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The map label for this gene is recQ [H]

Identifier: 119714400

GI number: 119714400

Start: 146475

End: 148619

Strand: Direct

Name: recQ [H]

Synonym: Noca_0133

Alternate gene names: 119714400

Gene position: 146475-148619 (Clockwise)

Preceding gene: 119714398

Following gene: 119714401

Centisome position: 2.94

GC content: 74.83

Gene sequence:

>2145_bases
GTGAGTGCCCCAGCCGAGACCGACGTACGCCGCAGCGCGGAGGCGCACCTGCGCGCGCTCGTCGGGCCGCGGCCGGGTGA
GCCGGAGCCGGTGCTGCGCGAGGACCAGTGGGCCGCGATCGAGGCGCTCGCCGTGCACCGCCGCCGGGCGCTCGTTGTGC
AGCGCACCGGCTGGGGCAAGTCCGCGGTCTACTTCGTGGCGACGCTGTTGCTGCGCGAGCAGGGTGCCGGGCCGACGGTC
ATCGTCTCCCCGCTGCTGGCCCTGATGCGCAACCAGATCGCGGCGGCCGAGCGGGCCGGGATCCGCGCGGTGACGATCAA
CTCCACCAACATCGAGGACTGGGAGCCGATCCACGAGGCGATCGCGGCCGGCGAGGTCGACGTGCTGCTGGTCAGTCCCG
AGCGGCTCAACAACCCGGGCTTCCGCGACGAGGTGCTGCCCCGGCTGGCCGCGACCTGCGGCCTCCTGGTCGTCGACGAG
GCGCATTGCATCTCCGACTGGGGCCACGACTTCCGGCCCGACTACCGTCGGATCCGCACCCTGCTGGGCGAGCTCCCCGA
CGGCATCCCGGTGCTCGCGACCACCGCGACCGCCAACGCCCGGGTCACCGACGACGTCGCCGAGCAGCTCGGGGTCTCGA
CGGGCTCGGCCACCGACGGCTTCGGCGAGGTCCTGGTGCTGCGCGGTTCGCTGGACCGCGAGTCGCTGCGCCTCGGCGTG
GTCCGGCTCCGGACCGCGGAGCAGCGGTTGGCCTGGCTCGCCGACCACCTCGCCGAGCAGCCCGGGTCCGGCATCGTCTA
CTGCCTGACGGTCGCCGCCACCCAGGAGATCGCCGACTACCTGCGCTCGCGCGGCCACGAGGTCGCGGCGTACTCCGGCC
AGACCGACCCGACCGAGCGGCACGCCCTCGAGCAGGACCTGGTGAATGGCCGGGTCAAGGCGCTGGTCGCCACGAGCGCG
CTCGGCATGGGCTTCGACGCCACCCTCGGCTTCGTGGTCAACATGGGCGCGCCGCCCTCGCCGGTCGCCTACTACCAGCA
GGTCGGCCGCGCCGGCCGCGGCACGACTCTGCCGCCGGAGGGGGCGACCGTCGTGCTGCTGCCCGCGATCGAGGACCGCG
ACATCTGGGCCTACTTCGCCTCCCTCGCCTTCCCGCGCGAGGAGCAGGTCCGCCGCACGCTCGAGGTGCTGGGGGCGGAG
GGCCGGCCGCTCAGCACGGCCACCCTGGAGACCTACGTCGACCTCAACCGCACCAGGCTGGAGACGATGCTCAAGGTGCT
CGACGTCGACGGCGCCGTACGCCGGGTCCGCGGCGGCTGGGAGGCCACCGGTCGCGAGTGGTCCTACGACGAGGAGCGCT
ACCGCCGGGTGACCGAGGCGCGCCAGCGCGAGCAGCAGGCTATGCTCGACTACATCGCGACCGACGCCTGCCGGATGCGG
TTCCTGCGCGACCAGCTCGACGACCCGGAAGCCGAGGACTGCGGGCGCTGCGACAACTGCGGCGGGCTCACCCTCTCCGC
CGACGTCTCGGCCGCCGCGCTCGAGGACGCCGGCGCCCGGCTGGCCCGGCCCGGGGTCGCCGTCGAGCCGCGGAAGATGT
GGCCGAGCGCGCTGGCCAACCTCGGCATCGAGCTCAAGGGCAAGATCGCCGAGGGCGCCCAGGAGGGCCGGGCGGTGGCC
CGGCTCACCGACCTCGGCCACGGCCAGGCGCTGCGCGAGCTCTTCGCGCCGGCGACCCCGGACGGCCCGGTCCCGGTGCC
GTTGGTCCGCGCGGTCCTCGAGGTGCTCGGTGACTGGCGGCCCCCGGTCGACGCGATCGTGGTCGTCGAGTCGCAGACCC
GGCCCACGCTGACGGCCGACCTGGCCGCCGGCCTGTCCCGCCACCTCGGGGTCCCCGTGGTGGGACGGTGGGCGATCGTC
AACCCCGACATCGTCCCCGGCCAGGGGGCCGCCAACTCCGCGCAGCGGGTCGCCGCCGTCGGGCGGCGCTTCGCCCTCCA
GGTCGACCAGCCGCTGGACGGGCTGCGGGTGCTGCTCGTCGACGACCGCACCGACACCGGATGGACGCTGACCCTGGCGG
CTCGCGCCGTACGCCGCGCCGGCGCCGCGGAGGTCCGACCGCTGGTCCTCGCCACCACCACCTGA

