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The map label for this gene is psrA [H]

Identifier: 119358330

GI number: 119358330

Start: 2936146

End: 2938308

Strand: Direct

Name: psrA [H]

Synonym: Cpha266_2562

Alternate gene names: 119358330

Gene position: 2936146-2938308 (Clockwise)

Preceding gene: 119358329

Following gene: 119358331

Centisome position: 93.69

GC content: 54.74

Gene sequence:

>2163_bases
TTGCAGGATCAAGCGCACTCTCAGCCCGGTGCCGTACAGGCTTTTTCAGGCCGCAACTCCGCCGTATCAGGCGAGTCCGG
AGAAAAAGTCGTTTACTCGATCTGCGAGCACTGTTTCTGGCGGTGCGGAATTGCCGCTCATGTACGCGACGGAAAGGTAT
ACAAGATCACCGGATCGGAACATCACCCGCTCAGCCAGGGAAAACTCTGCCCGAGAGGCACCGGAGGAATCGGCCAGTTG
TACGACCCCGACCGTCTTGCTCACCCCCTGATCCGTGAAACAAGAGGCGGAAAACAGTACTACAGAAAAGCCACCTGGGA
CGAAGCTGTCGGAGTTGTTGCGGAAAAGCTCTACAAAACAAGCCAGACCTACGGCCCAGGCTCGATAGCCATGCTGCACC
ACGGCTACGGAGTCTCGTTCTTCAAAAAAATGCTCTCGGAAATCGGGGTCAACAAAATCGCCAAACCATCCTACGATCTC
TGCTGCGGCCCTGCCCGTCAGGCAGCCGTGCTTACCTATGGCTACCCCAGCGACACCCCCGAAGGATTCGATATGATGAA
CAGTAAATACATGATCTTTTTCGGAACCCATTTCGGAGAGAACATGCACAACACCGCCGTTCAGGAGATTTCCGAAGGGA
TCCGCCGCGGAGCAAAAATCGTCGTTTTCGACCCCCGCTTCTCGACGCTTGCGGGAAAAGCCGATCACTGGCTCCCCATC
AAACCGGCAACGGATATCGCCATGATGCAGGGCCTCATGCACGTGCTCATCAGCGAAGAAATTTACGACAAAGCGTTTGT
CGAAGCCCACACCGTCGGTTTTGGCGAGCTTTGGGAATCCGTACGAGAGATGACCCCGGAAAAAGTTTCGGCAATCACCG
ACATCCCGGCCGATGCCATCCGCACCGTGGCAAGAGAGTACGCATTCCATGCTCCGGCAGCCTTCGTACACAGCGGACGA
CGGACCAACTGGTACGGCGACGCCCTGCAAAGACTCCGCGCCATCCATATACTCAACGCCCTGGTTGGTAACTTCAAAAT
GCCCGGCGGCGTCGTCGCCTTCGAAAAGTTTCCGCTTGTTCAACCTCCGGCAGCGCACGAACACCCTGCCTACGAAAAAG
AGGTCTACAGCAAATACCCGTTCTTTCCGAACGACGAACCCTCAAACACCATCGCCTCGCACGAAATCGTACAACAGGCC
ATATCCGGAGAGGTCAAGGCGCTGGTTATCTACGGAGTCAACCTCCCGGAAACCATGACCCTTGGAAGAAAAGCCGCCAT
AGAGGCCCTTGAAAAAGTTGACTTCATGGTTGCCATTGATGTGCTGCCTGCAGAGGTTACCGGCTACGCCGACGTGGTGC
TACCGGAATGCACCTATCTTGAACGGTACGACGATCTCGATAACGGACGAGCCTTCCGCACCCCTTTTGTAGCACTCCGC
CAACCGGCTGTTCCCCCCATGTACGAATCAAAACCCGGCAACCAGATCGCAAAAATGATTACCGACAAATGGGGACTCCA
CGGCGTCTTTGCGCCAACGGTCGAAGCCGGTCTCAATAAAAAACTCGGACTCATCGGCAGCTCCCTTGAAGAGATAAAGA
AAAAAGGAGTGCTCGTCATGCCGGCAACCGACCTGTACCGAAAACCCGGCGAAGCGCTCAACCTGAAAACGCCGAGCGGA
AAAATCGAACTCGCTTCGGAACAGCTCAAAACAGGAGGATTCGACGCCGTTCCGACCTATACGGCCCATCCCGAACCACC
GGCAGGCTTCTACCGGATGCTGACGGGCCGCAAACCGATGCTCACCTTCGGGCGAACGGCCAACAACCGCTTCCTCGGAG
ATCTTGCCACAGCAAAAGAAAACGAAGTCTGGGTCAACGAACAAATCGCCGGCAAACACAACATTACCAATGGAGAGTAT
GTTCACCTGAAAAACCAGGACGGCGTCATCTCTCAATTTCCGGTAAAAGTCAAGGTAACGCAGCGAATACGACCCGATGC
CGTCTACATGGTTCACGGATTCGGACACACCTCTGCAAAGCTCACCTGGGCCTACAAACGGGGAGCATCGCATAACCAGC
TTATAACAAGAACCGAAATAGACCCGGCAATGGGTGCCGTTGGCTTTCAGAACAACTTTGTGACATTCATCAAGGAGGCA
TAA

