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The map label for this gene is qorA [H]

Identifier: 119714447

GI number: 119714447

Start: 192241

End: 193218

Strand: Reverse

Name: qorA [H]

Synonym: Noca_0180

Alternate gene names: 119714447

Gene position: 193218-192241 (Counterclockwise)

Preceding gene: 119714448

Following gene: 119714446

Centisome position: 3.88

GC content: 74.34

Gene sequence:

>978_bases
ATGCGTGCCGTGATCGCCACCGGGGCCGGGGGCCCCGACGTCTTGTCCGTCGCCGAGCTCCCCGACCCCGAGCCCGGTCC
CGGCGAGGTCCTGCTCGCGGTCGCGGCCGCGGGCCTCAACCGGGCCGACCTGCTGCAGCGGCAGGGCTTCTACCCGCCAC
CGCCCGGCGCGTCCGACGTGATCGGCATGGAGTGCAGTGGCACGGTCGCCGCGCTCGGCGAGGGCGTCGAGGGGTGGGCG
GTCGGCGACCCGGCGTGCGCCCTGCTCGCCGGGGGCGGGTACGCCGAGCTGGTCGCCGTACCGTCCGGGCAGCTGATGCC
GGTGCCCGACGGCGTCGACCTGGTGACCGCCGCCGCGCTGCCCGAGGTGGCCTGCACGGTGTGGTCGAACGTGTTCATGC
TCGGCGGCCTCAAGCCCGGCGAGGCGTTCTTGGTGCACGGCGGCGCCGGCGGCATCGGGACGTTCGCGATCCAGCTCGCG
CACCAGCTCGGCGCGCAGGTCCTCACGACGGCCGGCACCGCCGAGAAGCGCGCCGCGTGCGCGGCCCTCGGTGCCGACGT
CACGATCGACTACCGCGACCAGGACTTCGTCGAAGTGGCTCGGGCCGCGACCGAGGGGCGGGGCGTGGACCTGGTCCTCG
ACAACATGGGCGCGAAGTACCTCGACCGCAACCTGGACGCCCTGGCCACCGAGGGCCGGCTGGTGATCATCGGGATGCAG
GGCGGCACCCGGGCCGAGCTCGACATCAACAAGCTGCTGCGCAAGCGCGGGGCGATCATCGCCACCACCCTGCGGGCCCG
CCCCACCGAGGAGAAGTCGGCGATCTGCGCCTCCGTCGTCGAGCACGTGTGGCCGCTGGTGGCCGAGGGTCTCGTCCGGC
CGGTCGTGCACGGCACCATGCCGTTGGCCGAGGCCGGCGCCGCCCACGCGCTGATGGAGTCCGGCGAGCACAGCGGGAAG
ATCCTGCTCACCGTCTGA

Upstream 100 bases:

>100_bases
GTCGTGGACCACACCGGCGACGTCTTCGAGGACGAGAACGCCGGGGCCGACGAGGAGGAGTGACCTCGGGGTCCCGCGCG
CCGGCTCCTAGGCTGGCCGC

Downstream 100 bases:

>100_bases
ATGCGCGGCTCGGGCGGATACGGTGGACCCCATGAACGAGCAGCCCGGACAGGACGAGCAGGAGCAGCAGGTCGTGATCA
TCGGCCCCGACGGCCACCCG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRAVIATGAGGPDVLSVAELPDPEPGPGEVLLAVAAAGLNRADLLQRQGFYPPPPGASDVIGMECSGTVAALGEGVEGWA
VGDPACALLAGGGYAELVAVPSGQLMPVPDGVDLVTAAALPEVACTVWSNVFMLGGLKPGEAFLVHGGAGGIGTFAIQLA
HQLGAQVLTTAGTAEKRAACAALGADVTIDYRDQDFVEVARAATEGRGVDLVLDNMGAKYLDRNLDALATEGRLVIIGMQ
GGTRAELDINKLLRKRGAIIATTLRARPTEEKSAICASVVEHVWPLVAEGLVRPVVHGTMPLAEAGAAHALMESGEHSGK
ILLTV

Sequences:

>Translated_325_residues
MRAVIATGAGGPDVLSVAELPDPEPGPGEVLLAVAAAGLNRADLLQRQGFYPPPPGASDVIGMECSGTVAALGEGVEGWA
VGDPACALLAGGGYAELVAVPSGQLMPVPDGVDLVTAAALPEVACTVWSNVFMLGGLKPGEAFLVHGGAGGIGTFAIQLA
HQLGAQVLTTAGTAEKRAACAALGADVTIDYRDQDFVEVARAATEGRGVDLVLDNMGAKYLDRNLDALATEGRLVIIGMQ
GGTRAELDINKLLRKRGAIIATTLRARPTEEKSAICASVVEHVWPLVAEGLVRPVVHGTMPLAEAGAAHALMESGEHSGK
ILLTV
>Mature_325_residues
MRAVIATGAGGPDVLSVAELPDPEPGPGEVLLAVAAAGLNRADLLQRQGFYPPPPGASDVIGMECSGTVAALGEGVEGWA
VGDPACALLAGGGYAELVAVPSGQLMPVPDGVDLVTAAALPEVACTVWSNVFMLGGLKPGEAFLVHGGAGGIGTFAIQLA
HQLGAQVLTTAGTAEKRAACAALGADVTIDYRDQDFVEVARAATEGRGVDLVLDNMGAKYLDRNLDALATEGRLVIIGMQ
GGTRAELDINKLLRKRGAIIATTLRARPTEEKSAICASVVEHVWPLVAEGLVRPVVHGTMPLAEAGAAHALMESGEHSGK
ILLTV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=334, Percent_Identity=44.6107784431138, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI22538444, Length=334, Percent_Identity=44.6107784431138, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=30.6122448979592, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI18379349, Length=343, Percent_Identity=30.0291545189504, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=27.355623100304, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=27.355623100304, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=31.629392971246, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI28557745, Length=272, Percent_Identity=30.5147058823529, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=25.2279635258359, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI47519420, Length=347, Percent_Identity=27.0893371757925, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI197927207, Length=193, Percent_Identity=27.979274611399, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=31.974921630094, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1788073, Length=288, Percent_Identity=26.7361111111111, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI226510941, Length=327, Percent_Identity=27.217125382263, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=328, Percent_Identity=28.9634146341463, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=309, Percent_Identity=28.4789644012945, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71987554, Length=188, Percent_Identity=32.4468085106383, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=333, Percent_Identity=28.2282282282282, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=352, Percent_Identity=24.7159090909091, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324486, Length=282, Percent_Identity=25.531914893617, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=23.9644970414201, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=221, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581345, Length=233, Percent_Identity=30.0429184549356, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920632, Length=242, Percent_Identity=28.9256198347107, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221330659, Length=242, Percent_Identity=28.9256198347107, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33055; Mature: 33055

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVIATGAGGPDVLSVAELPDPEPGPGEVLLAVAAAGLNRADLLQRQGFYPPPPGASDV
CCEEEECCCCCCCEEEECCCCCCCCCCCCEEEEHHHCCCCHHHHHHHCCCCCCCCCCCCE
IGMECSGTVAALGEGVEGWAVGDPACALLAGGGYAELVAVPSGQLMPVPDGVDLVTAAAL
EEECCCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCEEECCCCCHHHHHHHH
PEVACTVWSNVFMLGGLKPGEAFLVHGGAGGIGTFAIQLAHQLGAQVLTTAGTAEKRAAC
HHHHHHHHHHHHEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AALGADVTIDYRDQDFVEVARAATEGRGVDLVLDNMGAKYLDRNLDALATEGRLVIIGMQ
HHCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCHHHCCCCEEEEEECC
GGTRAELDINKLLRKRGAIIATTLRARPTEEKSAICASVVEHVWPLVAEGLVRPVVHGTM
CCCEECCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLAEAGAAHALMESGEHSGKILLTV
CHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MRAVIATGAGGPDVLSVAELPDPEPGPGEVLLAVAAAGLNRADLLQRQGFYPPPPGASDV
CCEEEECCCCCCCEEEECCCCCCCCCCCCEEEEHHHCCCCHHHHHHHCCCCCCCCCCCCE
IGMECSGTVAALGEGVEGWAVGDPACALLAGGGYAELVAVPSGQLMPVPDGVDLVTAAAL
EEECCCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCEEECCCCCHHHHHHHH
PEVACTVWSNVFMLGGLKPGEAFLVHGGAGGIGTFAIQLAHQLGAQVLTTAGTAEKRAAC
HHHHHHHHHHHHEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AALGADVTIDYRDQDFVEVARAATEGRGVDLVLDNMGAKYLDRNLDALATEGRLVIIGMQ
HHCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCHHHCCCCEEEEEECC
GGTRAELDINKLLRKRGAIIATTLRARPTEEKSAICASVVEHVWPLVAEGLVRPVVHGTM
CCCEECCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLAEAGAAHALMESGEHSGKILLTV
CHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]