Click here to switch to the map view.

The map label for this gene is adhB [H]

Identifier: 119385932

GI number: 119385932

Start: 374073

End: 375254

Strand: Direct

Name: adhB [H]

Synonym: Pden_3210

Alternate gene names: 119385932

Gene position: 374073-375254 (Clockwise)

Preceding gene: 119385926

Following gene: 119385933

Centisome position: 21.62

GC content: 65.14

Gene sequence:

>1182_bases
TTGAAAGTAAAAGGATCGTTCCTGCACGACGAGCCTGCGCTCAGGGTTTCGTTTGGTTGGGACGTACACGGGAATCTTAT
TAAAGACATGGATCGCGCGGGGCTTAGCCGTGCGGTCGTTGTTTGTGGACGCAGCTTGGCGAAGTCTGGCTCGGAACTGG
AACTGCTGCGTGAAGCGCTCGGCCCGCGTCTGGCTGGTATCCATCCCGGCGCACGCCCCCACAGCCCCGTTCCCCAGGTC
ATCGAGACCAGCCGTTTCCTGCGTGATGCCGGTGCCGATGCGGTCATCGCGGTCGGTGGCGGCTCAGCCATTGTGACCGC
CCGTGCCGCCAGCATCCTGCTGGCTGAGGGCGAGGATGTCGCGGCGCTTGCGACCTCGGTCACAGCCGAGGGTCGCATGA
TCAGCCCTCGACTGATGGCGCCCAAGCTGCCGCAATTCGTGATCCCGACGACGCCGACCACCGCAATCGTCAAGGCGGGC
AGCGCCATCTATGACGAGGTGGCGGACAAGCGGCGGGCGCTGTTCGATCCCAAGACGCGCAGCCAGGCCGTCTATGTCCA
CCCGGCGCTGCTGGCCCCCGTTCCGAAACAGGTCTTCGTCTCGGCTGGACTCAACACGCTTTGCATGGCGGTCGAAGGCC
TGATCGCCACAAAGGGCGATCCTCTTGCCGACGCACAACTGACGCACGCCTTGCGACTCGCCGCCGACGGGCTTGCCCAG
CTTAACGGGCCAGAGGCGGGGCAGGCGCGGGCCGATTTGATCTTTGCGGCTATTCTGTGCGGACGCGCCACGGACAGCAC
CAATGGCGGGCTGACGACGGCGCTGGGCCATGCCATCGGTGTCCGGCACCATGTCGAAAACGGTATCGTCAACGCCGTGG
TTCTGCCCAGCGTCATTGAATTCAACGCCGATGCAGCGGCCAGCGACCTGCACAAGGTCGAACGGGCGCTGGGCTTGGCG
AGGGCAGGCAGTGCGCGTGAAAGCGCCCTCGCGATCGGCCGGCATCTGGTGGCGCTGTTCGATGCTCTGGGGGTGCCGCG
CACGCTTGGCGAACTGGGCGTTCCGGCAGAGGCACGGCCTGAGCTGGCACAATTGGTGACCGAGGACTGGTTCCTGCGCG
GGAATCCCCGCCCGGTTCGCGACGCGACCGAGGTCGAACGAGTGATGACGACGCTTTGGTAA

Upstream 100 bases:

>100_bases
GGTCGCAATTACGATCAAATGTTCATAATGACGAACAAATGGCAAGTTGTCCAGACAATGTGCGTGGCGATGGCTGTGCT
GATCGAGGGAGGGGGAAATT

Downstream 100 bases:

>100_bases
CGCTGTCCAGGGCGCAACGCATGACGGCAGAGGAGGCCGAAGTGAAAAAGACCCATAATTTTGTGGGCGGGAAATGGATC
CCTGCCCAGGCAACTGGCGA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKVKGSFLHDEPALRVSFGWDVHGNLIKDMDRAGLSRAVVVCGRSLAKSGSELELLREALGPRLAGIHPGARPHSPVPQV
IETSRFLRDAGADAVIAVGGGSAIVTARAASILLAEGEDVAALATSVTAEGRMISPRLMAPKLPQFVIPTTPTTAIVKAG
SAIYDEVADKRRALFDPKTRSQAVYVHPALLAPVPKQVFVSAGLNTLCMAVEGLIATKGDPLADAQLTHALRLAADGLAQ
LNGPEAGQARADLIFAAILCGRATDSTNGGLTTALGHAIGVRHHVENGIVNAVVLPSVIEFNADAAASDLHKVERALGLA
RAGSARESALAIGRHLVALFDALGVPRTLGELGVPAEARPELAQLVTEDWFLRGNPRPVRDATEVERVMTTLW

Sequences:

>Translated_393_residues
MKVKGSFLHDEPALRVSFGWDVHGNLIKDMDRAGLSRAVVVCGRSLAKSGSELELLREALGPRLAGIHPGARPHSPVPQV
IETSRFLRDAGADAVIAVGGGSAIVTARAASILLAEGEDVAALATSVTAEGRMISPRLMAPKLPQFVIPTTPTTAIVKAG
SAIYDEVADKRRALFDPKTRSQAVYVHPALLAPVPKQVFVSAGLNTLCMAVEGLIATKGDPLADAQLTHALRLAADGLAQ
LNGPEAGQARADLIFAAILCGRATDSTNGGLTTALGHAIGVRHHVENGIVNAVVLPSVIEFNADAAASDLHKVERALGLA
RAGSARESALAIGRHLVALFDALGVPRTLGELGVPAEARPELAQLVTEDWFLRGNPRPVRDATEVERVMTTLW
>Mature_393_residues
MKVKGSFLHDEPALRVSFGWDVHGNLIKDMDRAGLSRAVVVCGRSLAKSGSELELLREALGPRLAGIHPGARPHSPVPQV
IETSRFLRDAGADAVIAVGGGSAIVTARAASILLAEGEDVAALATSVTAEGRMISPRLMAPKLPQFVIPTTPTTAIVKAG
SAIYDEVADKRRALFDPKTRSQAVYVHPALLAPVPKQVFVSAGLNTLCMAVEGLIATKGDPLADAQLTHALRLAADGLAQ
LNGPEAGQARADLIFAAILCGRATDSTNGGLTTALGHAIGVRHHVENGIVNAVVLPSVIEFNADAAASDLHKVERALGLA
RAGSARESALAIGRHLVALFDALGVPRTLGELGVPAEARPELAQLVTEDWFLRGNPRPVRDATEVERVMTTLW

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789163, Length=365, Percent_Identity=28.4931506849315, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082107, Length=293, Percent_Identity=28.3276450511945, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI48994951, Length=371, Percent_Identity=27.2237196765499, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321181, Length=312, Percent_Identity=26.9230769230769, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41142; Mature: 41142

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKGSFLHDEPALRVSFGWDVHGNLIKDMDRAGLSRAVVVCGRSLAKSGSELELLREAL
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHH
GPRLAGIHPGARPHSPVPQVIETSRFLRDAGADAVIAVGGGSAIVTARAASILLAEGEDV
CCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHEEEEECCCCH
AALATSVTAEGRMISPRLMAPKLPQFVIPTTPTTAIVKAGSAIYDEVADKRRALFDPKTR
HHHHHHHHCCCCEECCHHCCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCC
SQAVYVHPALLAPVPKQVFVSAGLNTLCMAVEGLIATKGDPLADAQLTHALRLAADGLAQ
CCEEEECHHHHCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LNGPEAGQARADLIFAAILCGRATDSTNGGLTTALGHAIGVRHHVENGIVNAVVLPSVIE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FNADAAASDLHKVERALGLARAGSARESALAIGRHLVALFDALGVPRTLGELGVPAEARP
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCH
ELAQLVTEDWFLRGNPRPVRDATEVERVMTTLW
HHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKVKGSFLHDEPALRVSFGWDVHGNLIKDMDRAGLSRAVVVCGRSLAKSGSELELLREAL
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHH
GPRLAGIHPGARPHSPVPQVIETSRFLRDAGADAVIAVGGGSAIVTARAASILLAEGEDV
CCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHEEEEECCCCH
AALATSVTAEGRMISPRLMAPKLPQFVIPTTPTTAIVKAGSAIYDEVADKRRALFDPKTR
HHHHHHHHCCCCEECCHHCCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCC
SQAVYVHPALLAPVPKQVFVSAGLNTLCMAVEGLIATKGDPLADAQLTHALRLAADGLAQ
CCEEEECHHHHCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LNGPEAGQARADLIFAAILCGRATDSTNGGLTTALGHAIGVRHHVENGIVNAVVLPSVIE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FNADAAASDLHKVERALGLARAGSARESALAIGRHLVALFDALGVPRTLGELGVPAEARP
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCH
ELAQLVTEDWFLRGNPRPVRDATEVERVMTTLW
HHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]