Upstream 100 bases:

>100_bases
AGCAGTCAATCATAACCCGTTCAGTAAAGGAGAAAAGCACATGATCCAGGGCCAGGGAATTTCAGCCGCCGGGACTTCAT
AAAAATATCGTCGATTTTCC

Downstream 100 bases:

>100_bases
CGCGTGAGCAACAAAAAAAGCTATGGAATGGTCATCGACACCAGGGTCTGCGTCGCCTGCTCAGCCTGTGTCTATGCATG
TAAATCAGAAAACGGCATAC

Product: formate dehydrogenase

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: Sulfur reductase chain A [H]

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MQDQAHSQPGAVQAFSGRNSAVSGESGEKVVYSICEHCFWRCGIAAHVRDGKVYKITGSEHHPLSQGKLCPRGTGGIGQL
YDPDRLAHPLIRETRGGKQYYRKATWDEAVGVVAEKLYKTSQTYGPGSIAMLHHGYGVSFFKKMLSEIGVNKIAKPSYDL
CCGPARQAAVLTYGYPSDTPEGFDMMNSKYMIFFGTHFGENMHNTAVQEISEGIRRGAKIVVFDPRFSTLAGKADHWLPI
KPATDIAMMQGLMHVLISEEIYDKAFVEAHTVGFGELWESVREMTPEKVSAITDIPADAIRTVAREYAFHAPAAFVHSGR
RTNWYGDALQRLRAIHILNALVGNFKMPGGVVAFEKFPLVQPPAAHEHPAYEKEVYSKYPFFPNDEPSNTIASHEIVQQA
ISGEVKALVIYGVNLPETMTLGRKAAIEALEKVDFMVAIDVLPAEVTGYADVVLPECTYLERYDDLDNGRAFRTPFVALR
QPAVPPMYESKPGNQIAKMITDKWGLHGVFAPTVEAGLNKKLGLIGSSLEEIKKKGVLVMPATDLYRKPGEALNLKTPSG
KIELASEQLKTGGFDAVPTYTAHPEPPAGFYRMLTGRKPMLTFGRTANNRFLGDLATAKENEVWVNEQIAGKHNITNGEY
VHLKNQDGVISQFPVKVKVTQRIRPDAVYMVHGFGHTSAKLTWAYKRGASHNQLITRTEIDPAMGAVGFQNNFVTFIKEA

Sequences:

>Translated_720_residues
MQDQAHSQPGAVQAFSGRNSAVSGESGEKVVYSICEHCFWRCGIAAHVRDGKVYKITGSEHHPLSQGKLCPRGTGGIGQL
YDPDRLAHPLIRETRGGKQYYRKATWDEAVGVVAEKLYKTSQTYGPGSIAMLHHGYGVSFFKKMLSEIGVNKIAKPSYDL
CCGPARQAAVLTYGYPSDTPEGFDMMNSKYMIFFGTHFGENMHNTAVQEISEGIRRGAKIVVFDPRFSTLAGKADHWLPI
KPATDIAMMQGLMHVLISEEIYDKAFVEAHTVGFGELWESVREMTPEKVSAITDIPADAIRTVAREYAFHAPAAFVHSGR
RTNWYGDALQRLRAIHILNALVGNFKMPGGVVAFEKFPLVQPPAAHEHPAYEKEVYSKYPFFPNDEPSNTIASHEIVQQA
ISGEVKALVIYGVNLPETMTLGRKAAIEALEKVDFMVAIDVLPAEVTGYADVVLPECTYLERYDDLDNGRAFRTPFVALR
QPAVPPMYESKPGNQIAKMITDKWGLHGVFAPTVEAGLNKKLGLIGSSLEEIKKKGVLVMPATDLYRKPGEALNLKTPSG
KIELASEQLKTGGFDAVPTYTAHPEPPAGFYRMLTGRKPMLTFGRTANNRFLGDLATAKENEVWVNEQIAGKHNITNGEY
VHLKNQDGVISQFPVKVKVTQRIRPDAVYMVHGFGHTSAKLTWAYKRGASHNQLITRTEIDPAMGAVGFQNNFVTFIKEA
>Mature_720_residues
MQDQAHSQPGAVQAFSGRNSAVSGESGEKVVYSICEHCFWRCGIAAHVRDGKVYKITGSEHHPLSQGKLCPRGTGGIGQL
YDPDRLAHPLIRETRGGKQYYRKATWDEAVGVVAEKLYKTSQTYGPGSIAMLHHGYGVSFFKKMLSEIGVNKIAKPSYDL
CCGPARQAAVLTYGYPSDTPEGFDMMNSKYMIFFGTHFGENMHNTAVQEISEGIRRGAKIVVFDPRFSTLAGKADHWLPI
KPATDIAMMQGLMHVLISEEIYDKAFVEAHTVGFGELWESVREMTPEKVSAITDIPADAIRTVAREYAFHAPAAFVHSGR
RTNWYGDALQRLRAIHILNALVGNFKMPGGVVAFEKFPLVQPPAAHEHPAYEKEVYSKYPFFPNDEPSNTIASHEIVQQA
ISGEVKALVIYGVNLPETMTLGRKAAIEALEKVDFMVAIDVLPAEVTGYADVVLPECTYLERYDDLDNGRAFRTPFVALR
QPAVPPMYESKPGNQIAKMITDKWGLHGVFAPTVEAGLNKKLGLIGSSLEEIKKKGVLVMPATDLYRKPGEALNLKTPSG
KIELASEQLKTGGFDAVPTYTAHPEPPAGFYRMLTGRKPMLTFGRTANNRFLGDLATAKENEVWVNEQIAGKHNITNGEY
VHLKNQDGVISQFPVKVKVTQRIRPDAVYMVHGFGHTSAKLTWAYKRGASHNQLITRTEIDPAMGAVGFQNNFVTFIKEA

Specific function: Component of the phosphorylative electron transport system with polysulfide as the terminal acceptor [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081797, Length=740, Percent_Identity=26.4864864864865, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI1787870, Length=774, Percent_Identity=26.4857881136951, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI171474008, Length=745, Percent_Identity=26.0402684563758, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI3868721, Length=507, Percent_Identity=27.810650887574, Blast_Score=152, Evalue=9e-38,
Organism=Escherichia coli, GI3868720, Length=403, Percent_Identity=24.0694789081886, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI3868719, Length=272, Percent_Identity=24.6323529411765, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788534, Length=528, Percent_Identity=21.5909090909091, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787741, Length=276, Percent_Identity=24.6376811594203, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081994, Length=345, Percent_Identity=22.6086956521739, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR019546 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10518 TAT_signal [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 79480; Mature: 79480

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDQAHSQPGAVQAFSGRNSAVSGESGEKVVYSICEHCFWRCGIAAHVRDGKVYKITGSE
CCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCC
HHPLSQGKLCPRGTGGIGQLYDPDRLAHPLIRETRGGKQYYRKATWDEAVGVVAEKLYKT
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHH
SQTYGPGSIAMLHHGYGVSFFKKMLSEIGVNKIAKPSYDLCCGPARQAAVLTYGYPSDTP
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
EGFDMMNSKYMIFFGTHFGENMHNTAVQEISEGIRRGAKIVVFDPRFSTLAGKADHWLPI
CCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCEECC
KPATDIAMMQGLMHVLISEEIYDKAFVEAHTVGFGELWESVREMTPEKVSAITDIPADAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCHHHH
RTVAREYAFHAPAAFVHSGRRTNWYGDALQRLRAIHILNALVGNFKMPGGVVAFEKFPLV
HHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
QPPAAHEHPAYEKEVYSKYPFFPNDEPSNTIASHEIVQQAISGEVKALVIYGVNLPETMT
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
LGRKAAIEALEKVDFMVAIDVLPAEVTGYADVVLPECTYLERYDDLDNGRAFRTPFVALR
CCHHHHHHHHHHHCEEEEEEECCCCCCCCCCEECCCCHHHHHHCCCCCCCEECCCHHHHC
QPAVPPMYESKPGNQIAKMITDKWGLHGVFAPTVEAGLNKKLGLIGSSLEEIKKKGVLVM
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEECHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
PATDLYRKPGEALNLKTPSGKIELASEQLKTGGFDAVPTYTAHPEPPAGFYRMLTGRKPM
ECHHHHHCCCCEEEEECCCCCEEECHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCE
LTFGRTANNRFLGDLATAKENEVWVNEQIAGKHNITNGEYVHLKNQDGVISQFPVKVKVT
EEECCCCCCCEEHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCHHHCCEEEEEE
QRIRPDAVYMVHGFGHTSAKLTWAYKRGASHNQLITRTEIDPAMGAVGFQNNFVTFIKEA
CCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCCHHHCCCCCCCCCEEEEECC
>Mature Secondary Structure
MQDQAHSQPGAVQAFSGRNSAVSGESGEKVVYSICEHCFWRCGIAAHVRDGKVYKITGSE
CCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCC
HHPLSQGKLCPRGTGGIGQLYDPDRLAHPLIRETRGGKQYYRKATWDEAVGVVAEKLYKT
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHH
SQTYGPGSIAMLHHGYGVSFFKKMLSEIGVNKIAKPSYDLCCGPARQAAVLTYGYPSDTP
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
EGFDMMNSKYMIFFGTHFGENMHNTAVQEISEGIRRGAKIVVFDPRFSTLAGKADHWLPI
CCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCEECC
KPATDIAMMQGLMHVLISEEIYDKAFVEAHTVGFGELWESVREMTPEKVSAITDIPADAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCHHHH
RTVAREYAFHAPAAFVHSGRRTNWYGDALQRLRAIHILNALVGNFKMPGGVVAFEKFPLV
HHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
QPPAAHEHPAYEKEVYSKYPFFPNDEPSNTIASHEIVQQAISGEVKALVIYGVNLPETMT
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
LGRKAAIEALEKVDFMVAIDVLPAEVTGYADVVLPECTYLERYDDLDNGRAFRTPFVALR
CCHHHHHHHHHHHCEEEEEEECCCCCCCCCCEECCCCHHHHHHCCCCCCCEECCCHHHHC
QPAVPPMYESKPGNQIAKMITDKWGLHGVFAPTVEAGLNKKLGLIGSSLEEIKKKGVLVM
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEECHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
PATDLYRKPGEALNLKTPSGKIELASEQLKTGGFDAVPTYTAHPEPPAGFYRMLTGRKPM
ECHHHHHCCCCEEEEECCCCCEEECHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCE
LTFGRTANNRFLGDLATAKENEVWVNEQIAGKHNITNGEYVHLKNQDGVISQFPVKVKVT
EEECCCCCCCEEHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCHHHCCEEEEEE
QRIRPDAVYMVHGFGHTSAKLTWAYKRGASHNQLITRTEIDPAMGAVGFQNNFVTFIKEA
CCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCCHHHCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1597189; 14500908 [H]