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The map label for this gene is gcp

Identifier: 119358225

GI number: 119358225

Start: 2831068

End: 2832129

Strand: Direct

Name: gcp

Synonym: Cpha266_2457

Alternate gene names: 119358225

Gene position: 2831068-2832129 (Clockwise)

Preceding gene: 119358214

Following gene: 119358226

Centisome position: 90.34

GC content: 51.32

Gene sequence:

>1062_bases
ATGAAAATATTAGGAATCGAGACCAGTTGCGACGAAACGTCAGCGGCAGTACTTTCCAACGGAAGCGTATGCTCGAACAT
TGTCAGTTCACAGCTATGCCATACCAGCTTCGGAGGCGTTGTTCCCGAGTTGGCGTCAAGAGAACACGAGCGGCTGATCG
TTTCGATTGTCGATAGCGCACTCAGTGAAGCCAATATAACAAAAAACGATCTCGATGTCATAGCAGCCACCGCCGGCCCG
GGGCTTATAGGCGCCGTGATGGTCGGGTTGTGTTTCGGCCAGGCAATGGCTTATGCGCTTGCTATACCGTTTGTACCCGT
CAATCATATTGAAGCGCATATTTTTTCCGCTTTCATTCAGGAAACCCCTCATCATCAGGCTCCCGAAGGTGATTTTATCT
CCCTGACGGTCTCCGGCGGCCACACGCTGCTGTCGCATGTCCATAAAGACTTCACCTATGAGGTTATCGGCAGAACCCTT
GACGATGCAGCAGGGGAAGCTTTCGATAAAACAGGGAAAATGCTTGGCCTGCCTTATCCGGCAGGACCGGTGATTGACCG
CCTTGCAAAAAACGGTGACCCCTTTTTTCACGAATTTCCCCGAGCGCTGACCGCTCACTCGCAAACCAGTAAAAACTATC
GCGGCAATTCTGATTTCAGTTTTTCAGGCCTTAAGACCTCCGTATTGACCTTTCTGAAAAAACAGTCGCCGGAATTCATC
GAAAAACACCTTCCTGACATTGCTGCCTCTGTCCAGAAGGCAATCGTCAGCGTGCTGGTTGAAAAAACCGTTTCCGCGGC
CCTTGCCGGAAACGTTAAAGCGATATCGATTGCAGGGGGAGTCAGTGCCAATTCAGCGCTGAGAACCTCCATGAAAAAGG
CTTGCGAACAGCATGGAATAGCCTTTCATGTTCCCAATGCCGAGTACTCGACCGACAATGCCGCCATGATCGCAACTCTC
GCAGGACTCCTGCTTGCGCATGACCTGGTGCCCCGAAACCGGTATAACATAGCTCCGTTTGCAAGTTTTGCCGCCGGTCG
CCGAAAGGCTTCATTGACATAA

Upstream 100 bases:

>100_bases
CAAGAATCAGAAGAAGATTGAAAAAACCGATCTTGACCTTCGGTTTGCTATTATTGCCCGGTTTATTAGCTTTGGCCATA
GGTATTCAGAAAAACGAACT

Downstream 100 bases:

>100_bases
TTGATGAAATACATTACATTACGGTTCGCTATAGAGCATTTAAACCATTGAACAACGAAATCATGTACCAGAGTTTTTTT
TCCCTCCTTCTGTTTTCTCC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKILGIETSCDETSAAVLSNGSVCSNIVSSQLCHTSFGGVVPELASREHERLIVSIVDSALSEANITKNDLDVIAATAGP
GLIGAVMVGLCFGQAMAYALAIPFVPVNHIEAHIFSAFIQETPHHQAPEGDFISLTVSGGHTLLSHVHKDFTYEVIGRTL
DDAAGEAFDKTGKMLGLPYPAGPVIDRLAKNGDPFFHEFPRALTAHSQTSKNYRGNSDFSFSGLKTSVLTFLKKQSPEFI
EKHLPDIAASVQKAIVSVLVEKTVSAALAGNVKAISIAGGVSANSALRTSMKKACEQHGIAFHVPNAEYSTDNAAMIATL
AGLLLAHDLVPRNRYNIAPFASFAAGRRKASLT

Sequences:

>Translated_353_residues
MKILGIETSCDETSAAVLSNGSVCSNIVSSQLCHTSFGGVVPELASREHERLIVSIVDSALSEANITKNDLDVIAATAGP
GLIGAVMVGLCFGQAMAYALAIPFVPVNHIEAHIFSAFIQETPHHQAPEGDFISLTVSGGHTLLSHVHKDFTYEVIGRTL
DDAAGEAFDKTGKMLGLPYPAGPVIDRLAKNGDPFFHEFPRALTAHSQTSKNYRGNSDFSFSGLKTSVLTFLKKQSPEFI
EKHLPDIAASVQKAIVSVLVEKTVSAALAGNVKAISIAGGVSANSALRTSMKKACEQHGIAFHVPNAEYSTDNAAMIATL
AGLLLAHDLVPRNRYNIAPFASFAAGRRKASLT
>Mature_353_residues
MKILGIETSCDETSAAVLSNGSVCSNIVSSQLCHTSFGGVVPELASREHERLIVSIVDSALSEANITKNDLDVIAATAGP
GLIGAVMVGLCFGQAMAYALAIPFVPVNHIEAHIFSAFIQETPHHQAPEGDFISLTVSGGHTLLSHVHKDFTYEVIGRTL
DDAAGEAFDKTGKMLGLPYPAGPVIDRLAKNGDPFFHEFPRALTAHSQTSKNYRGNSDFSFSGLKTSVLTFLKKQSPEFI
EKHLPDIAASVQKAIVSVLVEKTVSAALAGNVKAISIAGGVSANSALRTSMKKACEQHGIAFHVPNAEYSTDNAAMIATL
AGLLLAHDLVPRNRYNIAPFASFAAGRRKASLT

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=356, Percent_Identity=32.8651685393258, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI8923380, Length=325, Percent_Identity=29.5384615384615, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1789445, Length=320, Percent_Identity=40.9375, Blast_Score=244, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI71995670, Length=336, Percent_Identity=29.4642857142857, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17557464, Length=366, Percent_Identity=26.5027322404372, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=367, Percent_Identity=29.4277929155313, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6322891, Length=297, Percent_Identity=27.9461279461279, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129063, Length=360, Percent_Identity=30.2777777777778, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=28.7878787878788, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CHLPD (A1BJ68)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912869.1
- ProteinModelPortal:   A1BJ68
- SMR:   A1BJ68
- STRING:   A1BJ68
- MEROPS:   M22.001
- GeneID:   4568885
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2457
- NMPDR:   fig|290317.7.peg.2572
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37338; Mature: 37338

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILGIETSCDETSAAVLSNGSVCSNIVSSQLCHTSFGGVVPELASREHERLIVSIVDSA
CEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHH
LSEANITKNDLDVIAATAGPGLIGAVMVGLCFGQAMAYALAIPFVPVNHIEAHIFSAFIQ
HHHCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ETPHHQAPEGDFISLTVSGGHTLLSHVHKDFTYEVIGRTLDDAAGEAFDKTGKMLGLPYP
HCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
AGPVIDRLAKNGDPFFHEFPRALTAHSQTSKNYRGNSDFSFSGLKTSVLTFLKKQSPEFI
CCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
EKHLPDIAASVQKAIVSVLVEKTVSAALAGNVKAISIAGGVSANSALRTSMKKACEQHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
AFHVPNAEYSTDNAAMIATLAGLLLAHDLVPRNRYNIAPFASFAAGRRKASLT
EEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MKILGIETSCDETSAAVLSNGSVCSNIVSSQLCHTSFGGVVPELASREHERLIVSIVDSA
CEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHH
LSEANITKNDLDVIAATAGPGLIGAVMVGLCFGQAMAYALAIPFVPVNHIEAHIFSAFIQ
HHHCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ETPHHQAPEGDFISLTVSGGHTLLSHVHKDFTYEVIGRTLDDAAGEAFDKTGKMLGLPYP
HCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
AGPVIDRLAKNGDPFFHEFPRALTAHSQTSKNYRGNSDFSFSGLKTSVLTFLKKQSPEFI
CCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
EKHLPDIAASVQKAIVSVLVEKTVSAALAGNVKAISIAGGVSANSALRTSMKKACEQHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
AFHVPNAEYSTDNAAMIATLAGLLLAHDLVPRNRYNIAPFASFAAGRRKASLT
EEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA