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The map label for this gene is mmgC [H]

Identifier: 119714538

GI number: 119714538

Start: 293627

End: 294772

Strand: Direct

Name: mmgC [H]

Synonym: Noca_0271

Alternate gene names: 119714538

Gene position: 293627-294772 (Clockwise)

Preceding gene: 119714537

Following gene: 119714539

Centisome position: 5.89

GC content: 67.71

Gene sequence:

>1146_bases
ATGAAGCGCAGCATCTACGACGACGACCACGAGGCGTTCCGCGACTCGGTGCGCGAGTTCCTCGAGCGGTCGGTCATCCC
CCAGGTCGAGCAGCACGCCGCCGACAAGGCGATCCCGCGGGACTTCTGGACCGAGGCCGGCAGGCAGGGCTTCCTGGGCC
TGGAGATCCCGGAGGAGTACGGCGGGGCCGAGGCCGGCGACTACCGCTTCAACGCGGTGCTCCTCGAGGAGCTGAACAAG
GTGAACGCCGCGCTCGGCTCGTGCGTCGGCATCCACGCCGACATCACCGCGCCCTACCTCGTCGAGCTCGGCACCGACGA
GCAGAAGCAGCGCTGGCTGCCGGGCGTGGCTGCGGGTGAGGTCCTGCTGGCCATCGGGATGACCGAGCCGTCCGGCGGCT
CCGACCTCGCCGCGCTGAAGACCACGGCCGTCAAGGACGGCGACTCCTGGGTGATCAACGGCTCCAAGACGTTCATCACC
AACGGCTACTCCGCCGACCTCGTGCTCGTCGCGGCGCGCACGTCGCCGGAGAAGAAGGCCCGCGGCATCACCCTGTTCGC
CGTCGAGTCCACGGCACCCGGCTACAGCCGAGGCCGCAAGCTCGACAAGATCGGCCAGGACGAGTCCGACACCGCCGAGC
TGTTCTTCGAGAACGTCCGCGTCACCGACGCCGAGATCGTCGGCGAGCTCGACGGTGGCTTCATCCACATGATGCAGAAG
CTGCCGCAGGAGCGGCTCGGCTGTGCGATCTCCAACGTCGCGCACGCCAAGCAGATCCTCCTCGAGACGCTGCAGTACGC
CAAGGACCGCAAGGCGTTCGGCCAGGGCATCGGCTCCTTCCAGTACAACAAGTTCCTGCTCGCCGAGCTGTTCACCCGGA
TCGAGGTGACCGAGGCGTTCATCGACCAGTGCGTGGTGGCGCACGCGGCGGGCGAGCTCACCCCCATCGATGCAGCCAAG
GCGAAGTGGTGGAGCTCGCAGGTGCAGAACGAGGTGCTCGACCACTGTGTGCAGCTGCACGGCGGCTACGGCTACATGAA
CGAATACCGCGTCGCGCGGGCCTGGCGGGACGCCCGGGTCTCGAAGATCTGGGCCGGCTCCAACGAGATCATGAAGGAGC
TGATCGGCCGCGACCTGGGGCTGTGA

Upstream 100 bases:

>100_bases
GCGGTCGTCGCGCTCTCACTGGTCGCGATCTCGGCGGTGATGACGCGGCGGATCGCCGAGCCGGTTACCGACTAGTAGCA
ACCGTCGTAGGATGCCCGCC

Downstream 100 bases:

>100_bases
GGGCCGTCCGACCGACGAGTGAGCCGAGGCAACCCTTGCTTGCGAGGGCCTCGGGCGCAGCGTTGGATTGACGCCATGAC
CACGAGCGAGATCGAGGTCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKRSIYDDDHEAFRDSVREFLERSVIPQVEQHAADKAIPRDFWTEAGRQGFLGLEIPEEYGGAEAGDYRFNAVLLEELNK
VNAALGSCVGIHADITAPYLVELGTDEQKQRWLPGVAAGEVLLAIGMTEPSGGSDLAALKTTAVKDGDSWVINGSKTFIT
NGYSADLVLVAARTSPEKKARGITLFAVESTAPGYSRGRKLDKIGQDESDTAELFFENVRVTDAEIVGELDGGFIHMMQK
LPQERLGCAISNVAHAKQILLETLQYAKDRKAFGQGIGSFQYNKFLLAELFTRIEVTEAFIDQCVVAHAAGELTPIDAAK
AKWWSSQVQNEVLDHCVQLHGGYGYMNEYRVARAWRDARVSKIWAGSNEIMKELIGRDLGL

Sequences:

>Translated_381_residues
MKRSIYDDDHEAFRDSVREFLERSVIPQVEQHAADKAIPRDFWTEAGRQGFLGLEIPEEYGGAEAGDYRFNAVLLEELNK
VNAALGSCVGIHADITAPYLVELGTDEQKQRWLPGVAAGEVLLAIGMTEPSGGSDLAALKTTAVKDGDSWVINGSKTFIT
NGYSADLVLVAARTSPEKKARGITLFAVESTAPGYSRGRKLDKIGQDESDTAELFFENVRVTDAEIVGELDGGFIHMMQK
LPQERLGCAISNVAHAKQILLETLQYAKDRKAFGQGIGSFQYNKFLLAELFTRIEVTEAFIDQCVVAHAAGELTPIDAAK
AKWWSSQVQNEVLDHCVQLHGGYGYMNEYRVARAWRDARVSKIWAGSNEIMKELIGRDLGL
>Mature_381_residues
MKRSIYDDDHEAFRDSVREFLERSVIPQVEQHAADKAIPRDFWTEAGRQGFLGLEIPEEYGGAEAGDYRFNAVLLEELNK
VNAALGSCVGIHADITAPYLVELGTDEQKQRWLPGVAAGEVLLAIGMTEPSGGSDLAALKTTAVKDGDSWVINGSKTFIT
NGYSADLVLVAARTSPEKKARGITLFAVESTAPGYSRGRKLDKIGQDESDTAELFFENVRVTDAEIVGELDGGFIHMMQK
LPQERLGCAISNVAHAKQILLETLQYAKDRKAFGQGIGSFQYNKFLLAELFTRIEVTEAFIDQCVVAHAAGELTPIDAAK
AKWWSSQVQNEVLDHCVQLHGGYGYMNEYRVARAWRDARVSKIWAGSNEIMKELIGRDLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=44.5910290237467, Blast_Score=325, Evalue=6e-89,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=33.3333333333333, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=35.2941176470588, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=31.7204301075269, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=29.9465240641711, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=31.7708333333333, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=31.7708333333333, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=30.3191489361702, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=30.4461942257218, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=30.4461942257218, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=30.0791556728232, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=27.8947368421053, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=28.6516853932584, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI211971008, Length=392, Percent_Identity=25.2551020408163, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI48976061, Length=392, Percent_Identity=25.2551020408163, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI38505218, Length=279, Percent_Identity=24.3727598566308, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=30.9711286089239, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=28.6096256684492, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87081702, Length=371, Percent_Identity=24.7978436657682, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082384, Length=296, Percent_Identity=26.6891891891892, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=34.1333333333333, Blast_Score=238, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=32.6315789473684, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17508101, Length=363, Percent_Identity=33.8842975206612, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=33.1550802139037, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=31.9672131147541, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=32.8877005347594, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=31.496062992126, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=30.1837270341207, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=31.3984168865435, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=36.3309352517986, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=35.9307359307359, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=346, Percent_Identity=29.4797687861272, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=31.6363636363636, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=271, Percent_Identity=29.520295202952, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=22.5806451612903, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=27.1966527196653, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=24.9134948096886, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=271, Percent_Identity=25.830258302583, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=271, Percent_Identity=25.830258302583, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=32.6315789473684, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=31.0160427807487, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=29.3010752688172, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=29.8941798941799, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=31.8421052631579, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=31.2865497076023, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=26.7195767195767, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24652780, Length=303, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41976; Mature: 41976

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSIYDDDHEAFRDSVREFLERSVIPQVEQHAADKAIPRDFWTEAGRQGFLGLEIPEEY
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCCEECCCCHHH
GGAEAGDYRFNAVLLEELNKVNAALGSCVGIHADITAPYLVELGTDEQKQRWLPGVAAGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCHHHHHCCCCCHHCC
VLLAIGMTEPSGGSDLAALKTTAVKDGDSWVINGSKTFITNGYSADLVLVAARTSPEKKA
EEEEEECCCCCCCCCHHHHHHHEEECCCCEEECCCEEEEECCCCCCEEEEEECCCCHHHH
RGITLFAVESTAPGYSRGRKLDKIGQDESDTAELFFENVRVTDAEIVGELDGGFIHMMQK
CCEEEEEEECCCCCHHHCCCHHHCCCCCCHHHHHHHHHCCEEHHHHHHCCCCHHHHHHHH
LPQERLGCAISNVAHAKQILLETLQYAKDRKAFGQGIGSFQYNKFLLAELFTRIEVTEAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IDQCVVAHAAGELTPIDAAKAKWWSSQVQNEVLDHCVQLHGGYGYMNEYRVARAWRDARV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SKIWAGSNEIMKELIGRDLGL
HHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRSIYDDDHEAFRDSVREFLERSVIPQVEQHAADKAIPRDFWTEAGRQGFLGLEIPEEY
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCCEECCCCHHH
GGAEAGDYRFNAVLLEELNKVNAALGSCVGIHADITAPYLVELGTDEQKQRWLPGVAAGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCHHHHHCCCCCHHCC
VLLAIGMTEPSGGSDLAALKTTAVKDGDSWVINGSKTFITNGYSADLVLVAARTSPEKKA
EEEEEECCCCCCCCCHHHHHHHEEECCCCEEECCCEEEEECCCCCCEEEEEECCCCHHHH
RGITLFAVESTAPGYSRGRKLDKIGQDESDTAELFFENVRVTDAEIVGELDGGFIHMMQK
CCEEEEEEECCCCCHHHCCCHHHCCCCCCHHHHHHHHHCCEEHHHHHHCCCCHHHHHHHH
LPQERLGCAISNVAHAKQILLETLQYAKDRKAFGQGIGSFQYNKFLLAELFTRIEVTEAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IDQCVVAHAAGELTPIDAAKAKWWSSQVQNEVLDHCVQLHGGYGYMNEYRVARAWRDARV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SKIWAGSNEIMKELIGRDLGL
HHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]