Upstream 100 bases:

>100_bases
CCGCCCGTACGAGTCGCGTCGGACCTCAGGAGGGCGGCGGAGCGCTCCAGATACCCGTCCGCGGAGGACGTTGTCGGGGC
CCGCTGGTAGACAGGGTCGG

Downstream 100 bases:

>100_bases
GCCGGCCGCGCCCGAACCGAGCCGGGCCGGCTGAGCCGGGTGCCCGCCCGGCGCTGCGGGACGTCGTACGGGGCGGTCGT
CGGGGCAGCCGGATCGGATG

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSAPAETDVRRSAEAHLRALVGPRPGEPEPVLREDQWAAIEALAVHRRRALVVQRTGWGKSAVYFVATLLLREQGAGPTV
IVSPLLALMRNQIAAAERAGIRAVTINSTNIEDWEPIHEAIAAGEVDVLLVSPERLNNPGFRDEVLPRLAATCGLLVVDE
AHCISDWGHDFRPDYRRIRTLLGELPDGIPVLATTATANARVTDDVAEQLGVSTGSATDGFGEVLVLRGSLDRESLRLGV
VRLRTAEQRLAWLADHLAEQPGSGIVYCLTVAATQEIADYLRSRGHEVAAYSGQTDPTERHALEQDLVNGRVKALVATSA
LGMGFDATLGFVVNMGAPPSPVAYYQQVGRAGRGTTLPPEGATVVLLPAIEDRDIWAYFASLAFPREEQVRRTLEVLGAE
GRPLSTATLETYVDLNRTRLETMLKVLDVDGAVRRVRGGWEATGREWSYDEERYRRVTEARQREQQAMLDYIATDACRMR
FLRDQLDDPEAEDCGRCDNCGGLTLSADVSAAALEDAGARLARPGVAVEPRKMWPSALANLGIELKGKIAEGAQEGRAVA
RLTDLGHGQALRELFAPATPDGPVPVPLVRAVLEVLGDWRPPVDAIVVVESQTRPTLTADLAAGLSRHLGVPVVGRWAIV
NPDIVPGQGAANSAQRVAAVGRRFALQVDQPLDGLRVLLVDDRTDTGWTLTLAARAVRRAGAAEVRPLVLATTT

Sequences:

>Translated_714_residues
MSAPAETDVRRSAEAHLRALVGPRPGEPEPVLREDQWAAIEALAVHRRRALVVQRTGWGKSAVYFVATLLLREQGAGPTV
IVSPLLALMRNQIAAAERAGIRAVTINSTNIEDWEPIHEAIAAGEVDVLLVSPERLNNPGFRDEVLPRLAATCGLLVVDE
AHCISDWGHDFRPDYRRIRTLLGELPDGIPVLATTATANARVTDDVAEQLGVSTGSATDGFGEVLVLRGSLDRESLRLGV
VRLRTAEQRLAWLADHLAEQPGSGIVYCLTVAATQEIADYLRSRGHEVAAYSGQTDPTERHALEQDLVNGRVKALVATSA
LGMGFDATLGFVVNMGAPPSPVAYYQQVGRAGRGTTLPPEGATVVLLPAIEDRDIWAYFASLAFPREEQVRRTLEVLGAE
GRPLSTATLETYVDLNRTRLETMLKVLDVDGAVRRVRGGWEATGREWSYDEERYRRVTEARQREQQAMLDYIATDACRMR
FLRDQLDDPEAEDCGRCDNCGGLTLSADVSAAALEDAGARLARPGVAVEPRKMWPSALANLGIELKGKIAEGAQEGRAVA
RLTDLGHGQALRELFAPATPDGPVPVPLVRAVLEVLGDWRPPVDAIVVVESQTRPTLTADLAAGLSRHLGVPVVGRWAIV
NPDIVPGQGAANSAQRVAAVGRRFALQVDQPLDGLRVLLVDDRTDTGWTLTLAARAVRRAGAAEVRPLVLATTT
>Mature_713_residues
SAPAETDVRRSAEAHLRALVGPRPGEPEPVLREDQWAAIEALAVHRRRALVVQRTGWGKSAVYFVATLLLREQGAGPTVI
VSPLLALMRNQIAAAERAGIRAVTINSTNIEDWEPIHEAIAAGEVDVLLVSPERLNNPGFRDEVLPRLAATCGLLVVDEA
HCISDWGHDFRPDYRRIRTLLGELPDGIPVLATTATANARVTDDVAEQLGVSTGSATDGFGEVLVLRGSLDRESLRLGVV
RLRTAEQRLAWLADHLAEQPGSGIVYCLTVAATQEIADYLRSRGHEVAAYSGQTDPTERHALEQDLVNGRVKALVATSAL
GMGFDATLGFVVNMGAPPSPVAYYQQVGRAGRGTTLPPEGATVVLLPAIEDRDIWAYFASLAFPREEQVRRTLEVLGAEG
RPLSTATLETYVDLNRTRLETMLKVLDVDGAVRRVRGGWEATGREWSYDEERYRRVTEARQREQQAMLDYIATDACRMRF
LRDQLDDPEAEDCGRCDNCGGLTLSADVSAAALEDAGARLARPGVAVEPRKMWPSALANLGIELKGKIAEGAQEGRAVAR
LTDLGHGQALRELFAPATPDGPVPVPLVRAVLEVLGDWRPPVDAIVVVESQTRPTLTADLAAGLSRHLGVPVVGRWAIVN
PDIVPGQGAANSAQRVAAVGRRFALQVDQPLDGLRVLLVDDRTDTGWTLTLAARAVRRAGAAEVRPLVLATTT

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI110735439, Length=328, Percent_Identity=31.4024390243902, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI169218196, Length=328, Percent_Identity=31.4024390243902, Blast_Score=146, Evalue=8e-35,
Organism=Homo sapiens, GI4557365, Length=334, Percent_Identity=32.0359281437126, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI51242943, Length=342, Percent_Identity=30.7017543859649, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI51242947, Length=342, Percent_Identity=30.7017543859649, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI148612816, Length=342, Percent_Identity=30.7017543859649, Blast_Score=133, Evalue=7e-31,
Organism=Homo sapiens, GI284005309, Length=343, Percent_Identity=32.9446064139942, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI14591902, Length=324, Percent_Identity=26.5432098765432, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI14591904, Length=324, Percent_Identity=26.5432098765432, Blast_Score=125, Evalue=2e-28,
Organism=Escherichia coli, GI48994977, Length=317, Percent_Identity=35.9621451104101, Blast_Score=161, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71987997, Length=354, Percent_Identity=31.3559322033898, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71987993, Length=354, Percent_Identity=31.3559322033898, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564293, Length=338, Percent_Identity=32.2485207100592, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17552866, Length=333, Percent_Identity=32.7327327327327, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25145561, Length=313, Percent_Identity=30.0319488817891, Blast_Score=130, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6323844, Length=330, Percent_Identity=29.6969696969697, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24646066, Length=312, Percent_Identity=30.4487179487179, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI62472181, Length=321, Percent_Identity=32.0872274143302, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24664230, Length=321, Percent_Identity=32.0872274143302, Blast_Score=126, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24664226, Length=321, Percent_Identity=32.0872274143302, Blast_Score=126, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21358123, Length=334, Percent_Identity=28.4431137724551, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77116; Mature: 76985

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPAETDVRRSAEAHLRALVGPRPGEPEPVLREDQWAAIEALAVHRRRALVVQRTGWGK
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCC
SAVYFVATLLLREQGAGPTVIVSPLLALMRNQIAAAERAGIRAVTINSTNIEDWEPIHEA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHH
IAAGEVDVLLVSPERLNNPGFRDEVLPRLAATCGLLVVDEAHCISDWGHDFRPDYRRIRT
HHCCCEEEEEECHHHCCCCCCHHHHHHHHHHHCCEEEEECHHHHHHCCCCCCHHHHHHHH
LLGELPDGIPVLATTATANARVTDDVAEQLGVSTGSATDGFGEVLVLRGSLDRESLRLGV
HHHHCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHH
VRLRTAEQRLAWLADHLAEQPGSGIVYCLTVAATQEIADYLRSRGHEVAAYSGQTDPTER
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
HALEQDLVNGRVKALVATSALGMGFDATLGFVVNMGAPPSPVAYYQQVGRAGRGTTLPPE
HHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
GATVVLLPAIEDRDIWAYFASLAFPREEQVRRTLEVLGAEGRPLSTATLETYVDLNRTRL
CCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHH
ETMLKVLDVDGAVRRVRGGWEATGREWSYDEERYRRVTEARQREQQAMLDYIATDACRMR
HHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLRDQLDDPEAEDCGRCDNCGGLTLSADVSAAALEDAGARLARPGVAVEPRKMWPSALAN
HHHHHCCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHH
LGIELKGKIAEGAQEGRAVARLTDLGHGQALRELFAPATPDGPVPVPLVRAVLEVLGDWR
CCCEEECCHHHCHHHCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
PPVDAIVVVESQTRPTLTADLAAGLSRHLGVPVVGRWAIVNPDIVPGQGAANSAQRVAAV
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECEEEEECCCCCCCCCCCCHHHHHHHH
GRRFALQVDQPLDGLRVLLVDDRTDTGWTLTLAARAVRRAGAAEVRPLVLATTT
HHHEEEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure 
SAPAETDVRRSAEAHLRALVGPRPGEPEPVLREDQWAAIEALAVHRRRALVVQRTGWGK
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCC
SAVYFVATLLLREQGAGPTVIVSPLLALMRNQIAAAERAGIRAVTINSTNIEDWEPIHEA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHH
IAAGEVDVLLVSPERLNNPGFRDEVLPRLAATCGLLVVDEAHCISDWGHDFRPDYRRIRT
HHCCCEEEEEECHHHCCCCCCHHHHHHHHHHHCCEEEEECHHHHHHCCCCCCHHHHHHHH
LLGELPDGIPVLATTATANARVTDDVAEQLGVSTGSATDGFGEVLVLRGSLDRESLRLGV
HHHHCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHH
VRLRTAEQRLAWLADHLAEQPGSGIVYCLTVAATQEIADYLRSRGHEVAAYSGQTDPTER
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
HALEQDLVNGRVKALVATSALGMGFDATLGFVVNMGAPPSPVAYYQQVGRAGRGTTLPPE
HHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
GATVVLLPAIEDRDIWAYFASLAFPREEQVRRTLEVLGAEGRPLSTATLETYVDLNRTRL
CCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHH
ETMLKVLDVDGAVRRVRGGWEATGREWSYDEERYRRVTEARQREQQAMLDYIATDACRMR
HHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLRDQLDDPEAEDCGRCDNCGGLTLSADVSAAALEDAGARLARPGVAVEPRKMWPSALAN
HHHHHCCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHH
LGIELKGKIAEGAQEGRAVARLTDLGHGQALRELFAPATPDGPVPVPLVRAVLEVLGDWR
CCCEEECCHHHCHHHCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
PPVDAIVVVESQTRPTLTADLAAGLSRHLGVPVVGRWAIVNPDIVPGQGAANSAQRVAAV
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECEEEEECCCCCCCCCCCCHHHHHHHH
GRRFALQVDQPLDGLRVLLVDDRTDTGWTLTLAARAVRRAGAAEVRPLVLATTT
HHHEEEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]