| Definition | Chlorobium phaeobacteroides DSM 266 chromosome, complete genome. |
|---|---|
| Accession | NC_008639 |
| Length | 3,133,902 |
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The map label for this gene is gdhB [H]
Identifier: 119357793
GI number: 119357793
Start: 2314410
End: 2315234
Strand: Reverse
Name: gdhB [H]
Synonym: Cpha266_2000
Alternate gene names: 119357793
Gene position: 2315234-2314410 (Counterclockwise)
Preceding gene: 119357794
Following gene: 119357792
Centisome position: 73.88
GC content: 49.45
Gene sequence:
>825_bases ATGGGAAAGCTCGATAACAAGGTTTCTGTTATTACCGGATCAACGCGTGGTATCGGAAAGGCTATAGCCCAGGCATTTGT CTCGGAAGGATCGAAAGTAGTCATTACCTCCTCTTCGCAAGCGAATGTCGACGCAACTGTATCGGAATTTCCACCAGGCT CGGTGTATGGACATGTTTGTGATGTTGCCTCTTTTCGGGAAATGGAGCGGCTTGTCGATGCCTCGGTTGGCAAATTTGGC CGGATTGACTGTTTTATCAATAATGCGGGCATTTCGGAGCCGTTCTGTAATATTACCGGTGGCGATCCGGATATCTGGGG GAGGGTTATTGATACCAATCTCAAAGGTACCTACTACGGTTGCCGGGCAGCCATCGGTTATTTCCAGAGAGAAGATATTC CGGGCAAGATTATCACGATGGCGGGTTCAGGAACCGATAAGGGATCGAATACCCCGTATATCAGTGCATATGGATCCACC AAGGCTGCTATTGCCCGATTTACCTCGGCGATTGCTGAAGAGTATCGGCATACCGGTATTTCGATCATGCTGCTTCATCC CGGTCTCGTTCGGACGGGCATGGTCAGTGCAGAACAGCCTACCCCTGAACTGCTTCGGCAGCTTTCCGTTTTCAACACTA TTCTCGATATTTTTGCGCAGCCTCCATCGGTAGCCGCCGATCTTGCCGTAAAAATGGCTTCCGGCTGGAGCGACGGAAAA ACAGCTCTTTATCTTTCTGCTCTTACCGGCTGGAGAAAAAAAAGGTTGTTGCTGACCTATCCCTTCCGTAAACTGTTCAA CAGTATCGATCGTCGAACCTACTAA
Upstream 100 bases:
>100_bases CTCTCTCTTGATGAATATGCGATCGGGCGACCTGAGCTGATGGCGATGGTTGCTGTCGAAAATGCTAAAAAACAGCACTC CTGACCAGGAAACTTCAATC
Downstream 100 bases:
>100_bases CGTTCATGGAGCCACACCATGCGGAACAGAAGCATTACAGCAGTTACCTTATTCACTCTTGTCTGCATTTTTGTTACCGG CTGCTATAGCCTGAAAGGGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 274; Mature: 273
Protein sequence:
>274_residues MGKLDNKVSVITGSTRGIGKAIAQAFVSEGSKVVITSSSQANVDATVSEFPPGSVYGHVCDVASFREMERLVDASVGKFG RIDCFINNAGISEPFCNITGGDPDIWGRVIDTNLKGTYYGCRAAIGYFQREDIPGKIITMAGSGTDKGSNTPYISAYGST KAAIARFTSAIAEEYRHTGISIMLLHPGLVRTGMVSAEQPTPELLRQLSVFNTILDIFAQPPSVAADLAVKMASGWSDGK TALYLSALTGWRKKRLLLTYPFRKLFNSIDRRTY
Sequences:
>Translated_274_residues MGKLDNKVSVITGSTRGIGKAIAQAFVSEGSKVVITSSSQANVDATVSEFPPGSVYGHVCDVASFREMERLVDASVGKFG RIDCFINNAGISEPFCNITGGDPDIWGRVIDTNLKGTYYGCRAAIGYFQREDIPGKIITMAGSGTDKGSNTPYISAYGST KAAIARFTSAIAEEYRHTGISIMLLHPGLVRTGMVSAEQPTPELLRQLSVFNTILDIFAQPPSVAADLAVKMASGWSDGK TALYLSALTGWRKKRLLLTYPFRKLFNSIDRRTY >Mature_273_residues GKLDNKVSVITGSTRGIGKAIAQAFVSEGSKVVITSSSQANVDATVSEFPPGSVYGHVCDVASFREMERLVDASVGKFGR IDCFINNAGISEPFCNITGGDPDIWGRVIDTNLKGTYYGCRAAIGYFQREDIPGKIITMAGSGTDKGSNTPYISAYGSTK AAIARFTSAIAEEYRHTGISIMLLHPGLVRTGMVSAEQPTPELLRQLSVFNTILDIFAQPPSVAADLAVKMASGWSDGKT ALYLSALTGWRKKRLLLTYPFRKLFNSIDRRTY
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=191, Percent_Identity=32.4607329842932, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=30.5263157894737, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI19923817, Length=198, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI5031737, Length=195, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI31542939, Length=239, Percent_Identity=25.1046025104602, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7705925, Length=196, Percent_Identity=26.0204081632653, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723750, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI109715829, Length=202, Percent_Identity=26.2376237623762, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=28.5, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI40254992, Length=189, Percent_Identity=25.3968253968254, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI87082100, Length=213, Percent_Identity=33.8028169014084, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=27.1794871794872, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789208, Length=214, Percent_Identity=24.2990654205607, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787905, Length=94, Percent_Identity=35.1063829787234, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1787526, Length=210, Percent_Identity=21.4285714285714, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786812, Length=186, Percent_Identity=29.0322580645161, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=27.7227722772277, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17561402, Length=195, Percent_Identity=31.2820512820513, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.4090909090909, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560332, Length=210, Percent_Identity=30.4761904761905, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=27.0935960591133, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=220, Percent_Identity=27.7272727272727, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17562908, Length=204, Percent_Identity=26.4705882352941, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17544670, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562904, Length=208, Percent_Identity=29.3269230769231, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193204405, Length=217, Percent_Identity=28.110599078341, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538486, Length=212, Percent_Identity=27.8301886792453, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17565030, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=26.2376237623762, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560676, Length=212, Percent_Identity=22.1698113207547, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17563726, Length=228, Percent_Identity=25.8771929824561, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560150, Length=205, Percent_Identity=24.8780487804878, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI86565303, Length=213, Percent_Identity=23.0046948356808, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17551412, Length=202, Percent_Identity=27.7227722772277, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562990, Length=206, Percent_Identity=25.2427184466019, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17538480, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17562910, Length=210, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI72000259, Length=221, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322226, Length=256, Percent_Identity=28.125, Blast_Score=80, Evalue=5e-16, Organism=Saccharomyces cerevisiae, GI6322227, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=8e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=217, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=29.3814432989691, Blast_Score=102, Evalue=4e-22, Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=31.4720812182741, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24641232, Length=241, Percent_Identity=27.3858921161826, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI116007236, Length=248, Percent_Identity=26.6129032258064, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24641388, Length=241, Percent_Identity=27.3858921161826, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI281364494, Length=207, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI18859837, Length=154, Percent_Identity=30.5194805194805, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI28571387, Length=234, Percent_Identity=26.0683760683761, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI17737361, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=26.1538461538462, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24663911, Length=241, Percent_Identity=24.896265560166, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24639444, Length=230, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI21357041, Length=200, Percent_Identity=25.5, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.47 [H]
Molecular weight: Translated: 29570; Mature: 29439
Theoretical pI: Translated: 9.28; Mature: 9.28
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGKLDNKVSVITGSTRGIGKAIAQAFVSEGSKVVITSSSQANVDATVSEFPPGSVYGHVC CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEHHCCCCCCHHHHHH DVASFREMERLVDASVGKFGRIDCFINNAGISEPFCNITGGDPDIWGRVIDTNLKGTYYG HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCEEEECCCCCCHHH CRAAIGYFQREDIPGKIITMAGSGTDKGSNTPYISAYGSTKAAIARFTSAIAEEYRHTGI HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCE SIMLLHPGLVRTGMVSAEQPTPELLRQLSVFNTILDIFAQPPSVAADLAVKMASGWSDGK EEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC TALYLSALTGWRKKRLLLTYPFRKLFNSIDRRTY CEEEEEHHHCCCCCCEEEECCHHHHHHHHHCCCC >Mature Secondary Structure GKLDNKVSVITGSTRGIGKAIAQAFVSEGSKVVITSSSQANVDATVSEFPPGSVYGHVC CCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEHHCCCCCCHHHHHH DVASFREMERLVDASVGKFGRIDCFINNAGISEPFCNITGGDPDIWGRVIDTNLKGTYYG HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCEEEECCCCCCHHH CRAAIGYFQREDIPGKIITMAGSGTDKGSNTPYISAYGSTKAAIARFTSAIAEEYRHTGI HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCE SIMLLHPGLVRTGMVSAEQPTPELLRQLSVFNTILDIFAQPPSVAADLAVKMASGWSDGK EEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC TALYLSALTGWRKKRLLLTYPFRKLFNSIDRRTY CEEEEEHHHCCCCCCEEEECCHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 6420184; 3134196; 6413208; 6432532 [H]