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The map label for this gene is insK [C]

Identifier: 119385884

GI number: 119385884

Start: 336263

End: 337168

Strand: Direct

Name: insK [C]

Synonym: Pden_3162

Alternate gene names: 119385884

Gene position: 336263-337168 (Clockwise)

Preceding gene: 119385883

Following gene: 119385885

Centisome position: 19.44

GC content: 63.02

Gene sequence:

>906_bases
ATGGTGGGTTTCATCGACGCGCATCGGGATGCGCACGGGGTCGAGCCGATCTGCGACGTTCTGCCGATCGCCCCTGCCAC
CTATTATGACCATCTGGCCAAACGTGCCGACCCGGCGCGGTTGTCGGATCGTGCCAAACGGGACGAGGCGCTGCGCCCCG
AGATACGGCGTGTTTTCGAGGACAACTGGAGCGTCTACGGCCTGCGCAAGGTCTGGCACCAGCTGCGCCGCGAGGGCTTC
GATATCGCTTGCTGCACGGTGGCACGGCTGATGAAGGACATGGGCATTCAAGGCATTGTCCGGGGCAAGCCGCACAAGAC
GACGATCCCTGACAAGAAGCAGCCATGCCCGCTGGACAAGGTGAACCGCCAGTTCCGCGTGCCTGCGCCGAACATGCTGT
GGGTCAGCGATTTCACCTATGTTGCCACCTGGAAGGGGTTTGTTTATGTCGCTTTCGTCATCGACGCTTATGCCCGCAAG
ATTGTCGGCTGGCGGGTCAGCACCTCGGCGTATGCCGGGTTCGTCCTTGATGCCCTCGAACAGGCGGTCCATGACCGCCG
CCCGGTCAAGGGCATGGGGCTGGTTCACCACAGCGACCGCGGCAGCCAGTATCTGTCGATCAAATACACTGAACGGCTGG
CCGAGGCGGGCATCGAGCCTTCGGTTGGCAGCGTCGGTGACAGCTACGACAACGCGCTGGCCGAGACGATCAACGGGCTC
TTCAAGGCCGAGGTCATCCACCGTCGGGGGCCCTGGCGCAGCTTCGAGGCCGTGGAATACGCAACCCTCGAATGGGTGGA
CTGGTTCAACAACCGCCGCCTGCTCGAGCCGATCGGGAACATCCCGCCCGCCGAAGCCGAGGCAAACTTCTACGCGGCTC
TGGAAACTGAAGCCATGGCCGCGTAA

Upstream 100 bases:

>100_bases
CCCTTGAACGGGAGAATCGCGAACTGCGCCAGGCGAACGAGATTCTCCGCAAGGCGTCGGCGTATTTTGCGATGGCGGAG
CTCGACCGCCGACCGAAGTG

Downstream 100 bases:

>100_bases
CTAAACCAAATCAGCCTCCGGCAAACCCGGCGCGGTTCATACCCCATCTGGCAGCCTGTCGTGAACGATCCCTGAATCCT
TTCGGTCTGGAGGCTTCCAT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MVGFIDAHRDAHGVEPICDVLPIAPATYYDHLAKRADPARLSDRAKRDEALRPEIRRVFEDNWSVYGLRKVWHQLRREGF
DIACCTVARLMKDMGIQGIVRGKPHKTTIPDKKQPCPLDKVNRQFRVPAPNMLWVSDFTYVATWKGFVYVAFVIDAYARK
IVGWRVSTSAYAGFVLDALEQAVHDRRPVKGMGLVHHSDRGSQYLSIKYTERLAEAGIEPSVGSVGDSYDNALAETINGL
FKAEVIHRRGPWRSFEAVEYATLEWVDWFNNRRLLEPIGNIPPAEAEANFYAALETEAMAA

Sequences:

>Translated_301_residues
MVGFIDAHRDAHGVEPICDVLPIAPATYYDHLAKRADPARLSDRAKRDEALRPEIRRVFEDNWSVYGLRKVWHQLRREGF
DIACCTVARLMKDMGIQGIVRGKPHKTTIPDKKQPCPLDKVNRQFRVPAPNMLWVSDFTYVATWKGFVYVAFVIDAYARK
IVGWRVSTSAYAGFVLDALEQAVHDRRPVKGMGLVHHSDRGSQYLSIKYTERLAEAGIEPSVGSVGDSYDNALAETINGL
FKAEVIHRRGPWRSFEAVEYATLEWVDWFNNRRLLEPIGNIPPAEAEANFYAALETEAMAA
>Mature_301_residues
MVGFIDAHRDAHGVEPICDVLPIAPATYYDHLAKRADPARLSDRAKRDEALRPEIRRVFEDNWSVYGLRKVWHQLRREGF
DIACCTVARLMKDMGIQGIVRGKPHKTTIPDKKQPCPLDKVNRQFRVPAPNMLWVSDFTYVATWKGFVYVAFVIDAYARK
IVGWRVSTSAYAGFVLDALEQAVHDRRPVKGMGLVHHSDRGSQYLSIKYTERLAEAGIEPSVGSVGDSYDNALAETINGL
FKAEVIHRRGPWRSFEAVEYATLEWVDWFNNRRLLEPIGNIPPAEAEANFYAALETEAMAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=248, Percent_Identity=54.0322580645161, Blast_Score=262, Evalue=2e-70,
Organism=Escherichia coli, GI1789981, Length=287, Percent_Identity=26.4808362369338, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788405, Length=244, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787263, Length=244, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786753, Length=244, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786570, Length=244, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786490, Length=244, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34103; Mature: 34103

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGFIDAHRDAHGVEPICDVLPIAPATYYDHLAKRADPARLSDRAKRDEALRPEIRRVFE
CCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DNWSVYGLRKVWHQLRREGFDIACCTVARLMKDMGIQGIVRGKPHKTTIPDKKQPCPLDK
CCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHH
VNRQFRVPAPNMLWVSDFTYVATWKGFVYVAFVIDAYARKIVGWRVSTSAYAGFVLDALE
HCCEEECCCCCEEEEECCHHEEHHHHHHHHHHHHHHHHHHHHCEEECHHHHHHHHHHHHH
QAVHDRRPVKGMGLVHHSDRGSQYLSIKYTERLAEAGIEPSVGSVGDSYDNALAETINGL
HHHHHCCCCCCCCEEEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
FKAEVIHRRGPWRSFEAVEYATLEWVDWFNNRRLLEPIGNIPPAEAEANFYAALETEAMA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEECHHHHC
A
C
>Mature Secondary Structure
MVGFIDAHRDAHGVEPICDVLPIAPATYYDHLAKRADPARLSDRAKRDEALRPEIRRVFE
CCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DNWSVYGLRKVWHQLRREGFDIACCTVARLMKDMGIQGIVRGKPHKTTIPDKKQPCPLDK
CCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHH
VNRQFRVPAPNMLWVSDFTYVATWKGFVYVAFVIDAYARKIVGWRVSTSAYAGFVLDALE
HCCEEECCCCCEEEEECCHHEEHHHHHHHHHHHHHHHHHHHHCEEECHHHHHHHHHHHHH
QAVHDRRPVKGMGLVHHSDRGSQYLSIKYTERLAEAGIEPSVGSVGDSYDNALAETINGL
HHHHHCCCCCCCCEEEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
FKAEVIHRRGPWRSFEAVEYATLEWVDWFNNRRLLEPIGNIPPAEAEANFYAALETEAMA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEECHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]