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The map label for this gene is fadB1 [H]

Identifier: 119386686

GI number: 119386686

Start: 1118017

End: 1118787

Strand: Direct

Name: fadB1 [H]

Synonym: Pden_3979

Alternate gene names: 119386686

Gene position: 1118017-1118787 (Clockwise)

Preceding gene: 119386685

Following gene: 119386690

Centisome position: 64.62

GC content: 69.52

Gene sequence:

>771_bases
ATGAGCTTTCAGACCATCGAAGTCACGCATCGGGACGGCATCGCAAGGCTGGCTCTGAACCGGCCCGACGTGGTCAACGC
GCTCAATCGCACCATGCGCGCCGAGATCGTCGCGGCACTGACGAACTTGCCGCAGGAGACGCGCTGCGTGGTGCTGACCG
GCAACGGGCGCGGCTTCTGTTCGGGCCAGGATCTGACCGATGCCGGCGGCGGGTTCGACGTCGAAACCATCCTGCGCGAG
GAATACGAGCCGATGCTGGCCGCCATCGCCGAGGCGCCGGTGCCTGTGATCGCCGCGGTGAACGGCATCGCGGCCGGGGC
GGGGGCCAATCTGGCGCTGGCCGCCGATGTGGTCATCGCTACGGAAAGCGCCAGCTTCGTGCAGGCTTTCAGCCGGATCG
GGCTGATCCCGGATGCGGGGGGGACGTTCATCGTGCCGCGTTCGGTCGGCGTGCCGCGTGCCATGGGGATGATGCTGTTC
GCCGACCGCATCCCCGCGACCCGGGCGGCGGAATGGGGGCTGATCTGGGAGGCGGTGCCGGACGCGGAGTTCGAGACCGT
CGTGGCCGCGCGGGCCAAGGCCCTGGCCGAGGGGCCGACGGCGGCTTTCCTGGCGATCCGGCAGGCTTTGCGCGCCTCGG
GCAACAACGACATGGCCGGGCAATTGCGGCTGGAGGCCCGGCTGCAAGGCGAGATGGCCCGGACCGAGGATTTCGCCGAA
GGTGTCGCGGCCTTCCTGGAAAAGCGCGCGCCCCGGTTCAAGGGACGCTGA

Upstream 100 bases:

>100_bases
GGCCAGGCTGGAAAGGATCTTGCGCGACTGACGCAGGGTCGGGGCTTTCCTGTCCCGCAGCACCCCGGCAGGATGGCCGA
AAGCAGGGGAAGAGGCAGGG

Downstream 100 bases:

>100_bases
TCCGGCGCGCCGTGATCGGCCGCGCCGCTCTGGCCTAGCCGATGCGCAGGAAGCGTGGGGTCGCCAGCCGGTTGTCGAAG
AAAGGCACGGATTGCGGCAG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSFQTIEVTHRDGIARLALNRPDVVNALNRTMRAEIVAALTNLPQETRCVVLTGNGRGFCSGQDLTDAGGGFDVETILRE
EYEPMLAAIAEAPVPVIAAVNGIAAGAGANLALAADVVIATESASFVQAFSRIGLIPDAGGTFIVPRSVGVPRAMGMMLF
ADRIPATRAAEWGLIWEAVPDAEFETVVAARAKALAEGPTAAFLAIRQALRASGNNDMAGQLRLEARLQGEMARTEDFAE
GVAAFLEKRAPRFKGR

Sequences:

>Translated_256_residues
MSFQTIEVTHRDGIARLALNRPDVVNALNRTMRAEIVAALTNLPQETRCVVLTGNGRGFCSGQDLTDAGGGFDVETILRE
EYEPMLAAIAEAPVPVIAAVNGIAAGAGANLALAADVVIATESASFVQAFSRIGLIPDAGGTFIVPRSVGVPRAMGMMLF
ADRIPATRAAEWGLIWEAVPDAEFETVVAARAKALAEGPTAAFLAIRQALRASGNNDMAGQLRLEARLQGEMARTEDFAE
GVAAFLEKRAPRFKGR
>Mature_255_residues
SFQTIEVTHRDGIARLALNRPDVVNALNRTMRAEIVAALTNLPQETRCVVLTGNGRGFCSGQDLTDAGGGFDVETILREE
YEPMLAAIAEAPVPVIAAVNGIAAGAGANLALAADVVIATESASFVQAFSRIGLIPDAGGTFIVPRSVGVPRAMGMMLFA
DRIPATRAAEWGLIWEAVPDAEFETVVAARAKALAEGPTAAFLAIRQALRASGNNDMAGQLRLEARLQGEMARTEDFAEG
VAAFLEKRAPRFKGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=219, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI260275230, Length=219, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI260274832, Length=219, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=28.1954887218045, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=30.5882352941176, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI37594471, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37594469, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150378541, Length=258, Percent_Identity=29.8449612403101, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI221136756, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221136753, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221307494, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI116235487, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=29.3103448275862, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI25453481, Length=207, Percent_Identity=25.6038647342995, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI51538573, Length=207, Percent_Identity=25.6038647342995, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4757966, Length=207, Percent_Identity=25.6038647342995, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI51538581, Length=207, Percent_Identity=25.6038647342995, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4757968, Length=208, Percent_Identity=25, Blast_Score=64, Evalue=1e-10,
Organism=Homo sapiens, GI49355787, Length=208, Percent_Identity=25, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=44.2231075697211, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=37.9446640316205, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=32.6771653543307, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI221142681, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=27.7153558052434, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790281, Length=224, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788682, Length=245, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=32.3770491803279, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17535521, Length=260, Percent_Identity=30, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=31.2252964426877, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17549921, Length=178, Percent_Identity=30.3370786516854, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=26.5384615384615, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540306, Length=266, Percent_Identity=30.4511278195489, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=28.740157480315, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=213, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=33.0708661417323, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20129971, Length=239, Percent_Identity=30.1255230125523, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24653477, Length=239, Percent_Identity=30.1255230125523, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24654903, Length=236, Percent_Identity=23.3050847457627, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19922422, Length=258, Percent_Identity=27.1317829457364, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28571729, Length=147, Percent_Identity=32.6530612244898, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571730, Length=147, Percent_Identity=32.6530612244898, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920382, Length=266, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357171, Length=218, Percent_Identity=27.0642201834862, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27034; Mature: 26903

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQTIEVTHRDGIARLALNRPDVVNALNRTMRAEIVAALTNLPQETRCVVLTGNGRGFC
CCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEE
SGQDLTDAGGGFDVETILREEYEPMLAAIAEAPVPVIAAVNGIAAGAGANLALAADVVIA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEEE
TESASFVQAFSRIGLIPDAGGTFIVPRSVGVPRAMGMMLFADRIPATRAAEWGLIWEAVP
ECCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECC
DAEFETVVAARAKALAEGPTAAFLAIRQALRASGNNDMAGQLRLEARLQGEMARTEDFAE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCHHHHHHHHHH
GVAAFLEKRAPRFKGR
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SFQTIEVTHRDGIARLALNRPDVVNALNRTMRAEIVAALTNLPQETRCVVLTGNGRGFC
CCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEE
SGQDLTDAGGGFDVETILREEYEPMLAAIAEAPVPVIAAVNGIAAGAGANLALAADVVIA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEEE
TESASFVQAFSRIGLIPDAGGTFIVPRSVGVPRAMGMMLFADRIPATRAAEWGLIWEAVP
ECCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECC
DAEFETVVAARAKALAEGPTAAFLAIRQALRASGNNDMAGQLRLEARLQGEMARTEDFAE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCHHHHHHHHHH
GVAAFLEKRAPRFKGR
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1743516 [H]