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The map label for this gene is fabD [H]

Identifier: 119358259

GI number: 119358259

Start: 2858386

End: 2859294

Strand: Direct

Name: fabD [H]

Synonym: Cpha266_2491

Alternate gene names: 119358259

Gene position: 2858386-2859294 (Clockwise)

Preceding gene: 119358258

Following gene: 119358260

Centisome position: 91.21

GC content: 52.37

Gene sequence:

>909_bases
ATGAAAGCATTTCTATTTCCAGGACAGGGATCTCAATATTGCGGCATGGGCAAGGATATTTTCGAAACCTATCCTGCTGC
GCGTTCAATGATGGAAAAAGCCAACGAGCTTCTCGGGTATTCCATCACCGATATCATGTTTTCGGGTAGCGAGGAAAAAC
TTCGGCAGACCCAGTATACCCAGCCCTCTATTTTCCTGCACAGCATTGTTGCCGCATCGCTGCTCGGTCGAAAGGACGTT
ATCATGACCGCGGGCCACAGCCTTGGCGAATATACCGCGCTCTGCTATGCCGGCGCACTCTCTTTTGACGACACCATCCG
CCTGGTCGCAAAACGTGGCGAACTGATGCAGAAAGCAGGAGAAATACATCCCGGCACCATGGCCGCCATAATCGGCATGC
CGGACAGCGCTCTTGAAGATCTGCTGCTTGAAGCCGGAACGGAAGGCATTGTACAGGCGGCAAACTTCAACTCGCCCGGT
CAGATCGTTATTTCCGGAGATATTGCAGCGGTCAGAAAAGCCATCGCGCTGGCACCGTCAAAAGGGTCAAGAATGGCAAA
GGAGCTGGTCGTATCCGGAGCCTTCCACTCCCCGCTTATGAAACCGGCCGAAGTAGAGCTTGCCGCCGCACTTGATCTGG
TTGAGATCAGGGATGCCGAAATACCGGTATGCATGAACGCCATAGCCGCCCCGGTCACCATTGCCGGCGAAATAAGAAAA
AATCTGATCCTGCAACTCACCAGCTCGGTACTCTGGACTCAATCAATTCAAACTATGGTTGGCAGCGGCGTTACTGAATT
TATTGAAGTCGGCCCTCAGAAAGTGCTGCAGGGGCTGATCAAGCGAATAGATAAATCAGTGAAAACCGGAGGCATCGACA
CCGCTCAAGAGTTGCAGCAATGTCTTTGA

Upstream 100 bases:

>100_bases
ATCTGGTACTTGTCAGTTTCGGAGCAGGCTATACCTGGGGCGGCATCTATATAAAATGGCAATAATAACAGGTCACTGTA
TTTGTTAAAACACTGCATTC

Downstream 100 bases:

>100_bases
TTGTCCCCGAACAGCTCATGAAACATCAACAGAACATCTCATTATGCTTAAAGGAAAAATTGCCGTCATAACCGGTGCTG
CCAGAGGAATAGGACAAGCT

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKAFLFPGQGSQYCGMGKDIFETYPAARSMMEKANELLGYSITDIMFSGSEEKLRQTQYTQPSIFLHSIVAASLLGRKDV
IMTAGHSLGEYTALCYAGALSFDDTIRLVAKRGELMQKAGEIHPGTMAAIIGMPDSALEDLLLEAGTEGIVQAANFNSPG
QIVISGDIAAVRKAIALAPSKGSRMAKELVVSGAFHSPLMKPAEVELAAALDLVEIRDAEIPVCMNAIAAPVTIAGEIRK
NLILQLTSSVLWTQSIQTMVGSGVTEFIEVGPQKVLQGLIKRIDKSVKTGGIDTAQELQQCL

Sequences:

>Translated_302_residues
MKAFLFPGQGSQYCGMGKDIFETYPAARSMMEKANELLGYSITDIMFSGSEEKLRQTQYTQPSIFLHSIVAASLLGRKDV
IMTAGHSLGEYTALCYAGALSFDDTIRLVAKRGELMQKAGEIHPGTMAAIIGMPDSALEDLLLEAGTEGIVQAANFNSPG
QIVISGDIAAVRKAIALAPSKGSRMAKELVVSGAFHSPLMKPAEVELAAALDLVEIRDAEIPVCMNAIAAPVTIAGEIRK
NLILQLTSSVLWTQSIQTMVGSGVTEFIEVGPQKVLQGLIKRIDKSVKTGGIDTAQELQQCL
>Mature_302_residues
MKAFLFPGQGSQYCGMGKDIFETYPAARSMMEKANELLGYSITDIMFSGSEEKLRQTQYTQPSIFLHSIVAASLLGRKDV
IMTAGHSLGEYTALCYAGALSFDDTIRLVAKRGELMQKAGEIHPGTMAAIIGMPDSALEDLLLEAGTEGIVQAANFNSPG
QIVISGDIAAVRKAIALAPSKGSRMAKELVVSGAFHSPLMKPAEVELAAALDLVEIRDAEIPVCMNAIAAPVTIAGEIRK
NLILQLTSSVLWTQSIQTMVGSGVTEFIEVGPQKVLQGLIKRIDKSVKTGGIDTAQELQQCL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=317, Percent_Identity=33.7539432176656, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=37.3831775700935, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787334, Length=294, Percent_Identity=40.1360544217687, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71984332, Length=289, Percent_Identity=31.8339100346021, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=27.9310344827586, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=36.241610738255, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32220; Mature: 32220

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFLFPGQGSQYCGMGKDIFETYPAARSMMEKANELLGYSITDIMFSGSEEKLRQTQYT
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHCCC
QPSIFLHSIVAASLLGRKDVIMTAGHSLGEYTALCYAGALSFDDTIRLVAKRGELMQKAG
CHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
EIHPGTMAAIIGMPDSALEDLLLEAGTEGIVQAANFNSPGQIVISGDIAAVRKAIALAPS
CCCCCCEEEEECCCHHHHHHHHHHCCCCHHEEECCCCCCCEEEEECCHHHHHHHHHCCCC
KGSRMAKELVVSGAFHSPLMKPAEVELAAALDLVEIRDAEIPVCMNAIAAPVTIAGEIRK
CCHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHH
NLILQLTSSVLWTQSIQTMVGSGVTEFIEVGPQKVLQGLIKRIDKSVKTGGIDTAQELQQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
CL
HC
>Mature Secondary Structure
MKAFLFPGQGSQYCGMGKDIFETYPAARSMMEKANELLGYSITDIMFSGSEEKLRQTQYT
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHCCC
QPSIFLHSIVAASLLGRKDVIMTAGHSLGEYTALCYAGALSFDDTIRLVAKRGELMQKAG
CHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
EIHPGTMAAIIGMPDSALEDLLLEAGTEGIVQAANFNSPGQIVISGDIAAVRKAIALAPS
CCCCCCEEEEECCCHHHHHHHHHHCCCCHHEEECCCCCCCEEEEECCHHHHHHHHHCCCC
KGSRMAKELVVSGAFHSPLMKPAEVELAAALDLVEIRDAEIPVCMNAIAAPVTIAGEIRK
CCHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHH
NLILQLTSSVLWTQSIQTMVGSGVTEFIEVGPQKVLQGLIKRIDKSVKTGGIDTAQELQQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
CL
HC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]