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The map label for this gene is adhc1 [H]

Identifier: 119385934

GI number: 119385934

Start: 376719

End: 377762

Strand: Direct

Name: adhc1 [H]

Synonym: Pden_3212

Alternate gene names: 119385934

Gene position: 376719-377762 (Clockwise)

Preceding gene: 119385933

Following gene: 119385935

Centisome position: 21.77

GC content: 61.88

Gene sequence:

>1044_bases
ATGACGCTGGTCAAAGCCCGCTGCACCTGCGCAGCCCATGCGCCCTTCGAGCCGATGATCATCGAGCGGCGCGAACTGGG
TCCGCATGATGTGATGATCGATATCGCCTTCGCTGGGATCTGTCATACCGATATCCATTACGCCTATGACGAGTTCGGTC
GCACGACCTATCCGCTGGTCCCCGGGCACGAGATCGCCGGTGTCGTCTCGGGGATCGGCAGCGATGTGAGCCGCTATCAG
GTGGGCGACAGGGTCGGAGTCGGCGTCATGGTCGATTCCTGCCGCAACTGCCCTGCCTGTAAGGCGGGGCAGGAACAATA
CTGCACCGGCAAGCGCATCATGACCTACAATTCGGTCGGCCGCGACGGTAAGCCGACCTATGGCGGTTACAGCCAGAAGA
TCGTCGTGGATGAAAACTATGTCGTCCGCATTCCGGAATCGATCCCGTTGGACCGTGCGGCACCGATGTTCTGCGCCGGC
GTGACTGTCTATTCGCCGTTGCGCCACTGGGGTGCCGGGCCAGGAAAGAGGGTGGCGATCCTGGGCTTCGGCGGGCTGGG
CCATCTGGGCGTTCAGATTGCCCATGCCATGGGAGCCGAGGTCATCGTGTTGGACATCGCGGAAAACAAGCGGGACGATG
CGATGCGCCTGGGCGCAAACGAGTTCCGCCTAGCCACCGATCCCCGGACCTTTCGCGACCTCGCGGGCAGGATCGACCTG
ATCATTTCGACCGTGCCGGTCGATATCGATCTTGACGAATATGCCGGGCTTCTCGCGCTGGACGGCACCTTCGTGAATAC
GGGCGTGCCTGCGAAGCCGCTTTCGATCGACGCAATCAACCTGCTGAACAACCGGCGCTCGGTTGCCGGCACGCGCAGCG
GCGGCATTGCCGAGACGCAGGAGATGATGGATTTCTGCGCCCTTCACGGCATCGGCGCCGAAGTCGAGATCATCAGCGCC
GACCAGATTGACGAGGCCTATGCGCGTGTACTGCGCGGGGACGTGAAGTTCCGTTTCGTCATCGACACCAACACGTTGCA
ATGA

Upstream 100 bases:

>100_bases
CATGGTGGTTTCAAGCATTCCGGCATCGGTCGCGAATGGGGCCGCTACGGGATCGAGGAATTTCTCGAATACCAGTCAAT
CATTGGCTGAGAGGGCAAGG

Downstream 100 bases:

>100_bases
GGTGAGTCACATGGCCCAAGCGAAGATTCTCACGGAACGCGAAGGCGCCGTCCTGCGGGTTACACTCAACGATCCGGCGA
CCCGCAACTCCCTGACGCCC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Ms-ADHC 1 [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTLVKARCTCAAHAPFEPMIIERRELGPHDVMIDIAFAGICHTDIHYAYDEFGRTTYPLVPGHEIAGVVSGIGSDVSRYQ
VGDRVGVGVMVDSCRNCPACKAGQEQYCTGKRIMTYNSVGRDGKPTYGGYSQKIVVDENYVVRIPESIPLDRAAPMFCAG
VTVYSPLRHWGAGPGKRVAILGFGGLGHLGVQIAHAMGAEVIVLDIAENKRDDAMRLGANEFRLATDPRTFRDLAGRIDL
IISTVPVDIDLDEYAGLLALDGTFVNTGVPAKPLSIDAINLLNNRRSVAGTRSGGIAETQEMMDFCALHGIGAEVEIISA
DQIDEAYARVLRGDVKFRFVIDTNTLQ

Sequences:

>Translated_347_residues
MTLVKARCTCAAHAPFEPMIIERRELGPHDVMIDIAFAGICHTDIHYAYDEFGRTTYPLVPGHEIAGVVSGIGSDVSRYQ
VGDRVGVGVMVDSCRNCPACKAGQEQYCTGKRIMTYNSVGRDGKPTYGGYSQKIVVDENYVVRIPESIPLDRAAPMFCAG
VTVYSPLRHWGAGPGKRVAILGFGGLGHLGVQIAHAMGAEVIVLDIAENKRDDAMRLGANEFRLATDPRTFRDLAGRIDL
IISTVPVDIDLDEYAGLLALDGTFVNTGVPAKPLSIDAINLLNNRRSVAGTRSGGIAETQEMMDFCALHGIGAEVEIISA
DQIDEAYARVLRGDVKFRFVIDTNTLQ
>Mature_346_residues
TLVKARCTCAAHAPFEPMIIERRELGPHDVMIDIAFAGICHTDIHYAYDEFGRTTYPLVPGHEIAGVVSGIGSDVSRYQV
GDRVGVGVMVDSCRNCPACKAGQEQYCTGKRIMTYNSVGRDGKPTYGGYSQKIVVDENYVVRIPESIPLDRAAPMFCAGV
TVYSPLRHWGAGPGKRVAILGFGGLGHLGVQIAHAMGAEVIVLDIAENKRDDAMRLGANEFRLATDPRTFRDLAGRIDLI
ISTVPVDIDLDEYAGLLALDGTFVNTGVPAKPLSIDAINLLNNRRSVAGTRSGGIAETQEMMDFCALHGIGAEVEIISAD
QIDEAYARVLRGDVKFRFVIDTNTLQ

Specific function: Prefers aldehydes over alcohols [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=299, Percent_Identity=30.1003344481605, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI4501933, Length=299, Percent_Identity=30.1003344481605, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4501929, Length=299, Percent_Identity=29.4314381270903, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI71565152, Length=325, Percent_Identity=28.3076923076923, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI71743840, Length=306, Percent_Identity=27.4509803921569, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI262073058, Length=306, Percent_Identity=27.4509803921569, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501939, Length=325, Percent_Identity=26.1538461538462, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI71565154, Length=245, Percent_Identity=26.9387755102041, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI156523966, Length=325, Percent_Identity=26.1538461538462, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI156627571, Length=222, Percent_Identity=25.2252252252252, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786518, Length=351, Percent_Identity=51.2820512820513, Blast_Score=317, Evalue=9e-88,
Organism=Escherichia coli, GI87082401, Length=346, Percent_Identity=32.9479768786127, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=27.3006134969325, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788075, Length=281, Percent_Identity=27.7580071174377, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790045, Length=199, Percent_Identity=32.1608040201005, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788407, Length=251, Percent_Identity=31.8725099601594, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788073, Length=203, Percent_Identity=28.0788177339901, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082125, Length=279, Percent_Identity=23.6559139784946, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI226510992, Length=207, Percent_Identity=30.9178743961353, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787863, Length=210, Percent_Identity=29.0476190476191, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786552, Length=229, Percent_Identity=29.6943231441048, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=316, Percent_Identity=29.1139240506329, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17562584, Length=340, Percent_Identity=29.4117647058824, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17562582, Length=325, Percent_Identity=30.4615384615385, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562876, Length=198, Percent_Identity=28.7878787878788, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562878, Length=198, Percent_Identity=29.7979797979798, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=232, Percent_Identity=28.0172413793103, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71997431, Length=234, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565904, Length=202, Percent_Identity=27.2277227722772, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323980, Length=326, Percent_Identity=36.8098159509202, Blast_Score=181, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319949, Length=326, Percent_Identity=33.7423312883436, Blast_Score=178, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=30.1538461538462, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324486, Length=341, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323729, Length=331, Percent_Identity=29.9093655589124, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319621, Length=328, Percent_Identity=28.6585365853659, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6319258, Length=231, Percent_Identity=29.004329004329, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320033, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=271, Percent_Identity=29.8892988929889, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=271, Percent_Identity=29.8892988929889, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319257, Length=290, Percent_Identity=25.5172413793103, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323099, Length=198, Percent_Identity=29.2929292929293, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17737897, Length=238, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17137530, Length=227, Percent_Identity=29.9559471365639, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737895, Length=246, Percent_Identity=26.8292682926829, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.2 [H]

Molecular weight: Translated: 37545; Mature: 37414

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVKARCTCAAHAPFEPMIIERRELGPHDVMIDIAFAGICHTDIHYAYDEFGRTTYPLV
CCEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEEEEEHHHHHHHHHHHCCEECCCC
PGHEIAGVVSGIGSDVSRYQVGDRVGVGVMVDSCRNCPACKAGQEQYCTGKRIMTYNSVG
CCHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCEEEEECCCC
RDGKPTYGGYSQKIVVDENYVVRIPESIPLDRAAPMFCAGVTVYSPLRHWGAGPGKRVAI
CCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
LGFGGLGHLGVQIAHAMGAEVIVLDIAENKRDDAMRLGANEFRLATDPRTFRDLAGRIDL
EEECCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCEEEECCCHHHHHHHCCEEE
IISTVPVDIDLDEYAGLLALDGTFVNTGVPAKPLSIDAINLLNNRRSVAGTRSGGIAETQ
EEEEEEEEEEHHHHCCEEEECCEEEECCCCCCCCEEHHHHHHCCCCCCCCCCCCCCHHHH
EMMDFCALHGIGAEVEIISADQIDEAYARVLRGDVKFRFVIDTNTLQ
HHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure 
TLVKARCTCAAHAPFEPMIIERRELGPHDVMIDIAFAGICHTDIHYAYDEFGRTTYPLV
CEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEEEEEHHHHHHHHHHHCCEECCCC
PGHEIAGVVSGIGSDVSRYQVGDRVGVGVMVDSCRNCPACKAGQEQYCTGKRIMTYNSVG
CCHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCEEEEECCCC
RDGKPTYGGYSQKIVVDENYVVRIPESIPLDRAAPMFCAGVTVYSPLRHWGAGPGKRVAI
CCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
LGFGGLGHLGVQIAHAMGAEVIVLDIAENKRDDAMRLGANEFRLATDPRTFRDLAGRIDL
EEECCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCEEEECCCHHHHHHHCCEEE
IISTVPVDIDLDEYAGLLALDGTFVNTGVPAKPLSIDAINLLNNRRSVAGTRSGGIAETQ
EEEEEEEEEEHHHHCCEEEECCEEEECCCCCCCCEEHHHHHHCCCCCCCCCCCCCCHHHH
EMMDFCALHGIGAEVEIISADQIDEAYARVLRGDVKFRFVIDTNTLQ
HHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11257547 [H]