAGCCGACGGCACACCCGGGAGCTGCGCGAG
CTGCTGCTCCAGTACCGGACCGGGCCGTGA

Upstream 100 bases:

>100_bases
ACGCCTTCGGCGACGACTTCGGCCTCGCGGTGGAGACCGCACCGGGCGCGGGCACCAAGGTCGTGGTCAGGGTGCCGAAG
TTCGCTCCCGGGGTGCACGC

Downstream 100 bases:

>100_bases
GCGAGCCGGGGGCAGCGCCCGAACGGGTCCGGGTGACCGGCCCGCCGCGCCGCCGTACCCCCGCCGCCCGCACGGCCGAC
ATCGACGACGAGACCCTGCT

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSAPAAPVPRLRALVVDDERPALDELRYLLERDDRVREVLTTDSATEGLRILRDLDVDVVFLDIQMPGLTGLELAQVLSR
FRTPPGIVFVTAHEAHAVEAFDVHAVDYVLKPVRADRLAEAVRRVVAGTDRAANGDDMRVAVERGGVTRFLNRSDITHVE
AHGDYARLHTGDGSHLVRTPLAALEEEWAGAGFVRIHRSLLVSLAHVREVRMDAGRCAVVVGEPPVELGVSRRHTRELRE
LLLQYRTGP

Sequences:

>Translated_249_residues
MSAPAAPVPRLRALVVDDERPALDELRYLLERDDRVREVLTTDSATEGLRILRDLDVDVVFLDIQMPGLTGLELAQVLSR
FRTPPGIVFVTAHEAHAVEAFDVHAVDYVLKPVRADRLAEAVRRVVAGTDRAANGDDMRVAVERGGVTRFLNRSDITHVE
AHGDYARLHTGDGSHLVRTPLAALEEEWAGAGFVRIHRSLLVSLAHVREVRMDAGRCAVVVGEPPVELGVSRRHTRELRE
LLLQYRTGP
>Mature_248_residues
SAPAAPVPRLRALVVDDERPALDELRYLLERDDRVREVLTTDSATEGLRILRDLDVDVVFLDIQMPGLTGLELAQVLSRF
RTPPGIVFVTAHEAHAVEAFDVHAVDYVLKPVRADRLAEAVRRVVAGTDRAANGDDMRVAVERGGVTRFLNRSDITHVEA
HGDYARLHTGDGSHLVRTPLAALEEEWAGAGFVRIHRSLLVSLAHVREVRMDAGRCAVVVGEPPVELGVSRRHTRELREL
LLQYRTGP

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=242, Percent_Identity=30.1652892561983, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082052, Length=243, Percent_Identity=31.2757201646091, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27602; Mature: 27471

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPAAPVPRLRALVVDDERPALDELRYLLERDDRVREVLTTDSATEGLRILRDLDVDVV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCEEE
FLDIQMPGLTGLELAQVLSRFRTPPGIVFVTAHEAHAVEAFDVHAVDYVLKPVRADRLAE
EEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHH
AVRRVVAGTDRAANGDDMRVAVERGGVTRFLNRSDITHVEAHGDYARLHTGDGSHLVRTP
HHHHHHHCCCCCCCCCCEEEEEECCCHHHHCCCCCCEEEECCCCEEEEECCCCCHHHHHH
LAALEEEWAGAGFVRIHRSLLVSLAHVREVRMDAGRCAVVVGEPPVELGVSRRHTRELRE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCHHHHHHHHH
LLLQYRTGP
HHHHHCCCC
>Mature Secondary Structure 
SAPAAPVPRLRALVVDDERPALDELRYLLERDDRVREVLTTDSATEGLRILRDLDVDVV
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCEEE
FLDIQMPGLTGLELAQVLSRFRTPPGIVFVTAHEAHAVEAFDVHAVDYVLKPVRADRLAE
EEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHH
AVRRVVAGTDRAANGDDMRVAVERGGVTRFLNRSDITHVEAHGDYARLHTGDGSHLVRTP
HHHHHHHCCCCCCCCCCEEEEEECCCHHHHCCCCCCEEEECCCCEEEEECCCCCHHHHHH
LAALEEEWAGAGFVRIHRSLLVSLAHVREVRMDAGRCAVVVGEPPVELGVSRRHTRELRE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCHHHHHHHHH
LLLQYRTGP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]