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The map label for this gene is ubiE [C]

Identifier: 119357914

GI number: 119357914

Start: 2460033

End: 2460722

Strand: Direct

Name: ubiE [C]

Synonym: Cpha266_2127

Alternate gene names: 119357914

Gene position: 2460033-2460722 (Clockwise)

Preceding gene: 119357913

Following gene: 119357915

Centisome position: 78.5

GC content: 48.99

Gene sequence:

>690_bases
ATGGGACAAACATTATATAACTGTTCAGTTCTGACTATGATTACCGGAAACCCATTCGAAACGTATGCCGTCGATTACGA
CAAATGGTTTGAAACAGCTGCCGGAGCGAATCTGTTTCAACTCGAACTGGACTGTCTGAAAAAAGCCGTCGATACGAAAA
AAATGCGATGGCTTGAAGTGGGAGTCGGATCAGGCCGTTTTGCCTGTGCACTTGGAATCACTACCGGTGCCGACCCCGCT
CCAGCAATGGTGAAAATCGCTTCCAGCCGTGGCATCGAGACCATAACGGCTCCAGCAGAAGCATTGCCATTCAATGACGC
CTCGTTTGACGGCGTGCTCATATCATGCGCGATCTGCTTTGTGCAGAACCCGACGCAAGCCTTGGTCGAATGTCATCGGG
TTCTCAAGGAAGGAGGACAACTGGTCATCGGGTTTATTCCTTCAGACAGCCGGTGGGGAGAGTACCATGCCCAAAGAGGA
AAAGAGGGAAACCCGTTTTATGCAGCAGCACGGTTCTATTCTTCGGCAAAACTCAGGCGTTTGACTGAACGTAATGGATT
TATCTGCAATGCCGGGTATGGCTGCATGCTGCCTTCTCCTGATGCACAGCTTGATAATGACGGCTTGCATCGGAAAGCAG
GCATGGACAAAGGGTTCATGGTGCTTTCGTTTTATAAAAAAAACATATAA

Upstream 100 bases:

>100_bases
CTCTGGAACACGGTTGATCAGAAAGCGGCATACCGGACAAAGAGTACCAGGCACTGGCCGTCCGGGTCGTTGATAGCAAC
CGTGTCATTACATTCTGAAT

Downstream 100 bases:

>100_bases
CAGCAAGTAACATGATGAAAGTCGGTATAATCCGCTGCCAGCAGACGGAAGACATGTGCCAGGGGAATACGGATTTCAAG
GTCGCGTCAACAGGCAGGAT

Product: methyltransferase type 11

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MGQTLYNCSVLTMITGNPFETYAVDYDKWFETAAGANLFQLELDCLKKAVDTKKMRWLEVGVGSGRFACALGITTGADPA
PAMVKIASSRGIETITAPAEALPFNDASFDGVLISCAICFVQNPTQALVECHRVLKEGGQLVIGFIPSDSRWGEYHAQRG
KEGNPFYAAARFYSSAKLRRLTERNGFICNAGYGCMLPSPDAQLDNDGLHRKAGMDKGFMVLSFYKKNI

Sequences:

>Translated_229_residues
MGQTLYNCSVLTMITGNPFETYAVDYDKWFETAAGANLFQLELDCLKKAVDTKKMRWLEVGVGSGRFACALGITTGADPA
PAMVKIASSRGIETITAPAEALPFNDASFDGVLISCAICFVQNPTQALVECHRVLKEGGQLVIGFIPSDSRWGEYHAQRG
KEGNPFYAAARFYSSAKLRRLTERNGFICNAGYGCMLPSPDAQLDNDGLHRKAGMDKGFMVLSFYKKNI
>Mature_228_residues
GQTLYNCSVLTMITGNPFETYAVDYDKWFETAAGANLFQLELDCLKKAVDTKKMRWLEVGVGSGRFACALGITTGADPAP
AMVKIASSRGIETITAPAEALPFNDASFDGVLISCAICFVQNPTQALVECHRVLKEGGQLVIGFIPSDSRWGEYHAQRGK
EGNPFYAAARFYSSAKLRRLTERNGFICNAGYGCMLPSPDAQLDNDGLHRKAGMDKGFMVLSFYKKNI

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 25020; Mature: 24889

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQTLYNCSVLTMITGNPFETYAVDYDKWFETAAGANLFQLELDCLKKAVDTKKMRWLEV
CCCEEECCEEEEEEECCCCEEEEECHHHHHHHHCCCCEEEEEHHHHHHHHHHHHEEEEEE
GVGSGRFACALGITTGADPAPAMVKIASSRGIETITAPAEALPFNDASFDGVLISCAICF
ECCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEECCHHHCCCCCCCCCHHHHEEHHHH
VQNPTQALVECHRVLKEGGQLVIGFIPSDSRWGEYHAQRGKEGNPFYAAARFYSSAKLRR
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
LTERNGFICNAGYGCMLPSPDAQLDNDGLHRKAGMDKGFMVLSFYKKNI
HHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
GQTLYNCSVLTMITGNPFETYAVDYDKWFETAAGANLFQLELDCLKKAVDTKKMRWLEV
CCEEECCEEEEEEECCCCEEEEECHHHHHHHHCCCCEEEEEHHHHHHHHHHHHEEEEEE
GVGSGRFACALGITTGADPAPAMVKIASSRGIETITAPAEALPFNDASFDGVLISCAICF
ECCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEECCHHHCCCCCCCCCHHHHEEHHHH
VQNPTQALVECHRVLKEGGQLVIGFIPSDSRWGEYHAQRGKEGNPFYAAARFYSSAKLRR
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
LTERNGFICNAGYGCMLPSPDAQLDNDGLHRKAGMDKGFMVLSFYKKNI
HHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]