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The map label for this gene is wecB [H]

Identifier: 119358321

GI number: 119358321

Start: 2929129

End: 2930280

Strand: Reverse

Name: wecB [H]

Synonym: Cpha266_2553

Alternate gene names: 119358321

Gene position: 2930280-2929129 (Counterclockwise)

Preceding gene: 119358323

Following gene: 119358320

Centisome position: 93.5

GC content: 53.56

Gene sequence:

>1152_bases
TTGAGGAAAATAATTTATTCTAATGTACTAAAGCTTTATGCAGTGAAAAAAGTCCTATTGACTGCCGGCGGACGTTCCGG
CGCTCTTTTACTCGCTCCGTTGTACCATGCCTTGAAAAAAAAGGGGTGCTGTGAGCCGATCGCATGTTTTGCCGCAGGGG
CTGGCGAAGAGTTGCTCTCTGCGGAGGTTGCGGCCTGTTTTTCGATGGTCGGCGCGGATCGTGCCATTCTGTTGTCGCAA
GACTCTTCTTCCGGTCGTCTTGCCGAAGTTCTGACCGGGATGGAGCGGATTATTGTGCTTGAAAAGCCGGATCTGGTGAT
GGTGTTCGGCAATGATGCCGCGGCGTTGGGCGCTGCCGTTGCCTCTGTGCAGTGCGGCGTTTCTGTCGCATCGGTCGATG
CTGGTTTGCGGAGCAATGATCTTGCCGATTCGGGCGAGAGGTGCCGTCGTATGATTGATGCTGCGGCGTCGCTGCATCTT
GTCAGCGAGCATAGCGGCGAGTATAATCTGATCAGCGAGGGTATTATCGAAGAGGATATTTTTTTTGCGGGTAATCTTGC
AATCGACTCTCTTGCCGTTCTGATGCCTGAGGCAAACAAGCGGGCTGTTTGCGGCGATTTTGGCGTTGATCCTAAAAAGT
TCGCATTGGTTCTTTTGCAGGGTCCGGCGCTTTTTTCCGGCAGGGAGTCTCTTGAGATGCTGCTTGGATTGCTTCGGGGC
CTTGCCGGAAAAAGCGAGCTTCTTATGCCGCTCAGCCCCGCTTTTGATGCGGCTCTCTCTCTTTACGGGTTGCGTGGTGC
GTTTGGTGAGGTGCCGGGACTGCGTCTGATCGGGCATCCCGGCTATATCGAGCTCCTGGGTCTGCTCAGGGATGCCTCTT
TTCTGCTTGTCGATACGGAAGACCTGCAGCCTGAGGCTACGGTGATGAGCGTGCCCTGCCTTTCCATGATGGAGGTTACC
TCCCGCCCTTCAACCATAGAGATCGGCACCAATATATTGGTCGGTATGGATGAGGATGATGTCTGGAGCAGGGCGGATGA
TGTTTTGCGTCTGCATGCGCATTCAGGGTTGTCGAAACGATCGAAAATTCCTGAAAAATGGGATGGTCAGGCTGCGCAAC
GCATTGTCGAACTGCTTGAGAGGATATTGTAG

Upstream 100 bases:

>100_bases
CTGTTTGACGATCTGATCGCTTCGCTTTGGCGATGCTTGTAATCAGTTCGGAGCTGTCGGTATTTTCGACGGTTATCAGC
AGCGCCCAGGTGATACCCTT

Downstream 100 bases:

>100_bases
GGTTTCTTGCAGATGCCTTCGATCGTGGCGTTTGCTTATCGGTGAGAGGGAACTCTCATTATGGTTTGGGAGTTTAAGCT
GCCAGTTGATCCGCTGTTTT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRKIIYSNVLKLYAVKKVLLTAGGRSGALLLAPLYHALKKKGCCEPIACFAAGAGEELLSAEVAACFSMVGADRAILLSQ
DSSSGRLAEVLTGMERIIVLEKPDLVMVFGNDAAALGAAVASVQCGVSVASVDAGLRSNDLADSGERCRRMIDAAASLHL
VSEHSGEYNLISEGIIEEDIFFAGNLAIDSLAVLMPEANKRAVCGDFGVDPKKFALVLLQGPALFSGRESLEMLLGLLRG
LAGKSELLMPLSPAFDAALSLYGLRGAFGEVPGLRLIGHPGYIELLGLLRDASFLLVDTEDLQPEATVMSVPCLSMMEVT
SRPSTIEIGTNILVGMDEDDVWSRADDVLRLHAHSGLSKRSKIPEKWDGQAAQRIVELLERIL

Sequences:

>Translated_383_residues
MRKIIYSNVLKLYAVKKVLLTAGGRSGALLLAPLYHALKKKGCCEPIACFAAGAGEELLSAEVAACFSMVGADRAILLSQ
DSSSGRLAEVLTGMERIIVLEKPDLVMVFGNDAAALGAAVASVQCGVSVASVDAGLRSNDLADSGERCRRMIDAAASLHL
VSEHSGEYNLISEGIIEEDIFFAGNLAIDSLAVLMPEANKRAVCGDFGVDPKKFALVLLQGPALFSGRESLEMLLGLLRG
LAGKSELLMPLSPAFDAALSLYGLRGAFGEVPGLRLIGHPGYIELLGLLRDASFLLVDTEDLQPEATVMSVPCLSMMEVT
SRPSTIEIGTNILVGMDEDDVWSRADDVLRLHAHSGLSKRSKIPEKWDGQAAQRIVELLERIL
>Mature_383_residues
MRKIIYSNVLKLYAVKKVLLTAGGRSGALLLAPLYHALKKKGCCEPIACFAAGAGEELLSAEVAACFSMVGADRAILLSQ
DSSSGRLAEVLTGMERIIVLEKPDLVMVFGNDAAALGAAVASVQCGVSVASVDAGLRSNDLADSGERCRRMIDAAASLHL
VSEHSGEYNLISEGIIEEDIFFAGNLAIDSLAVLMPEANKRAVCGDFGVDPKKFALVLLQGPALFSGRESLEMLLGLLRG
LAGKSELLMPLSPAFDAALSLYGLRGAFGEVPGLRLIGHPGYIELLGLLRDASFLLVDTEDLQPEATVMSVPCLSMMEVT
SRPSTIEIGTNILVGMDEDDVWSRADDVLRLHAHSGLSKRSKIPEKWDGQAAQRIVELLERIL

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=373, Percent_Identity=27.6139410187668, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40764; Mature: 40764

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIYSNVLKLYAVKKVLLTAGGRSGALLLAPLYHALKKKGCCEPIACFAAGAGEELLS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHH
AEVAACFSMVGADRAILLSQDSSSGRLAEVLTGMERIIVLEKPDLVMVFGNDAAALGAAV
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCHHEEEEEECCCEEEEECCCHHHHHHHH
ASVQCGVSVASVDAGLRSNDLADSGERCRRMIDAAASLHLVSEHSGEYNLISEGIIEEDI
HHHHCCCEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEHHHCCCHHHHH
FFAGNLAIDSLAVLMPEANKRAVCGDFGVDPKKFALVLLQGPALFSGRESLEMLLGLLRG
EEECCHHHHHHHHCCCCCCCCEECCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHC
LAGKSELLMPLSPAFDAALSLYGLRGAFGEVPGLRLIGHPGYIELLGLLRDASFLLVDTE
CCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCEEEEECC
DLQPEATVMSVPCLSMMEVTSRPSTIEIGTNILVGMDEDDVWSRADDVLRLHAHSGLSKR
CCCCCCEEEECCHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCHHH
SKIPEKWDGQAAQRIVELLERIL
HCCCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MRKIIYSNVLKLYAVKKVLLTAGGRSGALLLAPLYHALKKKGCCEPIACFAAGAGEELLS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHH
AEVAACFSMVGADRAILLSQDSSSGRLAEVLTGMERIIVLEKPDLVMVFGNDAAALGAAV
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCHHEEEEEECCCEEEEECCCHHHHHHHH
ASVQCGVSVASVDAGLRSNDLADSGERCRRMIDAAASLHLVSEHSGEYNLISEGIIEEDI
HHHHCCCEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEHHHCCCHHHHH
FFAGNLAIDSLAVLMPEANKRAVCGDFGVDPKKFALVLLQGPALFSGRESLEMLLGLLRG
EEECCHHHHHHHHCCCCCCCCEECCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHC
LAGKSELLMPLSPAFDAALSLYGLRGAFGEVPGLRLIGHPGYIELLGLLRDASFLLVDTE
CCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCEEEEECC
DLQPEATVMSVPCLSMMEVTSRPSTIEIGTNILVGMDEDDVWSRADDVLRLHAHSGLSKR
CCCCCCEEEECCHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCHHH
SKIPEKWDGQAAQRIVELLERIL
HCCCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA