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The map label for this gene is nreC [H]

Identifier: 119358450

GI number: 119358450

Start: 3080349

End: 3080960

Strand: Reverse

Name: nreC [H]

Synonym: Cpha266_2686

Alternate gene names: 119358450

Gene position: 3080960-3080349 (Counterclockwise)

Preceding gene: 119358451

Following gene: 119358449

Centisome position: 98.31

GC content: 52.45

Gene sequence:

>612_bases
ATGATTACCATTATCATAGCCGACGACCACAAAATATTCCGACAGGGATTATCGAGGCTTCTTGCCGATGACGACAGGTT
CAAGCTTCTTGGCGAGGCAAGTAACGGCAAAGAGGCGCTTAATCTTATCTGGAAAGAGAAGCCGCAGGTAGCGGTGCTGG
ATCTTTCCATGCCGAGACCCGATGGCCTTGAAGTCGTATCAAGTATTCGGGCAGCCCACAGCAACACCCGATGCATTATT
CTCACCATGAAGGACGACATCGAAACCGTTCGGCGCGCTCTTGAAAGCGGGGTATACGGCTACGTGCTCAAAGAGGCTGC
ATACGAAGAGATCGCCGAGGCAATCGTCAAAGTTGCCGACAACAAACTCTATCTCGGCAGATTTCAGGACAATCCGAACC
TCTATGCGAGTTGCTGCGAAGGGCAGTTAACGAACAGGGAGGTCGAAGTGCTCCGCTGCGTTGTGCGAGGTCTTACCAGT
CGGCAGATAGCCAGCGAACTGTTTATCAGCCACCGCACGGTTGAAACGCACAGGCAGCACATCATGGAAAAACTGAACAT
CCGTACCGCAACAGGACTGGCAGGGTACGCCCGCGAACACGGTTTGATATAA

Upstream 100 bases:

>100_bases
GACTGCGAATCATAGAGGAACGGGTTTCGCTCATAGGCGGAAAGCTCGACATGGCATCCACCGCTTCGGGCACCACAATT
ACCGTGACGCTGGAGTTGCC

Downstream 100 bases:

>100_bases
ACCATCCCCGTCACCCCCGCTCCTCGACGTCATACCGTTTCCCCAACGATAAAAAAATCCCTGCAACCAGCTCTCATCCC
CGATGGCATCCAATGCTGAC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MITIIIADDHKIFRQGLSRLLADDDRFKLLGEASNGKEALNLIWKEKPQVAVLDLSMPRPDGLEVVSSIRAAHSNTRCII
LTMKDDIETVRRALESGVYGYVLKEAAYEEIAEAIVKVADNKLYLGRFQDNPNLYASCCEGQLTNREVEVLRCVVRGLTS
RQIASELFISHRTVETHRQHIMEKLNIRTATGLAGYAREHGLI

Sequences:

>Translated_203_residues
MITIIIADDHKIFRQGLSRLLADDDRFKLLGEASNGKEALNLIWKEKPQVAVLDLSMPRPDGLEVVSSIRAAHSNTRCII
LTMKDDIETVRRALESGVYGYVLKEAAYEEIAEAIVKVADNKLYLGRFQDNPNLYASCCEGQLTNREVEVLRCVVRGLTS
RQIASELFISHRTVETHRQHIMEKLNIRTATGLAGYAREHGLI
>Mature_203_residues
MITIIIADDHKIFRQGLSRLLADDDRFKLLGEASNGKEALNLIWKEKPQVAVLDLSMPRPDGLEVVSSIRAAHSNTRCII
LTMKDDIETVRRALESGVYGYVLKEAAYEEIAEAIVKVADNKLYLGRFQDNPNLYASCCEGQLTNREVEVLRCVVRGLTS
RQIASELFISHRTVETHRQHIMEKLNIRTATGLAGYAREHGLI

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=32.48730964467, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=29.5238095238095, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=32.8205128205128, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=25.2427184466019, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788712, Length=200, Percent_Identity=26.5, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788546, Length=202, Percent_Identity=25.7425742574257, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=33.6538461538462, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22848; Mature: 22848

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIIIADDHKIFRQGLSRLLADDDRFKLLGEASNGKEALNLIWKEKPQVAVLDLSMPRP
CEEEEEECCHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCC
DGLEVVSSIRAAHSNTRCIILTMKDDIETVRRALESGVYGYVLKEAAYEEIAEAIVKVAD
CHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
NKLYLGRFQDNPNLYASCCEGQLTNREVEVLRCVVRGLTSRQIASELFISHRTVETHRQH
CEEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IMEKLNIRTATGLAGYAREHGLI
HHHHHCCCHHCCHHHHHHHCCCC
>Mature Secondary Structure
MITIIIADDHKIFRQGLSRLLADDDRFKLLGEASNGKEALNLIWKEKPQVAVLDLSMPRP
CEEEEEECCHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCC
DGLEVVSSIRAAHSNTRCIILTMKDDIETVRRALESGVYGYVLKEAAYEEIAEAIVKVAD
CHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
NKLYLGRFQDNPNLYASCCEGQLTNREVEVLRCVVRGLTSRQIASELFISHRTVETHRQH
CEEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IMEKLNIRTATGLAGYAREHGLI
HHHHHCCCHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]