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The map label for this gene is dmpD [H]

Identifier: 119714475

GI number: 119714475

Start: 223704

End: 224579

Strand: Direct

Name: dmpD [H]

Synonym: Noca_0208

Alternate gene names: 119714475

Gene position: 223704-224579 (Clockwise)

Preceding gene: 119714474

Following gene: 119714476

Centisome position: 4.49

GC content: 70.43

Gene sequence:

>876_bases
GTGACCGCAGTCGCCCCGGCACCGGTGGAGCGCTCCGGGATCCGCGAGTCCGACGTCGCGATCGCCGGCGGCCGGCACCT
GCGGGTGCTGGAGGCCGGCGAGCCCGGGATGCCGGCCCTGCTCTTCCTGCACGGCTCCGGCCCGGGCGTGACCGCCCGGG
CGAACTGGGAGAACGTGATGGCCGGCCTCGGAGACCGGTTCCACTGCATCGCGCCGGACATCCTCGGGTTCGGCGAGTCC
AGCCACGCCGACCCGCAACCGCAGGGCTTCAAGGCGAACGCCGAGGTCCGCATCGACGCGCTGCTCCAGATGCTCGACGC
CCTCGGTGTCTCGCGGGTGACCGTGGTCGGCAACTCGATGGGCGGCATGTACTCGCTGCGGCTGTGCCAGCTGCGCCCCG
ACCTCGTCGAGAAGATGGTGCTGATGGGCTCGGGCGGCATGCCCGGGCTCGCTCCGACACCCCAGCTGATCAAGCTGGTC
ACGTTCTTCGACGACCCGTCGCTCGAGGCGATGACCGCGCTGCTCACCGAGTTCGTGCACGACAAGACCGCCTTCGGCGA
TCGGATCGAGGACTTCGCCGCCGGCCGGATGGCCCTGGTCACCCGGCCCGAGATCGAGACCGCGCACCGCGCCATGTTCG
GCGAGGGGGAGATGCTCAGCTTCTCCCCGGCCGAGCTCGCGAGGCTCGACGTACCGACCCTGGTCGTGCATGGCCGCCAA
GACGTGATCGTGCCGATCGAGTGCAGCCTCTACCTCGCCGAGCACCTGCCGCAGGCCGACCTGTACGTGATGAACAACTG
CGGGCACTGGACCCAGGTCGAGCAGCCCGACCGGTTCCGCACGATCCTGCGTGACTTCGCCGACGGCCGGCTCTGA

Upstream 100 bases:

>100_bases
GTACCCACGACGTGCCGAGCATCTGGGGCCACCACCGCTCGCAGGCCTACCTCGACGGCCCTCCCGGAATCTTCCAGATG
CTCGACGCGGAGGCCCCGGC

Downstream 100 bases:

>100_bases
CCGTCCCCCACCTGACCCCGAACGGGAGCTTCGTCATGACCCTTGCCGAGAAGGCGCGCGCCGCCGCGCCCGTCCTCGCC
GCCAGCGACGCCGAGAGCGG

Product: alpha/beta hydrolase fold protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTAVAPAPVERSGIRESDVAIAGGRHLRVLEAGEPGMPALLFLHGSGPGVTARANWENVMAGLGDRFHCIAPDILGFGES
SHADPQPQGFKANAEVRIDALLQMLDALGVSRVTVVGNSMGGMYSLRLCQLRPDLVEKMVLMGSGGMPGLAPTPQLIKLV
TFFDDPSLEAMTALLTEFVHDKTAFGDRIEDFAAGRMALVTRPEIETAHRAMFGEGEMLSFSPAELARLDVPTLVVHGRQ
DVIVPIECSLYLAEHLPQADLYVMNNCGHWTQVEQPDRFRTILRDFADGRL

Sequences:

>Translated_291_residues
MTAVAPAPVERSGIRESDVAIAGGRHLRVLEAGEPGMPALLFLHGSGPGVTARANWENVMAGLGDRFHCIAPDILGFGES
SHADPQPQGFKANAEVRIDALLQMLDALGVSRVTVVGNSMGGMYSLRLCQLRPDLVEKMVLMGSGGMPGLAPTPQLIKLV
TFFDDPSLEAMTALLTEFVHDKTAFGDRIEDFAAGRMALVTRPEIETAHRAMFGEGEMLSFSPAELARLDVPTLVVHGRQ
DVIVPIECSLYLAEHLPQADLYVMNNCGHWTQVEQPDRFRTILRDFADGRL
>Mature_290_residues
TAVAPAPVERSGIRESDVAIAGGRHLRVLEAGEPGMPALLFLHGSGPGVTARANWENVMAGLGDRFHCIAPDILGFGESS
HADPQPQGFKANAEVRIDALLQMLDALGVSRVTVVGNSMGGMYSLRLCQLRPDLVEKMVLMGSGGMPGLAPTPQLIKLVT
FFDDPSLEAMTALLTEFVHDKTAFGDRIEDFAAGRMALVTRPEIETAHRAMFGEGEMLSFSPAELARLDVPTLVVHGRQD
VIVPIECSLYLAEHLPQADLYVMNNCGHWTQVEQPDRFRTILRDFADGRL

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=281, Percent_Identity=29.8932384341637, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 31557; Mature: 31426

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAPAPVERSGIRESDVAIAGGRHLRVLEAGEPGMPALLFLHGSGPGVTARANWENVM
CCCCCCCCCHHCCCCCCCEEEECCCEEEEEECCCCCCCEEEEEECCCCCEEEECCHHHHH
AGLGDRFHCIAPDILGFGESSHADPQPQGFKANAEVRIDALLQMLDALGVSRVTVVGNSM
HHCCCCEEEECHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEEECCC
GGMYSLRLCQLRPDLVEKMVLMGSGGMPGLAPTPQLIKLVTFFDDPSLEAMTALLTEFVH
CCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHEEEHHCCCCCHHHHHHHHHHHHH
DKTAFGDRIEDFAAGRMALVTRPEIETAHRAMFGEGEMLSFSPAELARLDVPTLVVHGRQ
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEECHHHHHHCCCCEEEEECCC
DVIVPIECSLYLAEHLPQADLYVMNNCGHWTQVEQPDRFRTILRDFADGRL
CEEEEEEHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAVAPAPVERSGIRESDVAIAGGRHLRVLEAGEPGMPALLFLHGSGPGVTARANWENVM
CCCCCCCCHHCCCCCCCEEEECCCEEEEEECCCCCCCEEEEEECCCCCEEEECCHHHHH
AGLGDRFHCIAPDILGFGESSHADPQPQGFKANAEVRIDALLQMLDALGVSRVTVVGNSM
HHCCCCEEEECHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEEECCC
GGMYSLRLCQLRPDLVEKMVLMGSGGMPGLAPTPQLIKLVTFFDDPSLEAMTALLTEFVH
CCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHEEEHHCCCCCHHHHHHHHHHHHH
DKTAFGDRIEDFAAGRMALVTRPEIETAHRAMFGEGEMLSFSPAELARLDVPTLVVHGRQ
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEECHHHHHHCCCCEEEEECCC
DVIVPIECSLYLAEHLPQADLYVMNNCGHWTQVEQPDRFRTILRDFADGRL
CEEEEEEHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]