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The map label for this gene is scoA [H]

Identifier: 119714596

GI number: 119714596

Start: 354203

End: 354976

Strand: Direct

Name: scoA [H]

Synonym: Noca_0330

Alternate gene names: 119714596

Gene position: 354203-354976 (Clockwise)

Preceding gene: 119714593

Following gene: 119714597

Centisome position: 7.1

GC content: 71.83

Gene sequence:

>774_bases
GTGGACAAGGTGGTGGCGTCGGCGACAGCCGCGGTGGCGGACATCCCGGACGGGGTGACGCTGTCCGTCGGTGGGTTCGG
GTTGTGCGGGATCCCCTCGGTGCTGATCCAGGCGGTGCTCGACCGCGGCACCCAGGACCTGGAGGTGGTCTCGAACAACG
CCGGCGTGGACGGGTGGGGCCTGGGCCTGCTCCTCGGCGCCGGGCGGCTGCGGCGGGTGGTGGCGTCGTACGTCGGGGAG
AACAAGGAGTTCGCCCGCCAGTACCTCTCCGGCGAGCTGGAGGTGGAGCTGACCCCGCAGGGCACGCTCGCGGAGCGGAT
GCGTGCCGGCGGGTCGGGGATCCCGGCGTTCTTCACCGCGACCGGCGTGGGCACCCAGGTGGCCGAGGGCGGGCTGCCGT
GGCGCTACGACGCCGAGGGGGCGGTGGTGAAGTCCTCGCCGGCCAAGCAGACCCAGGTCTTCGAGACCGCGGAGGGGCCC
AAGGAGTTCGTGCTCGAGCACGCGATCGTCGCGGACTTCGGCCTGGTGCGGGCCTGGAAGGGCGACCGCCACGGCAACCT
GGTGTTCCGCGACTCGGCTCGCAACTTCAACCCGTTGGCGGCGATGTGCGGGCGGGTCACGATCGCGGAGGTCGAGCACC
TGGTCGAGCCGGGTGAGCTCGACCCCAACCAGGTGCACACCCCGGGGGTGTTCGTGCAGCGGGTGGTGGAGCTGACCCCG
GAGCAGGCCGCGGACAAGCGGATCGAGAAGAAGACGGTGAGGGCACGCGGATGA

Upstream 100 bases:

>100_bases
TCGTCGGCGGAGCCATGGGGCTGAGCCTAGATGAGACGCAGGGGGCCCTAGGATCGACGAGACCCGGGTCACAGCTGGTC
CCGGGGGAGGAGGAGTTGGC

Downstream 100 bases:

>100_bases
GCTGGAGTCGTGAGGAGATGGCGGCGCGGGCGGCCTCGGAGCTCTCCGACGGGTCGTACGTGAACCTCGGGATCGGGCTG
CCGACGATGGTGCCCAACTA

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDKVVASATAAVADIPDGVTLSVGGFGLCGIPSVLIQAVLDRGTQDLEVVSNNAGVDGWGLGLLLGAGRLRRVVASYVGE
NKEFARQYLSGELEVELTPQGTLAERMRAGGSGIPAFFTATGVGTQVAEGGLPWRYDAEGAVVKSSPAKQTQVFETAEGP
KEFVLEHAIVADFGLVRAWKGDRHGNLVFRDSARNFNPLAAMCGRVTIAEVEHLVEPGELDPNQVHTPGVFVQRVVELTP
EQAADKRIEKKTVRARG

Sequences:

>Translated_257_residues
MDKVVASATAAVADIPDGVTLSVGGFGLCGIPSVLIQAVLDRGTQDLEVVSNNAGVDGWGLGLLLGAGRLRRVVASYVGE
NKEFARQYLSGELEVELTPQGTLAERMRAGGSGIPAFFTATGVGTQVAEGGLPWRYDAEGAVVKSSPAKQTQVFETAEGP
KEFVLEHAIVADFGLVRAWKGDRHGNLVFRDSARNFNPLAAMCGRVTIAEVEHLVEPGELDPNQVHTPGVFVQRVVELTP
EQAADKRIEKKTVRARG
>Mature_257_residues
MDKVVASATAAVADIPDGVTLSVGGFGLCGIPSVLIQAVLDRGTQDLEVVSNNAGVDGWGLGLLLGAGRLRRVVASYVGE
NKEFARQYLSGELEVELTPQGTLAERMRAGGSGIPAFFTATGVGTQVAEGGLPWRYDAEGAVVKSSPAKQTQVFETAEGP
KEFVLEHAIVADFGLVRAWKGDRHGNLVFRDSARNFNPLAAMCGRVTIAEVEHLVEPGELDPNQVHTPGVFVQRVVELTP
EQAADKRIEKKTVRARG

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=255, Percent_Identity=52.5490196078431, Blast_Score=271, Evalue=6e-73,
Organism=Homo sapiens, GI11545841, Length=251, Percent_Identity=52.191235059761, Blast_Score=238, Evalue=3e-63,
Organism=Escherichia coli, GI1788551, Length=220, Percent_Identity=41.3636363636364, Blast_Score=170, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17531517, Length=236, Percent_Identity=54.2372881355932, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=49.2, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=49.2, Blast_Score=240, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 27274; Mature: 27274

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVVASATAAVADIPDGVTLSVGGFGLCGIPSVLIQAVLDRGTQDLEVVSNNAGVDGWG
CCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHH
LGLLLGAGRLRRVVASYVGENKEFARQYLSGELEVELTPQGTLAERMRAGGSGIPAFFTA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCEEEE
TGVGTQVAEGGLPWRYDAEGAVVKSSPAKQTQVFETAEGPKEFVLEHAIVADFGLVRAWK
CCCCHHHHCCCCCEEECCCCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
GDRHGNLVFRDSARNFNPLAAMCGRVTIAEVEHLVEPGELDPNQVHTPGVFVQRVVELTP
CCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
EQAADKRIEKKTVRARG
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKVVASATAAVADIPDGVTLSVGGFGLCGIPSVLIQAVLDRGTQDLEVVSNNAGVDGWG
CCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHH
LGLLLGAGRLRRVVASYVGENKEFARQYLSGELEVELTPQGTLAERMRAGGSGIPAFFTA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCEEEE
TGVGTQVAEGGLPWRYDAEGAVVKSSPAKQTQVFETAEGPKEFVLEHAIVADFGLVRAWK
CCCCHHHHCCCCCEEECCCCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
GDRHGNLVFRDSARNFNPLAAMCGRVTIAEVEHLVEPGELDPNQVHTPGVFVQRVVELTP
CCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
EQAADKRIEKKTVRARG
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]