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The map label for this gene is carA [H]

Identifier: 119358227

GI number: 119358227

Start: 2832554

End: 2833663

Strand: Direct

Name: carA [H]

Synonym: Cpha266_2459

Alternate gene names: 119358227

Gene position: 2832554-2833663 (Clockwise)

Preceding gene: 119358226

Following gene: 119358228

Centisome position: 90.38

GC content: 50.36

Gene sequence:

>1110_bases
ATGCACGTGACACCAGCAACATTGGTTTTGGAAAACGGATCCGTCTATAAAGGGACGGCGTTCGGACATATCGGAGAGGC
TGTCGGCGAAGTGGTTTTCAACACATCGCTTACGGGATATCAGGAAATTCTTACCGACCCATCATATGCCGGGCAAATGA
TTGTGATGACCTATCCCCTGATCGGCAATTACGGCATCAATCCCAATGATAACGAGTCATCGAGGATATGGGCCTCAGCA
CTCATTGTAAAGGAAGTATCGACTATCCACAGCAATTATGAGGCGACGATCAGTCTCGACGCCTGGCTGAAAGAGTCAAA
AGTCATGGGGCTTGCCGGCATCGACACACGCAGGCTCGTTCGCGAAATCCGCGAAAAGGGCGCCATGAGGGGCGTAATTT
CAACCTTTGACCTTTCAAATGAAGCGCTGCAGCAAAAGGCGCTCAGCATACCTGAGATGACTGGAAACGATCTGGTTAAA
ACCGTTACGACCAGTGAAAACTATGAACTGAAACGCCCCGACGCGCGTTACCACGTTGTCGCTTTCGATTACGGCATCAA
AAGCAATATTCTTCGAATTCTGCAGAACGCAGGGTGCAGGGTTACCGTACTCACTGCTGCGACAACGGCTGAAGAGGTTA
TAAAACTTAATCCTGACGGCGTTTTTCTTTCAAACGGCCCGGGCGATCCGTCCGCTGTTGATTATGCCGTTGCAACCATT
CGGGAACTGGCCCAATACAGCCAATCGACGCGACCGCTGCCGATTTTCGGCATCTGCCTCGGTCATCAGCTTCTCGCTCT
CGCTTTTGGCGCCGAAACCTACAAGCTCAAATTCGGGCATCACGGCAGCAATCATCCGGTCAAAAACATTTCGACAAGCA
AAATCGAGATCACATCACAGAATCATGGATTTGCCGTAAAGATGGACACGCTCCCGGAAAAACTTTCATTGACCCACGTC
AATCTTTACGACCATACCGTCGAGGGAATACGACACCGTGAACTGCCCTGTTTTTCTGTACAGTATCATCCGGAAGCCGC
GCCGGGGCCGCATGATTCGCACTATCTTTTCGATGAATTCACTGCACTGATGGACCAGGCAAAAAACTGA

Upstream 100 bases:

>100_bases
TAAGCGAAAATGTTAAAATCAAATTCGACCGGACGGCTGTTGCGAACATCGAAAAACAGGAAACCGGCGACAAACTTGCT
ACGAAGGAATAAACAGCATC

Downstream 100 bases:

>100_bases
CCCTCCCGTGCTGGAGACAGGATATTTCTCTTTATTGTTCAAGCAATCTCTTTAACTACCAAACCATTTTCTGAAGAGAT
GAAAAAAAGATTGTTCACTC

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MHVTPATLVLENGSVYKGTAFGHIGEAVGEVVFNTSLTGYQEILTDPSYAGQMIVMTYPLIGNYGINPNDNESSRIWASA
LIVKEVSTIHSNYEATISLDAWLKESKVMGLAGIDTRRLVREIREKGAMRGVISTFDLSNEALQQKALSIPEMTGNDLVK
TVTTSENYELKRPDARYHVVAFDYGIKSNILRILQNAGCRVTVLTAATTAEEVIKLNPDGVFLSNGPGDPSAVDYAVATI
RELAQYSQSTRPLPIFGICLGHQLLALAFGAETYKLKFGHHGSNHPVKNISTSKIEITSQNHGFAVKMDTLPEKLSLTHV
NLYDHTVEGIRHRELPCFSVQYHPEAAPGPHDSHYLFDEFTALMDQAKN

Sequences:

>Translated_369_residues
MHVTPATLVLENGSVYKGTAFGHIGEAVGEVVFNTSLTGYQEILTDPSYAGQMIVMTYPLIGNYGINPNDNESSRIWASA
LIVKEVSTIHSNYEATISLDAWLKESKVMGLAGIDTRRLVREIREKGAMRGVISTFDLSNEALQQKALSIPEMTGNDLVK
TVTTSENYELKRPDARYHVVAFDYGIKSNILRILQNAGCRVTVLTAATTAEEVIKLNPDGVFLSNGPGDPSAVDYAVATI
RELAQYSQSTRPLPIFGICLGHQLLALAFGAETYKLKFGHHGSNHPVKNISTSKIEITSQNHGFAVKMDTLPEKLSLTHV
NLYDHTVEGIRHRELPCFSVQYHPEAAPGPHDSHYLFDEFTALMDQAKN
>Mature_369_residues
MHVTPATLVLENGSVYKGTAFGHIGEAVGEVVFNTSLTGYQEILTDPSYAGQMIVMTYPLIGNYGINPNDNESSRIWASA
LIVKEVSTIHSNYEATISLDAWLKESKVMGLAGIDTRRLVREIREKGAMRGVISTFDLSNEALQQKALSIPEMTGNDLVK
TVTTSENYELKRPDARYHVVAFDYGIKSNILRILQNAGCRVTVLTAATTAEEVIKLNPDGVFLSNGPGDPSAVDYAVATI
RELAQYSQSTRPLPIFGICLGHQLLALAFGAETYKLKFGHHGSNHPVKNISTSKIEITSQNHGFAVKMDTLPEKLSLTHV
NLYDHTVEGIRHRELPCFSVQYHPEAAPGPHDSHYLFDEFTALMDQAKN

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=373, Percent_Identity=41.5549597855228, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI21361331, Length=374, Percent_Identity=37.7005347593583, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI169790915, Length=374, Percent_Identity=37.7005347593583, Blast_Score=243, Evalue=2e-64,
Organism=Escherichia coli, GI1786215, Length=382, Percent_Identity=50.261780104712, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1789760, Length=148, Percent_Identity=30.4054054054054, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=376, Percent_Identity=41.4893617021277, Blast_Score=273, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6324878, Length=370, Percent_Identity=40.5405405405405, Blast_Score=256, Evalue=5e-69,
Organism=Saccharomyces cerevisiae, GI6322331, Length=396, Percent_Identity=37.6262626262626, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6322638, Length=180, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45555749, Length=385, Percent_Identity=39.7402597402597, Blast_Score=260, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24642586, Length=385, Percent_Identity=39.7402597402597, Blast_Score=260, Evalue=9e-70,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40562; Mature: 40562

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVTPATLVLENGSVYKGTAFGHIGEAVGEVVFNTSLTGYQEILTDPSYAGQMIVMTYPL
CCCCCEEEEEECCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECE
IGNYGINPNDNESSRIWASALIVKEVSTIHSNYEATISLDAWLKESKVMGLAGIDTRRLV
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCEEEEECCCHHHHH
REIREKGAMRGVISTFDLSNEALQQKALSIPEMTGNDLVKTVTTSENYELKRPDARYHVV
HHHHHCCHHHHHHHEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCEECCCCCCEEEE
AFDYGIKSNILRILQNAGCRVTVLTAATTAEEVIKLNPDGVFLSNGPGDPSAVDYAVATI
EEECCCHHHHHHHHHCCCCEEEEEEECCCCCHHEEECCCEEEEECCCCCCHHHHHHHHHH
RELAQYSQSTRPLPIFGICLGHQLLALAFGAETYKLKFGHHGSNHPVKNISTSKIEITSQ
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEC
NHGFAVKMDTLPEKLSLTHVNLYDHTVEGIRHRELPCFSVQYHPEAAPGPHDSHYLFDEF
CCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHH
TALMDQAKN
HHHHHHCCC
>Mature Secondary Structure
MHVTPATLVLENGSVYKGTAFGHIGEAVGEVVFNTSLTGYQEILTDPSYAGQMIVMTYPL
CCCCCEEEEEECCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECE
IGNYGINPNDNESSRIWASALIVKEVSTIHSNYEATISLDAWLKESKVMGLAGIDTRRLV
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCEEEEECCCHHHHH
REIREKGAMRGVISTFDLSNEALQQKALSIPEMTGNDLVKTVTTSENYELKRPDARYHVV
HHHHHCCHHHHHHHEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCEECCCCCCEEEE
AFDYGIKSNILRILQNAGCRVTVLTAATTAEEVIKLNPDGVFLSNGPGDPSAVDYAVATI
EEECCCHHHHHHHHHCCCCEEEEEEECCCCCHHEEECCCEEEEECCCCCCHHHHHHHHHH
RELAQYSQSTRPLPIFGICLGHQLLALAFGAETYKLKFGHHGSNHPVKNISTSKIEITSQ
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEC
NHGFAVKMDTLPEKLSLTHVNLYDHTVEGIRHRELPCFSVQYHPEAAPGPHDSHYLFDEF
CCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHH
TALMDQAKN
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA