Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 119358081

GI number: 119358081

Start: 2644105

End: 2646552

Strand: Direct

Name: cirA [H]

Synonym: Cpha266_2310

Alternate gene names: 119358081

Gene position: 2644105-2646552 (Clockwise)

Preceding gene: 119358078

Following gene: 119358082

Centisome position: 84.37

GC content: 54.49

Gene sequence:

>2448_bases
GTGTTTTTTACGCTAACCCTGGGTGATTCTTATTTTCCGAAATTGGCTTATTCTTGTTTTCCGATCACAGTAGTTGGCGC
ATCGGTAGTTATTGCCGGGACAACTCTCGGTACAGCTACCGACATGAACGGCAACTTCGTGCTCAAAGGAGTCCCGGCAA
AACAACAGCGAGTCTCCGTCTCGATTGTCGGTTACGCACCTTCAAGCCAGGTTGTCACCGTCGGCGCAGGTCAAACCGCA
GTAGCGAACTTCTCGCTCGGCCAAACCACCGTTATGGCATCGGAAGTAGTTGTCGGCGCGGCGCTTTACAAGCAGGACAG
GCTTGAAGTTCCGGTGACTGCCAACGTGGTTTCTGCCGAAAAAATCAAACAGGAACCTAACCCGACCCTCGATCAGGTCG
TTGAGGACGTCCCTGGCGTTGTTGTCACCCGCGCCGGAGGACAAACAACCTCAACCCTGCAGATCCGCGGCTCCAATACT
TATCAGGGCGGTGCAATCGGCACCCGAGTGCAGGGTTTCTATGATGGATTCCCGCTCAACAGCCCTGAAACCGGTGAAGT
TGTCTGGTCTTCGGTCAACATGAACGCAGCCGACAAGGTCGAGGTGCTCAAAGGTTCAGCAGCAACCCTCTACGGTTCGG
GCGCCATGGGCGGTGTGGTTAACGTGTTCGGCCACCTTCCGGAAACCCTTGAAGTGAAAGCCGGAACAAGCGCAGGCTTT
TACGATGCGCCTCCTTCCAGCGACAAGAGCGTTTACCGCGACGGTTACACCCCGTGGTTCTGGAACAGCTACGTAGGCAT
CGGCAACAAGAGCGGCAAGCTCAGCTACAGCCTCCTCTACTCGCACAGCGAGGACGACGGCTACCGCCAGAATGCACAGA
CCCTTCTGAACGACGTCAAGCTGAAAGCGCGCTACGACATCGATGCGAAACAGTACTTGCAGCTCAGCGCCTTTTATAAC
GAAACGGAGGGCGGCTACGCATACACATTACCTTATGACGCGACAGTTGCAACCGGAACATTCATCCCTCACCCTGAACT
TGCCTACGATGTTTATGTGAACGCCCGATTCCCCGCAGCAGGGCCATACACGAAATACGATGTCTATACTGACGATCTCA
TTAAGCGGAATAACGCACTGGCGGGCCTGAACTACGTAAACCTGCTGAGCGACAACCTCACCCTTGACGCCCGGCTCTAC
TACACCCGCAACGCAACCACTTACGAGTATAACAATACGCCGGCAAACCAGATGTATGCAACCGGCGCCACCCGCTATCC
GGGTGAATTCAATGAAACCAGCTCGAACCGGTACGGAGCAGGCGTAAAACTTGACTGGCGAGTAAGCGACAGCCATCGCC
TTCTTTTCGGTCTTGACGGCAACATTATTGACGTTCAGTCAACGCAGTATACAGGGGAAATTCCCTCGGCACACCCTTTA
AGCAATAGTGACCTCAACGATATCCAGGAAAAAAACTTTGCCGCATTCGTGCAGGACGAGTGGAAACTCACCGACAAGCT
GACTGCCCTGCTCTCCCTGCGGTATGACTGGAGCGGTATCGATGCTGATGAGGTTACGTATGTTGACTACAGAAGGCCTG
TTTATGTTACTATCCCTGGGGCGGGAACTGTCGCAACATATCCGTTTACGAAAACTGAATCAATTGAAAACCCGTCGGTC
GATGCCATCAGCCCTCGTATCGCGCTCAACTACAAGGCCACGGACGACATGAGCTTCCGCGCATCGTGGGGAACAAGCTT
CCGCGCGCCGACGCTTGCGGAACGGTTTGTCCGAGATGCCGGAATCCTTAAAGGCGTACCTAACCCGGCGCTCGACAAGG
AGACCATGACCGCCTACGAGATCGGCGTCTACAAGCAGTTTGGCGACAAGGTCTCGCTCGACGTGGCCGCATTCATCAAC
GATTACGACAACCTGATCGAATCAGTCAAGCTGCAGGGGACAACATTCGAATTCCAGAACATCACGAAGGCCCGTATCTG
GGGCATCGAGACAAGCCTGAACATTCGTCCGAATCCTTCGTGGAACGTCAATCTGGCTTACACCTACATGAACGCCAAAA
ACACCGACTACAAGCCAAGCACCCCTGCGGTTGCCATTGACTCCAATCCCGATCCGGAATGGCTGCCCATGCGGCCGGAA
CATACCGCCTCGGCAAGCGTGGCCTGGAAAGCCAACGACAACCTGACGCTGAACCTGAACGGACGGTACGTCGGCGAATA
CAAGGCCGTGAATCTCTATACCAATACCGAAGGCTACAACTACCCCGGCGACTTCGTGGTGTTCAACCTCGGCATGAAGT
ACAAAATCACCGACAACATCGGCGCAACACTGCTCTGCAACAACATCGGCAATGTGCAGTACGAAGAGGCCGAATGGTTC
CGCGCTCCGGGCAGAAGCTTCGTGCTTGGTGTTGACCTGACCTACTGA

Upstream 100 bases:

>100_bases
GCAAATTCCTTAACTTTGTTGTACATGGTTAGCTTTTTTAACTGTGTCCTCATAGCTCTGGGGTTTGATTTGGTTGGCAC
CTTCAAACTACGAGCTATGG

Downstream 100 bases:

>100_bases
ACCACAAACAAAAAGCTGAAAAGCCCGGTTCATTTGCAGGCCCCTTTCAGAGGGGCCTGCTCTTTTTATAGTTAGCATTC
ATCGAATGATTTTATTACAT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MFFTLTLGDSYFPKLAYSCFPITVVGASVVIAGTTLGTATDMNGNFVLKGVPAKQQRVSVSIVGYAPSSQVVTVGAGQTA
VANFSLGQTTVMASEVVVGAALYKQDRLEVPVTANVVSAEKIKQEPNPTLDQVVEDVPGVVVTRAGGQTTSTLQIRGSNT
YQGGAIGTRVQGFYDGFPLNSPETGEVVWSSVNMNAADKVEVLKGSAATLYGSGAMGGVVNVFGHLPETLEVKAGTSAGF
YDAPPSSDKSVYRDGYTPWFWNSYVGIGNKSGKLSYSLLYSHSEDDGYRQNAQTLLNDVKLKARYDIDAKQYLQLSAFYN
ETEGGYAYTLPYDATVATGTFIPHPELAYDVYVNARFPAAGPYTKYDVYTDDLIKRNNALAGLNYVNLLSDNLTLDARLY
YTRNATTYEYNNTPANQMYATGATRYPGEFNETSSNRYGAGVKLDWRVSDSHRLLFGLDGNIIDVQSTQYTGEIPSAHPL
SNSDLNDIQEKNFAAFVQDEWKLTDKLTALLSLRYDWSGIDADEVTYVDYRRPVYVTIPGAGTVATYPFTKTESIENPSV
DAISPRIALNYKATDDMSFRASWGTSFRAPTLAERFVRDAGILKGVPNPALDKETMTAYEIGVYKQFGDKVSLDVAAFIN
DYDNLIESVKLQGTTFEFQNITKARIWGIETSLNIRPNPSWNVNLAYTYMNAKNTDYKPSTPAVAIDSNPDPEWLPMRPE
HTASASVAWKANDNLTLNLNGRYVGEYKAVNLYTNTEGYNYPGDFVVFNLGMKYKITDNIGATLLCNNIGNVQYEEAEWF
RAPGRSFVLGVDLTY

Sequences:

>Translated_815_residues
MFFTLTLGDSYFPKLAYSCFPITVVGASVVIAGTTLGTATDMNGNFVLKGVPAKQQRVSVSIVGYAPSSQVVTVGAGQTA
VANFSLGQTTVMASEVVVGAALYKQDRLEVPVTANVVSAEKIKQEPNPTLDQVVEDVPGVVVTRAGGQTTSTLQIRGSNT
YQGGAIGTRVQGFYDGFPLNSPETGEVVWSSVNMNAADKVEVLKGSAATLYGSGAMGGVVNVFGHLPETLEVKAGTSAGF
YDAPPSSDKSVYRDGYTPWFWNSYVGIGNKSGKLSYSLLYSHSEDDGYRQNAQTLLNDVKLKARYDIDAKQYLQLSAFYN
ETEGGYAYTLPYDATVATGTFIPHPELAYDVYVNARFPAAGPYTKYDVYTDDLIKRNNALAGLNYVNLLSDNLTLDARLY
YTRNATTYEYNNTPANQMYATGATRYPGEFNETSSNRYGAGVKLDWRVSDSHRLLFGLDGNIIDVQSTQYTGEIPSAHPL
SNSDLNDIQEKNFAAFVQDEWKLTDKLTALLSLRYDWSGIDADEVTYVDYRRPVYVTIPGAGTVATYPFTKTESIENPSV
DAISPRIALNYKATDDMSFRASWGTSFRAPTLAERFVRDAGILKGVPNPALDKETMTAYEIGVYKQFGDKVSLDVAAFIN
DYDNLIESVKLQGTTFEFQNITKARIWGIETSLNIRPNPSWNVNLAYTYMNAKNTDYKPSTPAVAIDSNPDPEWLPMRPE
HTASASVAWKANDNLTLNLNGRYVGEYKAVNLYTNTEGYNYPGDFVVFNLGMKYKITDNIGATLLCNNIGNVQYEEAEWF
RAPGRSFVLGVDLTY
>Mature_815_residues
MFFTLTLGDSYFPKLAYSCFPITVVGASVVIAGTTLGTATDMNGNFVLKGVPAKQQRVSVSIVGYAPSSQVVTVGAGQTA
VANFSLGQTTVMASEVVVGAALYKQDRLEVPVTANVVSAEKIKQEPNPTLDQVVEDVPGVVVTRAGGQTTSTLQIRGSNT
YQGGAIGTRVQGFYDGFPLNSPETGEVVWSSVNMNAADKVEVLKGSAATLYGSGAMGGVVNVFGHLPETLEVKAGTSAGF
YDAPPSSDKSVYRDGYTPWFWNSYVGIGNKSGKLSYSLLYSHSEDDGYRQNAQTLLNDVKLKARYDIDAKQYLQLSAFYN
ETEGGYAYTLPYDATVATGTFIPHPELAYDVYVNARFPAAGPYTKYDVYTDDLIKRNNALAGLNYVNLLSDNLTLDARLY
YTRNATTYEYNNTPANQMYATGATRYPGEFNETSSNRYGAGVKLDWRVSDSHRLLFGLDGNIIDVQSTQYTGEIPSAHPL
SNSDLNDIQEKNFAAFVQDEWKLTDKLTALLSLRYDWSGIDADEVTYVDYRRPVYVTIPGAGTVATYPFTKTESIENPSV
DAISPRIALNYKATDDMSFRASWGTSFRAPTLAERFVRDAGILKGVPNPALDKETMTAYEIGVYKQFGDKVSLDVAAFIN
DYDNLIESVKLQGTTFEFQNITKARIWGIETSLNIRPNPSWNVNLAYTYMNAKNTDYKPSTPAVAIDSNPDPEWLPMRPE
HTASASVAWKANDNLTLNLNGRYVGEYKAVNLYTNTEGYNYPGDFVVFNLGMKYKITDNIGATLLCNNIGNVQYEEAEWF
RAPGRSFVLGVDLTY

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=357, Percent_Identity=23.5294117647059, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 89423; Mature: 89423

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFTLTLGDSYFPKLAYSCFPITVVGASVVIAGTTLGTATDMNGNFVLKGVPAKQQRVSV
CEEEEEECCCCCHHHHHCCCEEEEECCEEEEEECCCCCEECCCCCEEEECCCCCCCEEEE
SIVGYAPSSQVVTVGAGQTAVANFSLGQTTVMASEVVVGAALYKQDRLEVPVTANVVSAE
EEEEECCCCCEEEEECCCEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCEEECEECHH
KIKQEPNPTLDQVVEDVPGVVVTRAGGQTTSTLQIRGSNTYQGGAIGTRVQGFYDGFPLN
HHHCCCCCCHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCCCCCCEECEEECCCCCC
SPETGEVVWSSVNMNAADKVEVLKGSAATLYGSGAMGGVVNVFGHLPETLEVKAGTSAGF
CCCCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCC
YDAPPSSDKSVYRDGYTPWFWNSYVGIGNKSGKLSYSLLYSHSEDDGYRQNAQTLLNDVK
CCCCCCCCCCHHCCCCCCCEECCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHEE
LKARYDIDAKQYLQLSAFYNETEGGYAYTLPYDATVATGTFIPHPELAYDVYVNARFPAA
EEEEECCCHHHHEEEEEEECCCCCCEEEECCCCCEEECCCCCCCCCEEEEEEEEEECCCC
GPYTKYDVYTDDLIKRNNALAGLNYVNLLSDNLTLDARLYYTRNATTYEYNNTPANQMYA
CCCEEEEEECHHHHHCCCCEECCCEEEEECCCEEEEEEEEEECCCEEEEECCCCCHHEEE
TGATRYPGEFNETSSNRYGAGVKLDWRVSDSHRLLFGLDGNIIDVQSTQYTGEIPSAHPL
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEECCEECCCCCCCCCC
SNSDLNDIQEKNFAAFVQDEWKLTDKLTALLSLRYDWSGIDADEVTYVDYRRPVYVTIPG
CCCCHHHHHHCCEEEEEECCHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCCEEEEECC
AGTVATYPFTKTESIENPSVDAISPRIALNYKATDDMSFRASWGTSFRAPTLAERFVRDA
CCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHH
GILKGVPNPALDKETMTAYEIGVYKQFGDKVSLDVAAFINDYDNLIESVKLQGTTFEFQN
HHHCCCCCCCCCCCCEEEEEEEEEHHCCCEEEEEHHHHHHHHHHHHHHEEECCCEEECCC
ITKARIWGIETSLNIRPNPSWNVNLAYTYMNAKNTDYKPSTPAVAIDSNPDPEWLPMRPE
CCEEEEEEEEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCC
HTASASVAWKANDNLTLNLNGRYVGEYKAVNLYTNTEGYNYPGDFVVFNLGMKYKITDNI
CCCCEEEEEECCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCCEEEEECCEEEEEECCC
GATLLCNNIGNVQYEEAEWFRAPGRSFVLGVDLTY
CEEEEECCCCCCEECCHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MFFTLTLGDSYFPKLAYSCFPITVVGASVVIAGTTLGTATDMNGNFVLKGVPAKQQRVSV
CEEEEEECCCCCHHHHHCCCEEEEECCEEEEEECCCCCEECCCCCEEEECCCCCCCEEEE
SIVGYAPSSQVVTVGAGQTAVANFSLGQTTVMASEVVVGAALYKQDRLEVPVTANVVSAE
EEEEECCCCCEEEEECCCEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCEEECEECHH
KIKQEPNPTLDQVVEDVPGVVVTRAGGQTTSTLQIRGSNTYQGGAIGTRVQGFYDGFPLN
HHHCCCCCCHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCCCCCCEECEEECCCCCC
SPETGEVVWSSVNMNAADKVEVLKGSAATLYGSGAMGGVVNVFGHLPETLEVKAGTSAGF
CCCCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCC
YDAPPSSDKSVYRDGYTPWFWNSYVGIGNKSGKLSYSLLYSHSEDDGYRQNAQTLLNDVK
CCCCCCCCCCHHCCCCCCCEECCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHEE
LKARYDIDAKQYLQLSAFYNETEGGYAYTLPYDATVATGTFIPHPELAYDVYVNARFPAA
EEEEECCCHHHHEEEEEEECCCCCCEEEECCCCCEEECCCCCCCCCEEEEEEEEEECCCC
GPYTKYDVYTDDLIKRNNALAGLNYVNLLSDNLTLDARLYYTRNATTYEYNNTPANQMYA
CCCEEEEEECHHHHHCCCCEECCCEEEEECCCEEEEEEEEEECCCEEEEECCCCCHHEEE
TGATRYPGEFNETSSNRYGAGVKLDWRVSDSHRLLFGLDGNIIDVQSTQYTGEIPSAHPL
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEECCEECCCCCCCCCC
SNSDLNDIQEKNFAAFVQDEWKLTDKLTALLSLRYDWSGIDADEVTYVDYRRPVYVTIPG
CCCCHHHHHHCCEEEEEECCHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCCEEEEECC
AGTVATYPFTKTESIENPSVDAISPRIALNYKATDDMSFRASWGTSFRAPTLAERFVRDA
CCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHH
GILKGVPNPALDKETMTAYEIGVYKQFGDKVSLDVAAFINDYDNLIESVKLQGTTFEFQN
HHHCCCCCCCCCCCCEEEEEEEEEHHCCCEEEEEHHHHHHHHHHHHHHEEECCCEEECCC
ITKARIWGIETSLNIRPNPSWNVNLAYTYMNAKNTDYKPSTPAVAIDSNPDPEWLPMRPE
CCEEEEEEEEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCC
HTASASVAWKANDNLTLNLNGRYVGEYKAVNLYTNTEGYNYPGDFVVFNLGMKYKITDNI
CCCCEEEEEECCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCCEEEEECCEEEEEECCC
GATLLCNNIGNVQYEEAEWFRAPGRSFVLGVDLTY
CEEEEECCCCCCEECCHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]