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The map label for this gene is ywcA [H]

Identifier: 119714613

GI number: 119714613

Start: 369471

End: 371075

Strand: Reverse

Name: ywcA [H]

Synonym: Noca_0347

Alternate gene names: 119714613

Gene position: 371075-369471 (Counterclockwise)

Preceding gene: 119714614

Following gene: 119714612

Centisome position: 7.44

GC content: 68.72

Gene sequence:

>1605_bases
ATGAGCTCCGACACCCTGACCGCGATCCTGTTCATCGGGGTCGTCCTGATCACCATCGCCATCACGTTCTGGGCGAGCCG
ACAGAACAAGGGCACCGCGGACTTCTACGCCGCCGGCCGTTCCTTCAGTGGCTTCCAGAACGGCATGGCGATCTCCGGCG
ACTACATGTCGGCGGCGTCGTTCCTCGGCATCTCGGGCGCCATCGCGCTGTACGGGTACGACGGGTTCCTCTACTCGATC
GGCTTCCTGGTGGCCTGGCTGGTCGCCCTGCTGCTGGTCGCCGAGCTGCTGCGCAACTCCGGCCGCTACACGATGGCCGA
CCAGCTGGCCTACCGGATGCGGCAGCGCCCGGTCCGGACCGCGGCGTCCACCTCGACCGTGGTGGTCTCGATCTTCTACC
TGCTCGCCCAGATGGTCGGCGCGGGGGCCCTGGTCGCACTGCTCCTCGGCGCGGACTCCGAGGCAGCCAAGAACGCCACG
ATCATCGGGGTCGGCGTGCTGATGATCTTCTACGTCACCGTCGGCGGCATGAAGGGCACCACCTGGGTGCAGATCGTCAA
GGCGGTGCTGCTGATGGGCGGCACCATCTTGATCACGATCCTGGTGCTGGCGAAGTTCAACTTCAACATCTCCGACCTGC
TCGGCGCGGCTGCGGCCAACACCGGCAAGGGCGACGCCTTCCTCCAGCCGGGACTGAAGTACGGGATCGACACGACCGCG
AAGATCGACTTCCTCAGCCTCGGCCTCGCGCTGGTGCTCGGTACGGCGGGCCTGCCGCACATCCTGATCCGCTTCTACAC
CGTGCCGAGCGCCAAGGCGGCGCGCACCTCGGTGTTGTGGGCGATCGGGCTGATCGGCGCGTTCTACCTGATGACGCTCG
CGCTCGGCTTCGGTGCCGCGGCGCTGCTCGACACCGGTGCCGGGAGCAAGGTGGCGGCGTCCGGCGGCAACCTCGCCTCA
CCACTGCTCGCCGAAGCCGTCGGCGGTGGCGACGGGACCACGGGCGGCGCGGTCCTGCTGGCGCTGATCTCCGCCGTCGC
GTTCGCGACGATCCTGGCGGTCGTCGCGGGCCTGACGCTCACCTCGGCGTCGTCCGTGGCCCACGACCTCTACGCGACGG
TCTTCAAGAAGGGTGCGGCGACCGAGCGCGACGAGGTACGGGTGGCCCGGCTCTCGGCGTTCGTGATCGGTGGCATCGCG
ATCGCGCTGGCCATCCCGGCGCAGAAGCTCAACATCGCGTTCCTCGTGGCGCTGGCCTTCGCGGTCGCCGCCTCGGCGAA
CCTGCCCTCGCTGATCTACAACCTGTTCTGGCGCCGCTTCAACACCCGCGGTGCCACCTGGGCGATCTACGGCGGCCTGA
TCGCCAGCGTGGGCCTGGTGTTCTTCTCGCCGGTCGTGTCCGGCTCGGAGACGGCGCTGTTCACCGGTCAGGACTGGTCG
TACTTCCCGCTCAGCAACCCCGGCATCATCTCGATCCCGCTCGGCTTCTTCTTCGGGTGGCTCGGCACCGTCACCTCCCA
GGAGCCGGAGAGCGCCGCGCGGTTCACCGAGCTCGAGGTCCGGGCCTTCACCGGCGCGGGCGCCGAGCAGGCCGTCCGGC
ACTGA

Upstream 100 bases:

>100_bases
CGATCGCCTGGCTCTACGCGCGCTACATGAACCGCAACGTCGACCCGATCGCGCGGGCCCTCGAGAAGAAGTACAACGAC
CGGCCCGGCGGAGGTGCCCG

Downstream 100 bases:

>100_bases
CCCACCTGCATCACCCTTCGCGGGCGGGTGCCCGGCGGCCGCGGTCGCCGGGCACCCGGCCACGTCCTAGTGTGGCTCGT
ACCACAGTCACACAGCACCG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSSDTLTAILFIGVVLITIAITFWASRQNKGTADFYAAGRSFSGFQNGMAISGDYMSAASFLGISGAIALYGYDGFLYSI
GFLVAWLVALLLVAELLRNSGRYTMADQLAYRMRQRPVRTAASTSTVVVSIFYLLAQMVGAGALVALLLGADSEAAKNAT
IIGVGVLMIFYVTVGGMKGTTWVQIVKAVLLMGGTILITILVLAKFNFNISDLLGAAAANTGKGDAFLQPGLKYGIDTTA
KIDFLSLGLALVLGTAGLPHILIRFYTVPSAKAARTSVLWAIGLIGAFYLMTLALGFGAAALLDTGAGSKVAASGGNLAS
PLLAEAVGGGDGTTGGAVLLALISAVAFATILAVVAGLTLTSASSVAHDLYATVFKKGAATERDEVRVARLSAFVIGGIA
IALAIPAQKLNIAFLVALAFAVAASANLPSLIYNLFWRRFNTRGATWAIYGGLIASVGLVFFSPVVSGSETALFTGQDWS
YFPLSNPGIISIPLGFFFGWLGTVTSQEPESAARFTELEVRAFTGAGAEQAVRH

Sequences:

>Translated_534_residues
MSSDTLTAILFIGVVLITIAITFWASRQNKGTADFYAAGRSFSGFQNGMAISGDYMSAASFLGISGAIALYGYDGFLYSI
GFLVAWLVALLLVAELLRNSGRYTMADQLAYRMRQRPVRTAASTSTVVVSIFYLLAQMVGAGALVALLLGADSEAAKNAT
IIGVGVLMIFYVTVGGMKGTTWVQIVKAVLLMGGTILITILVLAKFNFNISDLLGAAAANTGKGDAFLQPGLKYGIDTTA
KIDFLSLGLALVLGTAGLPHILIRFYTVPSAKAARTSVLWAIGLIGAFYLMTLALGFGAAALLDTGAGSKVAASGGNLAS
PLLAEAVGGGDGTTGGAVLLALISAVAFATILAVVAGLTLTSASSVAHDLYATVFKKGAATERDEVRVARLSAFVIGGIA
IALAIPAQKLNIAFLVALAFAVAASANLPSLIYNLFWRRFNTRGATWAIYGGLIASVGLVFFSPVVSGSETALFTGQDWS
YFPLSNPGIISIPLGFFFGWLGTVTSQEPESAARFTELEVRAFTGAGAEQAVRH
>Mature_533_residues
SSDTLTAILFIGVVLITIAITFWASRQNKGTADFYAAGRSFSGFQNGMAISGDYMSAASFLGISGAIALYGYDGFLYSIG
FLVAWLVALLLVAELLRNSGRYTMADQLAYRMRQRPVRTAASTSTVVVSIFYLLAQMVGAGALVALLLGADSEAAKNATI
IGVGVLMIFYVTVGGMKGTTWVQIVKAVLLMGGTILITILVLAKFNFNISDLLGAAAANTGKGDAFLQPGLKYGIDTTAK
IDFLSLGLALVLGTAGLPHILIRFYTVPSAKAARTSVLWAIGLIGAFYLMTLALGFGAAALLDTGAGSKVAASGGNLASP
LLAEAVGGGDGTTGGAVLLALISAVAFATILAVVAGLTLTSASSVAHDLYATVFKKGAATERDEVRVARLSAFVIGGIAI
ALAIPAQKLNIAFLVALAFAVAASANLPSLIYNLFWRRFNTRGATWAIYGGLIASVGLVFFSPVVSGSETALFTGQDWSY
FPLSNPGIISIPLGFFFGWLGTVTSQEPESAARFTELEVRAFTGAGAEQAVRH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=533, Percent_Identity=46.1538461538462, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1787251, Length=459, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55383; Mature: 55252

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDTLTAILFIGVVLITIAITFWASRQNKGTADFYAAGRSFSGFQNGMAISGDYMSAAS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCCHHHHHH
FLGISGAIALYGYDGFLYSIGFLVAWLVALLLVAELLRNSGRYTMADQLAYRMRQRPVRT
HHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHH
AASTSTVVVSIFYLLAQMVGAGALVALLLGADSEAAKNATIIGVGVLMIFYVTVGGMKGT
HHCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHCCCEEHHHHHHHHHHHHHCCCCCH
TWVQIVKAVLLMGGTILITILVLAKFNFNISDLLGAAAANTGKGDAFLQPGLKYGIDTTA
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHCCCCHHCCCCCCC
KIDFLSLGLALVLGTAGLPHILIRFYTVPSAKAARTSVLWAIGLIGAFYLMTLALGFGAA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ALLDTGAGSKVAASGGNLASPLLAEAVGGGDGTTGGAVLLALISAVAFATILAVVAGLTL
HHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSASSVAHDLYATVFKKGAATERDEVRVARLSAFVIGGIAIALAIPAQKLNIAFLVALAF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AVAASANLPSLIYNLFWRRFNTRGATWAIYGGLIASVGLVFFSPVVSGSETALFTGQDWS
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YFPLSNPGIISIPLGFFFGWLGTVTSQEPESAARFTELEVRAFTGAGAEQAVRH
CCCCCCCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHEEEEEECCCCHHHHHCC
>Mature Secondary Structure 
SSDTLTAILFIGVVLITIAITFWASRQNKGTADFYAAGRSFSGFQNGMAISGDYMSAAS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCCHHHHHH
FLGISGAIALYGYDGFLYSIGFLVAWLVALLLVAELLRNSGRYTMADQLAYRMRQRPVRT
HHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHH
AASTSTVVVSIFYLLAQMVGAGALVALLLGADSEAAKNATIIGVGVLMIFYVTVGGMKGT
HHCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHCCCEEHHHHHHHHHHHHHCCCCCH
TWVQIVKAVLLMGGTILITILVLAKFNFNISDLLGAAAANTGKGDAFLQPGLKYGIDTTA
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHCCCCHHCCCCCCC
KIDFLSLGLALVLGTAGLPHILIRFYTVPSAKAARTSVLWAIGLIGAFYLMTLALGFGAA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ALLDTGAGSKVAASGGNLASPLLAEAVGGGDGTTGGAVLLALISAVAFATILAVVAGLTL
HHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSASSVAHDLYATVFKKGAATERDEVRVARLSAFVIGGIAIALAIPAQKLNIAFLVALAF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AVAASANLPSLIYNLFWRRFNTRGATWAIYGGLIASVGLVFFSPVVSGSETALFTGQDWS
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YFPLSNPGIISIPLGFFFGWLGTVTSQEPESAARFTELEVRAFTGAGAEQAVRH
CCCCCCCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHEEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]