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The map label for this gene is asrB [H]

Identifier: 119357952

GI number: 119357952

Start: 2509247

End: 2510071

Strand: Direct

Name: asrB [H]

Synonym: Cpha266_2167

Alternate gene names: 119357952

Gene position: 2509247-2510071 (Clockwise)

Preceding gene: 119357951

Following gene: 119357953

Centisome position: 80.07

GC content: 54.06

Gene sequence:

>825_bases
ATGAAAACCGATATGGGGTACAAGTGCCGCATCACCAACGTCGTCAGCCTGACGGAACAGGAAAAACTCTTTCAGCTCCA
CATCGTCGATCCGCAGGAACGCAGAATTTTCCGGTTCAAACCCGGCCAGTTCATCATGCTCGAACTTCCGGGATACGGCG
ACGTGCCAATCTCCATATCGAGTTCATACAGCAATCATGAGTTCATCGAGCTCTGCATCCGCAAAGCCGGACATGTGACC
TCGGCACTCTTCAGAACCGAACCCGGTATGCATGTAGCTATCCGGGGCCCTTTCGGGTCATCGTTTCCAATGGATGAGAT
AGCCGGCCACCATGTACTGCTCGTTGCAGGAGGGCTCGGCATTGCGCCGCTTCGTGCGCCGCTCTTCTGGATAAACGAGC
ATCGCGACCGGTTCCGGGACGTACACCTGCTCTATGGCGCGAGAGAACCCTCGCAGCTCCTTTTTTCCTACCAGTTCGAC
GAGTGGAACACCATCAGCCATGTCCGGTTGCATACGATCGTCGAACATTCGGATGAGACATGGAAAGGCCGTACCGGCAT
GATCACTGAACTGTTCCGTGACATCGAAATCGATACGAAAAACACCTACGCTATCGTTTGCGGACCTCCGATCATGTTCA
AGTTCGTCTGCAGCTACCTCGACCGACTCGGAATACCTATGAACCGGATGTTCGTTTCGCTTGAACGGCGGATGCACTGC
GGCATGGGCAAATGCTGCAGGTGCATGGTAGGCTCCACCTTCACCTGCATCGACGGCCCGGTTTTCGATTACTGGTCGGT
CATGAATCTCAAGGAAGCCATTTAA

Upstream 100 bases:

>100_bases
AAGAATCATGCATGATTTGCGCTTCGCAATCCCCAGGCAAAACCTGAACCGGGAAGCGTTCGTATCGTCGGTGCCGGAGT
TCAACAGGAAATCGGACCTT

Downstream 100 bases:

>100_bases
CGAGGTCGGTATGAACCAACAGGGCATGCATTTCGAAAAACTGAAATTCGCCTCATTCGAATTCACCTGCTGCGAAGGTT
GCCAGTTACAGCTCGCCAAC

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NAD(P); FMNH2; 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKTDMGYKCRITNVVSLTEQEKLFQLHIVDPQERRIFRFKPGQFIMLELPGYGDVPISISSSYSNHEFIELCIRKAGHVT
SALFRTEPGMHVAIRGPFGSSFPMDEIAGHHVLLVAGGLGIAPLRAPLFWINEHRDRFRDVHLLYGAREPSQLLFSYQFD
EWNTISHVRLHTIVEHSDETWKGRTGMITELFRDIEIDTKNTYAIVCGPPIMFKFVCSYLDRLGIPMNRMFVSLERRMHC
GMGKCCRCMVGSTFTCIDGPVFDYWSVMNLKEAI

Sequences:

>Translated_274_residues
MKTDMGYKCRITNVVSLTEQEKLFQLHIVDPQERRIFRFKPGQFIMLELPGYGDVPISISSSYSNHEFIELCIRKAGHVT
SALFRTEPGMHVAIRGPFGSSFPMDEIAGHHVLLVAGGLGIAPLRAPLFWINEHRDRFRDVHLLYGAREPSQLLFSYQFD
EWNTISHVRLHTIVEHSDETWKGRTGMITELFRDIEIDTKNTYAIVCGPPIMFKFVCSYLDRLGIPMNRMFVSLERRMHC
GMGKCCRCMVGSTFTCIDGPVFDYWSVMNLKEAI
>Mature_274_residues
MKTDMGYKCRITNVVSLTEQEKLFQLHIVDPQERRIFRFKPGQFIMLELPGYGDVPISISSSYSNHEFIELCIRKAGHVT
SALFRTEPGMHVAIRGPFGSSFPMDEIAGHHVLLVAGGLGIAPLRAPLFWINEHRDRFRDVHLLYGAREPSQLLFSYQFD
EWNTISHVRLHTIVEHSDETWKGRTGMITELFRDIEIDTKNTYAIVCGPPIMFKFVCSYLDRLGIPMNRMFVSLERRMHC
GMGKCCRCMVGSTFTCIDGPVFDYWSVMNLKEAI

Specific function: This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- InterPro:   IPR014260 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: 1.5.1.29 [C]

Molecular weight: Translated: 31490; Mature: 31490

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDMGYKCRITNVVSLTEQEKLFQLHIVDPQERRIFRFKPGQFIMLELPGYGDVPISIS
CCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCEEEEEECCCCCCEEEEE
SSYSNHEFIELCIRKAGHVTSALFRTEPGMHVAIRGPFGSSFPMDEIAGHHVLLVAGGLG
CCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCEEEEEECCCC
IAPLRAPLFWINEHRDRFRDVHLLYGAREPSQLLFSYQFDEWNTISHVRLHTIVEHSDET
CCHHHCCEEEEHHHHHHHHEEEEEECCCCHHHEEEEEECCCCCCCHHEEEEEEEECCCCC
WKGRTGMITELFRDIEIDTKNTYAIVCGPPIMFKFVCSYLDRLGIPMNRMFVSLERRMHC
CCCCCCHHHHHHHHCEECCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GMGKCCRCMVGSTFTCIDGPVFDYWSVMNLKEAI
CHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTDMGYKCRITNVVSLTEQEKLFQLHIVDPQERRIFRFKPGQFIMLELPGYGDVPISIS
CCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCEEEEEECCCCCCEEEEE
SSYSNHEFIELCIRKAGHVTSALFRTEPGMHVAIRGPFGSSFPMDEIAGHHVLLVAGGLG
CCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCEEEEEECCCC
IAPLRAPLFWINEHRDRFRDVHLLYGAREPSQLLFSYQFDEWNTISHVRLHTIVEHSDET
CCHHHCCEEEEHHHHHHHHEEEEEECCCCHHHEEEEEECCCCCCCHHEEEEEEEECCCCC
WKGRTGMITELFRDIEIDTKNTYAIVCGPPIMFKFVCSYLDRLGIPMNRMFVSLERRMHC
CCCCCCHHHHHHHHCEECCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GMGKCCRCMVGSTFTCIDGPVFDYWSVMNLKEAI
CHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD(P)H2; FMN [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; FMN; 2 2-octaprenylphenol; O2 [C]

Specific reaction: NAD(P)H2 + FMN = NAD(P) + FMNH2 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1704886; 11677609 [H]