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The map label for this gene is acdA [H]

Identifier: 119714508

GI number: 119714508

Start: 254151

End: 255320

Strand: Reverse

Name: acdA [H]

Synonym: Noca_0241

Alternate gene names: 119714508

Gene position: 255320-254151 (Counterclockwise)

Preceding gene: 119714512

Following gene: 119714507

Centisome position: 5.12

GC content: 73.42

Gene sequence:

>1170_bases
ATGTCCGCATCGCGCCTGCTGCCCACCGACGAGGCCGTCGACCTGATCGCACTCGTCCGCCAGATCGCCGCCGAGGAGCT
GGCACCACGCTCGGCCGAGGCCGAGGCCACCGAGACCTTCCCGCGCGACGTCTTCGCGATGCTGGGCCGGACCGGCCTGC
TCGGCCTCCCCTACCCCGAGCAGCACGGTGGCGGCGGCCAGCCGTACGAGGTCTACCTGCAGGTCCTCGAGGAGGTCGGC
GCGGTCTGGGCGAGCATCGGCGTCGGGATCTCCGTGCACGCCCTGAGCTGCTTCGGCCTCGCGACCGCCGGCACCGCGGC
CCAGCAGGCCGAGTGGCTGCCGGCGATGCTCGGCGGCGAGCTGCTCGGGGCCTATTGCCTCTCCGAGCCGCACGCCGGAT
CCGACCCGGCCGCGATGCGCACCCGGGCCCGCCGCGACGGCGATGAGTACGTCCTCAACGGCGCGAAGGCCTGGACCACC
CACGGAGGGCACGCCGACTTCTACAAGGTGATGGCGCGCACCGGCGACCAGCGCGGCGACATCTCCTGCTTCCTGGTGCC
TGCCGACACCCCGGGCCTGTCCGCCGACCCGCCCGAGCACAAGATGGGGCTGACCGGGTCGGCGACCGCGACGATGCGCT
TCGACGACGTGCGGATCCCGGCCGAGCGGCTCCTGGGCGGCGAGGGCGACGGCCTCAAGATCGCGCTGGCCGGCCTGGAC
GCGGGCCGGCTCGGCATCGCCGCCGTCGCGACCGGGCTCGCCCAAGGTGCCCTCGACCGCGCGGTCGCCTACGCCCAGGA
GCGAGAGACGTTCGGCAGGCGGATCATCGACCACCAGGGCCTGGCGTTCGTGCTGGCCGACATGGAGGCGGCCGTGCAGT
CCGCCCGCGCCACGACCCTCCACGCCGCGCGGCTCAAGGACGCCGGGCTGCCGTACGGCCGCGAGGCCTCGGTCGCCAAG
CTGGTCGCCACCGACAACGCGATGCGGGTGACCACCGACGCCGTCCAGGTGCTCGGGGGCTACGGCTACACCCGGGACTT
CCCGGTCGAGCGCTACATGCGCGAGGCGAAGGTGATGCAGATCTTCGAGGGCACCAACCAGATCCAGCGGATGGTGATCT
CGCGCGCCCTGGACCGCAGCACCGCCGGCACCCTCACCGTCGCACCGTGA

Upstream 100 bases:

>100_bases
CCTCGGCGAGGAACAGCTCGATCAGCTCGTCGAGGAGCTGATGGCGCGGGGGTGGCACGGCGTTGACGCTATCAGTACCA
GGCAGCGTACCTTGGTACTC

Downstream 100 bases:

>100_bases
CCGCCCGCCGCTGACCACCCGCCGCTGGCCGCCCGCGCCTGGCCGCCCGCGCCTGATCGCCCGCCCCTGACCACTCGCTC
AGCGTCGACGCGCACCTCAG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSASRLLPTDEAVDLIALVRQIAAEELAPRSAEAEATETFPRDVFAMLGRTGLLGLPYPEQHGGGGQPYEVYLQVLEEVG
AVWASIGVGISVHALSCFGLATAGTAAQQAEWLPAMLGGELLGAYCLSEPHAGSDPAAMRTRARRDGDEYVLNGAKAWTT
HGGHADFYKVMARTGDQRGDISCFLVPADTPGLSADPPEHKMGLTGSATATMRFDDVRIPAERLLGGEGDGLKIALAGLD
AGRLGIAAVATGLAQGALDRAVAYAQERETFGRRIIDHQGLAFVLADMEAAVQSARATTLHAARLKDAGLPYGREASVAK
LVATDNAMRVTTDAVQVLGGYGYTRDFPVERYMREAKVMQIFEGTNQIQRMVISRALDRSTAGTLTVAP

Sequences:

>Translated_389_residues
MSASRLLPTDEAVDLIALVRQIAAEELAPRSAEAEATETFPRDVFAMLGRTGLLGLPYPEQHGGGGQPYEVYLQVLEEVG
AVWASIGVGISVHALSCFGLATAGTAAQQAEWLPAMLGGELLGAYCLSEPHAGSDPAAMRTRARRDGDEYVLNGAKAWTT
HGGHADFYKVMARTGDQRGDISCFLVPADTPGLSADPPEHKMGLTGSATATMRFDDVRIPAERLLGGEGDGLKIALAGLD
AGRLGIAAVATGLAQGALDRAVAYAQERETFGRRIIDHQGLAFVLADMEAAVQSARATTLHAARLKDAGLPYGREASVAK
LVATDNAMRVTTDAVQVLGGYGYTRDFPVERYMREAKVMQIFEGTNQIQRMVISRALDRSTAGTLTVAP
>Mature_388_residues
SASRLLPTDEAVDLIALVRQIAAEELAPRSAEAEATETFPRDVFAMLGRTGLLGLPYPEQHGGGGQPYEVYLQVLEEVGA
VWASIGVGISVHALSCFGLATAGTAAQQAEWLPAMLGGELLGAYCLSEPHAGSDPAAMRTRARRDGDEYVLNGAKAWTTH
GGHADFYKVMARTGDQRGDISCFLVPADTPGLSADPPEHKMGLTGSATATMRFDDVRIPAERLLGGEGDGLKIALAGLDA
GRLGIAAVATGLAQGALDRAVAYAQERETFGRRIIDHQGLAFVLADMEAAVQSARATTLHAARLKDAGLPYGREASVAKL
VATDNAMRVTTDAVQVLGGYGYTRDFPVERYMREAKVMQIFEGTNQIQRMVISRALDRSTAGTLTVAP

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=42.8184281842818, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=39.4101876675603, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI187960098, Length=372, Percent_Identity=38.7096774193548, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI4557231, Length=372, Percent_Identity=38.7096774193548, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI226958412, Length=392, Percent_Identity=34.9489795918367, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=35.978835978836, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI226958414, Length=382, Percent_Identity=33.5078534031414, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=35, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI76496475, Length=355, Percent_Identity=34.0845070422535, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI4557235, Length=355, Percent_Identity=34.0845070422535, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI4501857, Length=365, Percent_Identity=32.0547945205479, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI4503943, Length=374, Percent_Identity=31.5508021390374, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI7669494, Length=360, Percent_Identity=31.3888888888889, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI38505218, Length=299, Percent_Identity=29.0969899665552, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=28.3737024221453, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=28.3737024221453, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=29.4429708222812, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=27.4406332453826, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87082384, Length=266, Percent_Identity=28.1954887218045, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=36.9973190348526, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17569725, Length=362, Percent_Identity=37.292817679558, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=37.5, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=35.3723404255319, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=36.5122615803815, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=35.3723404255319, Blast_Score=245, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=34.7708894878706, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=378, Percent_Identity=33.3333333333333, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=38.9891696750903, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17551932, Length=361, Percent_Identity=30.1939058171745, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=365, Percent_Identity=31.2328767123288, Blast_Score=174, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=30.1075268817204, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71985192, Length=325, Percent_Identity=32, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=37.117903930131, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=30.0411522633745, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=266, Percent_Identity=29.6992481203008, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=339, Percent_Identity=26.8436578171091, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17531913, Length=186, Percent_Identity=29.0322580645161, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646207, Length=364, Percent_Identity=40.3846153846154, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=40.0544959128065, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=38.1818181818182, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=34.2710997442455, Blast_Score=244, Evalue=5e-65,
Organism=Drosophila melanogaster, GI21355753, Length=363, Percent_Identity=35.5371900826446, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=34.3195266272189, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI19920834, Length=374, Percent_Identity=31.283422459893, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI221473076, Length=360, Percent_Identity=24.4444444444444, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550141, Length=360, Percent_Identity=24.4444444444444, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41169; Mature: 41038

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASRLLPTDEAVDLIALVRQIAAEELAPRSAEAEATETFPRDVFAMLGRTGLLGLPYPE
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
QHGGGGQPYEVYLQVLEEVGAVWASIGVGISVHALSCFGLATAGTAAQQAEWLPAMLGGE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLGAYCLSEPHAGSDPAAMRTRARRDGDEYVLNGAKAWTTHGGHADFYKVMARTGDQRGD
HHHHHHHCCCCCCCCHHHHHHHHHCCCCHHEECCCCEECCCCCCHHHHHHHHHCCCCCCC
ISCFLVPADTPGLSADPPEHKMGLTGSATATMRFDDVRIPAERLLGGEGDGLKIALAGLD
EEEEEEECCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEEECC
AGRLGIAAVATGLAQGALDRAVAYAQERETFGRRIIDHQGLAFVLADMEAAVQSARATTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HAARLKDAGLPYGREASVAKLVATDNAMRVTTDAVQVLGGYGYTRDFPVERYMREAKVMQ
HHHHHHHCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
IFEGTNQIQRMVISRALDRSTAGTLTVAP
HHHHHHHHHHHHHHHHHCCCCCCCEEECC
>Mature Secondary Structure 
SASRLLPTDEAVDLIALVRQIAAEELAPRSAEAEATETFPRDVFAMLGRTGLLGLPYPE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
QHGGGGQPYEVYLQVLEEVGAVWASIGVGISVHALSCFGLATAGTAAQQAEWLPAMLGGE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLGAYCLSEPHAGSDPAAMRTRARRDGDEYVLNGAKAWTTHGGHADFYKVMARTGDQRGD
HHHHHHHCCCCCCCCHHHHHHHHHCCCCHHEECCCCEECCCCCCHHHHHHHHHCCCCCCC
ISCFLVPADTPGLSADPPEHKMGLTGSATATMRFDDVRIPAERLLGGEGDGLKIALAGLD
EEEEEEECCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEEECC
AGRLGIAAVATGLAQGALDRAVAYAQERETFGRRIIDHQGLAFVLADMEAAVQSARATTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HAARLKDAGLPYGREASVAKLVATDNAMRVTTDAVQVLGGYGYTRDFPVERYMREAKVMQ
HHHHHHHCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
IFEGTNQIQRMVISRALDRSTAGTLTVAP
HHHHHHHHHHHHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]