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The map label for this gene is engA

Identifier: 119357805

GI number: 119357805

Start: 2325378

End: 2326691

Strand: Direct

Name: engA

Synonym: Cpha266_2013

Alternate gene names: 119357805

Gene position: 2325378-2326691 (Clockwise)

Preceding gene: 119357799

Following gene: 119357806

Centisome position: 74.2

GC content: 49.85

Gene sequence:

>1314_bases
ATGAAACCTCTCATCGCTATCGTTGGCCGGCCGAATGTCGGAAAGTCGATGCTTTTCAACAGAATACTTCGCGAAAAAAG
CGCCATTGTAGACAGTACGCCCGGCGTCACCAGAGACCGCCACATCTCTCCCGGAGAGTGGCAGGGAAAACAATTTCTTC
TTATGGATACCGGCGGTTACTGCCCCGAAGGGGATGTGATCAGCATGGCTATGCTCGAACAAACGCTGATGGCTATCCGC
GACGCCGATATCATCCTCTTTCTTGCCGATGTACGATCAGGACTAACCTACGACGACCTTGAAATCAGCAAGCTTCTGCA
GCGGACATTCCAGCACAAGCAGATCTTTTTTGCGGTCAACAAGGTTGAAACCCCGCAACTTTCCATCGATGCGGAATCAT
TTGTCAGTACCGGTTTCACGAAACCCTATTTCGTTTCGGCAAGAGACGGCAGCGGCGTCGCCGAACTGCTTGACGATATG
CTTGATTCGTTGCCCGTCCAGGAAAAACAACTCGTCGAAAAAGACCTGCCGACAAATCTCGCCGTTGTCGGACGTCCCAA
TGTCGGCAAATCAAGTTTCGTCAATGCCCTGCTCGGAGCAAACCGCCTGATCGTGTCAGACATACCAGGCACCACGCGTG
ATGCTATCGACAGCCGCTTTACCCGCAAAAAACAGGATTTCGTCCTGATAGACACGGCCGGACTGAGAAAACGCACCAAA
ATCGACGCCGGCATCGAGTACTACAGCTCCCTGCGAACCGATAAAGCCATCGAGCGATGCGACGTCGCACTGGTAATGAT
CGACGCCAGAACGGGCATCGAAAACCAGGATATGAAAATAATCAATATGGCCGTAGAACGTAAAAGAGGCGTCCTGCTTC
TGATAAACAAATGGGATCTGGTCGAAAAGGATTCCAAAACCAGTGCCCATTACGAAAAAGAGGTTCGCTCGCACATGGGA
AACCTTGCATATATACCCCTGCTGTTTATTTCTGCCCTGACTAAAAAAAATCTCTACAGGGCGATCGATACAGCTCAGGA
GATCAGCGAAAACCGGTCGCGAAAAATCACCACCAGCGCCCTGAACCGCTTTCTTGAAGTTGCCCTTGCAGAAAAACATC
CGTCAACGAAATCCGGCAAGGAGCTGAAAATAAAATACATGACCCAGATCGAAGCACCGTGGCCGGTATTTGCTTTTTTC
TGCAACGATCCCGAACTTCTGCAGACCAATTTCAGAAAGTTTCTTGAAAACAAGCTGCGCGAACACTTCAAACTCGAAGG
AGTAACCGTTTCGCTGCGCTTTTTCAAAAAATGA

Upstream 100 bases:

>100_bases
AATTATTTCACTTAATTCTGCAAATTATACCATTACTACGATCCATGAATTTAACAGGCATCCGAACTTCTTCGTCCTGA
TACATCACAGCTCTGCACTT

Downstream 100 bases:

>100_bases
GCCTGGCAATGCCGGCAGCTAATCTTTCCCTAACCGTTTCATGTAACATAAAAAAACAACCGCATACTCTCCATGATACA
AGAAGAACAAGTGCTTGCCG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGYCPEGDVISMAMLEQTLMAIR
DADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVNKVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDM
LDSLPVQEKQLVEKDLPTNLAVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTK
IDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDLVEKDSKTSAHYEKEVRSHMG
NLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSALNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFF
CNDPELLQTNFRKFLENKLREHFKLEGVTVSLRFFKK

Sequences:

>Translated_437_residues
MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGYCPEGDVISMAMLEQTLMAIR
DADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVNKVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDM
LDSLPVQEKQLVEKDLPTNLAVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTK
IDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDLVEKDSKTSAHYEKEVRSHMG
NLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSALNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFF
CNDPELLQTNFRKFLENKLREHFKLEGVTVSLRFFKK
>Mature_437_residues
MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGYCPEGDVISMAMLEQTLMAIR
DADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVNKVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDM
LDSLPVQEKQLVEKDLPTNLAVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTK
IDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDLVEKDSKTSAHYEKEVRSHMG
NLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSALNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFF
CNDPELLQTNFRKFLENKLREHFKLEGVTVSLRFFKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=463, Percent_Identity=34.1252699784017, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=40.2173913043478, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=169, Percent_Identity=33.1360946745562, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHLPD (A1BHZ8)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912449.1
- ProteinModelPortal:   A1BHZ8
- SMR:   A1BHZ8
- STRING:   A1BHZ8
- GeneID:   4569540
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2013
- NMPDR:   fig|290317.7.peg.2125
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49417; Mature: 49417

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
CPEGDVISMAMLEQTLMAIRDADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVN
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHCEEEEEEC
KVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDMLDSLPVQEKQLVEKDLPTNL
CCCCCCEECCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCE
AVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTK
EEEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHH
IDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDL
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
VEKDSKTSAHYEKEVRSHMGNLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSA
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFFCNDPELLQTNFRKFLENKLR
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
EHFKLEGVTVSLRFFKK
HHHEECCEEEEEEEECC
>Mature Secondary Structure
MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
CPEGDVISMAMLEQTLMAIRDADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVN
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHCEEEEEEC
KVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDMLDSLPVQEKQLVEKDLPTNL
CCCCCCEECCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCE
AVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTK
EEEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHH
IDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDL
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
VEKDSKTSAHYEKEVRSHMGNLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSA
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFFCNDPELLQTNFRKFLENKLR
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
EHFKLEGVTVSLRFFKK
HHHEECCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA