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The map label for this gene is gpsA

Identifier: 119358348

GI number: 119358348

Start: 2954894

End: 2955895

Strand: Reverse

Name: gpsA

Synonym: Cpha266_2580

Alternate gene names: 119358348

Gene position: 2955895-2954894 (Counterclockwise)

Preceding gene: 119358349

Following gene: 119358344

Centisome position: 94.32

GC content: 54.39

Gene sequence:

>1002_bases
ATGAAAATCGCTGTATCAGGCGCGGGAAGCTGGGGCACGACTCTTGCTGTTCTGCTTGCCAATAAGGGCCATGAGGTGCT
GTTGTGGGCTCATCGTCCGGAATTTGCTGCCGCGCTCGAATCTGACAGGGAGAATATCCGCTATCTCAAGGGTGTTCGTT
TTCCTGAAAATCTTCATGTCGTCTCTTCTCTTCGTGACGCGGTTATCTCTTCGGAGATGGTCGTGACGGCCGTGCCTTCG
CAGGCGCTGCGCGAAACGGTTGCGATGTTCAGCGATTGTTCCCTTGACGGGAAAATTATTGTGAATGTTTCAAAGGGTAT
TGAGCTGAAGAGCGGAAAACGGATGTCGGAGGTGCTTCTTGAAGTGCTTCCGACTCTTCATGCTTCGCAGGTTGCGACGC
TTTCGGGGCCGAGTCATGCCGAAGAGGTTTCTAAAGGTCAGCCGACGACCGTTGTCGCTTCGTCGGTTTCGATGGGGACG
GCTGAAATCGTTCAGGAGGCGTTTCATACGGGGATGTTCCGGGTCTATGTCAATACGGATATTATCGGGGTTGAGCTGGC
TGGCGCCGTAAAGAATATTATCGCTATTGCTGCCGGGATTACCGAAGGTGTCGGGTTTGGGGATAATGCCAAGGCGGCTA
TTATTACCCGGGGCCTTGCCGAGATGTCGAGGCTCTGTATCCGGCTGGGGGCCGACCCTCATACGGTGTCGGGTCTTTCG
GGTATCGGCGATCTCGTGGTGACCTGTCTGAGTCGGCATAGCCGAAATCGTTATGTGGGCGAGCAGATCGGCGCCGGTCG
TTCGCTGGATGATATTGTCAGCCAGATGAATATGGTTGCCGAAGGGGTGCTTACTTCCAAGGCGGTGTTCGAGCTGAGCC
GGTCGGTCGGCGTTGAGATGCCTATTACCCAGGCGGTGTACGAGATGCTTTTTGAGCATAAGCCGGTTCAGGAGGCGATT
CTTGACCTGATGAACCGGGAGCCGAAAAAAGAGCACTATTAA

Upstream 100 bases:

>100_bases
TGCTATTCTGTATACTCATCGTGCTAATATCAGAAGACTGCTTTCCGGGACGGAAAACCGTATCAAGTTTGGCAGGCACT
CCTGATCTCCTGAATCTTTG

Downstream 100 bases:

>100_bases
GGGGCTCTTTCGATATCTGTTCCGCTTTTTCCCGCCGCCCCGCTTTCTGTCTGTCCGGTCTACGTTTTCTGCTTTTTGGG
GGTTTCGTACCAGACTCTTT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKIAVSGAGSWGTTLAVLLANKGHEVLLWAHRPEFAAALESDRENIRYLKGVRFPENLHVVSSLRDAVISSEMVVTAVPS
QALRETVAMFSDCSLDGKIIVNVSKGIELKSGKRMSEVLLEVLPTLHASQVATLSGPSHAEEVSKGQPTTVVASSVSMGT
AEIVQEAFHTGMFRVYVNTDIIGVELAGAVKNIIAIAAGITEGVGFGDNAKAAIITRGLAEMSRLCIRLGADPHTVSGLS
GIGDLVVTCLSRHSRNRYVGEQIGAGRSLDDIVSQMNMVAEGVLTSKAVFELSRSVGVEMPITQAVYEMLFEHKPVQEAI
LDLMNREPKKEHY

Sequences:

>Translated_333_residues
MKIAVSGAGSWGTTLAVLLANKGHEVLLWAHRPEFAAALESDRENIRYLKGVRFPENLHVVSSLRDAVISSEMVVTAVPS
QALRETVAMFSDCSLDGKIIVNVSKGIELKSGKRMSEVLLEVLPTLHASQVATLSGPSHAEEVSKGQPTTVVASSVSMGT
AEIVQEAFHTGMFRVYVNTDIIGVELAGAVKNIIAIAAGITEGVGFGDNAKAAIITRGLAEMSRLCIRLGADPHTVSGLS
GIGDLVVTCLSRHSRNRYVGEQIGAGRSLDDIVSQMNMVAEGVLTSKAVFELSRSVGVEMPITQAVYEMLFEHKPVQEAI
LDLMNREPKKEHY
>Mature_333_residues
MKIAVSGAGSWGTTLAVLLANKGHEVLLWAHRPEFAAALESDRENIRYLKGVRFPENLHVVSSLRDAVISSEMVVTAVPS
QALRETVAMFSDCSLDGKIIVNVSKGIELKSGKRMSEVLLEVLPTLHASQVATLSGPSHAEEVSKGQPTTVVASSVSMGT
AEIVQEAFHTGMFRVYVNTDIIGVELAGAVKNIIAIAAGITEGVGFGDNAKAAIITRGLAEMSRLCIRLGADPHTVSGLS
GIGDLVVTCLSRHSRNRYVGEQIGAGRSLDDIVSQMNMVAEGVLTSKAVFELSRSVGVEMPITQAVYEMLFEHKPVQEAI
LDLMNREPKKEHY

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=352, Percent_Identity=27.5568181818182, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI33695088, Length=353, Percent_Identity=26.9121813031161, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790037, Length=333, Percent_Identity=43.8438438438438, Blast_Score=272, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=28.7323943661972, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI32564399, Length=358, Percent_Identity=28.4916201117318, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193210136, Length=365, Percent_Identity=27.1232876712329, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=365, Percent_Identity=27.1232876712329, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=350, Percent_Identity=25.4285714285714, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320181, Length=348, Percent_Identity=26.4367816091954, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324513, Length=341, Percent_Identity=26.6862170087977, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136202, Length=350, Percent_Identity=25.1428571428571, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17136204, Length=350, Percent_Identity=25.1428571428571, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17136200, Length=350, Percent_Identity=25.1428571428571, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI22026922, Length=354, Percent_Identity=23.4463276836158, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45551945, Length=236, Percent_Identity=24.5762711864407, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281362270, Length=236, Percent_Identity=24.5762711864407, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648969, Length=187, Percent_Identity=25.668449197861, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_CHLPD (A1BJJ1)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912992.1
- ProteinModelPortal:   A1BJJ1
- SMR:   A1BJJ1
- STRING:   A1BJJ1
- GeneID:   4569095
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2580
- NMPDR:   fig|290317.7.peg.2699
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35662; Mature: 35662

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 105-105 BINDING 105-105 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVSGAGSWGTTLAVLLANKGHEVLLWAHRPEFAAALESDRENIRYLKGVRFPENLHV
CEEEEECCCCHHHHHHHHEECCCCEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCHHHH
VSSLRDAVISSEMVVTAVPSQALRETVAMFSDCSLDGKIIVNVSKGIELKSGKRMSEVLL
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHH
EVLPTLHASQVATLSGPSHAEEVSKGQPTTVVASSVSMGTAEIVQEAFHTGMFRVYVNTD
HHHHCHHHHHEEECCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEECC
IIGVELAGAVKNIIAIAAGITEGVGFGDNAKAAIITRGLAEMSRLCIRLGADPHTVSGLS
EEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCHH
GIGDLVVTCLSRHSRNRYVGEQIGAGRSLDDIVSQMNMVAEGVLTSKAVFELSRSVGVEM
HHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PITQAVYEMLFEHKPVQEAILDLMNREPKKEHY
CHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKIAVSGAGSWGTTLAVLLANKGHEVLLWAHRPEFAAALESDRENIRYLKGVRFPENLHV
CEEEEECCCCHHHHHHHHEECCCCEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCHHHH
VSSLRDAVISSEMVVTAVPSQALRETVAMFSDCSLDGKIIVNVSKGIELKSGKRMSEVLL
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHH
EVLPTLHASQVATLSGPSHAEEVSKGQPTTVVASSVSMGTAEIVQEAFHTGMFRVYVNTD
HHHHCHHHHHEEECCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEECC
IIGVELAGAVKNIIAIAAGITEGVGFGDNAKAAIITRGLAEMSRLCIRLGADPHTVSGLS
EEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCHH
GIGDLVVTCLSRHSRNRYVGEQIGAGRSLDDIVSQMNMVAEGVLTSKAVFELSRSVGVEM
HHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PITQAVYEMLFEHKPVQEAILDLMNREPKKEHY
CHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA