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The map label for this gene is trpGD [H]

Identifier: 119357829

GI number: 119357829

Start: 2356749

End: 2357312

Strand: Reverse

Name: trpGD [H]

Synonym: Cpha266_2037

Alternate gene names: 119357829

Gene position: 2357312-2356749 (Counterclockwise)

Preceding gene: 119357830

Following gene: 119357828

Centisome position: 75.22

GC content: 48.94

Gene sequence:

>564_bases
ATGATTCTTGTTATTGATAATTATGATTCGTTTACCTATAACCTGGTACAGTATATCGGCGAGTCCGGAGTGGATGTTGA
GGTGTTCAGGAACGACGAGATAACCGTTTCCCGGATTCTCGAGCTTGCTCCTGATAAAATTGTCATTTCGCCCGGTCCGG
GAACGCCCGATGATGCCGGTATATCCGTTTCGCTGATCAATGCGGTAAAGGGGCGTATTCCTCTGCTCGGAGTCTGCCTC
GGGCATCAGTCAATCGGTTCGGCTCTCGGGGGGAGAGTGGTGAGGGCTGCCAGGATCATGCATGGAAAAACTTCGATGGT
TTTTCATGATGGCACGGGTATTTTTAGCGGTGTCGATAATCCTTTTGTCGCTACCCGGTATCACTCGTTAATTGTGGAGC
GCGCAACGCTTCCTGATGTTCTTGAGGTGCGGGCCTGGACTGACGATGGAGTTATTATGGGTATGGACTCAGTTGAGCTC
AAGTTATACGGTGTGCAGTTTCATCCGGAATCGATTATGACCGGCGAGGGAAAAAAGATTATCAAGAACTTTCTTTCGCT
GTAA

Upstream 100 bases:

>100_bases
GGGTTTCCATGAGCCTTTCGTATGAGGCTATGTTCCGTTTTCTTGCCTTGCGGGAGCAGGGTGGAGAGGTTTTTATCTAA
CTCATTAGCCGGTTTTCTGC

Downstream 100 bases:

>100_bases
CGGGTAGTCGCTCTCTTTACGTTTATTCAAGGAAAAATATCTCGGGGAAAAAAGAGGAAAAAGGGTATTCTTTCAGTACA
GATGGTTGAACGGATTTTTT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILVIDNYDSFTYNLVQYIGESGVDVEVFRNDEITVSRILELAPDKIVISPGPGTPDDAGISVSLINAVKGRIPLLGVCL
GHQSIGSALGGRVVRAARIMHGKTSMVFHDGTGIFSGVDNPFVATRYHSLIVERATLPDVLEVRAWTDDGVIMGMDSVEL
KLYGVQFHPESIMTGEGKKIIKNFLSL

Sequences:

>Translated_187_residues
MILVIDNYDSFTYNLVQYIGESGVDVEVFRNDEITVSRILELAPDKIVISPGPGTPDDAGISVSLINAVKGRIPLLGVCL
GHQSIGSALGGRVVRAARIMHGKTSMVFHDGTGIFSGVDNPFVATRYHSLIVERATLPDVLEVRAWTDDGVIMGMDSVEL
KLYGVQFHPESIMTGEGKKIIKNFLSL
>Mature_187_residues
MILVIDNYDSFTYNLVQYIGESGVDVEVFRNDEITVSRILELAPDKIVISPGPGTPDDAGISVSLINAVKGRIPLLGVCL
GHQSIGSALGGRVVRAARIMHGKTSMVFHDGTGIFSGVDNPFVATRYHSLIVERATLPDVLEVRAWTDDGVIMGMDSVEL
KLYGVQFHPESIMTGEGKKIIKNFLSL

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=56.7567567567568, Blast_Score=227, Evalue=3e-61,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=38.2978723404255, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=24.7368421052632, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=47.5935828877005, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=34.7619047619048, Blast_Score=92, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281365319, Length=139, Percent_Identity=29.4964028776978, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 20273; Mature: 20273

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNYDSFTYNLVQYIGESGVDVEVFRNDEITVSRILELAPDKIVISPGPGTPDDAG
CEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEHHHHHHCCCCEEEEECCCCCCCCCC
ISVSLINAVKGRIPLLGVCLGHQSIGSALGGRVVRAARIMHGKTSMVFHDGTGIFSGVDN
EEEEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCC
PFVATRYHSLIVERATLPDVLEVRAWTDDGVIMGMDSVELKLYGVQFHPESIMTGEGKKI
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEEEEEECCCCEECCCCHHH
IKNFLSL
HHHHHCC
>Mature Secondary Structure
MILVIDNYDSFTYNLVQYIGESGVDVEVFRNDEITVSRILELAPDKIVISPGPGTPDDAG
CEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEHHHHHHCCCCEEEEECCCCCCCCCC
ISVSLINAVKGRIPLLGVCLGHQSIGSALGGRVVRAARIMHGKTSMVFHDGTGIFSGVDN
EEEEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCC
PFVATRYHSLIVERATLPDVLEVRAWTDDGVIMGMDSVELKLYGVQFHPESIMTGEGKKI
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEEEEEECCCCEECCCCHHH
IKNFLSL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]