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The map label for this gene is acdA [H]

Identifier: 119387185

GI number: 119387185

Start: 1694494

End: 1695639

Strand: Direct

Name: acdA [H]

Synonym: Pden_4480

Alternate gene names: 119387185

Gene position: 1694494-1695639 (Clockwise)

Preceding gene: 119387184

Following gene: 119387186

Centisome position: 97.94

GC content: 67.28

Gene sequence:

>1146_bases
ATGGATTTCGCGCTGAGCGAAGAGCAGCAGGCGATATTCGATCTGGCCCGGGATTTCGGGACGGCGGAAATCGCGCCCCA
AGCCCGCGCCTGGGAAGAGGCGGGCACCATTCCGCGCGAACTGTGGCAAAAGGCCGCCGAGCTGGGTTTCGGCGGCGTCT
ATGTCGGCGAGGAACACGGCGGCACCGGGCTTTCGCGCCTGGACGCGACGCTGGTCTTCGAGGCGCTGGCCATGGCCTGC
CCCTCGGTCGGCTCGTTCCTGTCGATCCACAACATGTGCGGCGGCATGATCGACAAGTTCGGCACCGACGCGAACAAGGC
GCGCTGGCTGCCCGGCCTGTGCAGCATGGAAAAGGTGTTCTCCTATTGCCTGACCGAGCCGGGCTCGGGCTCGGACGCCG
CCGCGCTGCGCACGCGGGCCGAGCGGGTCGAGGGCGGCTGGAAGCTGAACGGCACCAAGGCCTTCATCTCGGGCGGCAGC
TATTCGGATTGCTATCTGGTCATGGTCCGCACCGGGCAGGACGGGCCGCGCGGCATCTCGACCATGGTGGTCGAGGCCGG
CACGCCCGGCCTCAGCTTCGGCGCGCTCGAGCACAAGATGGGCTGGAAGGCGCAGCCGACCGCCCAGGTGCAGTTCGACG
ATTGCGTGATCCCCGAGGAAAACCTGATCGGCGAGGAAGGCCGGGGCTTCGCCTATGCCATGGCGGGCTTGGACGGCGGG
CGGCTGAACATCTCGGCCGGTGCGCTTGGCGGCGCGCAGGCGGCGCTGGACGCGACGCTGCGCTACATGGGCGAGCGTCG
CGCCTTTGGCCAGACGCTGGACCAGTTCCAGGCGCTGCAATTCCGCCTGGCCGAGATGGAGACGGCGCTGCAATCCTCGC
GCATCTTCCTGCGCCAGGCGGCATGGAAGCTGGACCGGGGCGACCGCGACGCCAGCAAGTTCTGCGCCATGGCCAAGCTG
CATGTGACCGACCGCGCCTTCGAGGTCGCCAATCAGTGCCTGCAATTGCATGGCGGTTACGGCTATCTTGCCGATTACGG
GATCGAAAAGATCGTGCGCGACCTGCGCGTGCACCAGATCCTGGAAGGCACCAATGAAATCATGCGGCTGATCGTCGGCC
GCGGCCTGCTGGCGGAGCGTGACTGA

Upstream 100 bases:

>100_bases
ACGCCCCCGCCCTTTTCCGCGCAAGCCTGCAAAACTTGCGCAACATTTCCCGGCCATGACCGGCAAGATACATCATCACG
AAAGACATGAGGGGGAGCAC

Downstream 100 bases:

>100_bases
ATGGCCGAGATGATCATCCGCAAGGACCGCCGCGCCGGGCGCCTGACCTTCAACCGCCCGCAGGCGCTGAACGCGCTGAG
CCACGAGATGGCGCTGGCCA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDFALSEEQQAIFDLARDFGTAEIAPQARAWEEAGTIPRELWQKAAELGFGGVYVGEEHGGTGLSRLDATLVFEALAMAC
PSVGSFLSIHNMCGGMIDKFGTDANKARWLPGLCSMEKVFSYCLTEPGSGSDAAALRTRAERVEGGWKLNGTKAFISGGS
YSDCYLVMVRTGQDGPRGISTMVVEAGTPGLSFGALEHKMGWKAQPTAQVQFDDCVIPEENLIGEEGRGFAYAMAGLDGG
RLNISAGALGGAQAALDATLRYMGERRAFGQTLDQFQALQFRLAEMETALQSSRIFLRQAAWKLDRGDRDASKFCAMAKL
HVTDRAFEVANQCLQLHGGYGYLADYGIEKIVRDLRVHQILEGTNEIMRLIVGRGLLAERD

Sequences:

>Translated_381_residues
MDFALSEEQQAIFDLARDFGTAEIAPQARAWEEAGTIPRELWQKAAELGFGGVYVGEEHGGTGLSRLDATLVFEALAMAC
PSVGSFLSIHNMCGGMIDKFGTDANKARWLPGLCSMEKVFSYCLTEPGSGSDAAALRTRAERVEGGWKLNGTKAFISGGS
YSDCYLVMVRTGQDGPRGISTMVVEAGTPGLSFGALEHKMGWKAQPTAQVQFDDCVIPEENLIGEEGRGFAYAMAGLDGG
RLNISAGALGGAQAALDATLRYMGERRAFGQTLDQFQALQFRLAEMETALQSSRIFLRQAAWKLDRGDRDASKFCAMAKL
HVTDRAFEVANQCLQLHGGYGYLADYGIEKIVRDLRVHQILEGTNEIMRLIVGRGLLAERD
>Mature_381_residues
MDFALSEEQQAIFDLARDFGTAEIAPQARAWEEAGTIPRELWQKAAELGFGGVYVGEEHGGTGLSRLDATLVFEALAMAC
PSVGSFLSIHNMCGGMIDKFGTDANKARWLPGLCSMEKVFSYCLTEPGSGSDAAALRTRAERVEGGWKLNGTKAFISGGS
YSDCYLVMVRTGQDGPRGISTMVVEAGTPGLSFGALEHKMGWKAQPTAQVQFDDCVIPEENLIGEEGRGFAYAMAGLDGG
RLNISAGALGGAQAALDATLRYMGERRAFGQTLDQFQALQFRLAEMETALQSSRIFLRQAAWKLDRGDRDASKFCAMAKL
HVTDRAFEVANQCLQLHGGYGYLADYGIEKIVRDLRVHQILEGTNEIMRLIVGRGLLAERD

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=52.2666666666667, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=35.1851851851852, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=35.1851851851852, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=38.563829787234, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=35.978835978836, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=35.7894736842105, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=34.1207349081365, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=34.7826086956522, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI76496475, Length=367, Percent_Identity=35.149863760218, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI4557235, Length=367, Percent_Identity=35.149863760218, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI21361497, Length=367, Percent_Identity=35.149863760218, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=26.8617021276596, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7669494, Length=355, Percent_Identity=26.1971830985915, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI48976061, Length=365, Percent_Identity=24.9315068493151, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=365, Percent_Identity=24.9315068493151, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38505218, Length=322, Percent_Identity=25.776397515528, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=31.266149870801, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1786223, Length=385, Percent_Identity=30.1298701298701, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI87082384, Length=287, Percent_Identity=27.1777003484321, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081702, Length=368, Percent_Identity=21.7391304347826, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=45.8885941644562, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=34.2931937172775, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=32.8083989501312, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=33.7662337662338, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=34.2465753424658, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=31.413612565445, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=32.3287671232877, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=34.5714285714286, Blast_Score=207, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17551932, Length=357, Percent_Identity=33.3333333333333, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=358, Percent_Identity=34.0782122905028, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=34.5195729537367, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=34, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=37.8260869565217, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=29.5620437956204, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=27.1276595744681, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562446, Length=364, Percent_Identity=24.1758241758242, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=27.8969957081545, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=333, Percent_Identity=26.1261261261261, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=333, Percent_Identity=26.1261261261261, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531913, Length=168, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=36.2433862433862, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=37.3015873015873, Blast_Score=248, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=36.8700265251989, Blast_Score=231, Evalue=5e-61,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=34.9869451697128, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=32.8767123287671, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI281363737, Length=346, Percent_Identity=32.6589595375723, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=27.154046997389, Blast_Score=131, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41321; Mature: 41321

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFALSEEQQAIFDLARDFGTAEIAPQARAWEEAGTIPRELWQKAAELGFGGVYVGEEHG
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCC
GTGLSRLDATLVFEALAMACPSVGSFLSIHNMCGGMIDKFGTDANKARWLPGLCSMEKVF
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
SYCLTEPGSGSDAAALRTRAERVEGGWKLNGTKAFISGGSYSDCYLVMVRTGQDGPRGIS
HHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCEEEEEEECCCCCCCCCE
TMVVEAGTPGLSFGALEHKMGWKAQPTAQVQFDDCVIPEENLIGEEGRGFAYAMAGLDGG
EEEEECCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCHHCCCCCCCCEEEEEECCCCC
RLNISAGALGGAQAALDATLRYMGERRAFGQTLDQFQALQFRLAEMETALQSSRIFLRQA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWKLDRGDRDASKFCAMAKLHVTDRAFEVANQCLQLHGGYGYLADYGIEKIVRDLRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LEGTNEIMRLIVGRGLLAERD
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDFALSEEQQAIFDLARDFGTAEIAPQARAWEEAGTIPRELWQKAAELGFGGVYVGEEHG
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCC
GTGLSRLDATLVFEALAMACPSVGSFLSIHNMCGGMIDKFGTDANKARWLPGLCSMEKVF
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
SYCLTEPGSGSDAAALRTRAERVEGGWKLNGTKAFISGGSYSDCYLVMVRTGQDGPRGIS
HHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCEEEEEEECCCCCCCCCE
TMVVEAGTPGLSFGALEHKMGWKAQPTAQVQFDDCVIPEENLIGEEGRGFAYAMAGLDGG
EEEEECCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCHHCCCCCCCCEEEEEECCCCC
RLNISAGALGGAQAALDATLRYMGERRAFGQTLDQFQALQFRLAEMETALQSSRIFLRQA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWKLDRGDRDASKFCAMAKLHVTDRAFEVANQCLQLHGGYGYLADYGIEKIVRDLRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LEGTNEIMRLIVGRGLLAERD
HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]