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The map label for this gene is fcbD [H]

Identifier: 119358109

GI number: 119358109

Start: 2713816

End: 2715870

Strand: Reverse

Name: fcbD [H]

Synonym: Cpha266_2341

Alternate gene names: 119358109

Gene position: 2715870-2713816 (Counterclockwise)

Preceding gene: 119358110

Following gene: 119358108

Centisome position: 86.66

GC content: 33.48

Gene sequence:

>2055_bases
ATGTGCCTTCTTAAAGACGCTATAATACATTATAGTAATAAGGAGTATGAAAAAGCAAAAGAGCTTTTTCAAATAGCAGG
TGACAGATATGGAAAAAATGTTGTTGCTGCAAATATATATTTTTGTAATAAAGCTCTGAATGCTAATCATGCTGTGATTG
CGGACTCTTTTTCCAAAGAAAAGTCGTATATAAATAGTAGATTAGATCCTGCAACAATATTGATGCTGCATCAAAATGGC
GATATAGTTCTTGATGATGATCAAAAAAATGAATGTATTTTATTATACAATAAATTAACTGAGAGGAAGTCAGAAGATGC
TGACGTTAAAAAAATAGATCCTATACCAGCAGATTGGCCAACGGATCTTATATTATCGCCTATTCCCGAAAGTACGAATG
ATTTTTATTGGTATTTAGGTAGAAAAGCAAGAAAAAATAATAAATATTCACAAATTGGCCTGAGTGTAATTGTTCCTACC
TTTAATAGGAGTAGAATTCTTGATATCACATTGGCTTGCTTAGTGAATCAGGAGACGGAATATCCGTTTGAAATAGTAGT
TGCTGATGATGGAAGCAAGGAAGCTGTTATTGATATTGTAAAAAAATATGAGTCAATAATTGATATAAAATATATAAGAC
AAAAAGATTATGGTTATCAATTGTGTGCTGTTCGCAATTTAGGCTTGAGAGCAGCTAAGTATGAATTTGTTGCTATTTTG
GATTGCGATATGGCTCCAAATATTAAATGGGTGCAATCATACATGGAATTGCTTGTTGAAAATGATGATCTTGCTCTTAT
TGGTCCGCGAAAATATGTTGATACTAATGGTTTATCAGCATCATCGTTTCTTGATGATAAAAACCTTATAGAGTTATTGC
CGGAAGTGAAAACTAATAATAATGTTGCCGGAAAAGATATAGAAAGTATTTCAGTTGATTGGCGACTAGAGCATTTCAAT
CATACTCAAAATCTGAGATTATGTGATACTCCGTTCAGGTATTTTAGTGGCGGTAATGTTGCGTTTTCTCGAAAGTGGTT
AAATAAAGCAGGTTGGTTTGATGAGGAGTTTACGCAATGGGGAGGGGAAGATAATGAGTTTGGCTACCGTCTTTATCGTC
AAGGATGTTTTTTTCAGGCAGTTGCAGGCGGTATTGCTTATCATCAAGAACCACCAGGCAAGGAAAATGAAACCGACCGA
GCTGCGGGGAAGAAAGTTACAGTAAATCTTGTGCATGAAAAAGTTCCCTACTTTTACAGGAAATATGAATCGGATGAAAA
ATTTAAAATGTATAATGTTCCTTTAGTTTCTATATATATTCCGGCTTATAATTGTGAAAATTATATTGTACGTTGTGTTG
AGAGCGCATTGAATCAAACGATTACAGATCTTGAGGTATGTATTTGTAATGATGGATCTACTGACAATACTCTCGATGTT
CTCTATGATGCTTTTGGAAATAATCCTCGTGTTCATATTATAGATAAAAAAAACGGAGGGATTGGAAGTGCCTCAAACAC
TGCTGTACGCATGGCTAGGGGGTTTTATGTTGGACAACTTGATTCAGATGACTATTTAGAACCGGATGCTGTTGAACTTT
GTTTAAAAGAATTTTTAAGTGACAGAAGCCTTGTTTGCGTTTATACTACAAACAGAAATATTAAACCCGATGGTTCTATT
ATTGCTAAAGGATATAATTGGCCTCATTACTCGCGTGAAAAGATTTTAACCACGATGATAATTCATCATTTCAGAATGTT
TACTATACGTTCATGGAATCTAACCGATGGTTTTGATGAGCAAATGAGCAATGCTATTGATTATGATATGTTCTTAAAGT
TGAGTGAGGTTGGTAAATTCAAGCATATAAATAAAATATGTTATAATCGTCTTCTTCACGGCGAAAATACTTCTATTAAA
AATCTTTCCATTCAAAAGAAAAATCATTTTTTAGCAGTTAATAATTCTCTAAAACGTCAAGGGATCAATTGTTATACATA
TATTCCAAAAGAAGATGGGGATGGTAGTAGGAAATATATTTATCAACACTGTTAA

Upstream 100 bases:

>100_bases
TGCAATGTGCTTTATATGAGTTCAGGATTTATTGGAGTTAAATTGTAATAAAAAAGCTTATTTCTCAAGATCTGCATTTA
ATAAAGTTAAAAAAGAAAAT

Downstream 100 bases:

>100_bases
TGTTTTCGGTCGCAAGTAAAGCGTATATAAGATGAAGCAAATACATATGCCTATTGGTGTTATGGGTTGTTTGCCGAAAA
TGCCAGTAGATTACCCAATA

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: CS; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MCLLKDAIIHYSNKEYEKAKELFQIAGDRYGKNVVAANIYFCNKALNANHAVIADSFSKEKSYINSRLDPATILMLHQNG
DIVLDDDQKNECILLYNKLTERKSEDADVKKIDPIPADWPTDLILSPIPESTNDFYWYLGRKARKNNKYSQIGLSVIVPT
FNRSRILDITLACLVNQETEYPFEIVVADDGSKEAVIDIVKKYESIIDIKYIRQKDYGYQLCAVRNLGLRAAKYEFVAIL
DCDMAPNIKWVQSYMELLVENDDLALIGPRKYVDTNGLSASSFLDDKNLIELLPEVKTNNNVAGKDIESISVDWRLEHFN
HTQNLRLCDTPFRYFSGGNVAFSRKWLNKAGWFDEEFTQWGGEDNEFGYRLYRQGCFFQAVAGGIAYHQEPPGKENETDR
AAGKKVTVNLVHEKVPYFYRKYESDEKFKMYNVPLVSIYIPAYNCENYIVRCVESALNQTITDLEVCICNDGSTDNTLDV
LYDAFGNNPRVHIIDKKNGGIGSASNTAVRMARGFYVGQLDSDDYLEPDAVELCLKEFLSDRSLVCVYTTNRNIKPDGSI
IAKGYNWPHYSREKILTTMIIHHFRMFTIRSWNLTDGFDEQMSNAIDYDMFLKLSEVGKFKHINKICYNRLLHGENTSIK
NLSIQKKNHFLAVNNSLKRQGINCYTYIPKEDGDGSRKYIYQHC

Sequences:

>Translated_684_residues
MCLLKDAIIHYSNKEYEKAKELFQIAGDRYGKNVVAANIYFCNKALNANHAVIADSFSKEKSYINSRLDPATILMLHQNG
DIVLDDDQKNECILLYNKLTERKSEDADVKKIDPIPADWPTDLILSPIPESTNDFYWYLGRKARKNNKYSQIGLSVIVPT
FNRSRILDITLACLVNQETEYPFEIVVADDGSKEAVIDIVKKYESIIDIKYIRQKDYGYQLCAVRNLGLRAAKYEFVAIL
DCDMAPNIKWVQSYMELLVENDDLALIGPRKYVDTNGLSASSFLDDKNLIELLPEVKTNNNVAGKDIESISVDWRLEHFN
HTQNLRLCDTPFRYFSGGNVAFSRKWLNKAGWFDEEFTQWGGEDNEFGYRLYRQGCFFQAVAGGIAYHQEPPGKENETDR
AAGKKVTVNLVHEKVPYFYRKYESDEKFKMYNVPLVSIYIPAYNCENYIVRCVESALNQTITDLEVCICNDGSTDNTLDV
LYDAFGNNPRVHIIDKKNGGIGSASNTAVRMARGFYVGQLDSDDYLEPDAVELCLKEFLSDRSLVCVYTTNRNIKPDGSI
IAKGYNWPHYSREKILTTMIIHHFRMFTIRSWNLTDGFDEQMSNAIDYDMFLKLSEVGKFKHINKICYNRLLHGENTSIK
NLSIQKKNHFLAVNNSLKRQGINCYTYIPKEDGDGSRKYIYQHC
>Mature_684_residues
MCLLKDAIIHYSNKEYEKAKELFQIAGDRYGKNVVAANIYFCNKALNANHAVIADSFSKEKSYINSRLDPATILMLHQNG
DIVLDDDQKNECILLYNKLTERKSEDADVKKIDPIPADWPTDLILSPIPESTNDFYWYLGRKARKNNKYSQIGLSVIVPT
FNRSRILDITLACLVNQETEYPFEIVVADDGSKEAVIDIVKKYESIIDIKYIRQKDYGYQLCAVRNLGLRAAKYEFVAIL
DCDMAPNIKWVQSYMELLVENDDLALIGPRKYVDTNGLSASSFLDDKNLIELLPEVKTNNNVAGKDIESISVDWRLEHFN
HTQNLRLCDTPFRYFSGGNVAFSRKWLNKAGWFDEEFTQWGGEDNEFGYRLYRQGCFFQAVAGGIAYHQEPPGKENETDR
AAGKKVTVNLVHEKVPYFYRKYESDEKFKMYNVPLVSIYIPAYNCENYIVRCVESALNQTITDLEVCICNDGSTDNTLDV
LYDAFGNNPRVHIIDKKNGGIGSASNTAVRMARGFYVGQLDSDDYLEPDAVELCLKEFLSDRSLVCVYTTNRNIKPDGSI
IAKGYNWPHYSREKILTTMIIHHFRMFTIRSWNLTDGFDEQMSNAIDYDMFLKLSEVGKFKHINKICYNRLLHGENTSIK
NLSIQKKNHFLAVNNSLKRQGINCYTYIPKEDGDGSRKYIYQHC

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790044, Length=106, Percent_Identity=36.7924528301887, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788372, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 78546; Mature: 78546

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00527 RIBOSOMAL_S14

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLLKDAIIHYSNKEYEKAKELFQIAGDRYGKNVVAANIYFCNKALNANHAVIADSFSKE
CCEECCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEECCHHHH
KSYINSRLDPATILMLHQNGDIVLDDDQKNECILLYNKLTERKSEDADVKKIDPIPADWP
HHHHHCCCCCEEEEEEECCCCEEEECCCCCCEEEEEEHHHCCCCCCCCCEECCCCCCCCC
TDLILSPIPESTNDFYWYLGRKARKNNKYSQIGLSVIVPTFNRSRILDITLACLVNQETE
CCCEECCCCCCCCCEEEEECCHHHCCCCHHEECEEEEEECCCCCEEEEEEEEEEECCCCC
YPFEIVVADDGSKEAVIDIVKKYESIIDIKYIRQKDYGYQLCAVRNLGLRAAKYEFVAIL
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCEEECEEEEEEE
DCDMAPNIKWVQSYMELLVENDDLALIGPRKYVDTNGLSASSFLDDKNLIELLPEVKTNN
ECCCCCCHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCHHHHCCCCHHHHHCCCCCCCC
NVAGKDIESISVDWRLEHFNHTQNLRLCDTPFRYFSGGNVAFSRKWLNKAGWFDEEFTQW
CCCCCCCCEEEEEEEEEECCCCCCCEEECCCHHHCCCCCEEEEHHHHHHCCCCCHHHHHC
GGEDNEFGYRLYRQGCFFQAVAGGIAYHQEPPGKENETDRAAGKKVTVNLVHEKVPYFYR
CCCCCCHHHHHHHCCCHHHHHHCCCEECCCCCCCCCCCHHHCCCEEEEEEEHHHCCHHHH
KYESDEKFKMYNVPLVSIYIPAYNCENYIVRCVESALNQTITDLEVCICNDGSTDNTLDV
HCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHH
LYDAFGNNPRVHIIDKKNGGIGSASNTAVRMARGFYVGQLDSDDYLEPDAVELCLKEFLS
HHHHHCCCCEEEEEECCCCCCCCCCCHHHEEECCEEEEECCCCCCCCCHHHHHHHHHHHC
DRSLVCVYTTNRNIKPDGSIIAKGYNWPHYSREKILTTMIIHHFRMFTIRSWNLTDGFDE
CCCEEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCHHH
QMSNAIDYDMFLKLSEVGKFKHINKICYNRLLHGENTSIKNLSIQKKNHFLAVNNSLKRQ
HHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCHHHC
GINCYTYIPKEDGDGSRKYIYQHC
CCEEEEECCCCCCCCCCCEEEECC
>Mature Secondary Structure
MCLLKDAIIHYSNKEYEKAKELFQIAGDRYGKNVVAANIYFCNKALNANHAVIADSFSKE
CCEECCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEECCHHHH
KSYINSRLDPATILMLHQNGDIVLDDDQKNECILLYNKLTERKSEDADVKKIDPIPADWP
HHHHHCCCCCEEEEEEECCCCEEEECCCCCCEEEEEEHHHCCCCCCCCCEECCCCCCCCC
TDLILSPIPESTNDFYWYLGRKARKNNKYSQIGLSVIVPTFNRSRILDITLACLVNQETE
CCCEECCCCCCCCCEEEEECCHHHCCCCHHEECEEEEEECCCCCEEEEEEEEEEECCCCC
YPFEIVVADDGSKEAVIDIVKKYESIIDIKYIRQKDYGYQLCAVRNLGLRAAKYEFVAIL
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCEEECEEEEEEE
DCDMAPNIKWVQSYMELLVENDDLALIGPRKYVDTNGLSASSFLDDKNLIELLPEVKTNN
ECCCCCCHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCHHHHCCCCHHHHHCCCCCCCC
NVAGKDIESISVDWRLEHFNHTQNLRLCDTPFRYFSGGNVAFSRKWLNKAGWFDEEFTQW
CCCCCCCCEEEEEEEEEECCCCCCCEEECCCHHHCCCCCEEEEHHHHHHCCCCCHHHHHC
GGEDNEFGYRLYRQGCFFQAVAGGIAYHQEPPGKENETDRAAGKKVTVNLVHEKVPYFYR
CCCCCCHHHHHHHCCCHHHHHHCCCEECCCCCCCCCCCHHHCCCEEEEEEEHHHCCHHHH
KYESDEKFKMYNVPLVSIYIPAYNCENYIVRCVESALNQTITDLEVCICNDGSTDNTLDV
HCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHH
LYDAFGNNPRVHIIDKKNGGIGSASNTAVRMARGFYVGQLDSDDYLEPDAVELCLKEFLS
HHHHHCCCCEEEEEECCCCCCCCCCCHHHEEECCEEEEECCCCCCCCCHHHHHHHHHHHC
DRSLVCVYTTNRNIKPDGSIIAKGYNWPHYSREKILTTMIIHHFRMFTIRSWNLTDGFDE
CCCEEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCHHH
QMSNAIDYDMFLKLSEVGKFKHINKICYNRLLHGENTSIKNLSIQKKNHFLAVNNSLKRQ
HHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCHHHC
GINCYTYIPKEDGDGSRKYIYQHC
CCEEEEECCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10818104; 11230405; 11248100 [H]