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The map label for this gene is lhr [C]

Identifier: 119358005

GI number: 119358005

Start: 2552272

End: 2554404

Strand: Reverse

Name: lhr [C]

Synonym: Cpha266_2227

Alternate gene names: 119358005

Gene position: 2554404-2552272 (Counterclockwise)

Preceding gene: 119358006

Following gene: 119358004

Centisome position: 81.51

GC content: 31.93

Gene sequence:

>2133_bases
ATGTCATTTGATTTACTTTCAGAACCAATACGAAAATTCATTCGTGATAAGGGTTGGGAGCAGTTGCGACCAATTCAAAC
AGCAGCTATTGCCAAAATTTTAGCATCAGACGACAATTTTATTTTGGCATCACGGACGGCATCGGGAAAAACAGAAGCTG
CATTTTTGCCAATTCTTTCAAAAGTTGATTTCAATGATTCAGGTGTTCAAGTTCTTTACATTTCACCGTTAATAGCTTTA
ATTAATGACCAATTTTATCGTATTGAAGAACTTTGCAAAAATCTTGATGTAACAGTAACCAAATGGCACGGAGAAGCAAA
TAAAACTTTGAAAGATAGGCTAATCAAACAACCAACAGGAATTGTTTTGATTACACCCGAATCATTGGAAGCAATGTTCG
TAAACAAACCTTTTAATGTTAAAAAGCTGTTTTCAAATTTAAAGTATGTTGTAATAGATGAAGTACATTCTTTCATTGGA
ACAGACAGAGGAACTCAATTAAAATCTATTTTAAGCAGACTTCAAAGGGTAAATTCCCAATCATTCAGCATTGTAGGACT
TTCAGCAACAATTGGAGATTACAATGAAGCAAAAAAATTTATCGGTAATGAAAAAAACACCAAAGTGTTGCTTGATAGAA
CAGCCAAAGAAATCAATTCTGTTTTCCGATTTTTCAAAAAAGAAAAAGAAGAATTGCCTTTGGAACTTTTGAAAGACTTG
TATATAGAAACCAAAGATAATAAAGTTTTAATATTCCCAAACAGCCGTGGACGAGCAGAAGAAGTAGCGGTAAAACTTAA
AAAAATATCAGAAAGAGTAAAAGGACATCCACATTACTTTTCACATCACTCGTCAGTGGACAGAGAAGTAAGGGAGTATG
TTGAATACTTTGCAAAGAACAACAAGCGACATAACTTTTGTATTTCTTGTACATCAACATTGGAACTTGGTATTGACATT
GGTTCGGTTGACGAAGTTGTTCAAATAGATGCAACACATAGTATTGCTTCATTAATCCAAAGGGTTGGAAGAAGTGGTAG
AAAAGATGGGGAAAGCAGTAATTTATTTCTTTATGCAACTACTCAATGGAGTTTACTACAATCTATTGCTTGTTGGCTTT
TATACAATGAAAGTTTTATCGAGCCACCCGAAAAAAATGAAAAGCCTTATGATATATTAGTTCATCAAGCATTGTCGATA
ACAAAAAGTCATTCAGGAATTCTATTAACAGAACTTATAAAACAACTAAAAGAAAATTCAGCTTTCAATTCAATTGAGCA
ATCAGAAGTTGAAGAAATACTTCAAAATTTAATTGAAATTGATTTCCTTGAAAAACTACAGCGCGAGGTTATAGTTGGTG
TTCAAGGAGAGAAAGTTGTTAATAGTAGAGAGTTTTATAGCGTTTTCAAAACCGAAGAAAATTTTAAAGTTGTAAATGCA
GGTAATACAATCGGAGAAATTCCATTTTCACCTCAAATTATAGAAGATGAAAACATATTACTATCTGCCAAAATCTGGAA
GATAACGTTCGTTGACCATAAAGCAAAAAAAATAGAAGTTATTCCTGCGAAAGACGGAAAAAAGCCAATATTTTTTGGTG
GTGGTGCTATTCTTCATCAAAAAATAAGAGAGAAAATGTTTGAGATTTTGTATTCTAAAACAGAATACGATTTTCTTGAC
GAACCGAGTTTTGAAGAAATAGAAATGATGCGTAAAGATTTTTCTGTTTTCAATATCAAGGATCTGCAATCTGAAAGACC
ATTATTGACAGCAGAAAAACATTTGCAACTATTCACATTTACAGGAACAAGAATAAATAGGACGTTACAATTGCTTTTGA
ATATTGCTGGAATTAAAAACACGCTTGACGACAGTAACAGCTCGTTTAATATTGAAGTTCCAAAAGAGGATATGATATCT
AAATGGAATTATGTATCCTTTCCTTTAACAGACATTGATACTCATATTTCAACACTTTTAGAGACTAACCCGACACTTTT
AGATTTCTCTAAATGGGGAAACTATTTGCCAAAAATATATCAAGTTAAACTTGTAAAGAATAAATATTTTGATATTGAGC
AGACAAAGGAACTATTAAATAAATTAAAATTAATCAATAACAAACAGACTTGA

Upstream 100 bases:

>100_bases
GACAAAATCCAGCAGTAGATAAAAACAAACTATTTGGTGAACTTGAAATTTCGGATGAAAGACCTAATGAAGTTTCTTTA
GACAGCATTGAAGAATTATA

Downstream 100 bases:

>100_bases
GATAGTTATTAGTTGAATGGCCAACGTATTTGGCTGCACATTTGCGAAACCGTTCAAACCAACCCAAAAGCCAAGTTTTG
TAAAAGAGCCTCCAATCCAA

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MSFDLLSEPIRKFIRDKGWEQLRPIQTAAIAKILASDDNFILASRTASGKTEAAFLPILSKVDFNDSGVQVLYISPLIAL
INDQFYRIEELCKNLDVTVTKWHGEANKTLKDRLIKQPTGIVLITPESLEAMFVNKPFNVKKLFSNLKYVVIDEVHSFIG
TDRGTQLKSILSRLQRVNSQSFSIVGLSATIGDYNEAKKFIGNEKNTKVLLDRTAKEINSVFRFFKKEKEELPLELLKDL
YIETKDNKVLIFPNSRGRAEEVAVKLKKISERVKGHPHYFSHHSSVDREVREYVEYFAKNNKRHNFCISCTSTLELGIDI
GSVDEVVQIDATHSIASLIQRVGRSGRKDGESSNLFLYATTQWSLLQSIACWLLYNESFIEPPEKNEKPYDILVHQALSI
TKSHSGILLTELIKQLKENSAFNSIEQSEVEEILQNLIEIDFLEKLQREVIVGVQGEKVVNSREFYSVFKTEENFKVVNA
GNTIGEIPFSPQIIEDENILLSAKIWKITFVDHKAKKIEVIPAKDGKKPIFFGGGAILHQKIREKMFEILYSKTEYDFLD
EPSFEEIEMMRKDFSVFNIKDLQSERPLLTAEKHLQLFTFTGTRINRTLQLLLNIAGIKNTLDDSNSSFNIEVPKEDMIS
KWNYVSFPLTDIDTHISTLLETNPTLLDFSKWGNYLPKIYQVKLVKNKYFDIEQTKELLNKLKLINNKQT

Sequences:

>Translated_710_residues
MSFDLLSEPIRKFIRDKGWEQLRPIQTAAIAKILASDDNFILASRTASGKTEAAFLPILSKVDFNDSGVQVLYISPLIAL
INDQFYRIEELCKNLDVTVTKWHGEANKTLKDRLIKQPTGIVLITPESLEAMFVNKPFNVKKLFSNLKYVVIDEVHSFIG
TDRGTQLKSILSRLQRVNSQSFSIVGLSATIGDYNEAKKFIGNEKNTKVLLDRTAKEINSVFRFFKKEKEELPLELLKDL
YIETKDNKVLIFPNSRGRAEEVAVKLKKISERVKGHPHYFSHHSSVDREVREYVEYFAKNNKRHNFCISCTSTLELGIDI
GSVDEVVQIDATHSIASLIQRVGRSGRKDGESSNLFLYATTQWSLLQSIACWLLYNESFIEPPEKNEKPYDILVHQALSI
TKSHSGILLTELIKQLKENSAFNSIEQSEVEEILQNLIEIDFLEKLQREVIVGVQGEKVVNSREFYSVFKTEENFKVVNA
GNTIGEIPFSPQIIEDENILLSAKIWKITFVDHKAKKIEVIPAKDGKKPIFFGGGAILHQKIREKMFEILYSKTEYDFLD
EPSFEEIEMMRKDFSVFNIKDLQSERPLLTAEKHLQLFTFTGTRINRTLQLLLNIAGIKNTLDDSNSSFNIEVPKEDMIS
KWNYVSFPLTDIDTHISTLLETNPTLLDFSKWGNYLPKIYQVKLVKNKYFDIEQTKELLNKLKLINNKQT
>Mature_709_residues
SFDLLSEPIRKFIRDKGWEQLRPIQTAAIAKILASDDNFILASRTASGKTEAAFLPILSKVDFNDSGVQVLYISPLIALI
NDQFYRIEELCKNLDVTVTKWHGEANKTLKDRLIKQPTGIVLITPESLEAMFVNKPFNVKKLFSNLKYVVIDEVHSFIGT
DRGTQLKSILSRLQRVNSQSFSIVGLSATIGDYNEAKKFIGNEKNTKVLLDRTAKEINSVFRFFKKEKEELPLELLKDLY
IETKDNKVLIFPNSRGRAEEVAVKLKKISERVKGHPHYFSHHSSVDREVREYVEYFAKNNKRHNFCISCTSTLELGIDIG
SVDEVVQIDATHSIASLIQRVGRSGRKDGESSNLFLYATTQWSLLQSIACWLLYNESFIEPPEKNEKPYDILVHQALSIT
KSHSGILLTELIKQLKENSAFNSIEQSEVEEILQNLIEIDFLEKLQREVIVGVQGEKVVNSREFYSVFKTEENFKVVNAG
NTIGEIPFSPQIIEDENILLSAKIWKITFVDHKAKKIEVIPAKDGKKPIFFGGGAILHQKIREKMFEILYSKTEYDFLDE
PSFEEIEMMRKDFSVFNIKDLQSERPLLTAEKHLQLFTFTGTRINRTLQLLLNIAGIKNTLDDSNSSFNIEVPKEDMISK
WNYVSFPLTDIDTHISTLLETNPTLLDFSKWGNYLPKIYQVKLVKNKYFDIEQTKELLNKLKLINNKQT

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI169218225, Length=184, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI40217847, Length=184, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI262118318, Length=365, Percent_Identity=23.8356164383562, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI262231852, Length=365, Percent_Identity=23.8356164383562, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI216548263, Length=365, Percent_Identity=23.8356164383562, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI13518015, Length=365, Percent_Identity=23.8356164383562, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1787942, Length=623, Percent_Identity=23.4349919743178, Blast_Score=142, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17552114, Length=354, Percent_Identity=25.7062146892655, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532546, Length=358, Percent_Identity=24.5810055865922, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115532548, Length=358, Percent_Identity=24.5810055865922, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71987993, Length=356, Percent_Identity=27.5280898876405, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71987997, Length=356, Percent_Identity=27.5280898876405, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71987143, Length=353, Percent_Identity=24.6458923512748, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17537127, Length=392, Percent_Identity=22.9591836734694, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320041, Length=339, Percent_Identity=25.3687315634218, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321020, Length=387, Percent_Identity=22.4806201550388, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320224, Length=354, Percent_Identity=25.9887005649718, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321710, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI9755332, Length=380, Percent_Identity=24.7368421052632, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24583281, Length=354, Percent_Identity=25.9887005649718, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583279, Length=354, Percent_Identity=25.9887005649718, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28574898, Length=392, Percent_Identity=21.6836734693878, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647182, Length=399, Percent_Identity=23.0576441102757, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 81473; Mature: 81341

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDLLSEPIRKFIRDKGWEQLRPIQTAAIAKILASDDNFILASRTASGKTEAAFLPILS
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
KVDFNDSGVQVLYISPLIALINDQFYRIEELCKNLDVTVTKWHGEANKTLKDRLIKQPTG
HCCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCC
IVLITPESLEAMFVNKPFNVKKLFSNLKYVVIDEVHSFIGTDRGTQLKSILSRLQRVNSQ
EEEECCCCCCEEEECCCCCHHHHHHCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
SFSIVGLSATIGDYNEAKKFIGNEKNTKVLLDRTAKEINSVFRFFKKEKEELPLELLKDL
CEEEEEEEEECCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YIETKDNKVLIFPNSRGRAEEVAVKLKKISERVKGHPHYFSHHSSVDREVREYVEYFAKN
HEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHC
NKRHNFCISCTSTLELGIDIGSVDEVVQIDATHSIASLIQRVGRSGRKDGESSNLFLYAT
CCCCEEEEEECCEEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TQWSLLQSIACWLLYNESFIEPPEKNEKPYDILVHQALSITKSHSGILLTELIKQLKENS
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
AFNSIEQSEVEEILQNLIEIDFLEKLQREVIVGVQGEKVVNSREFYSVFKTEENFKVVNA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHCCHHHHHHHCCCCCEEEEEC
GNTIGEIPFSPQIIEDENILLSAKIWKITFVDHKAKKIEVIPAKDGKKPIFFGGGAILHQ
CCCCCCCCCCCEEECCCCEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEECCHHHHHH
KIREKMFEILYSKTEYDFLDEPSFEEIEMMRKDFSVFNIKDLQSERPLLTAEKHLQLFTF
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHCCCCCCEECCCCEEEEEE
TGTRINRTLQLLLNIAGIKNTLDDSNSSFNIEVPKEDMISKWNYVSFPLTDIDTHISTLL
ECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHCCCCEEECCHHHHHHHHHHHH
ETNPTLLDFSKWGNYLPKIYQVKLVKNKYFDIEQTKELLNKLKLINNKQT
HCCCCEEEHHHHCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFDLLSEPIRKFIRDKGWEQLRPIQTAAIAKILASDDNFILASRTASGKTEAAFLPILS
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
KVDFNDSGVQVLYISPLIALINDQFYRIEELCKNLDVTVTKWHGEANKTLKDRLIKQPTG
HCCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCC
IVLITPESLEAMFVNKPFNVKKLFSNLKYVVIDEVHSFIGTDRGTQLKSILSRLQRVNSQ
EEEECCCCCCEEEECCCCCHHHHHHCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
SFSIVGLSATIGDYNEAKKFIGNEKNTKVLLDRTAKEINSVFRFFKKEKEELPLELLKDL
CEEEEEEEEECCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YIETKDNKVLIFPNSRGRAEEVAVKLKKISERVKGHPHYFSHHSSVDREVREYVEYFAKN
HEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHC
NKRHNFCISCTSTLELGIDIGSVDEVVQIDATHSIASLIQRVGRSGRKDGESSNLFLYAT
CCCCEEEEEECCEEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TQWSLLQSIACWLLYNESFIEPPEKNEKPYDILVHQALSITKSHSGILLTELIKQLKENS
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
AFNSIEQSEVEEILQNLIEIDFLEKLQREVIVGVQGEKVVNSREFYSVFKTEENFKVVNA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHCCHHHHHHHCCCCCEEEEEC
GNTIGEIPFSPQIIEDENILLSAKIWKITFVDHKAKKIEVIPAKDGKKPIFFGGGAILHQ
CCCCCCCCCCCEEECCCCEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEECCHHHHHH
KIREKMFEILYSKTEYDFLDEPSFEEIEMMRKDFSVFNIKDLQSERPLLTAEKHLQLFTF
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHCCCCCCEECCCCEEEEEE
TGTRINRTLQLLLNIAGIKNTLDDSNSSFNIEVPKEDMISKWNYVSFPLTDIDTHISTLL
ECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHCCCCEEECCHHHHHHHHHHHH
ETNPTLLDFSKWGNYLPKIYQVKLVKNKYFDIEQTKELLNKLKLINNKQT
HCCCCEEEHHHHCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]