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The map label for this gene is cat2 [H]

Identifier: 119358479

GI number: 119358479

Start: 3104167

End: 3105456

Strand: Reverse

Name: cat2 [H]

Synonym: Cpha266_2715

Alternate gene names: 119358479

Gene position: 3105456-3104167 (Counterclockwise)

Preceding gene: 119358480

Following gene: 119358477

Centisome position: 99.09

GC content: 52.95

Gene sequence:

>1290_bases
ATGCATTACCGGACGATTTCAGCAGATGAGGCAGTTTCTGTCATTAAGTCAGGCAACAGGGTTTTTCTCCATACAGCGGC
AGCAACCCCTCATAGGCTCATTGACGCGATGGTGAGGAGGGCTGACGAATTACGAAACGTTGAGATAGTCAGTCTTCATA
CAGAAGGGGCCGCCGACTATGTGCTCCCCGAATACCAGAAAAGTTTCAGGCTTAACGCCTTTTTTGTCGGGCGTAATGTT
CGCAAATCGGTACAGGACGGGTTATCTGACGCCATACCGATTTTTCTCAGCGATGTTCCCTCAATGTTCTACAACGGGAT
TCTCCCCCTTGACGTTGCCCTTGTTCATGTTTCGCCGCCGGATCGCCACGGATACTGTTCGCTTGGCGTGTCGGTAGATG
CAGCGCTTGCCGCAGTCCAGACGGCTCGTTACGTAATTGCGCAGGTAAATCCGCATATGCCTCGAACTCACGGACAAGGA
ATGCTGCATGTCAGCAAGATTCACGCGCTTGTTGACGTGGACGATCAGCTTCCCGAAACGCCAAGGCACGAGCTCAGCGA
GGTGGAGCTGCAGATAGGAAAACATATCGCATCCATTGTTGAGGACGGAGCTACGCTGCAAATGGGTATCGGGGCCATTC
CGGATGCGACGCTGGCCGCGCTTGGCGGGCATAAGGATCTTGGCGTCCACTCCGAAATGTTTTCGGATGGCGTGGTGGAT
CTTGTCGAAAAAGGGGTAATTACAGGCAGGCACAAGAAAATTTACAACCAGATCATTGTCGCGAGCTTTATGGTCGGGAC
GAAACGCCTCTACGATTTTGTCAACGACAACCCGCTGGTCGAAATGCTTGGTTCCGATGTCGTAAACGATACCAGTGAGA
TCAGAAAAAACCCGAGGGTGACGGCTATCAACAGCGCGCTTGAAATCGATATGAGTGGCCAGGTCTGTGCGGACTCGATC
GGGCAGAAATACTTTTCCGGCGTCGGCGGCCAGATGGATTTTATTCGCGGCGCGGCGCTATCCGAAGGAGGCAAGCCAAT
CATAGCCCTGCCTGCTACCACAAAAAAAGGCGAATCGAGAATTGTAGCCCAGCTCAAGCACGGCGCGGGAGTCGTTACTA
CCAGAGCGCATGTGCAGTACGTTGTGACCGAGTACGGAATCGTGAACCTGCACGGCAAAAACCTCCGTCAGAGGGCTTTG
AGTCTTGCAGGAATTGCTCATCCCGATTTCCGCGAAGATATCTGCCGTCAGGCATATAACCTCTACGGGCCGAAAAGTCA
GGGCGAATAA

Upstream 100 bases:

>100_bases
AGGAAGATCAGATTCACAAAGGACAGTCCGAACTTCCTGCCTATCTTCGAAGAAAAAATAACGGGACATGACAAGTCCCG
TTTACTAATCAAAGTGTTTT

Downstream 100 bases:

>100_bases
TCGTCACTTGCGAGCGGAACGGAAGATTCGCCCCCATCGTCGGAATCAGACGATGCAAAAAAACTTTAGAGAGCGTGCGG
CAGGAGAAATGACCGGAAGG

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MHYRTISADEAVSVIKSGNRVFLHTAAATPHRLIDAMVRRADELRNVEIVSLHTEGAADYVLPEYQKSFRLNAFFVGRNV
RKSVQDGLSDAIPIFLSDVPSMFYNGILPLDVALVHVSPPDRHGYCSLGVSVDAALAAVQTARYVIAQVNPHMPRTHGQG
MLHVSKIHALVDVDDQLPETPRHELSEVELQIGKHIASIVEDGATLQMGIGAIPDATLAALGGHKDLGVHSEMFSDGVVD
LVEKGVITGRHKKIYNQIIVASFMVGTKRLYDFVNDNPLVEMLGSDVVNDTSEIRKNPRVTAINSALEIDMSGQVCADSI
GQKYFSGVGGQMDFIRGAALSEGGKPIIALPATTKKGESRIVAQLKHGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAL
SLAGIAHPDFREDICRQAYNLYGPKSQGE

Sequences:

>Translated_429_residues
MHYRTISADEAVSVIKSGNRVFLHTAAATPHRLIDAMVRRADELRNVEIVSLHTEGAADYVLPEYQKSFRLNAFFVGRNV
RKSVQDGLSDAIPIFLSDVPSMFYNGILPLDVALVHVSPPDRHGYCSLGVSVDAALAAVQTARYVIAQVNPHMPRTHGQG
MLHVSKIHALVDVDDQLPETPRHELSEVELQIGKHIASIVEDGATLQMGIGAIPDATLAALGGHKDLGVHSEMFSDGVVD
LVEKGVITGRHKKIYNQIIVASFMVGTKRLYDFVNDNPLVEMLGSDVVNDTSEIRKNPRVTAINSALEIDMSGQVCADSI
GQKYFSGVGGQMDFIRGAALSEGGKPIIALPATTKKGESRIVAQLKHGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAL
SLAGIAHPDFREDICRQAYNLYGPKSQGE
>Mature_429_residues
MHYRTISADEAVSVIKSGNRVFLHTAAATPHRLIDAMVRRADELRNVEIVSLHTEGAADYVLPEYQKSFRLNAFFVGRNV
RKSVQDGLSDAIPIFLSDVPSMFYNGILPLDVALVHVSPPDRHGYCSLGVSVDAALAAVQTARYVIAQVNPHMPRTHGQG
MLHVSKIHALVDVDDQLPETPRHELSEVELQIGKHIASIVEDGATLQMGIGAIPDATLAALGGHKDLGVHSEMFSDGVVD
LVEKGVITGRHKKIYNQIIVASFMVGTKRLYDFVNDNPLVEMLGSDVVNDTSEIRKNPRVTAINSALEIDMSGQVCADSI
GQKYFSGVGGQMDFIRGAALSEGGKPIIALPATTKKGESRIVAQLKHGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAL
SLAGIAHPDFREDICRQAYNLYGPKSQGE

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=484, Percent_Identity=25, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=424, Percent_Identity=50.2358490566038, Blast_Score=415, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17538151, Length=428, Percent_Identity=45.3271028037383, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319456, Length=395, Percent_Identity=24.0506329113924, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358615, Length=419, Percent_Identity=54.653937947494, Blast_Score=473, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46563; Mature: 46563

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYRTISADEAVSVIKSGNRVFLHTAAATPHRLIDAMVRRADELRNVEIVSLHTEGAADY
CCCEECCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
VLPEYQKSFRLNAFFVGRNVRKSVQDGLSDAIPIFLSDVPSMFYNGILPLDVALVHVSPP
CCHHHHHHCEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
DRHGYCSLGVSVDAALAAVQTARYVIAQVNPHMPRTHGQGMLHVSKIHALVDVDDQLPET
CCCCEEEECCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEHHHHHHEEECCCCCCCC
PRHELSEVELQIGKHIASIVEDGATLQMGIGAIPDATLAALGGHKDLGVHSEMFSDGVVD
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHCHHHH
LVEKGVITGRHKKIYNQIIVASFMVGTKRLYDFVNDNPLVEMLGSDVVNDTSEIRKNPRV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCHHHHHCCCCE
TAINSALEIDMSGQVCADSIGQKYFSGVGGQMDFIRGAALSEGGKPIIALPATTKKGESR
EEECCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCHHHCCCCCEEEEECCCCCCCCHH
IVAQLKHGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRALSLAGIAHPDFREDICRQAYN
HHHHHHCCCCEEEEHHHHEEEEECCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LYGPKSQGE
CCCCCCCCC
>Mature Secondary Structure
MHYRTISADEAVSVIKSGNRVFLHTAAATPHRLIDAMVRRADELRNVEIVSLHTEGAADY
CCCEECCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
VLPEYQKSFRLNAFFVGRNVRKSVQDGLSDAIPIFLSDVPSMFYNGILPLDVALVHVSPP
CCHHHHHHCEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
DRHGYCSLGVSVDAALAAVQTARYVIAQVNPHMPRTHGQGMLHVSKIHALVDVDDQLPET
CCCCEEEECCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEHHHHHHEEECCCCCCCC
PRHELSEVELQIGKHIASIVEDGATLQMGIGAIPDATLAALGGHKDLGVHSEMFSDGVVD
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHCHHHH
LVEKGVITGRHKKIYNQIIVASFMVGTKRLYDFVNDNPLVEMLGSDVVNDTSEIRKNPRV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCHHHHHCCCCE
TAINSALEIDMSGQVCADSIGQKYFSGVGGQMDFIRGAALSEGGKPIIALPATTKKGESR
EEECCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCHHHCCCCCEEEEECCCCCCCCHH
IVAQLKHGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRALSLAGIAHPDFREDICRQAYN
HHHHHHCCCCEEEEHHHHEEEEECCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LYGPKSQGE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]